The invention discloses a pharmaceutical composition providing effects of anti-bacterial, inflammation eliminating and delaying for male, wherein the pharmaceutical composition comprises 20% of ginseng rhizome, 10% of freshwater sponge, 10% of seal penis, 10% of a clove extract, 5% of hippocampus, 5% of gecko, 5% of chive, 5% of hibiscus esculentus l, 5% of eucommia ulmoides, 5% of epimedium, 5% of cynomorium songaricum rupr, 0.1-0.3% of chlorhexidine acetate, and a proper amount of 1-3-butanediol. According to the present invention, the lotion can treat kidney-yang insufficiency, blood and essence deficiency, sore and weak waist and knees, impotence, spermatorrhea, intestine dryness and constipation, has effects of blood pressure lowering, blood glucose lowering, diuresis promoting, cough stopping and phlegm expelling, can provide different degrees of regulation effects for immune system, endocrine system, central nervous system, circulatory system and urinary system, can provide effects of abdominal flatulence relieving, gastric secretion increasing, digestive capacity enhancing, nausea and vomiting reducing, kidney tonifying, essence benefiting and yang benefiting, and can be used for impotence, nocturnal emission, urinary incontinence, and leucorrhea.