423results about How to "Highly toxic" patented technology

The invention is environmental-friendly waterborne nanometer fireproof flame-retardant coating and the preparation method, which belong to the fireproof flame-retardant coating manufacturing industry. The flame-retardant coating is obtained through the compounding of two types of flame-retardant agents, waterborne resin, ammonium polyphosphate, melamine, carbon-forming agent, nanometer pigment and filler, micrometer pigment and filler and other auxiliary agent; the flame-retardant coating contains no organic agent and halogen flame retardant, low VOC content, good fireproof property, good physical and chemical properties; the composition of the flame-retardant coating is as follows: the content of waterborne resin is 10-90%; the content of phyllo-silicate nanometer flame retardant which contains phosphor, nitrogen organic intercalation is 1-50%; the content of nanometer magnesium hydroxide flame retardant wrapped by polymer is 1-50%; the content of ammonium polyphosphate is 1-30%; the content of melamine is 1-20%; the content of carbon-forming agent is 1-30%; the content of nanometer pigment and filler is 0.1 to 30%; the content of micrometer filler is 0.1 to 60%; the content of dispersant is 0.1 to 10%; the content of stabilizer is 0.1 to 10%; the content of water is 0.1 to 50%; the content of micrometer pigment is proper; firstly, waterborne resin, nanometer flame retardant, ammonium polyphosphate, melamine, carbon-forming agent, nanometer pigment and fillers, dispersant and stabilizer are put into a planet stirring reactor for stirring and even dispersion; micrometer pigment and filler, water, dispersant and stabilizer are added to the discharged mixture and then put into a high-speed dispersion machine for even dispersion so that the product is obtained.

The invention provides a method for improving the gene targeting efficiency and a method for carrying out in-situ repair on the base on a beta-globulin gene locus. The method for improving the gene targeting efficiency comprises the following steps of: S10, determining a gene locus to undergo in-situ repair; and S20, introducing a CRISPR / Ca system to cleave editing lotus DNA to cause DNA damage and simultaneously providing a repair template segment. Based on the deficiency of existing gene modification, the gene modification efficiency, the timeliness and the modification quality are improved after single-stranded oligonucleotides (ss ODNs) and a small molecule compound participate in a CRISPR / Cas9 gene modification system.

The invention discloses a method for preparing a nanosilver / nano silicon dioxide-containing antibacterial biological dressing, and relates to the field of antibacterial biological dressings. The nanosilver / nano silicon dioxide-containing antibacterial biological dressing is prepared by adding mixed solution of chitosan and polyvinyl alcohol and silver-carried silicon dioxide powder during the acetalation of the polyvinyl alcohol. The nanosilver / nano silicon dioxide-containing antibacterial biological dressing of the invention can accelerate the wound healing, slowly release the silver nanoparticles and continuously act on reproductive bacteria, has the characteristic of durable and high-efficiency sterilization and does not produce medicament resistance; and through the researches on the toxicity of the material to mouse fibroblast cells, the product does not produce obvious toxicity to the cells but promotes the growth of the cells.

The present invention is directed to nucleic acids encoding glycosyltransferases, the proteins encoded thereby, and to methods for synthesizing oligosaccharides using the glycosyltransfereses of the invention. In particular, the present application is directed to identification a glycosyltransferase locus of Neisseria gonorrhoeae containing five open reading frames for five different glycosyltransferases. The functionally active glycosyltransferases of the invention are characterized by catalyzing reactions such as adding Gal β1→4 to GlcNAc or Glc; adding GalNAc or GlcNAc β1→3 to Gal; and adding Gal α1→4 to Gal. The glycosyltransferases of the invention are particularly suited to the synthesis of the oligosaccharides Galβ1→4GlcNAcβ1→3Galβ1→4Glc (a mimic of lacto-N-neotetraose), GalNAcβ1→3Galβ1→4GlcNAcβ1→3Galβ1→4Glcβ1→4 (a mimic a ganglioside), and Galα1→4Galβ1→4Glcβ1→4Hep→R (a mimic of the saccharide portion of globo-glycolipids).

