299 results about "Cinnamates" patented technology

Novel compounds, their methods of preparation and use in therapies related to cancer and inflammation are provided. Compounds comprise esters of cinnamic acid, vanillic acid and 4-hydroxy cinnamic acid and derivatives and salts thereof. Compounds with novel benzofuran lignan structure as a potent antimitotic agent and inducer of apoptosis are provided. Formulations and methods for treatment of diseases mediated by NF-kappaB are also provided.

The compositions of this invention comprise a mixture of (1) phenylalanine and a dietary food supplement, (2) leucine and a dietary food supplement, and (3) hydrocinnamic acid and a dietary food supplement. The compositions are used for medicinal purposes to alleviate a variety of maladies.

An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.

The invention relates to new polymerisable mesogenic or liquid crystalline compounds comprising a laterally substituted cinnamate group, to polymerisable mesogenic or liquid crystalline mixtures and anisotropic polymers prepared thereof, and to the use of the new compounds and the mixtures and polymers prepared thereof in optical and electrooptical devices, adhesives, synthetic resins with anisotropic mechanical properties, cosmetics, diagnostics, liquid crystal pigments, decorative and security applications, nonlinear optics, optical information storage, electronic devices like organic field effect transistors (FET or OFET), electroluminescent devices, or as chiral dopants.

The present invention provides several methods for biological production of para-hydroxycinnamic acid (PHCA). The invention is also directed to the discovery of new fungi and bacteria that possess the ability to convert cinnamate to PHCA. The invention relates to developing of a new biocatalyst for conversion of glucose to PHCA by incorporation of the wild type PAL from the yeast Rhodotorula glutinis into E. coli underlining the ability of the wildtype PAL to convert tyrosine to PHCA. The invention is also directed to developing a new biocatalyst for conversion of glucose to PHCA by incorporation of the wildtype PAL from the yeast Rhodotorula glutinis plus the plant cytochrome P-450 and the cytochrome P-450 reductase into E. coli. In yet another embodiment, the present invention provides for the developing of a new biocatalyst through mutagenesis of the wild type yeast PAL which possesses enhanced tyrosine ammonia-lyase (TAL) activity.

The invention provides a method for extracting and separating rare earth elements in a hydrochloric acid system. The method includes the steps: taking mono (2-ethylhexyl) phosphonate 2-ethylhexyl methoxy cinnamate trialkyl methyl ammonium or phosphonate (2-ethylhexyl) diester trialkyl methyl ammonium as an extracting agent; taking normal heptane as diluent; and extracting the rare earth elements in rare earth chloride water solution into the normal heptane. The extracting agent used in the method does not need to be saponified, extraction and reverse extraction acidity is low, and separation coefficient for the rare earth elements is high.

Unique photoprotective compositions contain novel methyltrialkylsilanes bearing a cinnamate, cinnamamide, benzalmalonamide or benzalmalonate function, useful as sunscreens that are active in the field of UV radiation.

The invention discloses a method for preparing the product of active lactic acid galactococcus, which comprises the technical processes of constructing strains (constructing, connecting, transforming and selecting plasmids), preparing a fermentation culture medium, activating the strains, inoculating, fermentaing and drying. The strains with high expression and an optimized medium formulation are used in the method, the methods of pH control and the like are adopted for prolonging the logarithmic phase of the thalli, the density of the thalli in a fermenting system is increased by 100 times, the yield of living thalli is larger than 10 CFU / ml, and the expressing quantity of a PAL protein is larger than 12 percent. The obtained thalli have the ability for efficiently transforming phenyl alanine into cinnamylate, and the specific enzyme activity of the PAL is larger than 50U / g. The stability of the obtained thalli powder is good and can be kept for six months under 4 DEG C, the number of the living thalli can reach more then 10 CFU / g, and the specific enzyme activity of the PAL is not obviously reduced. The fermenting cost is reduced by 2 / 3. The PAL with low cost can be conveniently and largely provided for PKU treatment by using the invention.

The present invention relates to organoslicon modified cinnamate as reactive ultraviolet ray absorbent and its preparation process and application in preparing organic siloxane polymer and composite ultraviolet ray resisting material.

The invention discloses a microcrystalline-cellulose-modified rubber material composed of the following raw materials, by weight: 3-4 parts of an anti-aging agent BPS, 0.2-0.6 parts of 8-10% sulfuric acid, 26-30 parts of melamine, 5-8 parts of a 37% formaldehyde solution, 7-10 parts of urea, 6-10 parts of microcrystalline cellulose, 1-1.2 parts of isopropanol, 2-3 parts of sulfur, 3-4 parts of maleic anhydride, 210-230 parts of neoprene S40V, 3-4 parts of sodium fluosilicate, 20-26 parts of montmorillonite powder, 5-7 parts of tetrabutyl titanate, 20-24 parts of carbon black, 0.4-1 parts of sodium cinnamate, 2-3 parts of abietinol, 2-4 parts of palm wax, and 1-2 parts of dimethylaminopropylamine. According to the invention, microcrystalline cellulose is processed with the crosslinking effect of maleic anhydride, and is blended with abietinol, such that surface viscosity is improved, material compatibility is promoted, and good antioxidant effect is provided. Microcrystalline cellulose forms a closer network structure in melamine resin formed by melamine, urea and formaldehyde, such that resin viscosity and tensile deformation resistance are well improved, and certain reinforcement and tackifying effects are provided in the rubber material. Therefore, flexural cracking resistance, hot-air aging resistance and stability of the rubber material are improved.

