129results about How to "Minimize absorption" patented technology

The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of upper and / or lower airway passages and / or lungs, e.g., allergic rhinitis and asthma is disclosed.

An electro-optic display comprising at least two separate layers of electro-optic material, with one of these layers being capable of displaying at least one optical state which cannot be displayed by the other layer. The display is driven by a single set of electrodes between which both layers are sandwiched, the two layers being controllable at least partially independently of one another. Another form of the invention uses three different types of particles within a single electrophoretic layer, with the three types of particles being arranged to shutter independently of one another.

This invention relates to a composition of a non-labeled monoclonal antibody binding to a tumor antigen and a second monoclonal antibody labeled with a NIR fluorescence label, binding to the same tumor antigen, wherein the first and second antibody exhibit no cross reactivity. The composition can be used for the treatment of patients suffering of solid tumors which are associated with an overexpression of such a tumor antigen. The invention further relates to a the co-administration of said first and second antibody as wells as to a method of acquiring a NIR fluorescence images of such tumors or the patients suffering from such tumors during the treatment of said patient with such composition.

Biodegradable polymeric microparticle compositions containing one or more active agents, especially those useful for treating or preventing or one or more diseases or disorders of the eye, and methods of making and using thereof, are described. The microsphere compositions release an effective amount of the one or more active agents for a period greater than 14 days in vivo, preferably greater than 60 days in vivo, more preferably up to 73 days in vivo, more preferably greater than 90 days in vivo, even more preferably over 100 days in vivo, and most preferably greater than 107 days in vivo. In a preferred embodiment, the microparticle compositions contain one or more active agents such as AG1478 to induce nerve regeneration, specifically regeneration of the optic nerve useful for managing elevated intraocular pressure (TOP) in the eye.

A hybrid optoelectronic device and method of producing the hybrid device in which the hybrid device includes a substrate with an input region configured to accept input light, a sol-gel glass multimode interference region coupled to and contiguous with the input region and configured to accept and replicate the input light as multiple self-images, and a sol-gel glass output region contiguous with the multimode region and configured to accept and to output the multiple self-images. Alternatively, the hybrid optoelectronic device includes a substrate with a photoelectronic device, a surface resonator including a light-emitting part of the photelectronic device and configured to resonate light from the photoelectronic device to produce a laser light, and a grating outcoupler contiguous with the surface resonator and configured to diffract the laser light outward from the grating outcoupler and to electrically vary an index of refraction of the outcoupler and change a direction of the diffracted laser light.

Biodegradable polymeric microparticle compositions containing one or more active agents, especially those useful for treating or preventing or one or more diseases or disorders of the eye, and methods of making and using thereof, are described. The microsphere compositions release an effective amount of the one or more active agents for a period greater than 14 days in vivo, preferably greater than 60 days in vivo, more preferably up to 73 days in vivo, more preferably greater than 90 days in vivo, even more preferably over 100 days in vivo, and most preferably greater than 107 days in vivo. In a preferred embodiment, the microparticle compositions contain one or more active agents useful for managing elevated intraocular pressure (TOP) in the eye. In one embodiment, the microspheres are formed from polylactide-co-glycolide (“PLGA”); in another embodiment, the microspheres are formed from a blend PLGA and poly lactic acid (“PLA”). Relatively hydrophilic, and preferably carboxylated, polymeric materials such as PLGA are used for a drug such as timolol maleate, which is relatively water soluble, to increase drug loading. Higher molecular weight polymers, as well as the ratio of LA (which has a longer degradation time, up to one to two years) to GA (which has a short degradation time, as short as a few days to a week), are used to provide release over a longer period of time. The combination of drug loading and release rate, as well as the minimization of initial burst release, result in prolonged release of a higher amount of drug.

A system, including a particulate matter analyzer and collecting filter, provides a method of analyzing and collecting samples from fluids, such as collecting particulate matter from air. A mass measuring unit and composition analyzing unit can be provided for either simultaneous or immediately consecutive measurements within a single instrument. The filter material can have an antistatic electricity characteristic and can be impregnated with reference material to enable calibration of the composition analyzing unit.

The present invention provides bariatric therapy systems. One system includes a gastrointestinal implant device and a delivery mechanism therefor. The device can include a sleeve for placement into a small intestine and to minimize absorption of nutrients by its walls. An anchoring mechanism coupled to a proximal end of the sleeve and designed to be secured within the stomach can be provided. A passageway extending through the anchoring mechanism and the sleeve can also be provided, along which food can be directed from the stomach to the small intestine. The delivery mechanism can include a housing for accommodating the device, and a deploying balloon situated within the housing and which can be actuated to direct the sleeve of the device from within the housing to the site of implantation. Methods for providing bariatric therapy are also provided by the present invention.

A process for cooking a food in oil and / or fat is provided. A dry protein mixture, a dry alkaline protein mixture, an aqueous alkaline protein mixture or an aqueous acidic protein is added to a food prior to cooking. The dry protein mixture, dry alkaline protein mixture, aqueous alkaline protein mixture and aqueous acidic protein solution comprise myofibrillar proteins and sarcoplasmic proteins substantially free of myofibrils and sarcomeres. The amount of oil and / or fat absorbed by the food during cooking is substantially reduced.

An elongate batten (1) adapted for positioning intermediate an inner wall framing member (2) and an outer wall cladding sheet (3) to facilitate dispersion and evaporation of moisture from a wall cavity. The batten includes at least one channel to facilitate migration and drainage of moisture between the batten and the framing member.

