Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

69results about How to "Promote research progress" patented technology

Thin film field effect transistor type gas sensor and preparation method thereof

ActiveCN108447915AEnhanced room temperature gas-sensing effectImprove adsorption capacityTransistorMaterial analysis by electric/magnetic meansBottom gate bottom contactQuantum dot
The invention discloses a thin film field effect transistor type gas sensor and a preparation method thereof. The sensor is a thin film field effect transistor with a bottom gate top contact type structure or a bottom gate bottom contact type structure. A thin film field effect transistor with a bottom grid top contact structure is taken as an example. The transistor comprises a substrate, a gateinsulating layer and a channel active layer from bottom to top. The channel active layer is a quantum dot thin film. A source electrode and a drain electrode are deposited above the substrate. A gateelectrode is further led out of the substrate. The internal composition, the structure, the overall process of the corresponding preparation method and the parameters during all steps of the preparation method of the thin film field effect transistor type gas sensor are improved. The quantum dot thin film serves as a channel active layer and a gas sensitive layer at the same time, and the gas response of multiple parameters is comprehensively regulated by utilizing the grid bias voltage. As a result, the prepared gas sensor is high in sensitivity, low in power consumption and high in selectivity. The effect of detecting low-concentration target gases, such as NO2 and H2S, is achieved.
Owner:HUAZHONG UNIV OF SCI & TECH +1

Polysaccharide-base gel composite film, and preparation method and application thereof

The invention discloses a polysaccharide-base gel composite film, and a preparation method and application thereof. The preparation method comprises the following steps: adding a Curdlan solution, a sodium carboxymethyl cellulose solution and glycerol into any one or two of an edible polysaccharide-sodium alginate solution and a carrageenin solution, and regulating the pH value of the mixed solution to 4-8 to obtain a film forming solution; carrying out ultrasonic degassing, and pouring into a teflon plate; setting, carrying out sterilization treatment, cooling at 4 DEG C for 10-20 minutes, and carrying out drying and film peeling under certain conditions; and after the film is peeled, immersing the film in any one or two of a KCl solution and a NaOH solution for 5-20 minutes, and naturally airing. Common polysaccharide substances in food are used as the matrix, the glycerol is used as the plasticizer, and the Curdlan and sodium carboxymethyl cellulose are added to prepare the composite film. The composite film has the advantages of favorable mechanical properties, favorable water tightness and favorable heat stability, and is green, environment-friendly and edible.
Owner:JIANGSU DONGHUI BIO-TECH CO LTD

Edible composite cling film, and preparation method and application thereof

The invention discloses edible composite cling film, and a preparation method and application thereof. The composite film is prepared by the following steps: adding a polyvinyl alcohol solution, a chitosan solution, a phenolic acid substance and a plasticizer in an edible polysaccharide Curdlan suspension, adjusting the pH value of the mixed solution to 3-5, carrying out ultrasonic degassing to obtain a film-forming liquid, pouring the film-forming liquid into a polytetrafluoroethylene plate, carrying out heat preservation for carrying out a reaction for 8-10 minutes at a temperature of 90-120DEG C, carrying out sizing, carrying out sterilization treatment, carrying out ultraviolet irradiation treatment for 5-10 minutes, carrying out hot-air circulating drying treatment at a temperature of 90-120 DEG C for 30-60 minutes, and carrying out cooling at a temperature of 4 DEG C to obtain the edible composite cling film. The edible composite film provided by the invention has the advantagesof high tensile strength and high extensibility, has excellent integrity, tensile strength and extensibility after being stewed in boiling water for 1 hour, and can effectively prolong the shelf lifeof fruits, vegetables and the meat products.
Owner:NANJING AGRICULTURAL UNIVERSITY +1

Contact force calculating and force chain recognizing method for particles in three-dimensional particle system

