1455 results about "Closed system" patented technology

An artificial intervertebral disc and disc nucleus are described herein having chambers and dampening members. The dampening members may be within or outside of the main body of the device. The chambers may be filled with a suitable liquid, gas, or both, and separated by valves to regulate flow of fluid between chambers, within a dampening member, between the main body and dampening member, or all of the above. Chambers may be filled with responsive hydrogels, EPAM, or other suitable materials, and the device may have activation plates or members, a strain gauge, a pressure sensor, or other means for detecting changes in the materials and / or triggering desired changes in the materials in order to mimic the behavior of a healthy native disc or disc nucleus. A control system may be in communication with the device for receiving feedback and delivering stimuli to initiate desired changes in the fluids or other materials. Membranes may be of variable permeability and may be metallized to ensure as low permeability as possible. Dampening members may be filled during manufacture with carbon dioxide or other suitable gas which may be in a supercritical state and allowed to return to ambient temperature and gaseous state or by other means. Methods of manufacture, delivery of the artificial disc and related structures, and methods of treatment are also described.

The present invention comprises methods and apparatuses that can provide measurement of glucose and other analytes with a variety of sensors without many of the performance-degrading problems of conventional approaches. As apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the removed blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system. A method according to the present invention comprises removing blood from a body, using an analyte sensor to measure an analyte in the removed blood, and infusing at least a portion of the removed blood back into the body. The use of a non-contact sensor with a closed system creates a system will minimal infection risk.

A dispensing device (1) with multi-arm tubing assembly (10) connected to a single source pumping means (12) draws and mixes multiple fluids from plurality of flexible walled sealed supply containers (50a,b) then expels the mixture (60) through nozzle (58) to a target surface (62). Dispensing device (1) provides a closed system whereby no venting occurs, rather supply containers (50a,b) contract in size equal to the volume of fluid expelled. Unstable fluids thus remain protected from exposure to outside air. Additionally, a new use of a repressurization device is disclosed for maintaining the potency of unstable fluids like hydrogen peroxide and a kit is provided which allows user to choose from various components and accessories as needed to suit their multi-chemical dispensing needs.

A closed system, spikeless, positive-flow valve device includes a body defining an internal cavity. At the proximal end of the body is an opening which is preferably sufficiently large to receive an ANSI standard tip of a medical implement. The valve includes a plastic, resilient silicon seal which fills the upper cavity and opening with an oval seal cap having a slit. The opening presses the oval seal cap to keep the slit closed in the decompressed state. The slit opens as the nose of the medical implement compresses the seal into the cavity and the seal cap is free from the opening. The housing also includes a fluid space which facilitates fluid flow between the medical implement and a catheter tip. The fluid space within the valve automatically and reversibly increases upon insertion of the medical implement into the cavity and decreases upon withdrawal of the medical implement, such that a positive flow from the valve toward the catheter tip is effected upon withdrawal of the medical implement, thereby preventing a flow of blood from a patient into the catheter when the medical implement is removed from the valve.

Microscopic batteries, integratable or integrated with microelectromechanical systems or other microscopic circuits, including a MEMS microcircuit, and methods of microfabrication of such microscopic batteries are disclosed, among which comprise closed system microscopic batteries for internal storage of electricity using interval reactants only, which comprise microscopic electrodes, electrolyte and reservoir for the electrolyte.

A method for cultivating algae can include providing a body of water in a substantially enclosed system. The enclosed system can have a length of channel and a cover. The method can optionally include circulating the body of water through the enclosed system under positive pressure conditions. The positive pressure should prevent ingress of any external atmosphere or material. Further, the method can include cultivating the algae in the body of water at conditions which promote growth. Likewise, a system for cultivating algae can include a channel with a cover, water in the channel, and a pump to introduce positive pressure into the system.

Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.

A technique and apparatus to provide status tracking of presence and / or location of a mobile, wireless device to a requesting entity even outside of a particular wireless system. This allows wireless service providers the ability to monitor and log changes in the status of mobile stations within and / or outside their networks. Embodiments are disclosed wherein presence and / or location information is provided to entities outside of a particular servicing wireless network using the mechanisms of call processing components of a mobile network (e.g., call setup procedures), and using standard mechanisms currently available to any appropriately conforming Mobile Switching Center (MSC) element. In one disclosed embodiment, a wireless chat tracking system is implemented which utilizes a change in mobile registration status to automatically notify a chat group system outside the wireless network of current status information activity regarding a relevant device, e.g., registration activity or inactivity timeout. In the wireless chat automatic status tracking system, a registration notification (REGNOT) message is either explicitly forwarded or copied to an external IP based application (e.g., to a mobile chat group system). The change in mobile registration is communicated via a suitable signaling link (e.g., SS7, TCP / IP, etc.) between a Home Location Register (HLR) and the chat group system. Therefore, instead of a conventionally closed system using SS7 messages, REGNOT messages are pushed out over TCP / IP connections to external applications (e.g., chat servers) to automatically notify the external system of the location of a particular user.

