41 results about "Pyruvaldehyde" patented technology

Compositions for generating a cooked flavor in a foodstuff, comprising specified flavor precursors that react on heating to generate the flavor and maintain a reactive association after inclusion in the foodstuff. The compositions may include combination of a sulphur source, e.g. hydrogen sulphide, methane thiol, a sulfur-containing amino acid, thiamine, cystine, sodium sulphide, ammonium sulphide, ammonium polysulphide, onions, garlic, shallots, eggs, methionine, and mixtures thereof, and at least one reductone, e.g. a furanone, a ketone, a pyrone, an aldehyde, a carbonyl compound, isomaltol, maltol, pyruvaldehyde, hydroxyacetone, 3-deoxyglucosone, 5-hydroxy-5,6-dihydromaltol, 2,3-butanedione, 3-hydroxy-2-butanone, a process flavor, cooked vegetable concentrates, soy sauce, and mixtures thereof.

The invention provides a preparation method of 3-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-2-formyl-1, 4-dihydropyridine-5-isopropyl carbonate. The method comprises the following steps that condensation and amination reactions between pyruvic aldehyde dimethyl acetal and dimethyl carbonate are carried out under the catalysis of a strong base to obtain 3-amino-4, 4-dimethoxyl-methyl crotonate; dehydration condensation reaction between isopropyl acetoacetate and nitrobenzaldehyde is carried out under the catalysis of a weak base to obtain 2-(3-nitrobenzylidene)-isopropyl acetoacetate; dehydration condensation and hydrolysis reactions between 3-amino-4, 4-dimethoxyl-methyl crotonate and 2-(3-nitrobenzylidene)-isopropyl acetoacetate are carried out to obtain 3-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-2-formyl-1, 4-dihydropyridine-5-isopropyl carbonate. The method provided by the invention solves the technical problems in the prior art including complex preparation process, low purity and less yield during the preparation of nilvadipine intermediate 3-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-2-formyl-1, 4-dihydropyridine-5-isopropyl carbonate.

The present invention relates to a folic acid synthesis method. According to the present invention, with the method, a 2,4,5-triamino-6-hydroxypyrimidine salt, 3-halogenated pyruvaldehyde oxime and N-(4-aminobenzamide)-L-glutamic acid are subjected to a reaction to prepare the folic acid; and the 3-halogenated pyruvaldehyde oxime is used to replace the low purity 1,1,3-trichloroacetone, such that the generation of a large amount of waste water in the traditional method is avoided, the reaction conditions are mild, the operation is easy, the reaction selectivity is good, the product purity is high, the advantages of safety and environmental protection are provided, and the method is suitable for the industrial requirements on environmental protection.

The invention provides a biological reducing preparation method of a catalyst used for synthesizing pyruvaldehyde, which relates to a catalyst used for synthesizing pyruvaldehyde. The invention provides the biological reducing preparation method of the catalyst used for synthesizing the pyruvaldehyde. The biological reducing preparation method comprises the following steps of: preparing microorganisms with expanded culture into bacterium powder for later use by drying and grinding; preparing the bacterium powder into bacterium suspension, then mixing with an alkali solution and a silver compound and obtaining mixed liquid containing biomass and nano silver sol after reacting; separating the mixed liquid centrifugally and collecting supernatant liquid to obtain silver sol wrapt with the biomass; after drying a lower-layer precipitate, obtaining lower-layer silver powder; evaporating and concentrating the silver sol, adding an organic solvent to dewater and precipitate silver colloidal particles, filtering or centrifugally separating and collecting a precipitate; after drying, obtaining upper-layer silver powder; and dissolving the upper-layer silver powder or the lower-layer silver powder into deionized water, adding a carrier according to the mass ratio of 1:(0.1 to 0.4) of the carrier to the silver powder and obtaining a product after soaking, drying and calcining.

The invention discloses a method for detecting AGEs (Advanced Glycation End Products) and application. The method comprises the following steps: firstly preparing a glassy carbon electrode modified bygraphene-chitosan/N(epsilon)carboxymethyl lysine, and then realizing multi-residue detection on five AGEs comprising the N(epsilon)carboxymethyl lysine, N(epsilon)carboxyethyl lysine, pentosidine, pyruvaldehyde imidazolinone and argpyrimidine by combining an indirect competition method on the basis of a principle that cross immunoreaction can be generated by a pentosidine monoclonal antibody andmultiple AGEs. According to the method for detecting the AGEs, disclosed by the invention, the problem that a current AGEs detecting method just can be used for detecting a single substance is solved,higher sensitivity (of which the detecting limit is 0.06 to 0.1 ng/mL) and wider linear range (0.1 to 1000 ng/mL) are obtained, the operation is simple, the cost is lower, the demands on clinical AGEs detection of a human body can be completely fitted, and important practical application value is obtained.