The invention belongs to the technical field of particle system force chain recognition and relates to a contact force calculating and force chain recognizing method for particles in a three-dimensional particle system. The method comprises the steps of putting balls into a rigid container to form the three-dimensional particle system, utilizing a loading pressure head to pressurize the three-dimensional particle system, collecting an original sequence image and a target sequence image through an XCT scanner, utilizing a digital body related method to analyze the obtained original sequence image and the target sequence image to obtain stress of all points, then performing image edge detection on a target image, recognizing a particle centroid, reading coordinates of the particle centroid and position coordinates of contact points of all particles, establishing an equation set according to balance conditions of all the particles and solving the equation set to obtain magnitude and direction of contact force fi of all the contact point positions on each particle. The method has a simple principle, is convenient and flexible to use and has strong practicability, application environment friendliness and wide market prospect; in addition, required equipment is simple and easy to obtain, and measurement results are accurate.
Owner:QINGDAO TECHNOLOGICAL UNIVERSITY

Method and device for detecting ultraviolet (UV) sterilization effect

The invention discloses a method and device for detecting ultraviolet (UV) sterilization effect. The method comprises the following steps: (1) determining the relationship among the UV radiation strength, UV radiation time, and sterilization rate; (2) detecting the UV radiation strength; (3) obtaining the sterilization rate according to the UV radiation strength and a given radiation time. The device comprises a UV strength detection device, a time setting device, and a sterilization rate calculation module. The method and device can guarantee the effectiveness of a UV sterilization facility on killing bacteria (especially staphylococcus aureus), the sterilization process, which cannot be observed by naked eyes, can be evaluated and controlled, moreover, the UV sterilization facility can be stopped after the staphylococcus aureus is completely killed, the energy waste is avoided, and the practicality of the UV sterilization facility is improved.
Owner:ç½—æ—­

Multifunctional super-structure lens capable of being regulated and controlled by any polarization state, and manufacturing method thereof

ActiveCN114063202AOvercome the limitation of polarization controlOvercoming featureLensEngineeringMechanical engineering
The invention relates to a multifunctional super-structure lens capable of being regulated and controlled by any polarization state, and a manufacturing method thereof. The multifunctional super-structure lens comprises a substrate layer and first to third type structural units arranged on the substrate layer, the first type structural units are rectangular nano-columns which are different in length and same in width and are suitable for regulating and controlling X-ray polarized light, the second type structural units are rectangular nano-columns which are different in width and length and suitable for regulating and controlling Y-line polarized light, the third structural units are cylindrical nano-columns which are different in radius and suitable for regulating and controlling any polarized light, and the first to third structural units have the same period and height and are arranged on the substrate layer in a staggered mode according to the spatial multiplexing principle to correspondingly meet a preset phase required by regulation so as to make the orthogonal line polarized light and other polarized light subjected to off-axis and on-axis focusing on a confocal plane respectively. The lens can realize any polarization state regulation and control and coplanar zooming under a single wavelength, and overcomes the problem that an existing multifunctional super-structure lens can only be regulated and controlled by a limited polarization state.
Owner:SHENZHEN GRADUATE SCHOOL TSINGHUA UNIV

Tin-based metal-organic framework and preparation method thereof, and application of tin-based metal-organic framework as lithium ion battery negative electrode material

The invention discloses a tin-based metal-organic framework, a preparation method thereof and an application of the tin-based metal-organic framework as a lithium ion battery negative electrode material. The chemical formula of the tin-based metal-organic framework is [Sn2 (dobpdc)] n, and the dobpdc is 2, 5-dihydroxy phthalic acid ions. The preparation method comprises the following steps: addingstannous sulfate (SnSO4) and 2, 5-dihydroxy phthalic acid into distilled water, and performing hydrothermal reaction to obtain a target product. The tin-based metal-organic framework synthesized by the method can be used as a lithium ion battery negative electrode material to be assembled into a CR2032 lithium ion button battery. The synthesis method has the advantages of simplicity, cheap and easily available raw materials, high yield and low cost. When the tin-based metal-organic framework is directly applied to a lithium ion battery negative electrode material, the volume expansion effectin the alloying process can be effectively relieved, and the specific capacity of the complex is maintained at 1018mAh g<-1> after 200 times of cycles under the charge-discharge current density of 200mA g<-1>. Good stability and excellent electrochemical performance are shown in a rate test.
Owner:NANKAI UNIV

