46 results about "Bitter orange extract" patented technology

The invention discloses a method for extracting high-purity neohesperidin from an immature bitter orange. The method comprises the following steps: (1) crushing and impregnating an immature bitter orange raw material in water, adding a compound plant-hydrolase preparation, and performing enzymatic decomposition to obtain an enzymatically decomposed immature bitter orange; (2) performing heating extraction, cooling, centrifugation and filtration on the enzymatically decomposed immature bitter orange to obtain enzymatic immature bitter orange extract; (3) performing water bath heat preservation on the enzymatic immature bitter orange extract, adding a flocculating agent for flocculation treatment, and performing centrifugation and filtration to obtain immature bitter orange flocculation liquid; (4) performing nanofiltration, concentration and vacuum drying on the immature bitter orange flocculation liquid to obtain a neohesperidin crude product; (5) completely dissolving the neohesperidin crude product in an ethanol solution, performing strict filtration, and repeatedly performing cooling crystallization, washing and vacuum drying to obtain a high-purity neohesperidin product. The purity of the product obtained by the method can reach 98.6 percent, and the final yield is more than 90 percent; the method is simple in process, high in operability, low in energy consumption and cost, suitable for industrial production, small in ethanol residue amount, environment-friendly and safe.

The invention provides application of immature bitter orange or immature bitter orange extract to preparation of medicaments for treating irritable bowel syndrome. The invention also provides a medicinal composition based on the immature bitter orange or immature bitter orange extract. By improving bowel sensitivity and reducing colon frequency, peak potential, peak-to-peak value and peak area, the immature bitter orange extract therefore has an obvious curative effect in a treatment period of the irritable bowel syndrome, the belly ache caused by the irritable bowel syndrome can be suppressed, the phenomenon of colon dysfunction is improved, and a new choice is provided for clinical medication.

The invention relates to the field of plant extraction, and especially relates to an immature bitter orange extract product, a preparation method and an application of the immature bitter orange extract product for delaying skin aging. The provided extraction method improves the extraction technological parameters, aiming at the anti-aging effect. The obtained immature bitter orange extract product can obviously reduce the injury of ultraviolet ray on fibroblast and keratinocyte, the expression of type I collagen in fibroblast can be promoted, the expression of MMP-1 is inhibited, and efficacy for delaying skin aging can be performed. The immature bitter orange extract product can reach a purpose of delaying skin aging from epidermis and dermis, and research insufficiency of health care efficacy of the immature bitter oranges can be made up. The immature bitter orange extract product provides powerful support for development of anti-aging food, health products and cosmetics.

The invention relates to a general flavone extractive of an immature bitter orange or a bitter orange. The general flavone extractive is extracted through the following steps: cutting the immature bitter orange or the bitter orange into decoction pieces or smashing the immature bitter orange or the bitter orange, adding 4 to 15 times of water, decocting 1 to 3 times (1 to 3 hours each time), merging the decoction liquids, filtering through processed non-polar big hole resin, eluting by water and alcohol of which the concentration is lower than 20 percent sequentially to remove impurities, eluting by alcohol of which the concentration ranges from 25 to 90 percent and sodium hydrate of which the concentration ranges from 0.5 to 2 percent, collecting alcohol eluant, depressuring and concentrating to obtain a liquid extract of which the relative density is 1.20 to 1.40 (under the temperature ranging from 50 DEG C to 70 DEG C), depressuring and drying under the temperature ranging from 60 DEG C to 80 DEG C, and smashing to obtain the general flavone extractive of the immature bitter orange or the bitter orange. The extractive can be used for preparing medicines used for curing gastrointestinal dyskinesia-type functional indigestion, epigastralgia, abdominal distention, asitia, eructation, nausea, and vomit caused by chemotherapeutics and other reasons, and is prepared into dosage forms acceptable for pharmacology.

The invention relates to fish feed premixes and in particular to a premix for preventing irritation gill damage of trachinotus ovatus as well as a preparation method and application of the premix. The premix is prepared from the following components in parts by weight: 5-10 parts of a motherwort extract, 15-35 parts of a bitter orange extract, 10-15 parts of a plantain herb extract and 0.1-0.5 part of composite synergism substances, wherein the composite synergism substances comprise mint leaf powder, calcium chloride, citric acid and gallnuts at a weight ratio of (100-130):(1-1.5):(1-2.5):(10-18). Compared with a nutrient premix used in a trachinotus ovatus feed, the premix has a remarkable prevention function on irritation gill damage of the trachinotus ovatus, is capable of effectively alleviating symptoms of irritation gill damage of the trachinotus ovatus and effectively reducing the death rate caused by irritation gill damage of the trachinotus ovatus as multiple active factors are obtained through a unique fermentation technique and the composite synergism substances are compounded to synergistically improve prevention effects.

