Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

435 results about "Thioketone" patented technology

Thioketones (also known as thiones or thiocarbonyls) are organosulfur compounds related to conventional ketones in which the oxygen has been replaced by a sulfur. Instead of a structure of R₂C=O, thioketones have the structure R₂C=S, which is reflected by the prefix "thio-" in the name of the functional group. Unhindered alkylthioketones typically tend to form polymers or rings.

Pharmaceutical co-crystal compositions

A pharmaceutical composition comprising a co-crystal of an API and a co-crystal former; wherein the API has at least one functional group selected from ether, thioether, alcohol, thiol, aldehyde, ketone, thioketone, nitrate ester, phosphate ester, thiophosphate ester, ester, thioester, sulfate ester, carboxylic acid, phosphonic acid, phosphinic acid, sulfonic acid, amide, primary amine, secondary amine, ammonia, tertiary amine, sp2 amine, thiocyanate, cyanamide, oxime, nitrile diazo, organohalide, nitro, s-heterocyclic ring, thiophene, n-heterocyclic ring, pyrrole, o-heterocyclic ring, furan, epoxide, peroxide, hydroxamic acid, imidazole, pyridine and the co-crystal former has at least one functional group selected from amine, amide, pyridine, imidazole, indole, pyrrolidine, carbonyl, carboxyl, hydroxyl, phenol, sulfone, sulfonyl, mercapto and methyl thio, such that the API and co-crystal former are capable of co-crystallizing from a solution phase under crystallization conditions.
Owner:JOHNSON & JOHNSON CONSUMER COPANIES +2

Topical anti-microbial compositions

Disclosed are topical compositions for the treatment of microbial infections on the skin or scalp which include a polyvalent metal salt of pyrithione and include a metal ion source. Also disclosed are methods for treating microbial infections of the skin or scalp using such compositions.
Owner:THE PROCTER & GAMBLE COMPANY +1

Pyrithione biocides enhanced by zinc metal ions and organic amines

The present invention is directed to a stable, soluble, antimicrobial composition concentrate comprising pyrithione or a pyrithione complex in an amount of from about 0.5% to about 30 weight percent, a zinc source in an amount of from about 0.1% to about 10%, and an organic amine component in an amount of from about 30% to about 80%, said percents being based upon the total weight of the composition concentrate. The invention is also directed to methods of controlling the growth of free-living microorganisms or biofilms using the antimicrobial composition of the invention, and products made using the antimicrobial composition of the invention.
Owner:ARCH CHEM INC

Preflux, flux, solder paste and method of manufacturing lead-free soldered body

There is closed a flux which is designed to be used in a soldering using a lead-free and zinc-free solder containing tin as a major component and not containing lead, the soldering being adapted to be applied to a surface portion which is constituted by a copper-based metal and / or a nickel-based metal (excluding the case where the surface portion is constituted by electroless nickel plating), wherein the flux contains at least one kind of material selected from the group consisting of a copper-based metal, a nickel-based metal, an inorganic salt of copper-based metal and / or a nickel-based metal, an inorganic complex of copper-based metal and / or a nickel-based metal, and an organic complex of copper-based metal and / or a nickel-based metal (a metal complex of an organic compound where atoms of N, O and S in amine (excluding nitrogen-containing hetrocyclic compounds), imine (excluding nitrogen-containing hetrocyclic compounds), oxime, ketone, alkoxy and thioketone are coordinated with a metal). There is also closed a method of manufacturing a lead-free soldered body wherein this flux is employed.
Owner:ESE IND S

4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds

InactiveUS20040220402A1BiocideOrganic active ingredientsDiseaseALPHA-2A-ADRENERGIC RECEPTOR
Compounds of Formula 1 where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and / or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and / or sedatory activity. These compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula 1 where X is O also have the advantageous property that they have no or only minimal cardivascular and / or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and / or sedatory activity.
Owner:ALLERGAN INC

Isothiazolinone biocides enhanced by zinc ions

The present invention relates to an antimicrobial composition comprising an isothiazolinone, such as 1,2-benzisothiazolin-3-one, and a zinc compound selected from zinc salts, zinc oxides, zinc hydroxides or combinations thereof. Useful zinc salts include for example, oxides, sulfates, chlorides, and combinations thereof. In use, the zinc from the zinc compound enhances the antimicrobial activity to the isothiazolin-containing composition. This enhancement permits achieving the desired antimicrobial activity at a lower usage rate than is achieved using the isothiazolinone in the absence of the zinc compound. The antimicrobial composition can also contain co-biocides, such as pyrithiones, including zinc pyrithione or copper pyrithione.
Owner:ARCH CHEM INC

