33 results about "Preventive vaccination" patented technology

The invention discloses a method for breeding French rex rabbits. The method comprises rabbit house establishment, breeding of breeding rabbits, breeding of the rabbits in a breeding period, disinfection of a colony house and vaccination. According to the method for breeding the French rex rabbits, the breeding method is simple, the survival rate of the French rex rabbits is increased from 70% to over 80% through self-breeding and self-cultivation, the growth speed of the French rex rabbits is high, the fattened French rex rabbits are good in meat quality, thick in skin, good in skin quality, high in slaughtering rate, small in consumed concentrated feed, low in breeding cost, high in operability and capable of effectively improving the use rate of the feed. In addition, the young rabbits are regularly vaccinated and the colony house is regularly disinfected, so that the immunity, the disease resistance and the survival rate of the French rex rabbits are greatly increased. Compared with a traditional rex rabbit breeding technology, the method is high in economic benefit and social benefit.

The invention relates to a respiratory syncytial virus vaccine, and the preparation method and application, in particular to an application of escherichia coli to express and recombinant respiratory syncytial virus G protein and mutation G protein, and preparation vaccine with nontoxic typed escherichia coli heat labile enterotoxin, for human or animal preventive inoculation, and for respiratory syncytial virus resistance, belonging to the field of biotechnology. The respiratory syncytial virus vaccine is characterized in that: the respiratory syncytial virus subunits vaccine comprises lopped respiratory syncytial virus RSV protein G, and further comprises nontoxic typed escherichia coli heat labile enterotoxin LT adjuvant. The vaccines are lopped respiratory syncytial virus RSV protein G containing amino acid between aa130 and 230 of the original G protein, and substitutes the amino acid CAWIC (CX3C module ordered) between aa182 and 186 with the amino acid YLEKESIYY (CTL epitope) on the RSV M protein, forming the GCIL protein. The respiratory syncytial virus vaccine has the advantages of remarkable practical significance for preventing human respiratory syncytial virus infection.

A digital disease control information integration and intelligent public health management platform comprises a management platform server, a database server, an OA office system, a disease surveillance system, an inspection report system, a medical information system, a child preventive vaccination management system, an internal network, an external network, a child preventive vaccination outpatient department, a disease surveillance terminal, a health hazard factor monitoring terminal, a serious disease special reporting system, a public health emergency commanding system, an expert system, a medical information workstation, a monitoring terminal, a testing laboratory, a subordinate unit system, a superior unit system and an information searching and publishing system. All disease data collection and the whole data monitoring of diseases are achieved, and data samples can cover all people and the whole periods of the diseases. Dynamic quality control management is achieved, and therefore management quality and the accuracy of the data are guaranteed, quality control cost and administrative management cost are lowered, and disease prevention and management efficiency is improved.

The invention relates to medicine technique domain. At present, the hepatitis vaccine is in common use of protective inoculation of hepatitis. The current formulation is injection, with the shortcomings of high cost, poor tolerance and need specialized technical personnel administrating. The chitosan nanoparticles preparation is formed by ionic crosslinking-high pressure homogeneization technique through hepatitis vaccine model and chitosan as carrier material, furthermore the chitosan nanoparticles are surface modified by lectin to obtain nanoparticles preparation suitable for oral inoculation. The said nanoparticles preparation vaccine provides a new route of oral inoculation to prevent hepatitis B, with high operability and low cost.

The invention discloses a children immunization program information management system which comprises a children's preventive vaccination certificate, a doctor mobile communication platform and a database. The preventive vaccination certificate is printed with two-dimension codes comprising vaccination children related information; the mobile communication platform is equipped with a preventive vaccination information processing program, wherein the processing program comprises a medicine usage registration module, a vaccination information input module and a vaccination information sending module. The medicine usage registration module is used for recording information of medicine used by a doctor every time; the vaccination information input module is for reading the two-dimension code information on the children's preventive vaccination certificate and for carrying out selection and confirmation on vaccination site, vaccination mode and vaccination medicine information of each vaccination child every time; the vaccination information sending module is for carrying out encryption on the input vaccination information and sending the information to the database, vaccination data being automatically generated when the information is sent; and the database can automatically decode the received vaccination information and can dynamically carry out statistical analysis.

