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Rice bran flavones-containing health care product capable of preventing depression

A rice bran flavonoid and anti-depressant technology, which is applied in the field of health care products, can solve the problems of single target and single ingredient, and achieve the effects of avoiding toxic and side effects, facilitating mass production, and low price

Inactive Publication Date: 2017-07-28
LIAONING UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But it is worth noting that although there are many research reports on the antidepressant effect of traditional Chinese medicine, most of the research focuses on the research of a single component and a single target, while traditional Chinese medicine has the characteristics of overall and synergistic effects, which means The form and pathway of action between the foundations need to be further explored and clarified, which is also worthy of in-depth research in the future

Method used

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  • Rice bran flavones-containing health care product capable of preventing depression
  • Rice bran flavones-containing health care product capable of preventing depression

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1 contains the antidepressant health product of rice bran flavone

[0024] (1) Preparation of rice bran flavonoids

[0025] The extraction steps of rice bran flavonoids are as follows:

[0026] 1) Cellulase enzymatic hydrolysis and extraction: the rice bran is removed from impurities, dried, pulverized by a pulverizer, and passed through a 60-mesh sieve to make rice bran powder. The ratio of solid to liquid is 1:30 by mass, the rice bran powder is dissolved in water, the amount of cellulase added is 150U / g, and hot water extraction is carried out, the temperature is controlled at 50°C, pH 5.0, the enzymatic hydrolysis time is 2h, 4000r / g min was centrifuged for 15 minutes, filtered to obtain the cellulase enzymatic hydrolysis extract for subsequent use, and the precipitate A continued to be extracted with ethanol;

[0027] 2) Ethanol-assisted extraction: The mass ratio of solid to liquid is 1:20, dissolve the precipitate A in ethanol, the volume fraction of...

Embodiment 2

[0055] Embodiment 2 contains the antidepressant health product of rice bran flavone

[0056] (one)-(six) with embodiment 1.

[0057] (7) Antidepressant health products containing rice bran flavonoids, which are composed of the following raw materials by weight percentage:

[0058] Rice Bran Flavonoids 70%, Magnolia Bark Extract 10%, Asparagus Extract 5%,

[0059] Cornus officinalis extract 5%, Panax notoginseng extract 5%, Citrus aurantium extract 5%.

Embodiment 3

[0060] Embodiment 3 contains the antidepressant health product of rice bran flavone

[0061] (one)-(six) with embodiment 1.

[0062] (7) Antidepressant health products containing rice bran flavonoids, which are composed of the following raw materials by weight percentage:

[0063] Rice Bran Flavonoids 50%, Magnolia Bark Extract 10%, Asparagus Extract 10%,

[0064] Cornus officinalis extract 10%, Panax notoginseng extract 10%, Citrus aurantium extract 10%.

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Abstract

The invention discloses a rice bran flavones-containing health care product capable of preventing depression. The rice bran flavones-containing health care product capable of preventing depression is composed of, by weight, 50 to 70% of rice bran flavones, 5 to 10% of a magnolia cortex extract, 5 to 10% of a radix asparagi extract, 5 to 10% of a cornus officinalis extract, 5 to 10% of a pseudo-ginseng extract, and 5 to 10% of an immature bitter orange extract. According to the rice bran flavones-containing health care product, rice bran flavones are taken as the key functional raw materials used for preventing depression, compatibility of medicines is reasonable, the flavones and Chinese herbal medicines mixed health care product capable of preventing depression is formed. It is found in in vitro depression model cell experiments that the rice bran flavones-containing health care product possesses excellent protection effect on cells, and is capable of treating depression with excellent effect; toxic or side effect caused by chemical compounds is avoided; cost is low; the raw materials are widely available; and the rice bran flavones-containing health care product attracts a wide spread attention.

Description

technical field [0001] The invention belongs to the field of health products, in particular to an antidepressant health product containing rice bran flavonoids. Background technique [0002] Depression is a serious mood disorder. At present, about 350 million people in the world suffer from depression, the incidence rate in Sweden is 6.16%, in the United States is 4.45%, and in China is 3.02%. Depression seriously plagues the life and work of patients, and brings a heavy burden to families and society. About 15% of patients with depression die by suicide. A joint study by the World Health Organization, the World Bank and Harvard University shows that depression has become the second largest disease burden in China. The types and mechanisms of antidepressant medicines currently on the market are limited, and all of them have certain shortcomings, such as side effects, which threaten the health of other body functions of patients while treating depression, or slow onset and ...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P25/24A23L33/105
CPCA23V2002/00A61K36/258A61K36/40A61K36/575A61K36/752A61K36/8965A61K36/899A61K2236/19A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2300/00A23V2200/30A23V2250/21
Inventor 刘剑利王帅曹向宇阎笑何勇林李润昊孙铭泽
Owner LIAONING UNIVERSITY
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