The invention relates to an additive used for monocrystalline silicon wafer alkaline flocking and an application method thereof, belonging to the technical field of solar batteries. The additive is prepared by the following components: ethanolamine, polyphosphate, sodium dodecylbenzene sulfonate, sodium hydroxide and water. A flocking agent is prepared through the following steps: (1) dissolving sodium hydroxide in deionized water so as to obtain alkaline flocking liquid; (2) adding the additive motioned above into the alkaline flocking liquid to obtain the flocking agent. During flocking, monocrystalline silicon wafers used for solar batteries are immersed in the flocking agent with temperature controlled to be 75 to 85 DEG C and flocking time controlled to be 15 to 18 minutes. The additive used for monocrystalline silicon wafer alkaline flocking in the invention enables flocking reaction time to be shortened and productivity to be enhanced; prepared texture surface pyramids have a uniform size and low reflectivity; the additive is applicable to solar battery silicon wafer alkaline flocking of different specifications and meets the purpose of industrial production.

The invention discloses a method for quickly screening and detecting azo dyes forbidden in textile materials, leathers and dyes using gas chromatography mass spectrometry, which comprises the following steps: 1) preparing a sample, 2) subjecting the sample to reduction reaction, 3) extracting the sample, 4) performing the gas chromatography mass spectrometry on the sample, 5) screening decision: compared with the GC-MS analysis result of a standard solution, if the retention time and the mass spectrum of the aromatic amine in the sample keep with standards, the sample is judged as a suspicious positive sample, otherwise it is a negative sample and directly judged as a qualified sample. The sample pre-treatment time is shortened, the cost is reduced, the detection time is shortened, the operation step is simple, the operation is convenient, the operation time is short, the operation cost is low, the detection efficiency is improved; the aromatic amine in the sample is detected by a gas chromatography mass spectrometer, color interference problem is not existed, the sample matrix is effectively prevented from being infected, and the judgment accuracy is high, thus the method is not only suitable for textile materials, but also suitable for other products such as leathers and dyes.

The invention provides a preparation method of highly dispersive spindle-shaped nano titanium dioxide sol. The method comprises the following steps: adding ammonia with mass concentration being 10%-50% into aqueous solution containing titanyl sulfate, adjusting pH value to be 7.5-11; stirring and reacting for over 4 hours to obtain white precipitation, washing by deionized water and centrifugating for several times; mixing the white precipitation with the deionized water, adjusting pH value to be 1-7, stirring for over 2 hours to obtain highly dispersive spindle-shaped nano titanium dioxide sol. The invention improves traditional low-temperature synthesis technology, and the dispersibility of the prepared product is greatly improved; the spindle-shaped nano titanium dioxide has better biocompatibility and good biological security, and the invention has simple preparation method and low cost and is beneficial for industrialized production.

The invention relates to a preparation method of a polymer weak gel deep profile control agent. The preparation method comprises the following steps of preparing sodium carboxymethyl cellulose and distilled water into sodium carboxymethyl cellulose water solution of which the mass percentage is 1%-2%; adding acrylamide of which the mass is 2-8 times as great as that of the sodium carboxymethyl cellulose into the sodium carboxymethyl cellulose water solution, and then adding a cross-linking agent which accounts for 0.01%-2% of the total weight of the sodium carboxymethyl cellulose and the acrylamide; enabling nitrogen to enter into a closed system and isolating the air, and adding an initiating agent which accounts for 1%-2% of the total mass of the sodium carboxymethyl cellulose and the acrylamide; and discharging after carrying out constant-temperature reaction for 4-12 hours under the temperature of 30-60 DEG C. According to the preparation method disclosed by the invention, the acrylamide is grafted to the sodium carboxymethyl cellulose, polymer weal gel with a mesh structure is formed under the action of the initiating agent and the cross-linking agent, and a polymer weak gel system integrates the advantages of the sodium carboxymethyl cellulose and the acrylamide.

Provided is a pharmaceutical composition for treating or preventing glaucoma, comprising a pyridylamino acetic acid compound represented by general formula (1) or a pharmacologically acceptable salt thereof as an active ingredient. In formula (1), R1, R2, and R3 each independently represent a hydrogen atom or the like; Y represents a group: -Q1-Q2 (wherein Q1 represents an arylene group or the like; and Q2 represents a group such as an aromatic ring group which may be substituted by a halogen atom or the like) or a dicyclic heteroaromatic ring which may be substituted by a halogen atom or the like; and Z represents a group such as an aromatic ring group which may be substituted by a halogen atom or the like.