Method for extracting and predicting displacement of metal mine blasting pile under support of GIS

ActiveCN110119994AReduce depletion lossRealize the second delineationForecastingDesign optimisation/simulationPoint cloudEconomic benefits
According to a method, firstly, an open-pit mine blasting digital elevation model is constructed, a blasting center is determined based on the open-pit mine digital elevation model, blasting form change spatial distribution is measured, and finally the blasting displacement condition is predicted based on a generalized regression neural network. According to the method, geology related theories and technical methods are used for solving the problem of mine production. The subjects such as geography, geology and mining engineering are organically fused, a prediction model is established based on point cloud data, accurate prediction of the blasting pile displacement after blasting is achieved, the blasting pile displacement serves as ore body displacement to be superposed on the boundary ofan ore body, and secondary delineation of the ore body is achieved. The research progress in the field is promoted, meanwhile, beneficial guidance and help are provided for production of Jiangxi Dexing copper ore, the depletion loss of mine exploitation is reduced, and the economic benefits of mines are improved.
Owner:JIANGXI UNIV OF SCI & TECH +1

Photoelastic tester for particulate matters

The invention discloses a photoelastic tester for particulate matters. A carrying framework is arranged on a cabinet; a horizontal sliding bracket is fixedly connected to the carrying framework, and is supported by a steel column with a roller; a light source for emitting parallel light rays is arranged on the horizontal sliding bracket; a particulate container case is arranged in the carrying framework; two side faces of the particulate container case, which are vertical to the parallel light rays, are glass plates; a loading steel plate is arranged in the particulate container case; a slot,of which the size is the same as that of the loading steel plate, is formed in the particulate container case; the loading steel plate can freely get in or get out of the particulate container case through the slot; a horizontal steel tube with a slit is fixed on the carrying framework; a vertical steel tube is clamped and slide in the slit of the horizontal steel tube; a polariscope is fixed on the vertical steel tube; the mirror surface of the polariscope is parallel to the glass plates; the photoelastic tester also comprises a camera device which is opposite to the light source; and the carrying framework is arranged between the camera device and the light source. The photoelastic tester can track macroscopic physical quantities, such as force, displacement and the like, in real time, and comprehensively observing a mechanics performance test on the particulate matters.
Owner:TSINGHUA UNIV

Multi-polarization-state multifunctional super-structure lens based on spatial multiplexing and manufacturing method of multi-polarization-state multifunctional super-structure lens

The invention discloses a multi-polarization-state multifunctional super-structure lens based on spatial multiplexing and a manufacturing method thereof.The multifunctional super-structure lens comprises a substrate layer, a first type of structural unit and a second type of structural unit, the first type of structural unit and the second type of structural unit are arranged on the substrate layer, and the first type of structural unit is rectangular nano-columns with different lengths and widths; the first type of structural units are rectangular nano-columns with the same size and different rotating angles, the second type of structural units are rectangular nano-columns with the same size and different rotating angles, the first type of structural units and the second type of structural units are arranged on the substrate layer in a staggered mode according to the spatial multiplexing principle, preset phases of incident light in different polarization states are correspondingly met, and orthogonal linearly polarized light and circularly polarized light are enabled to be subjected to off-axis and on-axis focusing on a confocal plane respectively; and the first type of structural units and the second type of structural units realize regulation and control of orthogonal linearly polarized light and circularly polarized light through transmission phases and geometric phases respectively. According to the multifunctional super-structure lens, three-polarization-state regulation and control and coplanar zooming can be achieved under the single wavelength, and the problems that an existing multifunctional super-structure lens can only be subjected to dual-polarization-state regulation and control, and the focal plane changes after regulation and control are solved.
Owner:SHENZHEN GRADUATE SCHOOL TSINGHUA UNIV