A beverage product contains a preservative system comprising 20-250 mg / L benzoic acid or salt thereof, 20-250 mg / L sorbic acid or salt thereof, and 10-100 mg / L cinnamic acid or salt thereof where the benzoic acid or salt thereof to sorbic acid or salt thereof mass ratio is greater than 1:1 while the mass ratio of benzoic acid or salt thereof to the total sorbic and cinnamic acids or salts thereof is approximately 1 or less. In particular the preservative blend comprises potassium benzoate, potassium sorbate, and potassium cinnamate.

A thermoplastic composition includes a polyolefin having a polymeric backbone and, associated therewith, one or more ionic compounds having a central metal element and one or more carboxylic acid functional moieties. The thermoplastic composition may be, for example, polyethylene or polypropylene. A method of improving the mechanical properties of thermoplastics includes adding, to a thermoplastic composition having a polymeric backbone, an additive including one or more ionic compounds having a central metal element and one or more carboxylic acid functional moieties, wherein the additive is added to the thermoplastic composition at conditions suitable to associate the one or more ionic compounds to the polymeric backbone. The ionic compounds may be, for example, zinc cinnamate, zinc hydrocinnamate, zinc naphthoate, zinc naphthalene acetate, isophthalic acid zinc salt, and phthalic acid zinc salt, and their equivalents substituting calcium or magnesium instead of zinc as the central metal element, and mixtures thereof.

The invention discloses an organic solid base catalyst for synthesizing alpha-cyanoethyl cinnamate. The preparation method of the organic solid base catalyst for synthesizing alpha-cyanoethyl cinnamate comprises the following steps: by using chloropropyltrimethoxysilane as a coupling agent and cyclohexane as a solvent, grafting an N-butylimidazole basic ionic liquid onto a silica gel supporter by ultrasonic technology, thereby obtaining the organic solid base catalyst for synthesizing alpha-cyanoethyl cinnamate. The method for synthesizing alpha-cyanoethyl cinnamate by using the catalyst comprises the following steps: evenly mixing benzaldehyde and ethyl cyanoacetate in a mol ratio of 1:(0.9-1.1), adding the organic solid base catalyst which accounts for 2 wt% of the reactants into the reaction kettle, heating to 80-110 DEG C while stirring to react for 5-12 hours, and centrifugally settling to obtain the product, wherein the organic solid base catalyst can be recycled and used repeatedly. The catalyst disclosed by the invention has high catalytic activity and can be used repeatedly.

A lappaconitine aza-cinnamic acid derivative having the following formula (I):X is C or N, and R1, R2, and R3 are independently H or lower alkyl. A method of preparing the lappaconitine aza-cinnamic acid derivative of formula (I) is also disclosed.

The invention discloses a bionic marine antifouling paint which comprises the following raw materials in parts by weight: 30-45 parts of fluorinated acrylic ester, 20-35 parts of silicone rubber, 2-10 parts of biological antifouling agent, 15-25 parts of filler, 0.5-1 part of organic bentonite, 0.5-1 part of polyethylene wax and 2-7 parts of propylene glycol. According to the bionic marine antifouling paint disclosed by the invention, P-cinnamate sulfate in the biological antifouling agent has a remarkably strong attachment inhibiting effect on marine bacteria and barnacle; homarine can prevent attachment of marine benthic diatom and barnacle; diterpene formamide has a function of inhibiting barnacle and shellfish larvae; the rubber silicon material and fluorinated acrylic ester material have extremely low surface free energy, low friction coefficient, high hydrophobicity and high contamination release performance, so that attachments are not easily attached or are insecurely attached.

The invention provides a method for extracting and separating rare earth elements in a sulfuric acid system. The method includes the steps: taking mono (2-ethylhexyl) phosphonate 2-ethylhexyl methoxy cinnamate trialkyl methyl ammonium as an extracting agent; taking normal heptane as diluent; and extracting the rare earth elements in rare earth sulfate water solution into the normal heptane. The extracting agent used in the method does not need to be saponified, extraction and reverse extraction acidity is low, and separation coefficient for the rare earth elements is high.

