43results about How to "Physical improvement" patented technology

Described are implantable devices and methods for treating various disorders of the pelvic floor by means of electrical stimulation of the pudendal or other nerves, and optional means for delivering drugs in association therewith. A method of precisely positioning and implanting a medical electrical lead so as to provide optimal stimulation of the pudendal nerve or a portion thereof is also described. Placement of a stimulation lead next to or on the pudendal nerve may be performed using conventional prior art techniques through gross anatomical positioning, but usually does not result in truly optimal lead placement. One method of the present invention utilizes neurophysiological monitoring to assess the evoked responses of the pudendal nerve, and thereby provide a method for determining the optimal stimulation site. Additionally, one or more electrical stimulation signals are applied, and optionally one or more drugs are infused, injected or otherwise administered, to appropriate portions of a patient's pelvic floor and pudendal nerve or portions thereof in an amount and manner effective to treat a number of disorders, including, but not limited to, urinary and/or fecal voiding dysfunctions such as constipation, incontinence disorders such as urge frequency and urinary retention disorders, sexual dysfunctions such as orgasmic and erectile dysfunction, pelvic pain, prostatitis, prostatalgia and prostatodynia.

An electrical connector for connecting low voltage device to an electrified ceiling framework. The connector includes a connector body and a conductive member attached to the connector body. The conductive member includes a contact portion configured to provide electrical contact to a conductive surface of the electrified ceiling framework. The connector is also configurable in a first position and a second position. The first position permits insertion of a portion of the connector into an opening in the electrified ceiling framework. The second position engages the electrified ceiling framework to provide an electrical connection and mechanical support to the connector and devices that may be attached thereto.

Novel hydrophobic composites, particularly hydrophobic particulates and free-flowing hydrophobic aggregates and methods utilizing same are disclosed.

A novel crystalline form of sitagliptin sulfate is provided. In addition, a method for obtaining the crystalline form, pharmaceutical compositions comprising the novel crystalline form and the crystalline form for use as a medicament are provided.

Composition for preparing a biodegradable polyurethane-based foam and a biodegradable polyurethane foam, comprising mixtures based on poly(hydroxybutyrate) polymer, polyols of renewable source, isocyanates and additives, with the object of preparing biodegradable polyurethane foams. In the process, the poly(hydroxybutyrate) plus the polyol, the isocyanate and the additives are previously mixed in specific mixers; once the homogenization is reached, the mixture is poured in mold for growing. After curing, the resulting product presents foam characteristics, with its density, toughness and cell size varying according to the proportion of the reagents and allowing the manufacture of several products.

There is provided a particulate conductive filler which comprises a conductive metal coating formed over a coarse carbon-based core such as graphite between 350 and 1000 microns in size. The conductive filler is used in conjunction with a polymer matrix such as an elastomer typified by silicone elastomer to form composite materials for conductive and electromagnetic interference shielding applications.

The gene responsible for encoding SERT has a functional polymorphism at the 5′-regulatory promoter region, which results in two forms, long (L) and short (S). The LL-genotype is hypothesized to play a key role in the early onset of alcohol use. The present invention discloses the differences in treatment and diagnosis based on the L or short genotypes as well as on a single nucleotide polymorphism of the SERT gene, the 3′ UTR SNP rs 1042173. The present invention demonstrates the efficacy of using the drug ondansetron and similar drugs for treatment based on variations in the polymorphisms of the SERT gene as well as methods for diagnosing susceptibility to abuse of alcohol and other addiction-related diseases and disorders.

The present invention provides for compositions and methods for treating or preventing addictive and compulsive diseases and disorders, particular alcohol-related diseases and disorders, disclosed herein. The GLP activators of the present invention are effective against various alcohol and drug dependency diseases. In accordance with the invention, the present compositions and methods can be used to intercede upstream or downstream in the signal transduction cascade involved in GLP action to treat various alcohol and drug dependency diseases. In one embodiment, the synthesis or release of endogenous GLP can be stimulated. In another embodiment, the endogenous synthesis or release of another molecule active in the cascade downstream from GLP, (e.g., a molecule produced in response to GLP binding to a receptor), can be stimulated. Accordingly, the methods and compositions of the invention are useful for preventing, treating, diagnosing, or monitoring the progression various alcohol and drug dependency diseases disclosed herein.

The present invention relates to a trehalulose-containing composition, its preparation and use.

A garment/device/support system, system and method for a wheelchair bound person includes one or two sleeves that are worn on the arms. The sleeves are connected by straps to a chassis or vest worn on the torso. The straps are affixed using Velcro or other fasteners that transfer motion of the wearer's arms to the chassis or vest. Motion, energy and stimulation are transferred to muscle groups, viscera, organs, and body parts in other parts of the body through the motion of the arms as the user moves about in the wheelchair. A cape may be affixed to the vest including shoulder straps connected to a center back portion and extending to a lower portion for positioning beneath and/or attaching to the user's hips or legs. A seat cushion and belt may be provided.

A composition includes a salt of a carboxyethyl phosphinate ester compound. Additionally, the composition may also include a polymeric resin, such as a thermoplastic resin. The composition may have improved physical and chemical properties including flame retardancy, thermal stability, and hygroscopicity.

The invention relates to a silica glass compound having improved physical and chemical properties. In one embodiment, the present invention relates to a silica glass having a desirable brittleness in combination with a desirable density while still yielding a glass composition having a desired hardness and desired strength relative to other glasses. In another embodiment, the present invention relates to a silica glass composition that contains at least about 85 mole percent silicon dioxide and up to about 15 mole percent of one or more dopants selected from F, B, N, Al, Ge, one or more alkali metals (e.g., Li, Na, K, etc.), one or more alkaline earth metals (e.g., Mg, Ca, Sr, Ba, etc.), one or more transition metals (e.g., Ti, Zn, Y, Zr, Hf, etc.), one or more lanthanides (e.g., Ce, etc.), or combinations of any two or more thereof.

