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Cataplasm for curing acute injury of soft tissues and preparation method thereof

A technology of cataplasm and non-woven fabrics, applied in the field of pharmaceutical preparations, which can solve the problems of low bioavailability, poor patient compliance, and easy-to-contaminate clothing

Inactive Publication Date: 2012-07-18
WUXI JIMIN KEXIN SHANHE PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, as a drug for the treatment of acute soft tissue injuries, Sprain Gui Capsules has the common disadvantages of oral preparations-obvious first pass effect and low bioavailability, which to some extent limits the wide application of this drug in clinical practice
The commonly used liniment and medicinal wine in clinical treatment contain a large amount of ethanol, and those who are allergic to ethanol are prone to allergic reactions, and the use of these dosage forms is easy to contaminate clothes, and the patient's compliance is poor.

Method used

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  • Cataplasm for curing acute injury of soft tissues and preparation method thereof
  • Cataplasm for curing acute injury of soft tissues and preparation method thereof
  • Cataplasm for curing acute injury of soft tissues and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0088] Backing layer: non-woven fabric

[0089] Cover lining: polyester film

[0090] The composition of the medicated ointment layer is as follows by weight:

[0091]

[0092] Preparation method: crush the extract of traditional Chinese medicine, weigh gelatin and tragacanth gum according to the prescription, add water, heat in a water bath to dissolve, mix polyacrylic acid, glycerin and zinc oxide evenly, add to the above glue, stir and mix evenly, and then Adding polyethylene glycol-400 to disperse the suspension of the compound extract, and finally adding azone to obtain a paste. Then spread it evenly on the non-woven fabric, cover it with a polyester film, and cut it into a suitable size.

[0093] Wherein the preparation method of the Chinese medicine extract is: use 360g of Angelica sinensis, 320g of Fangfeng, 320g of Citrus aurantii, 320g of Anemarrhena, 320g of Arisa, 320g of Trichosanthes, 320g of Angelica dahurica, and 160g of safflower, which are properly pulve...

Embodiment 2

[0095] Backing layer: non-woven fabric

[0096] Cover lining: aluminum foil-polyethylene composite film

[0097] The composition of the medicated ointment layer is as follows by weight:

[0098]

[0099] Preparation method: crush the Chinese medicine extract, weigh gelatin, sodium polyacrylate, and polyvinyl alcohol according to the prescription, add water to make swelling, stir and mix evenly, mix azone, glycerin, and zinc oxide evenly, and add to the above swelling solution , stir and mix evenly, and then add the suspension of the compound extract dispersed with propylene glycol and azone to obtain a paste. Then spread it evenly on the non-woven fabric, cover it with aluminum foil-polyethylene composite film, and cut it into a suitable size.

[0100] Wherein the preparation method of Chinese medicine extract is identical with embodiment 1.

Embodiment 3

[0102] Backing layer: non-woven fabric

[0103] Lid liner: polyethylene film thin

[0104] The composition of the medicated ointment layer is as follows by weight:

[0105]

[0106]

[0107] Preparation method: Weigh polyacrylic acid sodium, carbomer, add water to make swelling according to the prescription amount, add aluminum trichloride, stir and mix evenly; mix glycerin and kaolin and add to the swelling solution; use propylene glycol to mix menthol and traditional Chinese medicine extracts Dissolve the powder into a suspension and add it; finally add citric acid, stir and mix evenly to obtain a paste. Then spread it evenly on the non-woven fabric, cover it with polyethylene film, and cut it into a suitable size.

[0108] Wherein the preparation method of the Chinese medicine extract is: use 360g of Angelica sinensis, 320g of Fangfeng, 320g of Fructus Aurantii, 320g of Anemarrhena, 320g of Arisa, 320g of Trichosanthes, 320g of Angelica dahurica, and 160g of safflow...

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Abstract

The invention relates to a cataplasm for curing acute injury of soft tissues and a preparation method thereof. The cataplasm is prepared by raw materials of angelica extract, saposhnikoviae radix extract, bitter orange extract, anemarrhena asphodeloides extract, rhizoma arisaematis (processed) extract, fructus trichosanthis extract, angelica dahurica extract, carthamus tinctorius extract, thunberg fritillary bulb extract and suitable accessories. The cataplasm consists of rear lining layers, ointments containing drugs, and cover lining layers. The cataplasm takes effect quickly, performances of moisture and air permeability are good, usage is comfortable and convenient, irritation on skins is small, and compliance of patients is high.

Description

Technical field: [0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a cataplasm for regulating qi, promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, and is used for acute injuries of soft tissues such as the chest, flanks, back and limbs. technical background: [0002] Sprain Gui Capsule is a medicine for regulating qi, promoting blood circulation and removing blood stasis, reducing swelling and relieving pain. Oral Chinese patent medicine for acute injury of soft tissues such as chest, flanks, back, limbs, etc. It is composed of 9 medicinal materials: Angelica, Fangfeng, Fructus Aurantii, Anemarrhena, Aracea (manufactured), Gualou, Angelica dahurica, Safflower, and Fritillaria The extract is made from raw materials and suitable auxiliary materials, and is currently available on the market. [0003] Catapult is an external dosage form that dissolves or mixes drugs in natural and s...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61K9/70A61P19/04A61P29/00
Inventor 闻侃陈祥洪
Owner WUXI JIMIN KEXIN SHANHE PHARMA
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