166 results about "Cefixime" patented technology

The invention relates to a cefixime compound and the preparation method thereof. In the preparation method of the cefixime compound, a cefixime crude product prepared by the prior art is processed to gain comparatively purer cefixime compound by the following procedures: aqueous alkali is added to raw materials of the cefixime crude product, or the cefixime crude product is dissolved in organic solvent and reacts with the added aqueous alkali, the pH value is adjusted, and the reaction continues until clarification to obtain cefixime saline solution; and the cefixime elaboration product can be obtained after the sequential operations of adding active carbon for adsorption and filtration, adding acid solution into filter liquor, adjusting the pH value, separating out crystals, filtrating, rinsing and drying.

The invention discloses a cefixime oral administration mixed suspension and a preparation method thereof, in order to meet the requirement of special medicament taking crowds on the taking of cefixime. The cefixime oral administration mixed suspension per 100ml comprises the following components: 0.5-4.0g of cefixime, larger than 0-20.0g of thickening suspension assistant agent, a cosolvent, a flavoring agent, a preservative and the balance of non-aqueous liquid medium. The preparation method comprises the following steps of: dissolving the preservative into the cosolvent; adding the thickening suspension assistant agent into the non-aqueous liquid medium, stirring and dissolving; adding solutions of the flavoring agent, the preservative and the cosolvent uniformly stirring; and adding cefixime micropowder and uniformly stirring and spreading. Compared with the prior art, the unstable cefixime in water is made into the oral administration mixed suspension by using non-aqueous liquid as a dispersing medium, and the invention solves the problem of stability, has good taste and simple preparation method, is convenient for children, old people and a dysphagia patient to accept and is suitable for industrialized production.