1769 results about "Aerosolize" patented technology

A new dry powder inhaler is developed as a pulmonary medicine delivery device for dispersing precise tiny dosages (10 μg-50 mg) of pure carrier-free ultra-fine powdered medicament (<5 μm aerodynamics particle size) into a patient's lung. The powder is drawn from the blister cell and dispersed through an outlet tube assisted by two air streams. The first air stream goes through a the blister cell from its upstream side, to significantly fluidize the medicament in the dose to flow upward. The second one extracts the fluidized powder from downstream of the blister cell for further deagglomeration and dispersion of the medicament powder by shear force. The rotating multi-dose blister can hold up to 60 doses, which are pre-metered with pure ultra-fine powdered medicament. So that it has higher drug loading capability in small volumes, compared to most current dry powder inhalers, which usually use some excipient. The inhaler efficiently disperse the aerosolized medicament in the air stream to the deep interior of patient's lung. The fine particle fraction (<4.7 μm) is reported to reach as high as 80% using this inhaler.

The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of upper and/or lower airway passages and/or lungs, e.g., allergic rhinitis and asthma is disclosed.

The invention is an inhaler for aerosolization of medicament with a unique dosage counter. The dosage counter has a first and second counting ring and a coupling device that interconnects the counting rings. The counter being advanced by a unique armature mechanism that is interconnected with the actuation mechanism of the inhaler to insure accurate counting of doses.

A method of creating small particles by a technology referred to here as “violent focusing” is disclosed, along with devices for generating such violent focusing. In general, the method comprises the steps of forcing a first fluid out of an exit opening of the feeding channel to create a fluid stream. The exit opening is positioned such that the fluid flowing out of the channel flows toward and out of an exit orifice of a pressure chamber which surrounds the exit opening of the feeding channel, and is filled with an atomizing fluid. An atomizing fluid such as a gas is directed towards the first fluid stream in approximately orthogonal directions and surrounding the circumference of the first fluid stream from all sides. The first fluid flow is broken into particles which have dimensions which are smaller than the dimensions of this fluid stream.

A non-burning type flavor inhaler includes an aerosol source that generates an aerosol; an atomizer that atomizes the aerosol source without burning; a power source that supplies power to the atomizer; a light-emitting element; and a control unit that controls the light-emitting element. The control unit controls the light-emitting element in a first light-emitting mode in a puff state inhaling the aerosol, and controls the light-emitting element in a second light-emitting mode different from the first light-emitting mode in a non-puff state not inhaling the aerosol. The second light-emitting mode changes according to a number of puff actions for inhaling the aerosol.

The present invention provides an improved means of treating tracheobronchitis, bronchiectasis and pneumonia in the nosocomial patient, preferably with aerosolized anti gram-positive and anti-gram negative antibiotics administered in combination or in seriatim in reliably sufficient amounts for therapeutic effect. In one aspect, the invention assures this result when aerosol is delivered into the ventilator circuit. In one embodiment the result is achieved mechanically. In another embodiment, the result is achieved by aerosol formulation. In another aspect, the invention assures the result when aerosol is delivered directly to the airways distal of the ventilator circuit. The treatment means eliminates the dosage variability that ventilator systems engender when aerosols are introduced via the ventilator circuit. The treatment means also concentrates the therapeutic agent specifically at affected sites in the lung such that therapeutic levels of administrated drug are achieved without significant systemic exposure of the patient to the drug. The invention further provides a dose control device to govern this specialized regimen.

The invention discloses a spray evaporation treatment method of the wet method flue gas desulfurization wastewater in a thermal power station. In the method, an atomizing nozzle is arranged in the region with the temperature at 413-470 K and the flue gas speed of 5-11 m/s in a flue of the boiler tail part; desulfurization wastewater is pumped by utilizing a water pump, air is compressed by a compressor, and the pressure ratio of the compressed air to the desulfurization wastewater entering into the atomizing nozzle is 0.25-0.6; the speed of liquid droplets atomized by the atomizing nozzle is 50-80 m/s, and particle diameters of the liquid droplets are less than 50 mu m; and the liquid droplets are evaporated and then exhausted out of a chimney together with the flue gas. The invention can save chemical drugs utilized in the conventional wastewater treatment method; overcome the defects of many apparatuses, large investment, high running cost and heavy apparatus repair and maintenance load of a wastewater treatment system in the prior art, overcome the great corrosion influence of chlorine ions in water meta-acidity environment, reduce the specific resistance of ashes in a dust collector and improve the dust collector efficiency through increasing the flue gas humidity and properly lowering the flue gas temperature.

The invention is a low viscosity oil-in-water emulsion that is readily atomizable for use in cosmetic and dermatological applications and particularly for spray or aerosol applications. The oil-in-water emulsion includes at least one phospholipid and at least one oil-in water emulsifier. In some embodiments, the emulsion may also include a water-in-oil emulsifier. The invention also includes a process for preparing the emulsion.

The portable device (100, 200, 300, 400) for inhalation of at least one active composition comprises:

• • at least one reservoir (105, 110, 205) for storing an active composition,
  • an intermediate chamber (115) connected to at least one reservoir,
  • an inhalation line (120) connected to the intermediate chamber,
  • a means (130, 135, 230) for aerosolising the active composition coming from a reservoir, and
  • a regulator (125, 225, 325, 405, 410) for regulating the quantity of aerosolised active composition according to a command representing a quantity of active composition to be aerosolised received by the regulator.

Hemophilia treatment by the inhalation of coagulation factors. Dry powder Factor IX is aerosolized to a mass median aerodynamic diameter of 4 μm or less, with at least 90% monomer content, at least 80% activity level, and 10% water or less. The aerosol is slowly, and deeply inhaled into the lung, and followed by a maximal exhale.