The present invention comprises methods and apparatuses that can provide measurement of glucose and other analytes with a variety of sensors without many of the performance-degrading problems of conventional approaches. An apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the removed blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system. A method according to the present invention comprises removing blood from a body, using an analyte sensor to measure an analyte in the removed blood, and infusing at least a portion of the removed blood back into the body. The use of a non-contact sensor with a closed system creates a system will minimal infection risk.

The present invention comprises methods and apparatuses that can provide measurement of glucose and other analytes with a variety of sensors without many of the performance-degrading problems of conventional approaches. An apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the removed blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system. A method according to the present invention comprises removing blood from a body, using an analyte sensor to measure an analyte in the removed blood, and infusing at least a portion of the removed blood back into the body. The use of a non-contact sensor with a closed system creates a system will minimal infection risk.

A closed system, needleless valve device includes a generally tubular body defining an internal cavity. On the proximal end of the body there is an opening which is preferably sufficiently large to receive an ANSI standard tip of a medical implement. The distal end of the body has a generally tubular skirt. The valve also includes a hollow spike having a closed tip. The spike includes at least one longitudinal 18-gauge hole located distal the tip, and is seated inside the cavity such that the tip is below the proximal end of the body. An annular support cuff is connected to the spike which seals off a portion of the cavity of the body such that an upper cavity containing the tip is defined. The valve also includes a plastic, resilient silicone seal which fills the upper cavity and opening and covers the tip of the spike so as to present a flush surface. An adaptor enables the valve to be attached to a resealable container.

A process for cultivating photosynthetic microbes comprising Closed Systems for continuous cultivation and Open Systems for batch cultivation, in which (a) the Closed System Area occupies no more than 20% of the Total Land Area of the cultivation facility; (b) batch cultures in the Open Systems are initiated with an inoculum from the Closed Systems containing a cell biomass of no less than 5% of the carrying capacity of said Open System; (c) the doubling rate of said photosynthetic microbe is no less than once every 16 hours; and (d) the residence time of the batch culture in said Open System is no more than a period of 5 days.

Novel closed system methods and apparatus for the production and utilization of algae are disclosed. A substantially pure form of a desired strain of alga is obtained and cultivated (or isolated and grown). The desired species of alga is isolated from the contaminants and other algae and placed in the controlled environment where its growth is cultivated without contaminants. At desired points in time, a portion of the cultivated alga is removed, with the remainder serving as progenitor stock for growing more of the desired alga. The removed alga is processed and placed in product form.

For measuring the rotational frequency of a movable game device, one resorts to an existing radio signal in the form of a broadcast signal or mobile communication signal within the framework of an open system, or to a radio signal of an evaluation unit within the framework of a closed system, so as to obtain, by means of an antenna having a directivity characteristic, a time-varying radio antenna receive signal which has a low-frequency modulation portion, the frequency of which corresponding to the rotational frequency of the movable game device.

A gas turbine system is configured to inhibit release of carbon dioxide to the atmosphere in such a manner that methane is combusted with oxygen that has been separated from air by an oxygen generator to allow an oxygen combustion type gas turbine to be driven. Carbon dioxide emitted from the turbine is fed under pressure into an underground coal bed along with an air component after separating the oxygen from the air and fixed into the coal bed, and the coal bed methane is collected above the ground by a gas drive action of the gas and supplied to the gas turbine as fuel.

Apparatus for maintaining the temperature of a component of a gas turbine engine below a predetermined maximum working temperature comprises a reservoir for a cooling fluid having a boiling point below the working temperature and in which the component is immersed or with which it is in contact. At least two heat exchangers are associated with the reservoir and operable to effect condensation of vaporized cooling fluid and return of same to the reservoir. Preferably the apparatus is a closed system incorporating three heat exchangers respectively adapted to effect heat exchange with engine fuel, compressed air derived from a fan or low pressure compressor of the engine and ambient air. Means may advantageously be provided to ensure return of condensed cooling fluid to the reservoir when the attitude of the reservoir is altered as a result of aircraft maneuvers.

An electromagnet coil comprising Litz wire windings and power leads without break or interruption is cooled by a perfluorinated liquid by sensible and phase change heat transfer in a closed system. The electromagnet coil may be housed in a pentagonal or hexagonal pressure vessel to allow high packing densities in an array or helmet configuration. The helmet is then lowered over a human cranium for transcranial electromagnetic stimulation. The Litz wire windings reduce the power and voltages required for operation, yet allow production of over 2 T of accurately directed magnetic pulses for direct nerve or neuron stimulation. The perfluorinated liquid maintains the temperature of the helmet to less than 35-40° C., ensuring a comfortable temperature device for a human test subject. A utility cable connects the helmet to an external cooling unit and an external power supply.

