A preparation method of a Levamlodipine besylate tablet includes pulverizing Levamlodipine besylate, a filler and a disintegrant, sieving, mixing, adding a lubricant, granulating, and tableting. The invention reduces the amount of related substance of the Levamlodipine besylate tablet, and improves stability. The method uses a fluidized bed granulation step to prepare the Levamlodipine besylate tablet, so as to simplify preparation step, shorten time, optimize process parameter, significantly increase the dissolution of the product and improve quality. The inventive method is suitable for industrial production.