433results about How to "Improve curing" patented technology

A system for repairing an intervertebral disc by delivering and curing a biomaterial in situ within the disc. The system includes both a device, having an insertable balloon and related lumen, controls and adapters, as well as an in situ curable biomaterial (and related biomaterial delivery means). The system can allow the doctor to determine a suitable endpoint for biomaterial delivery, by controlling distraction and / or biomaterial delivery pressure, and in turn, to deliver a desired quantity of biomaterial to the balloon in order to achieve improved polymer cure and implant characteristics. Also provided is a related method for repairing an intervertebral disc by using such a system to deliver and cure the biomaterial in situ. The system can be used to implant a prosthetic total disc, or a prosthetic disc nucleus in a manner that leaves the surrounding disc tissue substantially intact.

A system for treating an abnormal vertebral body such as a compression fracture. In an exemplary embodiment, the system includes a biocompatible flow-through implant structure configured with a three-dimensional interior web that defines flow openings therein for cooperating with a two-part hardenable bone cement. The flow-through structure is capable of compacted and extended shapes and in one embodiment provides a gradient in flow openings for controlling flow parameters of a bone cement injected under high pressure into the interior thereof. The flow-through implant structure is configured for transducing cement injection forces into a selected direction for moving apart cortical endplates of a vertebra to reduce a fracture. In one embodiment, the flow-through implant structure is coupled to an Rf source for applying Rf energy to a two-part bone cement to accelerate curing of the cement to thereby allow on-demand alterations of cement viscosity. The Rf system allows for control of bone cement polymerization globally or regionally to prevent cement extravasion and to direct forces applied to a vertebra to reduce a fracture.

A system for repairing an intervertebral disc by delivering and curing a biomaterial in situ within the disc. The system includes both a device, having an insertable balloon and related lumen, controls and adapters, as well as an in situ curable biomaterial (and related biomaterial delivery means). The system can allow the doctor to determine a suitable endpoint for biomaterial delivery, by controlling distraction and / or biomaterial delivery pressure, and in turn, to deliver a desired quantity of biomaterial to the balloon in order to achieve improved polymer cure and implant characteristics. Also provided is a related method for repairing an intervertebral disc by using such a system to deliver and cure the biomaterial in situ. The system can be used to implant a prosthetic total disc, or a prosthetic disc nucleus in a manner that leaves the surrounding disc tissue substantially intact.

A method of forming a three-dimensional object is carried out by providing a carrier and an optically transparent member having a build surface, the carrier and the build surface defining a build region therebetween; filling the build region with a polymerizable liquid; irradiating the build region through the optically transparent member to form a solid polymer from the polymerizable liquid and advancing the carrier away from the build surface to form the three-dimensional object from the solid polymer, while also concurrently with the irradiating and / or advancing steps: (i) continuously maintaining a dead zone of polymerizable liquid in contact with the build surface, and (ii) continuously maintaining a gradient of polymerization zone between the dead zone and the solid polymer and in contact with each thereof. The gradient of polymerization zone comprises the polymerizable liquid in partially cured form (e.g., so that the formation of fault or cleavage lines between layers of solid polymer in the three-dimensional object is reduced). Apparatus for carrying out the method is also described.

A method of forming a three-dimensional object is carried out by providing a carrier and an optically transparent member having a build surface, the carrier and the build surface defining a build region therebetween; filling the build region with a polymerizable liquid; irradiating the build region through the optically transparent member to form a solid polymer from the polymerizable liquid and advancing the carrier away from the build surface to form the three-dimensional object from the solid polymer, while also concurrently with the irradiating and / or advancing steps: (i) continuously maintaining a dead zone of polymerizable liquid in contact with the build surface, and (ii) continuously maintaining a gradient of polymerization zone between the dead zone and the solid polymer and in contact with each thereof. The gradient of polymerization zone comprises the polymerizable liquid in partially cured form (e.g., so that the formation of fault or cleavage lines between layers of solid polymer in the three-dimensional object is reduced). Apparatus for carrying out the method is also described.

This invention relates to compositions useful as adhesives and more particularly to the preparation of heat-cured epoxy-based adhesive compositions with improved impact resistance and good adhesion to oily metal substrates.

This invention concerns a method for the preparation of polyurea elastomers, comprising: (a) reacting an amine chain extender with dialkyl maleate to form an aspartic ester, wherein the chain extender has a molar amount of amine groups that is less than the moles of dialkyl maleate; (b) blending the aspartic ester with one or more polyoxyalkyleneamines to prepare a resin blend; (c) contacting the resin blend with an isocyanate under conditions effective to form a polyurea elastomer. This invention also concerns a a polyurea elastomer, comprising the reaction product of (a) a resin blend containing one or more polyoxyalkyleneamine and an aspartic ester and (b) an isocyanate, wherein the aspartic ester in the resin blend comprises a reaction product of an amine chain extender and a dialkyl maleate, wherein the mole ratio of amine functionality in the amine chain extender to dialkyl maleate or fumarate is greater than 1:1.