Antifouling paint composition, antifouling paint films, and, ships, underwater underwater structures, fishing gear and fishing nets covered with the films

An antifouling coating composition substantially not containing cuprous oxide and organotins, characterized by comprising (A) a metal-containing copolymer obtained by copolymerization of a polymerizable unsaturated monomer (a1) containing a metal and an unsaturated monomer (a2) capable of radical polymerization containing no metals; (B) 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one; and (C) a metal pyrithione compound. There are provided an antifouling coating composition, antifouling coating film and, covered with the antifouling coating film, marine vessel, underwater structure and fishing gear or fishing net, which can reduce burdens on the environment, exhibiting excellent antifouling performance, and which excel in not only uniform wasting of coating film but also capability of maintaining antifouling performance of coating film for a prolonged period of time.
Owner:CHUGOKU MARINE PAINTS

Coated metal pyrithione particles for treatment of microorganisms

A composition comprising coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent. The composition is characterized by enhanced anti-fungal and anti-dandruff efficacy in shampoos. Also disclosed is a personal care composition, preferably a shampoo, containing a topical carrier and coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent.
Owner:ARCH CHEM INC +1

Novel pyrithione complex compound, process for producing the same and use thereof

Zinc pyrithione and copper pyrithione are highly evaluated in the market as an antidandruff agent for shampoo, or an antifouling agent for ship bottom paint and fish-farming net, or an antibacterial / antifungal agent or preservative / mildewcide for industrial products and household articles. For enhancing the market value thereof, there has been a demand for a product that not only attains an increase in conventional antibacterial / antifungal effects but also exhibits novel bioactive effects and that achieves improvement with respect to problems and drawbacks relating to properties, such as solubility in seawater, and stability, such as thermal stability and weather resistance, of polymer materials. There is provided a novel pyrithione complex compound obtained by converting the conventional pyrithione metal salt to a complex compound with an oxide or hydroxide of metal such as zinc, copper or aluminum. As compared with the conventional pyrithione metal salt, this complex compound exhibits superior antibacterial / antifungal effects, newly realizes a hair-regrowing effect and successfully attains improvement with respect to the solubility in seawater and thermal stability / weather resistance of polymer materials.
Owner:YHS

Antimicrobial and antidandruff composition and application thereof

ActiveCN101966131AImprove the effect of anti-dandruff and sterilizationOvercome the shortcomings of ineffective anti-dandruff, sterilization and anti-itching effectAntibacterial agentsCosmetic preparationsSodium PyrithioneShower gel
The invention discloses an antimicrobial and antidandruff composition and application thereof. The composition comprises a pyrithione polyvalent metal salt and an alkoxy aromatic amidine compound, and preferably comprises zinc pyridine thione and hexamidine isethionate, wherein the weight ratio of the zinc pyridine thione to the hexamidine isethionate in the composition is 1:20-10000:1. The composition can be applied in washing-off systems such as liquid shampoos, hair conditioners, facial cleansers, dermatophytosis removal products or shower gel and the like which have the effects of sterilization and antibiosis. The antimicrobial and antidandruff composition can provide the high-efficiency effect of dandruff removal and sterilization, overcome the defect that the effects of dandruff removal, sterilization and itching relieving are not obvious due to the single use of any one component in the composition under the same condition, and play an excellent role in the dandruff removal, sterilization and itching relieving; and the zinc pyridine thione and the hexamidine isethionate have the synergic effect on the using effect, and the composition is used in products under the same using condition and using amount to reduce the amount used when only single component in the composition is used effectively, so the effects of the dandruff removal and itching relieving can be achieved.
Owner:南京枫华投资管理有限公司

4-(Substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4- (substituted cycloalkylmethyl) imidazol-2-ones and 4- (substituted cycloalkenylmethyl) imidazol-2-ones and related compounds

Compounds of Formula 1 where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and / or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and / or sedatory activity. These compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula 1 where X is O also have the advantageous property that they have no or only minimal cardivascular and / or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and / or sedatory activity.
Owner:ALLERGAN INC