This invention relates to in vitro cell culture employing a fibrin network in a flexible gas permeable container. Specifically, the invention is directed to a cell culture container comprising a flexible, gas permeable material with fibrin matrix which is conducive to the culture of anchorage dependent cells, and the container is suitable for use in closed system in vitro cell culture. The gas permeability of the container is sufficient to permit cellular respiration.

Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.

The present invention generally provides methods and devices for removing fluid from a surgical instrument. Surgical access devices and seal systems are generally provided having one or more valves or seal assemblies to create a closed system between the outside environment and the environment in which the surgical access device is being inserted. The devices of systems can also include a fluid remover in the form of a sorbent element, a scraper element, a wicking element, or any combination thereof that is configured to remove fluid from a working channel of the device or system and / or from a surgical instrument inserted therethrough.

Cells present in processed lipoaspirate tissue are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit.

A closed system irrigation connector for use with both 3-way and 2-way urinary catheters is disclosed. The connector fits all urinary catheters and accepts continuous irrigation sets as well as all bulb, piston, and Toomey catheter tip irrigation syringes. The connector eliminates the use of catheter plugs and reduces the mess and leakage often associated with present urinary catheter irrigation procedures. The connector converts an open procedure to a closed system procedure protecting the patient from outside contamination to reduce urinary tract infections as well as the clinician from potentially infectious body fluids. It comprises an assembly of a plastic housing with an internal silicone diaphragm slit valve and a plastic entrance port that are unitized in assembly by sonic welding. The entrance port forms a tapered wedge lock engagement with irrigation sets as well as catheter tip irrigation syringes.

Apparatus and methods are disclosed by which a closed ventilating system accommodates multiple access to the respiratory system of an intubated medical patient without compromising the closed character of the system. Access to the respiratory system through one or more access sites of the closed system apparatus is provided at proximal adapter ports to ventilate the lungs of the patient with gas or gases, to aspirate secretions from the lungs, to oxygenate the lungs to eliminate or reduce residual co2 therefrom, to visually inspect selected parts of the respiratory system, to sample sputum and gases, to sense parameters such as flow rates, pressure, and temperature, to flush with washing solution, and / or to administer medication, gases, and / or lavage. A distal swivel fitting provides multiple sealing sites by which entry of atmosphere is prevented.

Apparatus and methods are disclosed by which a closed ventilating system accommodates multiple access to the respiratory system of an intubated medical patient without compromising the closed character of the system. Access to the respiratory system through one or more access sites of the closed system apparatus is provided at proximal adapter ports to ventilate the lungs of the patient with gas or gases, to aspirate secretions from the lungs, to oxygenate the lungs to eliminate or reduce residual co.sub.2 therefrom, to visually inspect selected parts of the respiratory system, to sample sputum and gases, to sense parameters such as flow rates, pressure, and temperature, to flush with washing solution, and / or to administer medication, gases, and / or lavage. A distal swivel fitting provides multiple sealing sites by which entry of atmosphere is prevented.

A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2.0 to 4.0 mm, a spring loaded syringe holder with a helicoidal spring to apply a substantially constant pressure over the full excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter / duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner. After the bags are centrifuged to concentrate the fat, the excess fluids are separated and the valve is re-connected to permit the syringe pump to reverse fluid flow to graft the concentrated fat back into the patient.

In order to provide a modular arrangement, an inverter for an electric traction motor used to drive an automotive vehicle is positioned in proximity with the traction motor. The inverter is located within a compartment adjacent to one end of the electric traction motor and is cooled in a closed system by spraying a liquid coolant directly onto the inverter. The liquid coolant absorbs heat from the inverter and is cooled by a heat exchange arrangement comprising a reservoir with pipes carrying a second coolant from the radiator of the automotive vehicle. In a preferred embodiment, the coolant is collected from the inverter in an annular reservoir that is integral with the compartment containing the inverter. In accordance with one embodiment of the cooling arrangement, heat from the inverter vaporizes the liquid coolant by absorbing heat from the inverter during a phase change from a liquid to a vapor. The vaporized coolant is condensed by a circulating second coolant in pipes connected to the vehicle's radiator through a condenser that is preferably coaxial with the motor and the annular reservoir, which annular reservoir in the second embodiment collects overspray liquid coolant. In order to avoid degrading the inverter, the coolant is a dielectric fluid.

In a class of embodiments, the invention is an open computing system (e.g., a PC) in which a protected, closed subsystem is embedded. The closed subsystem typically includes multiple parts that ensure that content protection keys and protected content are never revealed outside the closed subsystem. Content (e.g., high-definition digital video) that enters the closed subsystem (and is typically decrypted and re-encrypted within the closed subsystem) is afforded a similar level of protection within the open system as can be obtained in standalone closed systems. Other aspects of the invention are methods for protecting content within an open computing system, a closed system (or disk drive thereof) configured to be embedded in an open computing system, and circuitry configured to be embedded in an open computing system for combining the output of a closed subsystem with other output (e.g., graphics and / or audio output) of the open computing system.