Provided are a vaccine scheduling device and vaccine scheduling program making it possible to put together a schedule for preventive vaccination in a manner more suitable for a preventive vaccination subject, as well as a computer-readable recording medium storing this program.A schedule creation unit (13) has a provisional schedule creation unit (13a) and a final schedule creation unit (13b). The final schedule creation unit (13b) reads information on a prohibition period corresponding to a past disease indicated by a designated person's clinical history data received by a clinical history data receiving unit (14), sets a prohibition period starting from a fixed date indicated by the clinical history data and, if there are scheduled administration dates in a provisional schedule created by the provisional schedule creation unit (13a) in the time period from the current point in time until a final date of the prohibition period, creates a final schedule in accordance with the number of days of difference between the earliest one of these scheduled administration dates and a release date when the prohibition period is released.

The invention discloses a respiratory syncytial virus F2 protein subunit vaccine and a preparation method thereof. The method constructs a recombinant expression vector F2 / pFN18K, and transforms the recombinant expression vector into Escherichia coli to form a recombinant engineering bacterium. The recombinant engineering bacterium undergoes Fermentation culture, high-efficiency expression of Halo-F2 protein was obtained in Escherichia coli by rhamnose induction, and F2 protein with high purity was obtained by digestion with tobacco plaque virus protease (TEV) and chromatographic purification; animal experiments of the present invention showed that, F2 protein has strong immunogenicity and can stimulate the body to produce a better immune response. It is used for human or animal vaccination to resist respiratory syncytial virus infection. Prokaryotic expression of F2 protein in Escherichia coli can improve the expression level of protein vaccines , which has important practical significance for large-scale production and clinical application.

The invention discloses a children preventive vaccination management system. The children preventive vaccination management system comprises a children RFID (Radio Frequency Identification) label, a reader-writer, a management platform and a memorizer, wherein the children RFID label, the reader-writer, the management platform and the memorizer are sequentially connected; and the children preventive vaccination management system is characterized by also comprising a reminding device, wherein the reminding device is connected with the management platform through a wired or wireless way, and the reminding device comprises a short message reminding module, and / or an email reminding module and / or an automatic telephone reminding module. The children preventive vaccination management system also comprises a medicine RFID label, and the memorizer also comprises a medicine information database.

The invention provides a porcine rotavirus G4-G5-G9 type trivalent inactivated vaccine as well as a preparation method and application thereof, three genotype strains of current PoRV epidemic are adopted as seed viruses, are inactivated by BEI, and are emulsified with an adjuvant ISA201VG to prepare the PoRV trivalent inactivated vaccine. The trivalent inactivated vaccine prepared by the research has the characteristics of high immune protection rate, good stability, high yield, safety and reliability, and can be used for emergency vaccination when a PoRV epidemic situation outbreaks.

The invention discloses a preventive vaccination on-site emergency disposal box. Necessary equipment and rescue medicinal instruments for preventive vaccination abnormal reaction diagnosis are picked and arranged in the on-site emergency disposal box in a certain order. When preventive vaccination is carried out, the preventive vaccination on-site emergency disposal box is adopted; and the preventive vaccination on-site emergency disposal box can be prepared for nonuse, but cannot be unavailable in use. The medicinal instruments are complete in the box and reasonably placed layer by layer, so corresponding measurements can be taken orderly during acute vaccination reaction disposal.

The invention provides a method for quantitatively discriminating, evaluating and preventing the risk of a vaccination weak region. The method comprises the following steps of 1, dividing vaccinationchildren of the right age into groups of different ages, 2, determining the types of vaccination corresponding agents of different age groups, 3, collecting data, and counting the vaccination rate ofthe vaccine corresponding agent times in the previous jurisdiction, 4, quantitatively evaluating a risk value based on the vaccination rate of the corresponding dose of the vaccine, calculating a comprehensive risk value in a jurisdiction, and realizing safety risk quantitative evaluation, 5, dividing different jurisdiction areas into weak types according to the risk values, and 6, classifying andguiding the work of the current year according to different weak types, and assessing the work. The method is more objective, high in comparability and high in repeatability, has a guiding effect onimmune work, can realize regional guiding to realize effective monitoring, and reduces the workload.

The invention discloses an immune planning and vaccination management system. The system comprises an inoculated person identity uniqueness control verification module, wherein identity card information is read through an identity information identification device and stored for an adult inoculated person; for a child inoculated person or a guardian, after confirming that the inoculated person is himself or herself through vaccination certificate verification, face collection on the existing archive is performed through a face recognition device, comparison is synchronously carried out with a database , and photos if the comparison is passed are stored. The system also includes a module for verifying identity validity verification for each time of vaccination, which is used for verifying identity validity during subsequent vaccination; a business process management and control module used for managing each terminal and a system process; a database module used for storing the identity information, the inoculation information and the process information. The technical problems that in the prior art, in the immunization and prevention vaccination process, the vaccination accuracy of the vaccinated persons and the vaccination time accuracy cannot be guaranteed, and information of the neonatal vaccinated persons is input repeatedly are solved.

