The invention discloses a catadioptric hybrid multispectral imaging system, which comprises a primary mirror, a catadioptric dual-purpose secondary mirror, a wedge-shaped dichroic beam splitter, a medium wave or long wave infrared or medium-long wave infrared dual-waveband imaging mirror assembly, a medium wave or long wave infrared or medium-long wave infrared dichroic detector unit, a visible to near infrared waveband imaging mirror assembly, a visible to near infrared waveband beam splitting device and a detection unit thereof, a short wave infrared waveband imaging mirror assembly, and a short wave infrared waveband beam splitting device and a detection unit thereof, wherein a hole is formed at the center of the primary mirror, and the reflecting surface of the primary mirror is a concave surface; and the incident surface of the catadioptric dual-purpose secondary mirror is a convex surface. The system can realize imaging with common field of view and common aperture of a same object, improve the utilization rate of light energy, save space for the beam splitter and the system, prevent parasitic light from directly leaking into the imaging mirror assembly from the hole formed on the primary mirror, correct asymmetric aberration, be more conductive to realizing large aperture and the larger field of view and significantly improve the imaging quality. The imaging with the same optical axis and the common field of view can enable an image to be easy to register.