Method for laser cladding of copper alloy powder on surface of copper substrate

A method for laser cladding of copper alloy powder on the surface of a copper base comprises the following steps: (1) , using a polishing tool for polishing the surface of a copper base workpiece to remove a surface oxide layer; cleaning the surface of the copper-based workpiece by using a detergent to obtain a copper-based surface with a clean surface; (2), fixing the copper-based workpiece on aworking platform; and (3), carrying out high-speed laser cladding on the copper-based workpiece by using laser cladding powder through a high-speed laser cladding optical fiber laser device. The lasercladding powder comprises the following chemical components in percentage by weight: 0.01%-0.25% of C, 0.5%-3% of B, 1%-4% of Si, 012% of Cr, 0.5%-14% of Fe, 10%-50% of Cu, 30%-80% of Ni, wherein a powder particle size interval is 25-150 microns and a sphericity degree is more than or equal to 80%. The method has the advantages that for specific laser cladding powder, a transition layer, a pre-coating layer and the like do not need to be added before cladding, a desired cladding layer is directly obtained through single-layer cladding in the mode that powder is fed from the center and the working included angle of the cladding head is controlled, and the process is simplified.
Owner:ZHEJIANG UNIV

Construction method and application of humanized CCR2 gene modified animal model

The invention provides a construction method and application of a humanized CCR2 gene modified animal model, and relates to the technical field of biology. According to the humanized CCR2 gene modified animal model constructed by the invention, the research progress of the fields related to the human CCR2 gene or protein can be accelerated; for example, the humanized CCR2 gene modified animal model is used for replacing a human to test a drug; and an effective model and a powerful tool are provided for a preclinical experiment of a CCR2 target drug. Preferably, a CRISPR / Cas9 gene editing technology is utilized in the invention; a mouse-derived Ccr2 gene is replaced with a human-derived CCR2 gene, so that a mouse model capable of interacting with an anti-human CCR2 antibody is constructed;compared with a common mouse, humanized transformation of key target molecules is achieved; and the mouse model can be used for screening and evaluating drugs for human CCR2 genes, and is a very idealpreclinical drug test model.
Owner:SHANGHAI BIOMODEL ORGANISM SCI & TECH DEV

Energy storage efficiency enhanced high-energy storage lead-free ferroelectric ceramic material and preparation method thereof

ActiveCN112919907AEfficient energy storage characteristicsHigh breakdown strengthChemical compositionFree energies
The invention relates to the field of functional materials and devices, discloses an energy storage efficiency enhanced high-energy storage lead-free ferroelectric ceramic material and a preparation method thereof, and aims at solving the problems of low breakdown field strength and low effective energy storage density of an existing energy storage ceramic material. The chemical composition of the ceramic is (1-x) NaNbO3-xCaTiO3, and x is more than or equal to 0.15 and less than or equal to 0.9. Preferably, x equals 0.15, 0.2, 0.25, 0.3, 0.35, 0.4, 0.5, 0.6, 0.7, 0.8 or 0.9. CaTiO3 of a perovskite structure is introduced into sodium niobate-based ceramic for doping modification for the first time, high energy storage density and high efficiency are obtained while high breakdown field strength is achieved, the research direction of doping modification is expanded, and the lead-free energy storage ceramic material with application prospects is prepared.
Owner:HANGZHOU DIANZI UNIV

Preparation method of standard quartz powder used for copying silicosis model

The invention discloses a preparation method of standard quartz powder used for copying a silicosis model. Natural crystals are adopted as raw materials of the quartz powder, and the preparation method includes the steps of putting quartz crystals into an agate ball milling tank for ball milling for 6 days, adding distilled water, conducting standing, then screening out a suspension containing quartz powder in demanded grain size, conducing drying and sedimentation after the suspension is completely subjected to standing, and then obtaining the quartz powder meeting requirements. The preparedquartz powder can be provided for researchers to copy animal models and cell silicosis models; by using the standard quartz powder with the uniform specification, experiment results among different researchers have comparability, and research on silicosis pathogenesis and treatment drugs is facilitated. The method is easy to operate and is easily applied to industrial production.
Owner:ZHEJIANG ACAD OF MEDICAL SCI

Bismuth ferrite barium titanate-based ceramics with high energy storage density and high power density and preparation method thereof