Chimeric replicons of North American Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) containing the 5' sequence of an avirulent strain of PRRSV and a 3' sequence of a virulent strain of PRRSV are provided. Further provided is a method of producing attenuated PRRSVfrom the chimeric replicon. Also provided are compositions containing the replicon or attenuated virus. Vaccines and a method of vaccinating pigs against PRRSV are also provided.

The invention provides a bivalent attenuated vaccine for porcine epidemic diarrhea and porcine deltacoronavirus and a preparation method thereof. By adopting a cell continuous passage method and a cell suspension culture technology, the invention provides the bivalent attenuated vaccine which is high in immune protection rate, good in stability, high in yield, safe and reliable and is used for emergency prevention of inoculated porcine epidemic diarrhea and porcine deltacoronavirus, and an effective means is provided for prevention and control of PEDV and PDCoV.

The present invention discloses an on-site emergency disposal box for preventive vaccination, relates to the technical field of preventive vaccination and aims at problems that medicines and devices used in the existing vaccination cannot be placed in a protecting manner with a good storage mechanism and are more troublesome when being taken. The following scheme is provided: the on-site emergencydisposal box for preventive vaccination comprises a box body, an inside of the box body is provided with a first movable box and a second movable box, insides of the first movable box and the secondmovable box are both provided with a buffer mechanism, left sides of the first movable box and the second movable box are fixedly connected with a connecting plate, an inside of the connecting plate is movably provided with two guiding rods welded with an inner wall of a left side of the box body in a sleeving manner, a left side of the connecting plate is connected with a first elastic rope and asecond elastic rope, and one end, away from the connecting plate, of the first elastic rope is fixedly connected with an inner wall of the box body. The on-site emergency disposal box facilitates classification and buffer protection of inoculation articles, and is also convenient for medical personnel to quickly take and beneficial to rapid progress of inoculation work.

The invention relates to the technical field of child vaccination information management, and discloses a child vaccination information management system based on the Internet of Things. The system comprises a block database server A, a block database server B, a block database server C and a block database server N, wherein vaccination information management software is installed and operated inthe block database server; any block database server is used as a block node to be connected to form a vaccination information block chain network, and vaccination information management software identifies vaccinated children in a mode of vaccination children names and vaccination children identity card numbers or vaccination children birth certificate numbers. Further, an intelligent terminal or / and a PC terminal synchronously shares the child vaccination information corresponding to the access permission at the vaccination information management software client. The technical problem that an existing child vaccination information management system cannot support parents of vaccination children to store vaccination record books in an electronic data format is solved.

The invention relates to the technical field of information management and particularly relates to an information pushing device for preventive vaccination and physical examination management. The information pushing device comprises a cabinet body, wherein a transverse plate is mounted at the middle part of the front face of the cabinet body, a fingerprint identifier is mounted at one side of thetransverse plate, a plurality of supporting plates are horizontally mounted inside the cabinet body, information carriers are mounted between adjacent supporting plates, a two-dimensional code is stuck to one side of each information carrier, a second threaded rod is mounted at the lower part of the inner side of the cabinet body, one end of the second threaded rod is rotatably connected with thecabinet body, the outer side of the second threaded rod is in threaded connection with an L-shaped moving plate, the outer side of a first threaded rod is in threaded connection with a moving block,and an electric pusher bar and a two-dimensional code scanner are mounted at one side of the moving block. Compared with the prior art, the information pushing device has the advantages that the structure is simple, the use is convenient, information extraction is good in effect and is timesaving and laborsaving, the use of a user is facilitated greatly, the practicability is high, and thus, the information pushing device is worthy of popularization.

The invention discloses a vaccine management method and system based on an electronic supervision code, and the method comprises the steps: in a vaccine storage process, recognizing the vaccine electronic supervision code through a vaccination scanning terminal, and receiving vaccine anti-counterfeiting verification information returned by a vaccine management database; comparing whether the vaccine anti-counterfeiting verification information is consistent with the corresponding vaccine basic information in the storage record, if so, recording and prompting a normal vaccine state, and updating the information to a vaccine management application system; in the vaccination process, the vaccination electronic supervision code is recognized through a vaccination scanning terminal, and basic vaccine information returned by the vaccine management database is confirmed and uploaded to a vaccination application system; and displaying vaccine information for confirmation of the recipient through the vaccination application system, and uploading the information of the recipient to a vaccine management database to be associated with vaccine anti-counterfeiting verification information marked by the vaccine electronic supervision code. And full information supervision on vaccine use and storage is realized.