Cleanser composition

A cleanser composition composed of purified water, sodium laureth sulfate, zinc pyrithione, cocamidopropyl betaine, glycerol cocoate, polyquaternium-7, and a cross-linked polyacrylic acid polymer for topical application to an area affected by a skin disorder such as seborrheic dermatitis, perioral dermatitis, rosacea, acne, tinea versicolor, eczema and psoriasis.
Owner:KUNIN AUDREY

4-(Heteroaryl-methyl and substituted heteroaryl-methyl)-imidazole-2-thiones acting as alpha2 adrenergic agonists

InactiveUS20060069143A1Antibacterial agentsOrganic active ingredientsDiseaseAlpha2 adrenergic agonist
Compounds of Formula 1 where the variables have the meaning defined in the specification are agonists of alpha2 adrenergic receptors. Several compounds of the disclosure are specific or selective to alpha2B and / or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors. Additionally some of the claimed compounds have no or only minimal cardivascular and / or sedatory activity. The compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2 adrenergic receptors. Compounds of Formula 1 which have no significant cardiovascular and / or sedatory activity are useful for treating pain and other conditions with minimal side effects.
Owner:ALLERGAN INC

4-(Condensed cyclicmethyl)-imidazole-2-thiones acting as alpha2 adrenergic agonists

InactiveUS20060069144A1Minimal cardiovascularMinimal sedatory activityBiocideSenses disorderDiseaseSide effect
Compounds of Formula 1 where the variables have the meaning defined in the specification are agonists of alpha2 adrenergic receptors. Several compounds of the disclosure are specific or selective to alpha2B and / or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors. Additionally some of the claimed compounds have no or only minimal cardivascular and / or sedatory activity. The compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2 adrenergic receptors. Compounds of Formula 1 which have no significant cardiovascular and / or sedatory activity are useful for treating pain and other conditions with minimal side effects.
Owner:ALLERGAN INC

Synthesis method of sildenafil analog

The invention provides a synthesis method of a sildenafil analog. The chemical name of the sildenafil analog is 5-[2-ethoxy-5-(4-methylpiperazine-1-yl-thiocarbonyl)]phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazol[4,3d]pyrimidine-7-thioketone; the sildenafil analog is prepared from 5-(2-ethoxy)phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazol[4,3-d]pyrimidine-7-one as a raw material through four steps of chemical reactions. The synthesis method of the sildenafil analog is simple in synthesis step operations, economic and environmentally friendly; the yield of each step is above 75% and the total yield is relatively high; the synthesis method is suitable for industrial production.
Owner:JINAN MEILUWEI BIOTECH CO LTD

Medicine for preventing fish saprolegniasis and application thereof

InactiveCN103142592AGood control effectSmall minimum inhibitory concentrationSalicyclic acid active ingredientsAntimycoticsBiotechnologyCarbamate
The invention relates to medicine for preventing fish saprolegniasis and application thereof. The medicine is combination of one or more types of the following materials: industrial biocide containing bromine, pyridine thioketone salts, 3-iodo-2-propynyl-butyl-carbamate, phenol derivatives, compound containing aldehyde group, mildew preventive 10, 10' oxybis-phenoxarsine, prepared rehmannia roots, garden burnet, pomegranate bark, dyer woad leaves and artemisia carvifolia. The medicine is generally low in a minimal inhibitory concentration to saprolegnia bacterial strains, and is suitable for prevention of the saprolegniasis in aquiculture. The Chinese herbal medicine and composition thereof can prevent the saprolegniasis and have the advantages of being free of pollution and a toxic side effect. The medicine is especially suitable for prevention of the saprolegniasis of aquatic livestock of high economic value, such as ornamental fishes. Food security can be effectively ensured, and quality of aquatic products can be improved.
Owner:SHANGHAI OCEAN UNIV

Antifouling coating composition, antifouling coating film, antifouling substrate, and method for improving storage stability of antifouling coating compositions

In one aspect, the invention has an object of providing antifouling coating compositions which have high resistance to fouling, in particular, fouling by slime, can form coating films with excellent properties such as strength and rubber properties, exhibit appropriate viscosity (sprayability and coating film surface leveling properties during spray coating) and sagging resistance, and have high storage stability suppressing deteriorations of these properties. To achieve the object, the invention provides an antifouling coating composition including (A) a diorganopolysiloxane having at least two silanol groups in the molecule, (B) an organosilane and / or a partial hydrolyzate condensate thereof having at least two hydrolyzable groups in the molecule, and (C) a pyrithione metal salt. The antifouling coating composition can be prepared from a kit in the form of a multiple-component system including respective packages of a component including the component (A) and the component (C), and a component including the component (B). In the (kit for the preparation of the) antifouling coating composition, the pyrithione metal salt (C) functions as an effective ingredient for achieving excellent antifouling properties, in particular, anti-sliming properties, and also as an effective ingredient for improving storage stability.
Owner:CHUGOKU MARINE PAINTS