In one embodiment the invention is An adhesive composition comprisinga) a polymer having a flexible backbone and a reactive moiety capable of cross-linking,b) a particle comprising an active agent encapsulated in an encapsulating agent wherein the active agent comprises a catalyst for cross-linking of the reactive moiety, a curing agent for the reactive moiety, an accelerator for the curing reaction or a mixture thereof; and the encapsulating agent comprises a side chain crystallizable polymer wherein the active agent is not substantially extractable from the particle at ambient conditions in a first extraction after particle formation.This composition is used in binding two subtracters together.

An apparatus and process for curing UV-curable inks is provided comprising multiple printhead ejectors and ultraviolet light emitting diodes (UV-LEDs). The printhead ejectors are placed on the assembly in a geometry corresponding to the UV-LEDs such that when a printhead ejector deposits an ink droplet upon a substrate moving relative to the assembly, at least one UV-LED can pass directly over the ink droplet.

A free radical curable liquid for inkjet printing of food packaging materials includes no initiator or otherwise one or more initiators selected from the group consisting of non-polymeric di- or multifunctional initiators, oligomeric initiators, polymeric initiators, and polymerizable initiators; and a polymerizable composition of the liquid consists essentially of: a) 25-100 wt % of one or more polymerizable compounds A having at least one acrylate group G1 and at least one second ethylenically unsaturated polymerizable functional group G2 selected from the group consisting of a vinlyether group, an allylether group, and a allylester group; b) 0-55 wt % of one or more polymerizable compounds B selected from the group consisting of monofunctional acrylates and difunctional acrylates; and c) 0-55 wt % of one or more polymerizable compounds C selected from the group consisting of trifunctional acrylates, tetrafunctional acrylates, pentafunctional acrylates and hexafunctional acrylates. If the weight percentage of compounds B>24 wt %, then the weight percentage of compounds C>1 wt %, and all weight percentages of A, B, and C are based upon the total weight of the polymerizable composition. At least one polymerizable compound B or C is present in the polymerizable composition if the free radical curable liquid contains no initiator.

The invention features a photopolymerizable composition that comprises a cationically polymerizable resin, and a photoinitiator system comprising an iodonium salt, a visible light sensitizer, and one or more anthracene-based compounds as electron donors. Electron donor combinations used in the invention include multiple substituted anthracene compounds or a combination of at least one substituted anthracene compound with unsubstituted anthracene.

A special method is provided for more uniformly and quickly curing products with a scratch-resistant UV curable coating or UV curable printing thereon with high intensity UV light, such as for wires, cables, tubes, tubing, hoses, pipes, CDs, DVDs, golf balls, golf tees, eye glass lenses, contact lenses, string instruments, decorative labels, peelable labels, peelable stamps, doors, countertops, etc. The method can also be operated with one or more special UV curing apparatus equipped with a controller and one or more super high power UV-LED modules.

This invention relates to the use of tumor-derived or associated extracellular ribonucleic acid (RNA) found circulating in the plasma or serum fraction of blood for the detection, monitoring, or evaluation of cancer or premalignant conditions. Extracellular RNA may circulate as non-bound RNA, protein-bound RNA, lipid-RNA complexes, lipoprotein (proteolipid)-RNA complexes, protein-RNA complexes including within or in association with ribonucleoprotein complexes, nucleosomes, or within apoptotic bodies. Any intracellular RNA found in plasma or serum can additionally be detected by this invention. Specifically, this invention enables the extraction of circulating RNA from plasma or serum and utilizes nucleic acid amplification assays for the identification, detection, inference, monitoring, or evaluation of any neoplasm, benign, premalignant, or malignant, in humans or other animals, which might be associated with that RNA. Further, this invention allows the qualitative or quantitative detection of tumor-derived or associated extracellular RNA circulating in the plasma or serum of humans or animals with or without any prior knowledge of the presence of cancer or premalignant tissue.

A curable organopolysiloxane resin composition having a viscosity at 25° C. in the range of 0.001 to 5,000 Pa·s, a total acid number as specified by JIS K 2501 (1992) in the range of 0.0001 to 0.2 mg / g, and light transmittance in a cured state equal to or greater than 80%; an optical part comprised of a cured body of the aforementioned composition. The curable organopolysiloxane resin composition of the invention is characterized by good transparency, low decrease in transmittance when exposed to high temperatures, and excellent adhesion when required.

