The invention relates to an antibiotic-free premix for a growing rex rabbit. The antibiotic-free premix comprises the following components in percentage by weight: 3%-8% of mannan oligosaccharide, 2%-4% of bacillus subtilis, 2%-4% of lactobacillus, 2%-4% of acid proteinase, 2%-4% of amylase, 2%-4% of cellulase, 1%-3% of garlicin, 3%-8% of fromadriamycin, 0.5%-1.5% of ethoxyquin, 1.5%-3% of robenidine hydrochloride, 2%-8% of ferrous sulfate, 2%-5% of copper sulfate, 0.2%-1% of manganese sulfate, 1.5%-3% of zinc sulfate, 0.02%-1% of potassium iodide, 0.1%-0.2% of sodium selenite, 0.15%-0.25% of cobalt chloride, 10%-20% of dicalcium phosphate, 5%-12% of calcium carbonate, 2%-4% of multivitamin, 1%-3% of L-lysine hydrochloride, 2%-4% of DL-methionine and the balance of defatted rice bran. The antibiotic-free premix disclosed by the invention can promote the establishment of the intestinal function of the growing rex rabbit, improve the intestinal health and enhance the digestion utilization ratio of growing rex rabbit feeds and is convenient to use by users.