Shampooing cream composition capable of enhancing deposition of anti-dandruff agent

ActiveCN107440935AStrong flocculation strengthHelp to carryCosmetic preparationsHair cosmeticsSodium PyrithioneSuspending Agents
The invention relates to a shampooing composition, and in particular a shampooing cream composition capable of enhancing deposition of an anti-dandruff agent; the composition consists of an anionic surfactant, an ampholytic surfactant, a cationic polysaccharide polymer derivative, zinc pyrithione, a non-volatile conditioning agent, 0.01-10% of a suspending agent and the balance of purified water, wherein the cationic polysaccharide polymer derivative is any one or a compound of the following two derivatives: (i) a cationic cellulose derivative and (ii) a cationic guar gum derivative; the viscosity of a 2% pure water solution of the cationic cellulose derivative is 20000-40000cps and a nitrogen content of the cationic cellulose derivative is 0.8-3.1%; the charge density of the cationic guar gum derivative is 0.5-1.0meq / g and the molecular weight of the cationic guar gum derivative is 400000-1500000g / mol. The shampooing cream composition provided by the invention is good in flocculation phase character and excellent in anti-dandruff agent deposition capacity; and a relatively outstanding anti-dandruff effect is achieved, so that, the shampooing composition, when applied to a user for a long time, can achieve an obvious effect of removing dandruff.
Owner:OPAL COSMETICS HUIZHOU

Method for preparing taurine and substituted taurine

The invention provides a method for preparing taurine and substituted taurine, which takes 1, 3-thiazolidine-2-thioketone and derivants thereof as raw material to prepare taurine and substituted taurine. The method has the advantages that the raw material can be obtained easily, the operation is convenient, the purification through desalination is not needed, and the method is particularly suitable for large-scale industrialized production and can be utilized to prepare optically active substituted taurine. The obtained compound can be used as nutritive matters, medicines, enzyme inhibitors, antimicrobials, surface active agents, plant growth regulators, raw material for preparing sulfono-peptides, etc.
Owner:BEIJING UNIV OF CHEM TECH

Nucleotide and nucleoside therapeutic compositions and uses related thereto

This disclosure relates to nucleotide and nucleoside therapeutic compositions and uses in treating infectious diseases, viral infections, and cancer, where the base of the nucleotide or nucleoside contains at least one thiol, thione or thioether.
Owner:EMORY UNIVERSITY

4-(Phenylmethyl and substituted phenylmethyl)-imidazole-2-thiones acting as specific alpha2 adrenergic agonists

Compounds of Formula 1where the variables have the meaning defined in the specification are agonists of alpha2 adrenergic receptors. Several compounds of the disclosure are specific or selective to alpha2B and / or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors. Additionally some of the claimed compounds have no or only minimal cardivascular and / or sedatory activity. The compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2 adrenergic receptors. Compounds of Formula 1 which have no significant cardiovascular and / or sedatory activity are useful for treating pain and other conditions with minimal side effects.
Owner:ALLERGAN INC

Additive for electrolytic copper foil, ultra-low peak HVLP copper foil and preparation method of ultra-low peak HVLP copper foil

InactiveCN110724979ASolve the problem of high roughnessImprove ductilityElectroforming processesElectrolysisThiazole
The invention relates to the technical field of electrolytic copper foils, in particular to an additive for electrolytic copper foil, an ultra-low peak HVLP copper foil and a preparation method of theultra-low peak HVLP copper foil. The additive comprises at least four of an acid copper throwing agent, a terahydrozoline thioketone, a monosodium salt, a 3,3'-dithiobis-1-propanesulfonicacidisodiumsalt, a collagen and a cowhide polypeptide as well as chloridion. The additive for the electrolytic copper foil, the ultra-low peak HVLP copper foil and the preparation method of the ultra-low peak HVLP copper foil have the advantages of low roughness, excellent mechanical property and good oxidation resistance.
Owner:东强(连州)铜箔有限公司