The invention relates to the preparation of a silica reinforced rubber composition where alkoxysilane and / or sulfur cure reactions within the elastomer host are controlled by the use of a selected amino acid, or amino acid-containing protein based, activator. The invention also relates to such composite and to a tire having at least one component of such composite

The present invention is directed to nano-composite and composition comprising a cationic mediator and method thereof. The cationic mediator is comprised of a hydrophobic unit and a heterocyclic cationic unit. The nano-composite is practically useful in formulating compositions such as rubber and tire products with improved gas permeability, cure properties, and / or mechanical properties etc.

A process is provided for producing fast curing bonded with phenolic resin, which comprises pulverulent phenolic resins mixed with or applied to the substrate to be adhered together with pulverulent addition polymers selected from the group consisting of polyvinyl alcohols and addition polymers, stabilized by hydroxyl-containing protective colloids of at least one monomer selected from the group consisting of the vinyl esters of branched or unbranched carboxylic acids of 1 to 12 carbon atoms, the esters of acrylic acid and methacrylic acid with branched or unbranched alcohols of 1 to 12 carbon atoms, vinylaromatics, vinyl halides, olefins and dienes, and subsequently, by the employment of elevated temperature and optionally elevated pressure, cured and processed into a shaped article.

A method of producing a flexographic printing plate, comprises:a) inkjet printing a layer of flexographic material in a predetermined pattern onto a substrate;b) partially curing at least part of the printed layer of flexographic material so as to immobilize it on the substrate; andc) repeating steps (a) and (b) so as to print and partially cure one or more further layers of flexographic material in the predetermined pattern on the previous layer(s),characterized by additionally curing one or more lower printed layers before or while printing one or more upper layers so as to reduce spreading of the lower printed layer(s).

A method of forming a three-dimensional object useful as a casting mold is carried out by providing a carrier and an optically transparent member having a build surface, the carrier and the build surface defining a build region therebetween; filling the build region with a liquid photocurable ceramic resin; irradiating the build region through the optically transparent member to form a solid polymer from the polymerizable liquid and advancing the carrier away from the build surface to form the three-dimensional object from the solid polymer, while also concurrently with the irradiating and / or advancing steps: (i) continuously maintaining a dead zone of polymerizable liquid in contact with the build surface, and (ii) continuously maintaining a gradient of polymerization zone between the dead zone and the solid polymer and in contact with each thereof. The gradient of polymerization zone comprises the polymerizable liquid in partially cured form (e.g., so that the formation of fault or cleavage lines between layers of solid polymer in the three-dimensional object is reduced). Apparatus for carrying out the method is also described.

The curing rate of a two component laminating adhesive is effectively accelerated by incorporating in at least one component a microencapsulated catalyst. When the laminating adhesive is subjected to an effective amount of pressure (for example, the pressure applied when laminating flexible films together using nip rollers), the catalyst (which may be, for example, a dialkyl tin dicarboxylate) is released from encapsulation and is made available to catalyze the polyurethane-forming reaction between the isocyanate groups and the active hydrogen-functionalized groups in the adhesive mixture.

The invention provides in one form a macromonomer comprising a polysiloxane copolymer having a backbone structure derived from siloxane monomer units that are substituted or unsubstituted arylsiloxanes, arylalkylsiloxanes, alky(alkyl)siloxanes of the general formula —R1R2SiO— and wherein the terminal groups of the copolymer backbone include crosslinkable groups and wherein pendent from the backbone are at least two crosslinkable groups. The macromonomer may be cured in vivo by ultraviolet or visible light. The invention includes intraocular lenses formed by such macromonomers.

An epoxy composition for applications such as one-part adhesives, coatings, prepreg and molding compounds that includes leuco dyes, particularly those comprising a N,N-dialkylamino-, N,N-diarylamino-, or cycloalkylamino-functional group on one of the aromatic rings, as a co-catalyst or co-curing agent. The use of the leuco dye co-catalyst provides improved curing speed of the epoxy composition comprising a latent curing agent / catalyst such as Novacure imidazole microcapsules while maintaining the shelf-life stability. The epoxy may also include a secondary co-catalyst that includes amides and lactams, particularly those comprising a N,N-dialkylamino-, N,N-diarylamino-, or dicycloalkylamino-functional group. Secondary cocatalysts of low mobility at the storage conditions, such as those with a long chain substitutent, dimeric or oligomeric amides or lactams, are particularly preferred. The improved epoxy composition is implemented as adhesives for manufacturing an anisotropic conductive film (ACF) and also for connecting, encapsulating, or packaging of electronic devices.