The invention discloses a preparation method of a chitosan / polyvinyl alcohol sponge dressing containing nano-silver. The invention relates to an antibacterial dressing for therapy of trauma, and the chitosan / polyvinyl alcohol sponge dressing containing the nano-silver is prepared by adding nano-silver / polyvinyl alcohol solution and polyvinyl alcohol / chitosan blend solution. The obtained dressing has good biocompatibility and hemostatic and antibacterial effects, and can promote the wound healing; the product can accelerate the wound healing, release nano-silver particles in a sustained manner, be acted on regenerated bacteria constantly, have the lasting and high-efficient sterilization characteristics and avoid the drug resistance during the wound treatment process; the research on the toxic effect of the material to mouse fibroblasts shows that the product has no obvious toxicity to the cells and has the effect of promoting the growth of the cells; and preparation method has simple process equipment and low price of experimental raw materials and is conductive to industrialization.

The invention provides a red fluorescence gold nanocluster as well as a preparation method and an application thereof and belongs to preparation and applications of fluorescence nano materials. According to the preparation method, cheap egg white is used for rapidly reducing and coating HAuCl4, and gold nanocluster AuNCs@EW giving red fluorescence is synthesized. The preparation method is simple, rapid and low in cost. The prepared nanocluster can be used as fluorescent dye, can be used for detecting mercury ions and further can be used for detecting GSH (glutathione).

The invention belongs to the technical field of chemical engineering synthesis, and particularly relates to a preparation method of biologically degradable thermoplastic polyurethane elastomer. According to the invention, a simple one-stage method is adopted, and polymer polyol, diisocyanate, and a chain extender are used to synthesize the biologically degradable thermoplastic polyurethane elastomer. The synthesized elastomer keeps excellent mechanical property, wear resistance, oil resistance, high strength, high modulus and other performance, and has the prominent characteristic of being able to achieve auto-biodegradation for a proper duration or under a proper natural environment, so that no toxic material or pollution is generated, and the pollution of the environment by the waste material is effectively avoided. The preparation method can overcome the defects of long degradation period in the conventional aliphatic polyester TPU and of high manufacturing cost in polycaprolactone TPU, and is widely applied to various fields.

The invention discloses an advanced redox innocent treatment system and method for waste pollutants, belonging to the technical fields of pollution treatment and restoration and environmental protection. The innocent treatment system comprises a waste degradation subsystem, a waste liquid treatment subsystem, an ozone water preparation subsystem, a degradation reagent addition subsystem, a detection control subsystem and a water level control subsystem. The method comprises the following steps: determining the type of waste pollutant, selecting the degradation reagent, pouring the waste pollutant into a treating pond, carrying out advanced redox treatment on the waste pollutant, carrying out innocent treatment on the treated waste liquid, reutilizing, and carrying out biodegradation treatment on the treated soil. The system and method have the advantages of obviously higher degradation efficiency and short time consumption, can treat organic pollutants within 2-3 days, can treat heavy metal pollutants within 3-5 days, greatly shorten the pollutant treatment time, and lower the cost by more than 70%.

The invention discloses a novel binary metal composite perovskite material and a preparation method thereof, and also an application method of the novel binary metal composite perovskite material to preparation of perovskite solar cells with various structures. The material is prepared from halogenated methylamine, lead halide, strontium halide and a solvent. Compared with conventional CH3NH3PbI3 perovskite materials, the material has the advantages that the content of lead ions is reduced, environment protection is facilitated, and a good basis is laid for large-scale commercialization of perovskite solar cells.

Device and method for disinfection of ice machines, ice silos, and / or chutes for transport of the ice, with a storage tank (8) for holding a disinfectant, with a pressure line (7) for the supply of pressurized carrier fluid, with at least one atomizer device (6) for atomizing the disinfectant and for generating a mixture of carrier fluid and disinfectant and with an inlet for introducing the carrier fluid / disinfectant mixture into the ice machine (1, 19, 23, 28, 32), the ice silo (2, 20, 24, 33), or the ice chutes (4, 21, 29, 34).