The invention discloses a nursing workbench for vaccination, and relates to the technical field of vaccination. The nursing workbench comprises a table plate, a hollow layer and a lifting column; a storage cabinet and a support cabinet are mounted on the left side and the right side of the lower part of the table plate respectively; storage drawers are movably arranged in the support cabinet; a garbage box is movably hung outside the right side of the table plate; the hollow layer is arranged in the middle of the interior of the table plate; lifting rods are installed in the hollow layer, and a lifting plate is fixed to the upper portions of the lifting rods; the lifting column is installed on the left side of the upper portion of the table plate; and a fixing rod is fixed to the right side of the top end of the lifting column. The nursing workbench for vaccination has the beneficial effects that the nursing workbench for vaccination is reasonable in space distribution, the arm bearing position of a vaccination receiving person can be conveniently adjusted, the arm vaccination position of the vaccination receiving person can be automatically disinfected, the arm of the vaccination receiving person can be positioned and fixed, the vaccination process is prevented from being affected by struggling in the vaccination process, and low-temperature vaccination storage is facilitated.

The invention relates to infant vaccination clothes and trousers. The infant vaccination clothes and trousers comprise an upper garment body 5 and a trousers body 6. Openings of the outer sides of upper arm sleeves (near the deltoid muscle of the upper arm of the infant) of the jacket body 5 and the trousers body 6 and the outer sides of thigh parts (near the lateral muscle of the thigh of the infant) of trouser legs of the trousers body are about 20 cm, and zippers, buttons, magic tapes and the like are arranged on the edges of the two sides of the openings. Four independent openings are specially designed on the outer side of an upper arm sleeve (near the deltoid muscle of the upper arm of an infant) and the outer side of the thigh part of each trouser leg (near the lateral muscle of thethigh of the infant) of the infant clothes, and during infant vaccination, a vaccination part is selected as required, and zippers, buttons, magic tapes and the like on the outer sides of corresponding injection parts are unzipped; exposure of the body of the infant in the vaccination process is greatly reduced, and therefore the risk that diseases happen to the infant in the vaccination processis solved or reduced; and practicality is high.

The invention discloses a method for raising French rex rabbits. The method includes the construction of a rabbit house, the breeding of breeding rabbits, the cultivation of growing-up period, the disinfection of the enclosure and the vaccination. Adopting the breeding method of the present invention to breed rex rabbits, the feeding method is simple, and the survival rate of rex rabbits is increased from 70% to more than 80% through self-propagation and self-cultivation. At the same time, the growth rate of rex rabbits is faster, and the rex rabbits after fattening have good meat quality, good skin thickness and quality , The slaughter rate is high, and the consumption of concentrated feed is less, the cost of feeding is low, and the operability is strong, which effectively improves the utilization rate of feed. In addition, regularly vaccinate the pups and disinfect the pens, which greatly enhances the immunity, disease resistance and survival rate of the French Rex Rabbit. Compared with the traditional Rex Rabbit breeding technology, it has higher economic and social benefits. .

The present invention relates to secreted Chlamydia polypeptides, which may be expressed by a Gram-negative bacterial strain and secreted by the type III secretion pathway of said bacterial strain. The present invention also relates to polynucleotides coding for these polypeptides, as well as to the therapeutic and vaccination uses of these secreted Chlamydia polypeptides.

The embodiment of the invention discloses an immune inoculation management system, and the system comprises: a vaccine management module which is used for managing and maintaining vaccine types, vaccine characteristics, vaccine manufacturers, vaccine-related biological products, and packaging specifications of the biological products; the vaccine inventory management module that is used for managing inventory information of a plurality of vaccines in an outpatient service, and the inventory information comprises new vaccine batch number orders and vaccine and warehouse entering information; the immune program management module that is used for managing and maintaining a vaccination plan; the vaccination process management module that is used for realizing a vaccination process through intelligent equipment, displaying the vaccination service progress through an intelligent television and an LED screen, and monitoring outpatient service number taking, inquiry, registration, payment, vaccination and observation processes in real time; and the touch screen inoculation module that is used for inputting related information when the inoculation doctor performs inoculation on the recipient. The whole-process traceability of vaccines in the inoculation station is realized, and the digital management of the vaccines and the inoculation accuracy of the vaccines are realized.

