The invention discloses an unmanned full-automatic book management system. On the basis of the original enclosed shelf book depository, thorough optimization and improvement are carried out; a book basket concept is introduced; the order of each borrower is processed in batches; and during the processes of book storage, book taking, book return, and book basket transmission and delivery, equipment is simplified, and the efficiency of a single functional component is improved, thus the integral system functions are optimized. The unmanned full-automatic book management system comprises a book shelf, a laneway vehicle, a laneway vehicle port, a delivery device, a book brought-out window and a book return window, a book basket and book cases individual from the book shelf. An enclosed shelf book depository management system manages and operates data information in a database of the enclosed shelf book depository system, completes the interaction among control systems of a collection system and the full-automatic enclosed shelf book depository, and finally the management operation of the books is completed through the full-automatic enclosed shelf book depository.