The invention discloses a detection method for obligate hydrocarbon oxidizing bacteria, belonging to the technical field of microorganism detection methods. The detection method comprises the following steps of: suspending and diluting a soil sample with a basic culture medium; performing short-term culturing in combination with a selective culture carbon source and an oxidation reduction indicating dye for 3-5 days; and computing the quantity of obligate hydrocarbon oxidizing bacteria in the soil sample according to the color change of an airtight culture tube through a computer program. A detection technology for obligate hydrocarbon oxidizing bacteria disclosed by the invention has the advantages of simple operating process, economic efficiency, practicability, quickly-obtained result in a short period of time, high specificity, capability of effectively shielding the interference of other bacteria on counting and simple and accurate counting process, and is suitable for large-scale industrial exploration measurement with a large sample quantity.

This invention relates to a synthesis method of fatty acids diethanolamine. It takes fatty acid and diethanolamine as raw materials. The method includes follow steps: first fatty acids and a certain amount of diethanolamine for dehydration and condensation reaction, then adding the remaining diethanolamine and alkaline catalyst for aminolysis reaction, the final using activated clay for adsorption treatment, and through filtration to obtain fatty acid diethanolamine. The weight proportion between fatty acids and diethanolamine is 1:0.5 ~ 0.6; account for weight, 30 ~ 70% diethanolamine add in dehydration and condensation reaction, and the remaining add in aminolysis reaction; its alkaline catalyst is one of the alkali metal hydroxide, potassium fluoride and sodium borohydride, account for 0.3 to 2.0% of total weight of fatty and diethanolamine.

The invention discloses an environment-friendly water paint remover for removing a polysiloxane paint, the constituents of which comprise carbonic allyl ester with the proportion of 25 percent to 40 percent, methyl carbonate with the proportion of 10 percent to 20 percent, alkyl pyrrolidone with the proportion of 5 percent to 20 percent, glycol ether with the proportion of 2 percent to 10 percent, micromolecule alkylketone with 3 to 6 carbon atoms and the proportion of 5 percent to 15 percent, an anticorrosive agent with the proportion of 2 percent to 4 percent, a surfactant built with negative ions and non-ions and with the proportion of 1 percent to 2 percent, and with a built mass ratio between an anionic surfactant and a non-ionic surfactant equal to 0.8 : 1 to 1 : 1, a thickener with the proportion of 3 percent to 6 percent, and water with the remained proportion. The remover of the invention has the advantages that the remover can be easily washed after being painted on the surface of basic materials for removing the paint, functioning temperature is normal temperature without the necessity of heating, and an oil-bound film is not formed, thus imposing no impact on a next hull painting. In addition, the remover of the invention contains no strong acid and base, thus having no damage to the surface of metal basic materials.

The invention belongs to the technical field of escherichia coli phage, and particularly relates to a broad-spectrum escherichia coli phage capable of cracking four bacteria and an application of the broad-spectrum escherichia coli phage to sterilization and bacterium prevention. The invention mainly discloses an escherichia coli phage EC35P1 (Escherichia coli phase EC35P1), and the preservation number of the escherichia coli phage EC35P1 is CCTCC M 2020438. The phage is a virulent phage separated from the nature, tests prove that the phage has no toxic effect on normal microbial flora, and DNA of the phage cannot encode virulence genes and is high in stability. The phage is wide in host range, can be used for cracking escherichia coli, shigella, salmonella and enterobacter cloacae, and large-scale industrial production can be realized. The phage provides an excellent strain resource for developing a novel antibacterial preparation, and has a good application and development prospect.

An improved fuel additive formulation, method of use, and method of producing the fuel formulation are described. The improved fuel additive of the present invention comprises a mixture of nitroparaffins (comprising nitromethane, nitroethane, and nitropropane), and a combination of modified commercially available ester oil and / or a solubilizing agent, and / or toluene. The ratio of ester oil and / or solubilizing agent and / or toluence to nitroparaffin is preferably less than 20 volume percent, with nitroparaffins comprising the balance of the additive. A method of preparing and using the additive formulation is also provided.