The invention relates to a novel multi-source power supply system and method for a vaccination vehicle. The system comprises a power supply module, a control module, a voltage-stabilizing filter circuit and a contactor; the power supply module comprises a mains supply, a power battery pack and a storage battery; the contactor comprise a first contactor, a second contactor and a third contactor; the commercial power, the first contactor, the voltage-stabilizing filter circuit, the third contactor and the load equipment are connected in sequence; the power battery pack, the second contactor and the third contactor are connected in sequence; the storage battery is connected with the third contactor; the control module is respectively connected with the first contactor, the second contactor and the third contactor; and the control module is further connected with the output end of the mains supply, the output end of the voltage stabilization filter circuit and a load. The power supply stability and the power supply efficiency of the mobile vaccination vehicle are improved.

The invention provides a porcine epidemic diarrhea and porcine rotavirus bivalent inactivated vaccine and a preparation method thereof, and provides the porcine epidemic diarrhea and porcine rotavirus bivalent inactivated vaccine which is high in immune protection rate, good in stability, high in yield, safe and reliable and is used for preventing vaccination by adopting a cell continuous passage method and a cell suspension culture technology. And an effective means is provided for prevention and control of porcine epidemic diarrhea and porcine rotavirus.

The invention discloses a disease prevention inoculation device, and relates to the technical field of medical instruments, the disease prevention inoculation device comprises a box body, a mounting column is fixedly arranged at the bottom in the box body, the mounting column is rotatably sleeved with a feeding column, and a plurality of mounting cavities for placing injectors are formed in the peripheral surface of the feeding column; a plurality of sliding rods corresponding to the mounting cavities are arranged on the feeding column in a sliding mode in the axial direction, clamping plates are fixedly arranged at the top ends of the sliding rods, clamping openings are formed in the clamping plates, guide mechanisms are arranged between the mounting columns and the sliding rods, and when the feeding column drives the sliding rods to rotate around the mounting columns, the clamping openings are formed in the clamping plates. Part of the sliding rod moves upwards to pull out the push rod of the injector by a certain distance. The device is high in automation degree, by arranging the mounting column, the feeding column and the mounting cavity, an injector is inserted into a vaccine medicine bottle and placed in the mounting cavity, liquid medicine extraction is achieved, and the problems that the medical labor amount is large and time and labor are wasted due to the repeated medicine extraction process are solved.

The invention concerns the optimization of the wild R9M peptide and the use of the resulting peptides for therapeutic vaccination and / or preventive vaccination against leukaemia in humans. More particularly, the invention concerns mutated immunogenic peptides derived from the human TEL / AML1 fusion protein comprising the wild R9M peptide sequence Arg-Ile-Ala-Glu-Czs-Ile-Leu-Gly-Met. The invention also concerns polynucleotides coding for the mutated R9M immunogenic peptides, cellular expression vectors comprising nucleic acid sequences expressing the mutated R9M immunogenic peptides and polyclonal or monoclonal antibodies capable of being fixed on at least one of said peptides / polynucleotides. The invention further concerns the use of said peptides, polynucleotides and / or antibodies for preparing vaccines, anti-tumoral medicines and compositions and for in vitro and in vivo stimulation of the immune response in humans.

The invention discloses a physical examination information management and information pushing nursing device for vaccination, which belongs to the technical field of internet information, and comprises a base, a device main body, an NFC (Near Field Communication) sensing module arranged above the base and convenient for a user to operate, and a face recognition module mounted in the device main body and used for identity recognition, the face recognition device is installed in the device body and used for face recognition. The historical recording module and the traceless browsing mode are arranged in the touch display screen to be matched, after the face recognition module and the NFC induction module recognize and detect the user, the touch display screen can display historical vaccination or physical examination records of the user, the user can know the records conveniently, and the user experience is improved. And when the user leaves and the camera and the face recognition module do not recognize the current user, the touch display screen can directly close the current interface, so that information leakage caused by the fact that the user forgets to close the interface actively when the user leaves is avoided, and the information of the user can be effectively protected.

The invention relates to the technical field of information, in particular to a vaccination electronic informed agreement notification method based on a verification and signing instrument, comprising a vaccination server and a verification and signing instrument, the vaccination server is connected with a vaccination browser, and the vaccination browser and the verification and signing instrument perform data interaction through a websocket communication protocol. Data interaction between a browser and sign-off instrument hardware is realized based on webSocket, vaccine registration information, electronic signature information, fingerprints and image acquisition information are converted into electronic documents, and vaccination electronic informed agreement notification is realized; the method is applied to a solution of a vaccination outpatient service digital integrated management system of an informatization project in the medical industry. The problem that a paper vaccination informing agreement book is inconvenient to fill, look up and store is solved, the authenticity and reliability of informing of the electronic informing agreement book are guaranteed, and paperless office work is achieved.