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386 results about "Downstream processing" patented technology

Downstream processing refers to the recovery and the purification of biosynthetic products, particularly pharmaceuticals, from natural sources such as animal or plant tissue or fermentation broth, including the recycling of salvageable components and the proper treatment and disposal of waste. It is an essential step in the manufacture of pharmaceuticals such as antibiotics, hormones (e.g. insulin and humans growth hormone), antibodies (e.g. infliximab and abciximab) and vaccines; antibodies and enzymes used in diagnostics; industrial enzymes; and natural fragrance and flavor compounds. Downstream processing is usually considered a specialized field in biochemical engineering, itself a specialization within chemical engineering, though many of the key technologies were developed by chemists and biologists for laboratory-scale separation of biological products.

Dynamic stabilization for a stream processing system

Disclosed are a method, upstream processing node, and computer readable medium for dynamically stabilizing a stream processing system. The method includes receiving at least one computing resource allocation target. The further includes determining that an input data flow rate of at least one upstream processing element varies. The computing resource is dynamically allocated to the upstream processing element in response to the input rate of the upstream processing element varying. Data flow is dynamically controlled between the upstream processing element and at least one downstream processing element.
Owner:IBM CORP

Valve

InactiveUS7350535B2Undesired movement is also preventedCompromising sterilityCheck valvesEqualizing valvesDownstream processingActuator
A valve apparatus (100) for use in sterile fluid transfer or isolator systems has open entry (10) and exit (11) sides and a passageway (9) for fluid between the entry (10) and the exit (11) sides. The entry side (10) is connectable to an opening (4c) of a vessel or pipe (4) and the exit side (11) is connectable to downstream processing by means such as tubing, a vessel or a pipe. The entry side (10) includes a rupturable seal (2a) blocking the open entry side (10). Valve (100) also includes an actuator (5) attached to a piston (1) which moves within the valve (100), the piston being connected to the seal so that on movement of the piston, the seal is torn free from the entry side thereby allowing fluid gain entry to the valve (100) and to pass along the passageway (9) between the open entry (10) and exit (11) sides to downstream processing.
Owner:G A APOLLO

System and/or method for heat treating conductive coatings using wavelength-tuned infrared radiation

Certain example embodiments relate to systems and / or methods for preferentially and selectively heat treating conductive coatings such as ITO using specifically tuned near infrared-short wave infrared (NIR-SWIR) radiation. In certain example embodiments, the coating is preferentially heated, thereby improving its properties while at the underlying substrate is kept at low temperatures. Such techniques are advantageous for applications on glass and / or other substrates, e.g., where elevated substrate temperatures can lead to stress changes that adversely effect downstream processing (such as, for example, cutting, grinding, etc.) and may sometimes even result in substrate breakage or deformation. Selective heating of the coating may in certain example embodiments be obtained by using IR emitters with peak outputs over spectral wavelengths where the conductive coating (or the conductive layer(s) in the conductive coating) is significantly absorbing but where the substrate has reduced or minimal absorption.
Owner:GUARDIAN GLASS LLC

Article-orienting conveyor

A conveyor for orienting and registering articles in a preferred orientation and position for accurate downstream processing. The conveyor includes a conveyor belt running in a conveyance direction next to an orientation belt running parallel in an opposite direction or more slowly in the same direction. The orientation belt has upstanding structure, such as flights, or a high-friction surface. The conveyor belt includes article-supporting rollers on a top side. The rollers are arranged to rotate about axes oblique to the conveyance direction. The rollers also extend below the bottom side of the belt and are rotated by dynamic contact with bearing surfaces supporting the belt as it advances in the conveying direction. The rotating rollers direct conveyed articles toward a side rail. If a portion of a conveyed article extends past the side edge of the conveyor belt into the path of the orientation belt, the obstructions or high-friction surface of the slower- or oppositely-moving orientation belt strikes the conveyed articles and cause them to rotate clockwise toward an alignment of the article in the conveyance direction and into registration against the side rail at the downstream end of the conveyor. In other versions of the article-orienting conveyor, the orientation belt is replaced by a row of posts or a rotating paddle wheel that strikes conveyed articles extending past the side edge of the conveyor belt.
Owner:LAITRAM LLC