An imaging tube (12) includes a cathode (30) that emits an electron beam (32) and an anode (38). The anode (38) includes multiple target surfaces (36). Each of the target surfaces (36) has a focal spot that receives the electron beam (32). The target surfaces (36) generate multiple x-ray beams (42) in response to the electron beam (32). Each x-ray beam (42) is associated with one of the target surfaces (36). An x-ray imaging system (10) includes the cathode (30) and the anode (38). A controller (28) is electrically coupled to the cathode (30) and adjusts emission of the electron beam (32) on the anode (38).

An optical filtering structure comprising a stack of layers forming a first filter letting pass a first spectral band, and a second filter adjacent to the first filter and which lets pass a second spectral band comprising:a plurality of dielectric layers common to the two filters and of different refractive indices;n first metal layers common to the two filters;m second metal layers arranged only in the second filter;and wherein at least one of said dielectric layers comprises, in the first filter, a thickness different to that in the second filter, and / or wherein at least one dielectric layer is arranged only in the second filter;n being an integer greater than or equal to 0, and m being an integer greater than or equal to 1.

A lithographic projection apparatus includes a radiation system constructed and arranged to supply a projection beam of radiation, a support structure constructed and arranged to support a patterning structure, the patterning structure constructed and arranged to pattern the projection beam according to a desired pattern, a substrate support constructed and arranged to support a substrate, and a projection system constructed and arranged to project the patterned beam onto a target portion of the substrate. The apparatus further includes a gas flushing system comprising radial gas flow outlets, said gas flushing system being constructed and arranged to generate a radial gas flow through said radial gas flow outlets in an intermediate space defined between said gas flushing system and said substrate, wherein the radial gas flow has a radial velocity directed outwards in said space with a magnitude larger than zero at every location in said space.

The present invention provides a method of minimizing absorption of visible light in an ink composition comprising an IR-absorbing macrocyclic cyanine dye, comprising preselecting said dye such that it includes at least one moiety for reducing intermolecular interactions between adjacent dye molecules. The method is especially suitable for use in connection with netpage and Hyperlabel systems.

A polymer comprising repeat units of formulae (1) to (3) increases a dissolution rate in an alkali developer under the action of an acid. R1, R2 and R5 are H or CH3, R3 and R4 are H or OH, and X is a tertiary alkyl group having an adamantane structure. A resist composition comprising the inventive polymer has a sensitivity to high-energy radiation, improved resolution and minimized proximity bias and lends itself to micropatterning with electron beams or deep UV for VLSI fabrication.

A panel light source device comprises a light source, a U-shaped reflector surrounding the light source, a light guide, and a plurality of metal grid wires. The light guide has an incoming surface facing the light source and an outgoing surface. The light is transmitted into the light guide from the incoming surface and then transmitted out of the light guide from the outgoing surface. The metal grid wires are disposed between the incoming surface and the light source for transmitting the light with a predetermined polarization therethrough and reflecting the rest light therefrom.

A tuneable laser having an active section, a phase section and a Bragg reflector comprising a plurality of discrete grating units, at least two of which gratings have a different pitch, wherein current is applicable to at least the grating having a longer pitch, such that the effective wavelength of the grating having a longer pitch can be tuned to the wavelength of the grating having a shorter pitch. A chirp grating can provide the difference in pitch.

Novel compounds having a functionalized group capable of binding to a solid substrate; a photoactivatable group capable of generating a reactive group upon exposure to light and being for binding a screenable moiety; and a polymer capable of forming a monolayer on a solid substrate, and having the functionalized group and to the photoactivatable group attached thereto and processes for the preparation thereof are disclosed. Further disclosed are arrays of screenable moieties (e.g., nucleic acids, proteins, carbohydrates, substrates, chelating agents and many more) prepared using these novel compounds.

The present invention provides an IR-absorbing macrocyclic cyanine dye, wherein said dye comprises at least one moiety for reducing intermolecular interactions, thereby minimizing absorption of visible light.Dyes of this type are especially suitable for use in netpage and Hyperlabel systems.

A packed phosphor screen or panel consisting of at least one flat square or rectangular screen or panel, optionally packed apart in a wrapper foil, and a sealed package, wherein said package is layered in form of an asymmetrical barrier layer foil, said foil comprising an inner flexible thermoplastic polymer layer and an outer polymer layer in adhesive contact with an aluminum layer situated inbetween said inner flexible thermoplastic polymer layer and said outer polymer layer, wherein said foil is characterized by adhesive forces, between said outer polymer layer and said aluminum layer, of more than 2.5 N / mm<2 >following DIN 53 357, by a permeation to water vapor of less than 0.01 g per sq.m. in an environment having a temperature of 23° C. and a relative humidity of 75% RV for 24 hours following DIN 53 122, and by a permeation of less than 0.01 cm<3 >per sq.m. per 24 hours and per bar for each of oxygen, carbon dioxide and nitrogen following DIN 53 380 (ISO 2556, ASTM D 1434).

A semiconductor package includes: a semiconductor chip having a first surface, and a second surface that is opposite to the first surface and allows a semiconductor device to be formed thereon; bonding pads disposed on the second surface of the semiconductor chip; and a metal ion barrier layer disposed on the first surface of the semiconductor chip, and preventing metal ions from penetrating into the semiconductor chip through the first surface of the semiconductor chip. Accordingly, the semiconductor package can obtain a superior semiconductor device by minimizing moisture absorption and effectively blocking the penetration of metal ions.