The invention relates to a composite printing paste and application thereof. The composite printing paste is prepared from the following raw materials in parts by weight: 60-90 parts of modified starch, 2-30 parts of plant gum powder and 0.1-0.6 part of water solube preservative. The composite printing paste has the following application: taking 3-10 parts of composite printing paste and 90-97 parts of water in parts by weight, and uniformly mixing, wherein the optimized parts in part of the raw materials are 4-6 parts of composite printing paste and 94-96 parts of water. The composite printing paste has the advantages that the compounding is reasonable, stable property, the acidity or alkalinity is especially suitable for printing, the paste has good compatibility with other chemicals, and the cost is low; the anti-corrosion property is high, the paste is difficult to nourish bacteria and deteriorate and is suitable for storing for a long term, and the raw paste and printing ink have long preservation time and no toxicity; the anionic paste has good rheological property and ensures good printing property.

The invention relates to an emodin derivative and the application in preparing a anti-cancer drug, and the chemical structural formula of the emodin derivative of the invention is as shown in formula I, wherein, R1, R2, R3 are defined as described in the specification; the emodin and the derivative thereon provided by the invention are compounds which are prepared in a way that natural emodin is taken as the matrix, and then structural modification is carried out in accordance with the principles of drug molecules to design out the highly active compounds; experiments proof that the emodin derivative has obvious inhibitory effect on various tumor cells and can be used in preparing cancer-treatment drugs.

A polyimide fiber with kidney-shaped section and a preparation method thereof belong to the technical field of polyimide fibers. The preparation method includes: utilizing polyamide acid (PAA) solution synthesized by aromatic dianhydride and aromatic diamine to perform the wet spinning process by the aid of circular spinneret holes, adjusting spinning conditions including spinneret speed, composition, proportion and temperature of coagulating bath, the length of hydrazine and the like to obtain a PAA as-formed fiber with kidney-shaped section, then washing and drying the PAA as-formed fiber, cyclizing and drafting the same at high temperature stage by stage, and winding and the like, finally obtaining the polyimide (PI) fiber with the kidney-shaped section. The preparation method of the polyimide fiber with the kidney-shaped section has the advantages of simplicity in spinneret hole design and processing, easiness in control of spinning process, high preparation efficiency, low cost for raw materials, low energy consumption and the like and can be used for large-scale industrialized production.

The invention discloses a high-efficiency flame-retardant PP composition special for LFT-D. The composition is prepared from, by weight, 28-68% of polypropylene, 18-21% of halogen-free flame retardant, 10-40% of glass fibers, 2-5% of maleic anhydride grafted polypropylene, 1-4% of maleic anhydride grafted ethylene-octylene copolymer, 0.4-0.7% of lubricant EBS, 0.3-0.7% of main antioxidant and 0.3-0.6% of auxiliary antioxidant. The halogen-free flame retardant is prepared by mixing, by weight, 26-71% of piperazine pyrophosphate, 28-69% of melamine pyrophosphate MPP and 1-5% of zinc salt and then conducting surface treatment with a silane coupling agent or silicone oil. The flame retardant contained in the high-efficiency flame-retardant PP composition special for the LFT-D belongs to phosphorus-nitrogen system expansion-type Halogen-free flame retardants, has efficient flame retardant properties, and causes low corrosion to dies, small amount of smoke during burning and small damage tothe human body and the environment; compared with flame retardants of the same type on the market, on the promise of having the same flame retardant properties, the addition quantity of the halogen-free flame retardants is lower, and the influences on the mechanical properties of the materials are smaller.

A fullerene derivative represented by the formula (I): [wherein, A is a residue of monosaccharides or disaccharides, and Alk is a lower alkylene group, the group represented by the formula (X): is a fullerene residual skeleton, and n is an integral number of 1 or 2]or its salt produces a formulation usable for PDT which has more hydrophilicity and lipophilicity, is expected to have selectivity to tumor cells by cell recognition, shows no toxicity to the cells in a dark place and has a cytocidal effect by light irradiation.