The invention discloses a bismuth ferrite barium titanate-based ceramic with high energy storage density and high power density and a preparation method thereof, using 0.67BiFeO 3 ‑0.33 BaTiO 3 Based on the system ferroelectric material, the bismuth layered material BaBi 2 Nb 2 o 9 According to a certain molar ratio, it is mixed into bismuth ferrite barium titanate-based ceramics, and a new type of energy storage ceramic material with high energy storage density and high power density is prepared by using a solid-state synthesis method. The chemical composition of the ceramic material is (1‑x) (0.67BiFeO 3 ‑0.33 BaTiO 3 )‑xBaBi 2 Nb 2 o 9 , where 0.02≤x≤0.1. The energy storage ceramic material that the present invention obtains, main performance parameter can utilize energy storage density W rec =3.09J / cm 3 , energy storage efficiency η=85.6%, under 100kV / cm electric field, power density P D =27.2MW / cm 3 , the current density can reach 543.95A / cm 2 . In addition, the preparation process is stable and reliable, the production cost is low, industrialized production is easy to realize, and at the same time, it meets the current requirements for lead-free environmental protection. It can be widely used in high-power microwave weapons, laser weapons, electromagnetic launchers, and pulse power systems of hybrid vehicles.
Owner:HANGZHOU DIANZI UNIV

Preheating heat preservation device for laser additive manufacturing

The invention discloses a preheating heat preservation device for laser additive manufacturing which is arranged on a cladding workbench of a laser additive. The preheating heat preservation device isprovided with a heat preservation cavity, wherein a heating temperature control unit and a workpiece clamping unit are arranged in the heat preservation cavity, an opening is formed in the top of theheat preservation cavity to allow laser to act on the additive material, and a cover is arranged at the opening. The preheating heat preservation device has the advantages that the blank of the preheating and heat preservation integrated equipment for experiments in the field of laser additive manufacturing research is filled up, an equipment solution is provided for controlling the key process of the working temperature in the laser additive manufacturing technology, and a foundation is laid for promoting research progress.
Owner:ZHEJIANG UNIV

Microorganism filtering and collection device and application method of microorganism filtering and collection device

The invention provides a microorganism filtering and collection device and an application method of the microorganism filtering and collection device, and belongs to the technical field of experimental facilities. The microorganism filtering and collection device comprises a net bag and a collection pipe, wherein the collection pipe is connected below the net bag; the collection pipe is communicated with the net bag; a switch is mounted at the lower end of the collection pipe; the maximum opening end diameter of the net bag is 5cm to 20cm. After sampled seawater is filtered through the microorganism filtering and collection device, microorganisms in the seawater are recycled; the microorganism filtering and collection device is convenient and rapid; the loss of the microorganisms is not caused; the collection efficiency of samples is improved and a research progress is promoted.
Owner:YELLOW SEA FISHERIES RES INST CHINESE ACAD OF FISHERIES SCI

Method for identifying granular system power transmission chain

The invention belongs to the technical field of granular system power transmission chain identification, and relates to a method for identifying a granular system power transmission chain. The method includes the steps that firstly, a granular system is loaded, and granular system images before and after deformation are collected to be used as an original image and a target image respectively; then, the original image and the target image are analyzed, and after a displacement field and a strain field in the granular system surface of the target image at the corresponding moment are obtained, the stress of each point is obtained according to the strain of each point in the strain field; afterwards, image edge detection is conducted on the target image, granular centroids are identified, the coordinates of the granular centroids and the position coordinates of contact points of all granules are read, a force equilibrium and torque equilibrium equation is established for each granule, and the size and orientation of contact force at different contact points on all the granules are acquired through calculation; at last, the contact force of each granule is drawn, and the graph which is continuously represented by the contact force between adjacent granules is the path of the power transmission chain. The method is simple, scientific in principle, convenient and flexible to use, high in practicability, large in development prospect and wide in applied range.
Owner:QINGDAO TECHNOLOGICAL UNIVERSITY

Method for preparing polysaccharide composite film by thermally stable recombinant bacterial laccase and application