The invention relates to a preparation method of cinnamate esters and derivatives thereof, which is shown as the following chart, wherein, R1 is hydrogen, 4-methoxyl or 3-nitryl; R is methyl, ethyl or isopropyl; the preparation takes substituted benzaldehyde and acetone as raw materials and then carries out condensation to obtain substituted benzalacetone under the condition of a NaOH solution. The obtained substituted benzaldehyde carries out 'one-pot' reaction with copper oxide, iodine, pyridine and alcohol, and potassium carbonate is added, and then the cinnamate esters and the derivatives thereof can be obtained. The preparation method of the invention has advantages of cheap raw materials, simple operation, moderate reaction condition and environmental friendliness, and provides a feasible preparation method of the cinnamate esters and the derivatives thereof for industry.

Provided is an oil-in-water emulsion sunscreen cosmetic composition that can provide high protection ability against UVA and excellent emulsion stability. The oil-in-water emulsion sunscreen cosmetic composition is characterized in that it contains (A) a hydrophobized zinc oxide having an absorbance of 0.3 or more at a wavelength of 370 nm, (B) a UVA absorber being solid at room temperature, (C) a UVB absorber, (D) a liquid-state higher fatty acid, (E) a nonionic surfactant, (F) a volatile oil, (G) a quaternary ammonium compound having a long-chain aliphatic group and (H) water. Particularly, it is preferable that the hydrophobized zinc oxide has an average particle size within a range of 35 to 100 nm; the hydrophobized zinc oxide is hydrophobidized by use of hydrogen dimethicone; the quaternary ammonium compound having a long-chain aliphatic group is distearyldimethylammonium chloride; and the UVB absorber is octylmethoxy cinnamate.

The invention relates to preparation of a poplar antimicrobial compound and application thereof as an antimicrobial. The antimicrobial compounds are traced and separated from 107 branches of poplar in Europe and America; and through structural analysis, the antimicrobial compounds are para-hydroxy fat alkanol ester cinnamate, 5-hydroxy-7-methoxyflavone, 5, 7-ferrichrysin and 5, 7-dihydroxyflavanol. The invention first defines that flavone compounds are major antimicrobial compositions in the poplar, and simultaneously defines that extracts of the 107 poplars in Europe and America and antimicrobial compositions thereof have obvious inhibition activity to various phytopathogens, and can be used for prevention and treatment of insect pests and plant disease.

The invention discloses a microcapsule type flame retardant and a preparation method thereof. The flame retardant comprises the following components in parts by weight: triaryl phosphate, a phenolic resin, aminomethyl phosphonic acid, a coupling agent, a flame-retardant synergist, cinnamate, coumarin ester, nano chitosan, gelatin, sodium alginate, a natural fiber, and the like. The preparation method of the microcapsule type flame retardant comprises the following steps: (1) mixing the triaryl phosphate and the phenolic resin according to a formula, stirring, further adding an anionic emulsifier, gulcomannan, the aminomethyl phosphonic acid, the coupling agent, the flame-retardant synergist and an antioxidant, continuously stirring, further adding a natural fiber, stirring, and performingextrusion; (2) mixing the nano chitosan, the gelatin and the sodium alginate, uniformly stirring, further adding baicalin, the cinnamate and the coumarin ester, and stirring; (3) mixing products of the step (1) and the step (2), thereby obtaining the microcapsule type flame retardant. The microcapsule type flame retardant disclosed by the invention is good in thermal stability, good in flame retardancy and small in environment damage.

The invention relates to a cinnamate type ultraviolet sun-screening agent molecular engram solid-phase extraction column as well as preparation and application thereof, and belongs to the technical field of solid-phase extraction of detection analysis. According to the invention, iso-octyl p-methoxycinnamate is adopted as a template molecule, methacrylic acid is adopted as a functional monomer, ethylene glycol dimethyl acrylic ester is adopted as a crosslinking agent, azodiisobutyronitrile is adopted as an initiating agent, cinnamate type ultraviolet sun-screening agent molecular engram polymer microspheres are obtained by virtue of a precipitation polymerization method, and the obtained polymer microspheres are filled into a solid-phase extraction column through a wet method. The molecular engram polymer solid-phase extraction column provided by the invention can selectively adsorb a cinnamate type ultraviolet sun-screening agent, and compared with a conventional solid-phase extraction column, the molecular engram polymer solid-phase extraction column overcomes the defect of poor selectivity of a conventional solid-phase extraction filler, is strong in adsorptivity, high in extraction recovery rate, and achieves efficient selective separation, enrichment and purification of a trace amount of the cinnamate type ultraviolet sun-screening agent in various environments and biological samples.

The invention relates to a novel preparation method of phytosterol cinnamate. According to the technical scheme, the preparation method comprises the following steps of: adding cinnamic acid and phytosterol to a reaction bottle with a branch pipe under the conditions of no solvent and nitrogen introduction, heating until the mixture is completely melted, next, adding an ionic liquid and a cerous triflate compound catalyst, carrying out an esterification reaction at a temperature in the range from 100 to 170 DEG C for 2-10 h, detecting the reaction process by using high performance liquid chromatography and thin-layer chromatography, and separating through column chromatography to obtain the pure phytosterol cinnamate product after the reaction is finished. The method provided by the invention is simple to operate, high in yield and friendly to environment; the catalyst is easy to recover and can be reutilized.