The invention discloses a PVC-U drainage pipe fitting and its preparation method and application. The use of an environmentally friendly lead-free heat stabilizer, ultrafine nano-active calcium carbonate, and a composite high-efficiency environmental-friendly nano inorganic antibacterial and anti-mildew modifier component improves PVC-U. The performance of U drainage pipe fittings, the pipe fittings are not easy to migrate, precipitate, and change color, and the smoothness and brightness of the appearance of the pipe fittings have been significantly improved, the flow resistance is small, and they have good physical and mechanical properties of wear resistance and impact resistance; the pipe fittings have excellent Hydrophobic performance, smooth and flat surface, low interface free energy, difficult to adhere to the carrier and sediment, so that the pipe fittings have strong anti-fouling ability, small flow resistance, not easy to scale, discoloration, longer service life; antibacterial and anti-mildew effect Durable, safe and efficient, the pipeline system is not easy to block, and the pollution of water quality by mold is avoided.