Article-orienting conveyor

A conveyor for orienting and registering articles in a preferred orientation and position for accurate downstream processing. The conveyor includes a conveyor belt running in a conveyance direction next to an orientation belt running parallel in an opposite direction or more slowly in the same direction. The orientation belt has upstanding structure, such as flights, or a high-friction surface. The conveyor belt includes article-supporting rollers on a top side. The rollers are arranged to rotate about axes oblique to the conveyance direction. The rollers also extend below the bottom side of the belt and are rotated by dynamic contact with bearing surfaces supporting the belt as it advances in the conveying direction. The rotating rollers direct conveyed articles toward a side rail. If a portion of a conveyed article extends past the side edge of the conveyor belt into the path of the orientation belt, the obstructions or high-friction surface of the slower- or oppositely-moving orientation belt strikes the conveyed articles and cause them to rotate clockwise toward an alignment of the article in the conveyance direction and into registration against the side rail at the downstream end of the conveyor. In other versions of the article-orienting conveyor, the orientation belt is replaced by a row of posts or a rotating paddle wheel that strikes conveyed articles extending past the side edge of the conveyor belt.
Owner:LAITRAM LLC

Biomass energy prepared by one-step method of microalgae

The invention provides a method for preparing biodiesel from microalgae. The method comprises the following steps of: a. changing collected microalgae from the wet algae into algae block or algae powder; b. mixing a catalyst into low-carbon alcohol, directly adding the algae block or the algae powder obtained by the step a, and carrying out ester exchange reaction to prepare the biodiesel; c. after the reaction is stopped, adding an organic solvent for extracting reaction solution which is divided into organic solvent phase used for extraction, low-carbon alcohol water-adding phase and algae mud; and d. after the extraction is completed, collecting the organic solvent phase used for extraction, removing the organic solvent by distillation, and obtaining oily liquid, namely crude products of the biodiesel. After preparing the biodiesel, the steps that the low-carbon alcohol water-adding phase is used circularly after dewatered by a solid drying agent, and the produced algae mud is used for producing biogas by biological fermentation are added. The invention completes the oil extraction of microalgae and biodiesel production by one step, simplifies the technique steps and equipment, saves cost; the sulphuric acid and low-carbon alcohol used for production can be recovered, then dewatered by drying, then utilized repeatedly, the cost is reduced, the final product is neutral, does not need washing and reduces the downstream processing pressure; and simultaneously, chlorophyll is mainly concentrated in the low-carbon alcohol, reduces the interference of the chlorophyll to the color of the product and does not need the step of decoloring.
Owner:ENN SCI & TECH DEV

Sedimentation removal assembly for flow-through sedimentary tank

Solids removal assemblies (14) adapted for use in flow-through or batch-type sedimentation tanks (12) are provided which increase the efficiency of solids removal and eliminate physical scraping devices common with such sedimentation tanks. The preferred removal assemblies (14) include an elongated hood (34) disposed over a cooperating and complementally configured fill structure (26,28), which fills the majority of the internal volume of the hood (34). The hood (34) includes converging sidewalls (44, 46) having lower most inlet openings (54) and spaced, tubular outlets (56) adjacent the apex thereof. Outlet pipes (64) are operably coupled with each of the hood outlets (56) for suction withdrawal of waste water-solids suspensions which are then conveyed for downstream processing. The hood (34) and fill structure (26, 28) cooperatively define restricted flow paths for the waste water-solids suspensions, and assist in the creation of relatively high velocity movement of the suspensions to prevent bridging or clogging by collective solids adjacent the bottom of the tanks (12).
Owner:AERO MOD

Surface topography with X-ray reflection phase-contrast microscopy

A system and method for monitoring a surface or interfacial area. The system and method includes an intense X-ray beam directed to a surface or interface at a low angle to achieve specular reflection with phase contrast associated with an event, such as changing topography, chemistry or magnetic state being detected by a CCD. Upstream or downstream processing can be carried out with the X-ray phase contrast system.
Owner:UCHICAGO ARGONNE LLC

Orienting and feeding apparatus and method for manufacturing line

Apparatus and methods for rapidly orienting and feeding generally cylindrical, elongated objects having a maximum transverse diameter Y. First and second conveying belts are provided having input and output ends for cooperatively conveying such objects toward a downstream processing line. The belts are mounted so that their respective conveying surfaces are movable in a common parallel direction. The facing edges of the conveying surfaces of these belts are spaced from one another to define a uniform gap between them of a dimension less than Y. The conveying surfaces are upwardly sloped away from the gap, to define a zone converging downwardly in the direction of the gap. Object input means deposit the initially unoriented elongated objects at the input ends of the conveying belts. The belts are moved in a common direction, but at different speeds. The elongated objects are rotated by contact with the differentially speeding belts as they descend into the converging zone and become supported at the gap and conveyed by riding on the edges of the moving belts which border the gap. The objects as they descend become oriented in positions of gravitationally maximum stability relative to the mode of support, these positions being characteristic for the objects. Object output means at the ends of the belts receive the oriented objects and direct them toward the downstream processing line.
Owner:NORWALT DESIGN
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