The invention discloses application of a water extract or alcohol extract of Chinese medicinal herb immature bitter orange to the preparation of a weight-reducing and lipid-lowering medicament or the preparation of a medicament having a lipase activity suppressing effect. According to the invention, the defects of low efficiency and large side effect of the conventional clinical weight-reducing medicament, in particular traditional Chinese medicines are overcome, and a weight-reducing and lipid-lowering medicament with a definite mechanism, a scientific target point, a small side effect and high clinical effective rate is provided.

The invention discloses an immature bitter orange extract, a preparation and an application, belongs to the field of a traditional Chinese medicine, and particularly relates to an immature bitter orange extract and a medicinal preparation containing the extract. The immature bitter orange extract can be used for preparing a medicine for preventing or treating obesity. The immature bitter orange extract, which is obtained by adding a small amount of rhizoma anemarrhenae medicinal material into an immature bitter orange medicinal material, has a significant effect of treating the obesity, and has an unexpected effect in comparison with a single immature bitter orange extracting method. Based on the sufficient and reasonable design, the immature bitter orange extract with a significant effect can be obtained by extracting, denominating and enriching ethanol water with proper concentration.

The invention provides an air freshener applicable to north houses. The paste-type air freshener comprises a first layer, a second layer, a third layer, a fourth layer and a fifth layer from top to bottom, wherein the first layer is prepared from a pistacia weinmannifolia leaf extract, a fingered citron leaf extract, kumquat juice and jasmine essential oil; the second layer is prepared from beewax, a spirulina extract, a needle mushroom extract, a dandelion achene extract, a ginkgo leaf extract, a black bean extract, an immature bitter orange extract and pachyman; the third layer is prepared from hyaluronic acid, a herba meconopsis extract, a betel nut extract, a grape seed extract, a mentha longifolia extract and a myristica fragrans extract; the fourth layer is prepared from locust bean gum, a grape skin extract, theobromine, a herba schizonepetae extract and bitter orange leaf essential oil; and the fifth layer is prepared from aerogel, lavender essential oil, myrtle essential oil and a radix polygalae extract.

The invention discloses an extraction method of an immature bitter orange extract. The extract comprises pectin, synephrine, hesperidin, total flavonoids of immature bitter oranges, plant fibers and the like. The extraction method comprises the steps: selecting an immature bitter orange raw material with a diameter of less than 1.5 cm; extracting with a hydrochloric acid solution to obtain a mixture of pectin and synephrine, and further separating and purifying to obtain pectin and synephrine products; extracting with a sodium carbonate solution to obtain an immature bitter orange total flavone product; extracting with sodium hydroxide to obtain a hesperidin product; and the finally extracted residues are pure plant fibers. Various products are comprehensively developed from immature bitter oranges by using various methods, and the complete utilization of materials is ensured so that the production cost is reduced, and the environmental pollution is reduced.

The invention relates to a cataplasm for curing acute injury of soft tissues and a preparation method thereof. The cataplasm is prepared by raw materials of angelica extract, saposhnikoviae radix extract, bitter orange extract, anemarrhena asphodeloides extract, rhizoma arisaematis (processed) extract, fructus trichosanthis extract, angelica dahurica extract, carthamus tinctorius extract, thunberg fritillary bulb extract and suitable accessories. The cataplasm consists of rear lining layers, ointments containing drugs, and cover lining layers. The cataplasm takes effect quickly, performances of moisture and air permeability are good, usage is comfortable and convenient, irritation on skins is small, and compliance of patients is high.

