The present invention relates to a pharmaceutical composition, preferably a pharmaceutical
dosage form, comprising at least two separate compartments, wherein one compartment contains a composition comprising
metformin or a pharmaceutically acceptable salt thereof and wherein another compartment contains a composition comprising
sitagliptin.The present invention also relates to a process for preparing dosage forms comprising
metformin or a pharmaceutically acceptable salt thereof and
sitagliptin or a pharmaceutically acceptable salt thereof, the process comprising the steps of:a) providing one composition containing
metformin or a pharmaceutically acceptable salt thereof and optionally also
sitagliptin,b) providing a further composition containing sitagliptin or a pharmaceutically acceptable salt thereof and optionally also metformin, andc) combining the compositions to form compartments.The present invention also refers to a process for preparing dosage forms comprising at least one compartment comprising metformin or a pharmaceutically acceptable salt thereof and sitagliptin or a pharmaceutically acceptable salt thereof, the process comprises providing a composition containing metformin or a pharmaceutically acceptable salt thereof, and sitagliptin or a pharmaceutically acceptable salt thereof, and a matrix agent.Moreover, the present invention related to a
dosage form obtained by said process, and to the use of said
dosage form for the treatment of diabetes.