A process for the preparation of a biogasoline component comprising: (I) obtaining at least one bio-oil and, if necessary, liquefying the bio-oil component; (II) adding the bio-oil in liquid form to a FCC unit along with at least one mineral oil; (III) cracking the components added to the FCC unit to form at least a bio-LPG fraction and a bio-naphtha fraction; (IV) alkylating or catalytically polymerising at least part of the bio-LPG fraction; and (V) combining at least a part of the product of step (IV) with at least a part of the bio-naphtha fraction to form a bio-gasoline component.

The invention relates to a method for producing silicon dioxide by using a gas phase process, which radically solves the problem of high cost of the traditional method for producing the silicon dioxide. The method comprises the steps of: enabling a silicon tetrachloride raw material as a by-product obtained during the production of trichlorosilane, hydrogen and air to enter a combustion reactor respectively by adopting an indirect path and a direct path for reacting to generate silicon dioxide primary particles, wherein the total mol ratio of the silicon tetrachloride raw material to the hydrogen to the air is 1:2.05-7:5.1-198; aggregating the silicon dioxide primary particles through an aggregating device into aggregative state particles, carrying out two stages of cyclone separation of two cyclone separators and spraying and deacidifying through a two-stage air injection deacidifying furnace and entering a bin after deacidifying, and packaging by using vacuum compression; and pre-decontaminating the silicon tetrachloride raw material by using a decontaminating gasifier, wherein the decontaminating gasifier comprises three functional sections of a pre-deslagging section, a gasification section and a high boiling point matter separating section. The invention lowers the production cost on the basis of ensuring the high quality of the silicon dioxide.

Disclosed is kind of Vinorelbine solid lipid nanoparticles which comprise (by weight percent) vinorelbine 1-25%, grease material 30-90%, phospholipids 5-50% oleinic acid 0-20%. The preparing process consists of melting liposome material through water-bath, dissolving phosphatides, oleic acid and Vnorelbine with ethanol, dropping into the liposome material, removing ethanol under decompression condition, cooling down and freezing, placing into pH 2-5 aqueous phase, triturating and homogenizing the turbid liquor to obtain the freeze-dried preparation with improved anticancer reactivity of Vinorelbine.

The invention belongs to the technical field of biology and relates to a nucleic acid self-assembled composite nanoflower particle material as well as a preparation method and application thereof. The self-assembled composite material refers to nanoflower particles formed by cocrystallizing contracted nucleic acid and Mg2P2O7, wherein the particle size of the particles is less than 500nm. The self-assembled composite material disclosed by the invention is of a nanoflower structure with high specific surface area, the DNA nanoflower self-assembled composite material has the yield close to 100% and the particle size of 500nm or less, and later utilization is facilitated; moreover, the DNA or RNA in the self-assembled composite material disclosed by the invention is an endogenous macromolecule in animal cells and has low toxicity and excellent biocompatibility, the DNA serves as a carrier of genetic information and can also achieve effects of targeting identification, enzyme catalysis and the like, multifunctional integration of the DNA nanoflower composite material can be realized by introducing functional nucleic acids, natural bio-molecules are totally adopted, and the self-assembled composite material is high in biocompatibility, low in cytotoxicity, low in production cost and favorable or large-scale production and development.

The invention discloses a synthetic Bt insecticidal gene mcry1Ab for transgenosis insect-resistant plants. The Bt insecticidal gene mcry1Ab for transgenosis insect-resistant plants provided by the invention is used for encoding mCry1Ab protein. The mCry1Ab protein is b1), b2) or b3) as follows: b1) the protein with the amino acid sequence as shown in the sequence 2 in a sequence table; b2) the fused protein acquired in the manner of connecting a label with a N end or / and C end of the protein as shown in the sequence 2 in the sequence table; and b3) the protein related to plant insect resistance that is acquired in the manner of substituting and / or deleting and / or adding one or more amino acid residue of the amino acid sequence shown as the sequence 2 in the sequence table. An experiment proves that the mcry1Ab gene can easily acquire the transformant with high expression quantity than the cry1Ab gene, the cry1Ab protein, compared with the mcry1Ab protein, has obvious higher insecticidal activity to ostrinia nubilalis, oriental armyworm, cotton bollworm and dichocrocis punctiferalis, and the mcry1Ab gene has an important popularizing value.