The invention discloses a method for preparing a polysaccharide composite film by using thermostable recombinant bacterial laccase and application thereof. The composite film is prepared by adding a carboxymethyl chitosan solution, bacterial cellulose, phenolic acids, a plasticizer and a surfactant into edible polysaccharide Curdlan suspension, and adjusting the pH value of the mixed solution to 3-5; ultrasonically degassing, adding the thermostable recombinant bacterial laccase to obtain a film forming liquid; pouring the film-forming liquid into a polytetrafluoroethylene plate, performing heat preservation reaction at 90-120 DEG C for 8-10 minutes, shaping and sterilizing, performing ultraviolet irradiation treatment for 5-10 minutes, performing hot air circulation drying treatment at 90-120 DEG C for 30-60 minutes, cooling at 4 DEG C, controlling humidity and temperature, drying, and peeling off the film to obtain a composite preservative film, namely the polysaccharide composite film. The composite film prepared by the method has high tensile strength and strong extensibility, has better antioxidant and antibacterial activities, and can effectively prolong the shelf life of fruits, vegetables and meat products.
Owner:NANJING AGRICULTURAL UNIVERSITY +1

Nucleic acid molecule, PCR primer pair and kit for detecting beta-tubulin gene of trichomonad

The invention discloses a nucleic acid molecule, a PCR primer pair and a kit for detecting a beta-tubulin gene of trichomonad. Through extensive research, the inventor clones in trichomonad to obtain a trichomonad beta-tubulin full-length gene coding sequence as shown in SEQ ID NO: 1, and further designs, by utilizing the beta-tubulin full-length gene coding sequence, a PCR primer pair capable of detecting the trichomonad beta-tubulin gene and the transcriptional level of the trichomonad beta-tubulin gene and corresponding PCR reaction conditions; and further, the kit for detecting the beta-tubulin gene of the trichomonad is assembled. According to the invention, the detection requirements of parasitic biology and life science researchers can be met, the gene level detection of the pathogen and the research progress of the pathogenic mechanism of the pathogen can be promoted, and favorable technical support is provided for the research work of gene function research, drug development and the like.
Owner:INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI

Bismuth ferrite and barium titanate-based ceramic with high energy storage density and high power density and preparation method thereof

The invention discloses bismuth ferrite and barium titanate-based ceramic with high energy storage density and high power density and a preparation method of the bismuth ferrite and barium titanate-based ceramic. According to the preparation method, a 0.67BiFeO3-0.33BaTiO3 system ferroelectric material is used as a basis, a bismuth layered material BaBi2Nb2O9 is doped into bismuth ferrite and barium titanate-based ceramic according to a certain molar ratio, a novel energy storage ceramic material with high energy storage density and high power density is prepared by adopting a solid-phase synthesis method, the chemical composition of the ceramic material is (1-x)(0.67BiFeO3-0.33BaTiO3) -xBaBi2Nb2O9, and x is greater than or equal to 0.02 and less than or equal to 0.1. According to the obtained energy storage ceramic material, the main performance parameters can be as follows: the energy storage density Wrec is 3.09 J / cm<3>, the energy storage efficiency eta is 85.6%, the power densityPD is 27.2 MW / cm<3> in a 100kV / cm electric field, and the current density can reach 543.95 A / cm<2>. In addition, the preparation process is stable and reliable, the production cost is low, industrialproduction is easy to achieve, and the current lead-free environment-friendly requirement is met. The bismuth ferrite and barium titanate-based ceramic can be widely applied to pulse power systems ofhigh-power microwave weapons, laser weapons, electromagnetic transmitters and hybrid electric vehicles.
Owner:HANGZHOU DIANZI UNIV

A method and system for predicting the relationship between disease and lncRNA

The present invention discloses a method and system for predicting the relationship between disease and LncRNA, comprising: obtaining LncRNA-miRNA-related relationship and miRNA-disease relationship from a known database, and constructing a LncRNA-miRNA-disease interaction network based on the two; LncRNA-miRNA-disease interaction network, construct disease super-expression profile and LncRNA super-expression profile; according to disease super-expression profile and LncRNA super-expression profile, use LncRNA similarity calculation and disease similarity calculation based on RBF neural network, train A prediction model for the association between disease and LncRNA; use the prediction model to predict the LncRNA-disease association pair of candidate samples. The present invention provides further experimental verification of the most promising LncRNA disease association, can effectively mine potential disease-related LncRNAs from massive biological data, reduce the cost and overhead of biological experiments, and accelerate the research progress in the field of bioinformatics.
Owner:CHANGSHA UNIVERSITY