The invention relates to a preparation method of a polysubstituted bromomethyl benzo nitrogenous heterocyclic compound. The preparation method is carried out by using an ultrasonic extraction device,and is characterized by comprising the following steps: reacting pyruvic aldehyde dimethyl acetal with o-bromobenzylamine in toluene to obtain N-(2-bromophenyl)-1,1-dimethoxypropan-2-imine; and carrying out five steps to obtain 3-methyl-8-bromomethyl isoquinoline hydrobromide which is a final product. Extraction is implemented by an ultrasonic extraction device, and a preparation step, a coveringstep, a vibration shaking step, a repeating step and a receiving step are included. The ultrasonic extraction device comprises an extraction part (1), a shell part (2), an ultrasonic part (3), a transverse rod part (4), a left supporting part (5), a right supporting part (6), a glass device (7) and a demulsification assembly (8).

The invention discloses a 4-(diethoxy-phosphoryl)-2-methyl-but-2-enoate preparation method, which comprises: (a) carrying out an oxidation reaction on a pyruvic aldehyde aqueous solution to obtain a pyruvic acid/pyruvate aqueous solution; and (b) carrying out a reaction on the pyruvic acid/pyruvate aqueous solution and tetraethyl ethylene diphosphate, and performing an esterification reaction withan alcohol to obtain 4-(diethoxy-phosphoryl)-2-methyl-but-2-enoate. The method of the invention has advantages of cheap and easily available raw materials, simple operation of each step, high yield of the whole route, and high industrial application value.

The invention belongs to the field of organic synthesis, and particularly relates to a synthesis method of 13-methyl berberine alkaloid. The method comprises the following steps: reaction a: taking arylethylamine and aryl formaldehyde as main starting raw materials, and reacting in the presence of other auxiliary materials to obtain secondary amine hydrochloride; and reaction b: taking secondary amine hydrochloride and pyruvic aldehyde as main raw materials, and reacting in the presence of other auxiliary materials to obtain the 13-methyl berberine alkaloid. According to the invention, aryl ethylamine and aryl formaldehyde are used as raw materials to synthesize secondary amine hydrochloride, and then the secondary amine hydrochloride and pyruvic aldehyde are subjected to Pickering-Schengger reaction/Friedel-Crafts hydroxyalkylation reaction/dehydration reaction/oxidation reaction in an anhydrous formic acid solution under the assistance of a dewatering agent and an oxidizing agent, so that the 13-methylberberine alkaloid is prepared at the yield of more than 80%, and the synthesis steps are simplified and easy to operate; and various expensive metal catalysts and excessive acid catalysis are not needed, the productivity is high, and the cost is low.

The invention relates to a method for preparing lactic acid by catalyzing pyruvic aldehyde. The method comprises the following steps: contacting pyruvic aldehyde, water and a catalyst in a reactor, and reacting to obtain a product containing lactic acid, wherein the molar ratio of the pyruvic aldehyde to the water is 1:(40-350), the reaction temperature is 30-180 DEG C, the reaction time is 1-10 hours, the catalyst contains a tin-titanium-silicon molecular sieve, and the weight ratio of the pyruvic aldehyde to the tin-titanium-silicon molecular sieve based on dry basis weight is 1:(1-6). The method provided by the invention has high pyruvic aldehyde conversion rate and high lactic acid yield.

The invention relates to a preparation method of polysubstituted benzo nitrogen-containing heterocyclic methylamine, which is carried out by using an ultrasonic extraction device and is characterizedby comprising the steps of preparing N-(2-bromophenyl)-1, 1-dimethoxypropane-2-imine from pyruvic aldehyde dimethyl acetal and o-bromobenzylamine; and preparing a red viscous oily matter 3-methylisoquinoline-8-methylamine through four steps to obtain a final product. The extraction is implemented by an ultrasonic extraction device, and comprises a preparation step, a covering step, a vibration shaking step, a repeating step and a receiving step. The ultrasonic extraction device comprises an extraction part (1), a shell part (2), an ultrasonic part (3), a transverse rod part (4), a left supporting part (5), a right supporting part (6), a glass device (7) and a demulsification assembly (8).

The invention discloses a rutin-pyruvaldehydeadduct, a preparation method and application, and belongs to the technical field of standard substance synthesis and food detection. The molecular formula of the rutin-pyruvaldehyde adduct is C33H36O20 or C33H34O20. The preparation method comprises the steps of adding rutin and pyruvaldehyde into a phosphoric acid buffer salt solution according to the molar ratio of (10: 1) to (1: 10); under stirring, performing constant-temperature heating reaction to obtain a mixed solution containing the rutin-pyruvaldehyde adduct, separating and purifying the mixed solution to obtain the high-purity rutin-pyruvaldehyde adduct. The adduct is used for detecting the pyruvaldehyde adduct in food and can be used for rapidly and quantitatively detecting the content of the rutin-pyruvaldehyde adduct in the food. The exposure level of the rutin-pyruvaldehyde adduct in the food is evaluated, so that the safety of the food is comprehensively evaluated.