Method for preparing quinazoline-2-thioketone

The invention discloses a method for preparing quinazoline-2-thioketone. The method comprises the steps of: under the catalysis of silicoamino rate-earth compound [(Me3Si)2N]3Ln(mu-Cl)Li(THF)3s erving as a catalyst; and preparing the quinazoline-2-thioketone by addition reaction of catalytic o-amino ethyl cinnamate and isothiocyanate, wherein Ln represents a triad rate-earth metal ion and is one of lanthanum, neodymium, samarium or ytterbium; (Me3Si)2N represents trimethyl silicoamino; mu- represents a bridged bond; THF represents tetrahydrofuran; the chemical structural formula of the o-amino ethyl cinnamate and isothiocyanate is shown in the specification; and the general formula of the chemical structure of the isothiocyanate is RNCS. In the method, the catalyst is good in chemical selectivity, high in reactivity, mild in reaction condition and in no need of a solvent, and the yield of a target product is high.
Owner:SUZHOU UNIV

Preparation method of prothioconazole intermediate

The invention relates to a preparation method of a prothioconazole intermediate. The method sequentially comprises the following steps: enabling a compound I and a compound II to react at the temperature of 20-120 DEG C in presence of a solvent; after the reaction is finished, treating to obtain a compound III; enabling the compound III to react with XOH, formaldehyde, YSCN and sodium hydrogen sulfate at the temperature of 10-80 DEG C in presence of a solvent so as to obtain a compound IV 2-(1-chloro-cyclopropyl-1-yl)-1-(2-chlorphenyl)-2-hydroxyl-3-(1,2,4-triazolidine-5-thioketone-1-yl)-propane, namely, the prothioconazole intermediate. Compared with the reported methods, the preparation method provided by the invention not only enables the intermediate to be more stable, but also reduces the amount of reagents, simplifies the operation steps, avoids the occurrence of side effects, increases the reaction efficiency and is less in pollution caused by the three wastes, thus being environmentally friendly and suitable for industrial production.
Owner:JIANGSU SEVENCONTINENT GREEN CHEM CO LTD

3H-1,2-dithio-cyclopentene-3-thioketone compound and application thereof

The invention relates to the field of medicaments, and in particular relates to a 3H-1,2-dithio-cyclopentene-3-thioketone compound and an application thereof. The 3H-1,2-dithio-cyclopentene-3-thioketone compound disclosed by the invention has a structure shown in a formula I or a formula II and is a compound with a completely-new structure. Proved by experiments, the 3H-1,2-dithio-cyclopentene-3-thioketone compound has a direct protection role on neurons on a cell model, and can obviously restrain excessive inflammatory responses of inflammatory cells in the cerebrum; and by using 3H-1,2-dithio-cyclopentene-3-thioketone, focal cerebral ischemia cerebral infarction volume of a mouse can be obviously reduced in an animal model. Therefore, the invention provides the 3H-1,2-dithio-cyclopentene-3-thioketone compound and the application of acceptable slat of the 3H-1,2-dithio-cyclopentene-3-thioketone compound on the pharmacy aspect to the preparation of medicaments for preventing or treating a cerebral apoplexy disease.
Owner:SUZHOU UNIV

Antibacterial flame retardant coating and preparation method thereof

InactiveCN104927491AImprove surface antimicrobial propertiesSimple processFireproof paintsAntifouling/underwater paintsFiberMeth-
The invention relates to an antibacterial flame retardant coating. The antibacterial flame retardant coating comprises the following components in parts by weight: 6-10 parts of zinc pyrithione, 15-30 parts of chitosan biguanidine hydrochloride, 8-16 parts of methylphenyl silicone resins, 10-25 parts of nanometer silver powder, 8-10 parts of a phosphate flame retardant, 4-10 parts of dihexadecyl peroxodicarbonate, 12-20 parts of benzyl butyl phthalate, 0.5-1 part of superfine acrylate rubber powder, 0.1-0.5 part of dimethyl methylphosphate, 5-15 parts of aluminium silicate fibers, and 1-3 parts of zinc oxide. The antibacterial flame retardant coating disclosed by the invention is prepared under normal temperature and normal pressure, and extra equipment is not needed; the technology is simple, and the production cost is low. After the antibacterial flame retardant coating disclosed by the invention is used, the antibacterial performance of surfaces of materials can be effectively improved, and the materials have good flame retardance; the antibacterial flame retardant coating integrally has favorable antibacterial flame retardance, and can be used according to needs.
Owner:龚灿锋
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products