A Method for Identifying Kinetic Chain of Granular System

The invention belongs to the technical field of granular system power transmission chain identification, and relates to a method for identifying a granular system power transmission chain. The method includes the steps that firstly, a granular system is loaded, and granular system images before and after deformation are collected to be used as an original image and a target image respectively; then, the original image and the target image are analyzed, and after a displacement field and a strain field in the granular system surface of the target image at the corresponding moment are obtained, the stress of each point is obtained according to the strain of each point in the strain field; afterwards, image edge detection is conducted on the target image, granular centroids are identified, the coordinates of the granular centroids and the position coordinates of contact points of all granules are read, a force equilibrium and torque equilibrium equation is established for each granule, and the size and orientation of contact force at different contact points on all the granules are acquired through calculation; at last, the contact force of each granule is drawn, and the graph which is continuously represented by the contact force between adjacent granules is the path of the power transmission chain. The method is simple, scientific in principle, convenient and flexible to use, high in practicability, large in development prospect and wide in applied range.
Owner:QINGDAO TECHNOLOGICAL UNIVERSITY

Actinobacillus succinogenes gene knock-out method

ActiveCN107916247AAchieve a traceless knockoutPromote research progressBacteriaMicroorganism based processesDonor strainTransformation efficiency
The invention discloses an actinobacillus succinogenes gene knock-out method. The method comprises the following steps: constructing left and right homologous arms of target genes; constructing suicide plasmids with antibiotic screening markers and negative screening markers; connecting the left and right homologous arms of target genes with the suicide plasmids, transferring into donor strain competent cells, screening accurate positive mono-clones by virtue of resistant spread-plate, and performing sequencing validation; and transferring the accurate positive mono-clones into objective strains actinobacillus succinogenes, screening single-crossing-over positive mono-clones in the resistant spread-plate, and performing negative screening on the positive mono-clones subjected to accurate single-crossing-over, thereby obtaining the recombinant strain with target gene deletion. The method disclosed by the invention is specified at actinobacillus succinogenes gene knock-out genes, and issimple in operation, high in conversion rate, applicable to multi-gene knock-out and capable of realizing non-trace knock-out of the target genes.
Owner:NANJING UNIV OF TECH

Cholesterol pyrophosphate, and preparation method and use thereof

The invention discloses a cholesterol pyrophosphate, and a preparation method and a use thereof. Cholesterol and pyrophosphate are connected through click chemistry, and the targeting auxiliary material cholesterol pyrophosphate (PPi-Chol) having strong affinity to bones is prepared through combining the wide application of the cholesterol in a medicinal preparation with the bone targeting property of the pyrophosphate, so the studying process of the bone targeting dosage form is greatly improved, and the therapy effect of bone related diseases is improved.
Owner:SOUTHWEST MEDICAL UNIVERISTY

Nucleic acid molecule, PCR primer pair and kit for detecting poultry trichomonad TBP gene

The invention discloses a nucleic acid molecule, a PCR primer pair and a kit for detecting a poultry trichomonad TBP gene. Through extensive research, the inventor clones in poultry trichomonad to obtain a poultry trichomonad TBP full-length gene coding sequence as shown in SEQ ID NO: 1, and further designs by utilizing the TBP full-length gene coding sequence to obtain a PCR primer pair capable of detecting the poultry trichomonad TBP gene and the transcriptional level of the poultry trichomonad TBP gene and corresponding PCR reaction conditions. Further, the kit for detecting the poultry trichomonad TBP gene is assembled, so that the detection requirements of parasitic biology and life science researchers can be met, the gene level detection of the pathogen and the research progress of transcriptional regulation signals of the pathogen are promoted, and favorable technical support is provided for the research work of gene function research, drug development and the like. The PCR primer pair is high in repeatability, strong in specificity and high in sensitivity, and does not have amplification signals for non-target genes.
Owner:INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI

