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Extraction method of immature bitter orange extract

A Citrus aurantium extract, extraction method technology, applied in chemical instruments and methods, preparation of organic compounds, drug combination and other directions, can solve the problem that it is difficult for hesperidin to ensure the stability of profit margins, and the comprehensive development of Citrus aurantium extract is not possible. , the price trend is not very clear and other issues, to achieve the effect of green production process, increase the utilization rate of the plant, reduce the vacancy time of the plant

Active Publication Date: 2020-07-10
永州华茂生物科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005]Currently the price of Citrus aurantium is relatively high and fluctuates frequently, and the price trend is not clear
If in the production process, only hesperidin is extracted and other active ingredients are not extracted, the obtained hesperidin will hardly guarantee a stable profit margin
However, in the prior art, the extract of Fructus Aurantii has not been fully developed.

Method used

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  • Extraction method of immature bitter orange extract
  • Extraction method of immature bitter orange extract
  • Extraction method of immature bitter orange extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Taking Citrus aurantium as raw material, the specific technological process for comprehensively preparing its extract is as follows:

[0062] Source of raw materials: Aurantium citrus produced in Yichang, Hubei Province. According to HPLC detection, the content of hesperidin is 23.45%, and the content of synephrine is 0.89%. The content of total flavonoids is about 5.34% by UV-visible spectrophotometer.

[0063] (1) Pretreatment of Citrus aurantium

[0064] Choose the citrus aurantium raw material with a diameter of less than 1.5 cm, soak it in water overnight to make it completely infiltrated, crush it into pieces, add 30BV of water to it, adjust the pH=2, and heat and extract at 70°C for 3 hours. Filter and wash the raw material with 5BV water.

[0065] (2) Extracted pectin

[0066] After combining the boiled liquid obtained in step (1) and the washed liquid, concentrate to one-third of the original volume, and set the concentration conditions at 70°C and concentrat...

Embodiment 2

[0078] Taking Citrus aurantium as raw material, the specific technological process for comprehensively preparing its extract is as follows:

[0079] Source of raw materials: Citrus aurantium produced in Changde, Hunan Province. According to HPLC detection, the content of hesperidin is 16.65%, and the content of synephrine is 1.39%. The content of total flavonoids is about 6.21% through UV-visible spectrophotometer detection.

[0080] (1) Pretreatment of Citrus aurantium

[0081] Choose the citrus aurantium raw material with a diameter of less than 1.5cm, soak it in water overnight to make it completely infiltrated, crush it into pieces, add 30BV of water to it, adjust the pH to 2, and heat and extract at 75°C for 4 hours. Filter and wash the raw material with 5BV water.

[0082] (2) Extracted pectin

[0083] After combining the boiled liquid and the washed liquid obtained in step (1), concentrate to one-third of the original volume, and set the concentration conditions at 70°C...

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Abstract

The invention discloses an extraction method of an immature bitter orange extract. The extract comprises pectin, synephrine, hesperidin, total flavonoids of immature bitter oranges, plant fibers and the like. The extraction method comprises the steps: selecting an immature bitter orange raw material with a diameter of less than 1.5 cm; extracting with a hydrochloric acid solution to obtain a mixture of pectin and synephrine, and further separating and purifying to obtain pectin and synephrine products; extracting with a sodium carbonate solution to obtain an immature bitter orange total flavone product; extracting with sodium hydroxide to obtain a hesperidin product; and the finally extracted residues are pure plant fibers. Various products are comprehensively developed from immature bitter oranges by using various methods, and the complete utilization of materials is ensured so that the production cost is reduced, and the environmental pollution is reduced.

Description

technical field [0001] The invention belongs to the technical field of extracting plant components, and in particular relates to a method for extracting citrus aurantium extract. Background technique [0002] Citrus aurantii, the name of traditional Chinese medicine. Rutaceae lime Citrus aurantium L. and its cultivars or sweet orange Citrus sinensis Osbeck of dried young fruit. Citrus aurantium is usually spherical, and the commercially available citrus is usually whole or sliced. Between 0.5-2.5cm in diameter, the exocarp is black-green or dark brown-green, with granular protrusions and wrinkles, and obvious style remnants or fruit stem marks. Cut surface mesocarp slightly raised, yellowish-white or yellowish-brown, 0.3-1.2cm thick, with 1-2 columns of oil chambers on the edge, brown sac. Quality is hard. Gas fragrance, bitter, slightly sour. Wherein the sliced ​​Fructus Aurantii has a longer fruit development time and the content of active ingredients is lower th...

Claims

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Application Information

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IPC IPC(8): C07C213/10C07H1/08C07H17/07C08B37/00C07G99/00A61K36/752A61P3/06A61P9/00A61P9/10D01C1/00
CPCC07C213/10C07H1/08C07H17/07A61K36/752C08B37/0048A61P3/06A61P9/10A61P9/00D01C1/00A61K2236/333C07G99/00C07C215/60
Inventor 蒋亦轩莫卓群冯博文
Owner 永州华茂生物科技有限责任公司
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