The invention relates to a traditional Chinese medicine for treating ulcers and a preparation method of the traditional Chinese medicine and belongs to the technical field of traditional Chinese medicines. Herbal mouthwash for treating oral ulcer is prepared from raw materials in parts by weight as follows: 150-200 parts of watermelon juice, 35-50 parts of watermelon peel extract, 40-50 parts of carrot extract, 10-18 parts of Chinese yam extract, 8-15 parts of poria cocos extract, 5-10 parts of hematite extract, 6-12 parts of bitter orange extract, 3-5 parts of costustoot extract, 8-10 parts of mint extract, 0.2-0.9 parts of grape polyphenols, 0.3-0.7 parts of sorbitol and 5-8 parts of propolis. A user only needs to have the herbal mouthwash for treating oral ulcer in the mouth for 5-8 minutes each time and twice a day, and the effect of treating oral ulcer can be realized. The herbal mouthwash tastes a little sweet, has little bitterness, is convenient to take, does not have toxic or side effects, can quickly and efficiently treat erosive ulcer and can relieve pain.

The invention discloses a preparation method of a water-soluble immature bitter orange extract with bitterness removed. The method comprises steps as follows: step one, selecting an immature bitter orange extract containing 10% of synephrine, dissolving the immature bitter orange extract with 10 times of water, heating the solution to the temperature of 70 DEG C to prepare an immature bitter orange extract aqueous solution; step two, adding 1% of an aqueous solution of 5% of a clarifying agent ZTC-B of dry powder to the immature bitter orange extract aqueous solution in step one, performing stirring and heating for 10 min, and adding 1% of an aqueous solution of 5% of a clarifying agent ZTC-A of dry powder, and performing stirring and heating for 10 min; step three, subjecting a filtered filtrate to macroporous adsorption resin HPD-600 to adsorb flavonoid bitterness ingredients of the immature bitter orange extract until the effluent is free of bitterness to obtain the immature bitter orange extract with bitterness removed; step four, performing water elution on the resin column to obtain a water solution; step five, merging, concentrating and drying the water solution and the effluent to obtain the water-soluble immature bitter orange extract with bitterness removed finally. The method has very good technical effects.

The invention relates to a facial cleanser including a propolis extract, an aesculus hippocastanum extract, a bitter orange extract, tocopherol, a surfactant, a foam stabilizer, an emulsifier, a foaming agent, a thickener and deionized water. The invention also discloses a preparation method of the facial cleanser. By adding the propolis extract, aesculus hippocastanum extract, bitter orange extract and tocopherol, the facial cleanser is capable of increasing the anti-oxidation effect of cells and improving the self-healing ability of skin, has the anti-inflammatory and soothing functions, andcan promote the effective ingredients to play a role; the formula is stable, and all the components have the synergistic effect to produce the technical effect of mild and effective skin cleaning, skin soothing and low sensitization.

A technical solution adopted in the invention is a preparation process of a cordyceps militaris apple enzyme with a weight reducing effect. The process comprises the following steps: (1) preparing seed liquid of yeast; (2) preparing seed liquid of lactic acid bacteria; (3) performing fermentation cultivation; (4) performing centrifugal treatment to obtain a stock solution of enzyme; (5) adding a bitter orange extract in a mass ratio of 1:100 to the stock solution of enzyme, synanthrin in a mass ratio of 1:20 to the stock solution of enzyme, a ginger extract in a mass ratio of 1:100 to the stock solution of enzyme, potassium sorbate in a mass ratio of 1:2,000 to the stock solution of enzyme and a cordyceps militaris extract in a mass ratio of 1:10 to the stock solution of enzyme to the stock solution of enzyme; stirring uniformly; sterilizing for 30-50 minutes at high temperature of 115 DEG C; and then subpackaging.

The invention discloses a pharmaceutical composition for treating cardiovascular diseases and a preparation method thereof. The pharmaceutical composition comprises the following raw materials in parts by weight: 50-200 parts of a danshen root extract, 30-120 parts of panax notoginseng total saponins, 30-120 parts of a bitter orange extract, 30-200 parts of a Chinese angelica extract, 30-200 parts of a ginger extract, 5-40 parts of a Chinese angelica volatile oil inclusion compound and 5-40 parts of a ginger volatile oil inclusion compound. The preparation method comprises the following steps: preparing the danshen root extract, preparing the panax notoginseng total saponins, preparing the bitter orange extract, preparing the Chinese angelica and ginger extracts, preparing the Chinese angelica and ginger volatile oil inclusion compounds, and mixing the raw materials. The pharmaceutical composition disclosed by the invention has the positive effects that the active ingredients of each medicinal material are fully extracted and purified, the usage amount of a solvent is relatively small, the time is saved, and the production cost is reduced. The pharmaceutical composition can be used for effectively treating ischemic heart diseases of coronary heart disease, angina pectoris, miocardial infarction and the like, and also has the effect of reducing the blood pressure and blood fat.