Hexa-coordinate chiral dysprosium single-ion magnet with electromagnetic coupling effect and synthesis method thereof

The invention relates to a hexa-coordinate chiral dysprosium single-ion magnet with an electromagnetic coupling effect, the chemical formula of which is represented by [Dy(Cl)3(L)2C2H5OH].C2H5OH, wherein L is tricyclohexylphosphine oxide, and the central ion of the chiral dysprosium single-ion magnet is located in a hexa-coordinate octahedral coordination environment. With dysprosium chloride hexahydrate as metal salt, L as tricyclohexylphosphine oxide and ethanol and water as mixed solvent, the hexa-coordinate chiral dysprosium single-ion magnet is prepared by stirring, separation and solid washing. The advantages of the hexa-coordinate chiral dysprosium single-ion magnet are as follows: the chiral single-ion magnet with the electromagnetic coupling effect is prepared by the simple chemical synthesis process for the first time, and the single-ion magnet can show a slow magnetic relaxation behavior and an electromagnetic coupling behavior at the same time. Such a material with the electromagnetic coupling effect can greatly increase nonvolatile information storage density, helps to enhance and improve the performance of non-silicon-based electronic devices, and is expected to promote the progress of research on multiferroic materials.
Owner:NANKAI UNIV

A Method for Storage and Compensation of Molten Carbonate Fuel Cell Electrolyte

The invention relates to a molten carbonate fuel cell electrolyte storage and compensation method. The method comprises the following steps: 1. preparing an electrode and a diaphragm as required, wherein the porosity of the electrode is 60-80% and the porosity of the diaphragm is 50-60%; 2. calculating the masses of Li2CO3 and K2CO3 molten salt electrolytes with molar ratio of 62 to 38 in a pore, required by the prepared electrode and the diaphragm after completely roasting; 3. fully and uniformly mixing the molten salt electrolytes after mass calculation, drying, and uniformly spreading the molten salt electrolytes on the electrode and the diaphragm respectively; 4. putting the electrode and the diaphragm with the molten salt electrolytes into a muffle furnace for roasting for 10-20h at 480-540 DEG C, storing the electrolytes required by the molten carbonate fuel cell in the electrode and the diaphragm, wherein the electrolytes stored in the electrode can compensate the diaphragm during cell running, so that the cell can run stably. The method is easy to operate and has the important significance on electrolyte storage and compensation of the improved molten carbonate fuel cell.
Owner:HUANENG CLEAN ENERGY RES INST

Feeding machine device and accurate feeding system

The invention provides a bait casting machine device and a precise bait casting system. The bait casting machine device comprises a machine body; the feed box is arranged above the machine body and is in butt joint with a feed opening in the machine body, a bait metering device is arranged in the feed opening, and the bait metering device is driven to turn over based on a first motor; the first end of the flow guide groove is arranged right below the discharging opening, the second end of the flow guide groove is connected with the throwing disc, the flow guide groove is a straight flow groove, and the first end and the second end are set to be higher than the second end; the throwing disc is driven to rotate based on a second motor, so that the bait on the throwing disc obtains centrifugal acceleration and is finally thrown out in the radial direction of the throwing disc. Traditional manual feeding can be replaced, traditional manual labor intensity is reduced, equipment works continuously, and inconvenience and danger of manual feeding are reduced.
Owner:DALIAN OCEAN UNIV

Accelerant for improving dry weight of euglena gracilis, euglena gracilis culture medium and application of euglena gracilis culture medium

The invention provides an accelerant for improving the dry weight of euglena gracilis, an euglena gracilis culture medium and application of the euglena gracilis culture medium, and belongs to the technical field of euglena gracilis culture. The accelerant is selected from one or more of choline, ectoine, vitamin B1 and sulfadiazine. The accelerant is added into a culture medium for euglena gracilis culture to promote dry weight increase of euglena gracilis, biomass efficient output and sustainable culture of euglena gracilis are achieved, research progress of an existing euglena gracilis culture productivity mechanism can be promoted, and the bottleneck problem faced by large-scale euglena gracilis culture is solved.
Owner:SHENZHEN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products