Materials for, and methods of, colorizing a metallic surface with micro-gratings using vibration cutting technologies are provided. Micro-gratings on aluminum, brass, and stainless steel surfaces can be rapidly created to effect, under illumination, at least one color observable in the visible spectrum using elliptical vibration texturing, a vibration-assisted mechanical cutting process. The modified metallic surface can display multiple visible colors, an iridescent effect caused by changes in one or more cutting parameters employed to produce the micro-gratings, the angle of illumination by an incident light, and/or the viewing angle of the surface under illumination.

The invention discloses a medicinal composition for treating hemophilia. The medicinal composition for treating the hemophilia is prepared from the following raw materials in part by weight: 15 to 30 parts of rehmannia root, 15 to 25 parts of yerbadetajo herb, 10 to 15 parts of south dodder seed, 10 to 15 parts of Indian buead, 5 to 8 parts of glossy privet fruit, 5 to 8 parts of prepared tuber fleeceflower root, 5 to 10 parts of twotooth achyranthes root, 10 to 15 parts of hairyvein agrimonia herb and bud and 3 to 6 parts of rehmannia root. The medicinal composition for treating the hemophilia can cool the blood and stop bleeding, can also generate and enrich the blood, treats both the symptoms and diseases, has a two-way adjustment function and a good curative effect on the hemophilia and various hemorrhagic diseases caused by blood heat, can stop bleeding quickly, and obviously increases the average value of procoagulant activity.

A method for formulating a cationic and non-ionic oil in water emulsion, preferably in a cream form, containing growth factors, preferably platelet derived growth factors, specific matrikine peptides, botanicals, emollients, nano-molecules, antioxidants, antiseptics, neuro-peptides, anti-dermatophytics, polysaccharides, sensorial peptides, osmotically driven moisturizers, and siloxane barriers. For application to the feet and other affected parts of the body for the relief of diabetic skin and tissue trauma.

An alloy s provided for dental prostheses including porcelain fused to metal (PFM) restorations. The alloy is grey in color with an oxide coating for bonding porcelain to the oxidized cast alloy substrate. The alloy has suitable mechanical properties for cast prostheses and for the support of the porcelain and is readily polished to a bright sheen. The alloy is based on a palladium-cobalt binary system, has a coefficient of thermal expansion (CTE) in the range of about 14.0 to 15.3 and may include one or more of the following additive metals: aluminum, boron, chromium, gallium, lithium, rhenium, ruthenium, silicon, tantalum, titanium, and tungsten.

The invention provides low-dust animal litters made from one or more ingredients that function as an animal litter and one or more polyols that function to control dust in the litter. The low-dust animal litters are made by selecting one or more litter ingredients suitable for making an animal litter and combining the litter ingredients with one or more polyols, generally by applying the polyols to the surface of one or more ingredients before or during the process of combining the ingredients to produce the litter.

A kit containing a plurality of scent/flavor samples and taste samples contained in individual vessels. Methods of teaching an understanding of taste, smelling with the nose, smelling with the mouth, and the concept of “flavor,” is facilitated. Numerous possibilities of combining scents with tastes, thus enabling a person to explore creatively and deductively the creation of new scent and flavor mixtures, as well as learning what makes familiar flavors taste the way they do.

The invention is an integrally blow-moulded bag-in-container obtainable by blow-moulding an injection moulded multi-layer preform. The bag-in-container includes an inner layer forming the bag and an outer layer forming the container, and a single opening, the mouth, fluidly connecting the volume defined by the bag to the atmosphere. The container further includes at least one interface vent fluidly connecting the interface between inner and outer layers to the atmosphere, wherein the bag is anchored to the outer layer at at least one point remote from the single opening and interface vent. The invention also relates to a process and a mould for the production of the blow-moulded bag-in-container.

A method for preparing an organic complex microelement fertilizer for engineering wound soil remediation includes compounding chitosan oligosaccharide or/and earthworm dung or/and silkworm sand, water or/and hydrogen peroxide, an organic complex trace element solution, polyethylene glycol octyl phenyl ether, and polysorbate under certain conditions. The present invention can significantly improve physical and chemical properties of engineering wounds, enhance effectiveness of trace elements in soil, and prevent plant physiological diseases due to lack of trace elements, and promote plant growth and development.

A semiconductor device having improved physical and electrical properties includes a semiconductor chip comprising a first semiconductor substrate and a second semiconductor substrate on the first semiconductor substrate, conductive lines embedded in the first semiconductor substrate to be exposed on a surface of the first semiconductor substrate, a circuit structure formed on the second semiconductor substrate, and an external terminal formed on the circuit structure and electrically connected to the circuit structure, and an exposed surface of the first semiconductor substrate, where exposed surfaces of the conductive lines are located at the same plane.

The synthesis method of green vitamins is a synthesis method of natural vitamins. The invention provides a synthesis method of green vitamins. The product of the invention comprises the following raw materials by weight: 30-50g of kelp, 40-50g of sesame, 30-40g of porphyra, 30-50g of white fungus, 30-40g of sunflower seed, 30-40g of black fungus and 20-40g of endothelium corneum.

A composition and method for producing an organic material with an inorganic coating. The inorganic coating may include ammonium sulfate. The present disclosure also provides a fertilizer having an inorganic coating. A method according to the present disclosure includes granulating an organic material and coating the organic material with a reactive coating composition. The inorganic coating material may be generated in situ to the process of coating the organic material.