The invention features a photopolymerizable composition that comprises a cationically polymerizable resin, and a photoinitiator system comprising an iodonium salt, a visible light sensitizer, and one or more anthracene-based compounds as electron donors. Electron donor combinations used in the invention include multiple substituted anthracene compounds or a combination of at least one substituted anthracene compound with unsubstituted anthracene.

The invention relates to a process for the manufacture of a waterborne multistage polymer dispersion that has ethylenically unsaturated functional groups for crosslinking. The process comprises the steps of;a. making an aqueous emulsion or solution of a first stage polymer comprising carboxylic acid functionalised monomers to an amount sufficient to make the first stage polymer water soluble or dispersible,b. at least partially neutralising the first stage polymer with a base,c. forming a two-stage polymer dispersion by adding to the at least partially neutralised first stage polymer a second stage monomer mixture and emulsion polymerising said second stage monomer mixture to a second stage polymer which is less hydrophilic than the first stage polymer,d. reacting with the obtained two-stage polymer dispersion a bi-functional compound comprising an ethylenically unsaturated group and a group reactive towards the carboxylic acid in the two-stage polymer.The invention further relates to a water-borne curable multistage polymer dispersion, to coating compositions.

A method for the production of bristles structures on an arbitrary kind of carrier using a mold tool is described having channels extending from channel walls for shaping bristles, wherein a mold mass for forming the bristles is introduced under pressure into the channels, preferentially using the injection molding technique. Towards this end, the carrier is disposed directly or indirectly onto the mold walls of the channels in such a fashion that the free cross-section of the channels is completely covered and the mold mass is subsequently introduced onto the carrier with a sufficient mold pressure (injection pressure) that the carrier is broken-through in the vicinity of the free cross-section of the channels thereby displacing the carrier material, with the carrier mass subsequently filling the channels.

The present invention includes a method of utilizing four peptide hormones to inhibit the growth of cancer(s). A dramatic decrease in the number of human pancreatic adenocarcinoma cells (i.e., the type of cancer with the highest mortality, with patients only surviving four months) was observed responsive to treatment. The application of the invention would be to utilize one or more of these peptide hormones alone and / or in combination to treat cancer. The ability of these peptide hormones to decrease the number of adenocarcinoma cells has implications for adenocarcinomas at other sites in the body with the majority of cancers of the breast, colon and prostate also being adenocarcinomas. Adenocarcinomas also occur in the lung and other tissues. Treatment of a wide variety of cancers in addition to adenocarcinomas is anticipated by the present invention.

The invention relates to a preparation method of monodisperse polylactic acid (PLA) microballoon spheres, which includes: (1) the PLA is dissolved in methylene dichloride so as to be taken as a dispersed phase and polyvinyl alcohol is dissolved in water so as to be used as a continuous phase; (2) two solutions are respectively put into injectors and the injectors are arranged on two boost pumps and connected with a microchannel reactor, and then the flow velocities of the dispersed phase and the continuous phase are adjusted to ensure that liquid drops with uniform size are continuously generated at the joint of the two phases; (3) the generated liquid drops are collected in the aqueous solution of the polyvinyl alcohol and a variable frequency oscillator is adopted to assist the volatilization of a solvent so as to ensure that the liquid drops are solidified to spheres; and (4) the spheres are washed by ionized water for a plurality of times and arranged in an oven for drying to obtain the monodisperse PLA microballoon spheres. The monodisperse PLA microballoon spheres prepared by the invention have a smooth surface and a particle size ranging from 200 Mum to 1000 Mum; a reaction device has simple and easy preparation process and controllable dimension of microchannels. The size of the prepared microballoon spheres can be conveniently adjusted and controlled and the variable frequency oscillator is adopted for quickening the solidification process of the PLA microballoon spheres, with low cost and less time consumption.

An apparatus and process for curing UV-curable inks having multiple printhead ejectors and ultraviolet light emitting diodes (UV-LEDs). The printhead ejectors are placed on the assembly in a geometry corresponding to the UV-LEDs such that when a printhead ejector deposits an ink droplet upon a substrate moving relative to the assembly, at least one UV-LED can pass directly over the ink droplet.

The invention provides in one form a macromonomer comprising a polysiloxane copolymer having a backbone structure derived from siloxane monomer units that are substituted or unsubstituted arylsiloxanes, arylalkylsiloxanes, alky(alkyl)siloxanes of the general formula —R1R2SiO— and wherein the terminal groups of the copolymer backbone include crosslinkable groups and wherein pendent from the backbone are at least two crosslinkable groups. The macromonomer may be cured in vivo by ultraviolet or visible light. The invention includes intraocular lenses formed by such macromonomers.