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57 results about "Neomycin sulphate" patented technology

Neomycin sulfate is an antibiotic drug that effectively kills or inhibits bacteria in humans and animals. Applied orally, neomycin sulfate is used to treat infections of the intestine and as a preliminary treatment before gastrointestinal surgery.

Medicinal cream made using neomycin sulphate, betamethasone valerate, and chitosan, and a process to make the same

The present invention is directed to a composition for treating bacterial skin infections & skin inflammation, along with skin rejuvenation. More particularly, the present invention relates to a pharmaceutical cream comprising a biopolymer, a corticosteroid and an antibacterial active ingredient. It discloses a composition for treating bacterial skin infections & skin inflammation, along with skin rejuvenation containing a) a biopolymer in the form of chitosan, b) a combination of active pharmaceutical ingredients (APIs), neomycin sulphate & betamethasone valerate used in treating bacterial skin infections & skin inflammations, c) a cream base containing primary and secondary emulsifiers, waxy materials, co-solvents, acids, preservatives, buffering agents, anti oxidants, chelating agents, and humectants and d) water. The active ingredients, namely chitosan, a corticosteroid Betamethasone Valerate, and an antibacterial agent Neomycin Sulphate, are incorporated in cream base for use in treating bacterial skin infections and skin inflammation due to allergy & itching, & wounds on human skin involving contacting human skin with the above identified composition.
Owner:SULUR VANANGAMUDI SUBRAMANIAM +4

Antimycotic externally used drug

The invention discloses an externally-used medicament for treating skin mycosis diseases, which is prepared from the raw materials of (by weight percent) terbinafine hydrochloride or miconazole or ketoconazole 0. 5-2%, Clobetasol Propionate 0. 01-0. 2%, neomycin sulphate 0. 3-1%, bee glue 5-25%, and balancing distilled water.
Owner:程贵昌

Compound neomycin sulphate solution and preparation method thereof

The invention discloses a compound neomycin sulphate solution and a preparation method thereof. The invention aims to provide a compound neomycin sulphate solution which has obvious effect on treating gastrointestinal infection of birds, treats symptoms and a root and reduces the medicine application frequency and a preparation method thereof. 100 L of solution comprises 2-15 kg of neomycin sulphate, 3-15 kg of colistin sulphate, 0.01-0.05 kg of scopolamine methobromide, 10 kg of alcohol with concentration of 95 percent and the balance of purified water. The invention adopts the neomycin sulphate and the colistin sulphate as antibacterial components, has double effects, can effectively reduce the medicine resistant rate of bacteria and has effect on common Gram negative bacteria causing intestinal infection; and the scopolamine methobromide inhibits glandular secretion, dries intestinal contents and lightens a dehydration symptom so as to have a rapid therapeutic effect.
Owner:TIANJIN SHENGJI GRP CO LTD

Medical composition for treating piglet diarrhea

InactiveCN102406659APrevention and control of morbidityPrevention and control of refeedingAntibacterial agentsDigestive systemBiotechnologySodium bicarbonate
The invention discloses a medical composition for treating piglet diarrhea, comprising the following raw materials in parts: 50-100 parts of neomycin sulfate, 10-50 parts of scopolamine methobromide, 100-150 parts of montmorillonite, 1-5 parts of VB1, 1-5 parts of VB2, 1-5 parts of VB6, 10-50 parts of nicotinamide, 10-50 parts of calcium pantothenate, 1-10 parts of sodium chloride, 1-12 parts of sodium bicarbonate, 1-10 parts of potassium chloride and 100-150 parts of anhydrous dextrose. The medical composition disclosed by the invention is used for treating piglet diarrhea and dehydration caused by diarrhea, so that morbidity and mortality of the piglet diarrhea are effectively prevented and controlled.
Owner:GUANGDONG ZIJIN ZHENGTIAN PHARMA

Clean production method for neomycin sulfate fermentation

A clean production method for neomycin sulfate fermentation includes the following steps: step 1, preparing slant spore suspension liquid; step 2, preparing seed liquid; step 3, supplementing a supplementary culture medium and ammonium sulfate in a fermenting process to enable the accumulation amount of neomycin to reach a fermentation endpoint, and stopping fermentation to obtain fermenting liquid, wherein a fermentation basal culture medium comprises 2-10% (W / V) of maltodextrin and does not contain rice flour, starch and alpha-amylase, and the supplementary culture medium comprises 20-45% (W / V) of the maltodextrin and does not contain the rice flour, the starch and the alpha-amylase; step 4, pouring the fermenting liquid into an adsorption tank, and adding resin to adsorb the neomycin toobtain the finished neomycin sulfate. The clean production method for neomycin sulfate fermentation has the advantages that the problems of large pollution and high energy consumption can be solved,the utilization rate of high-carbon-source substances can be increased, and clean production can be realized.
Owner:YICHANG SANXIA PHARMA

Neomycin sulfate production wastewater treatment method

The invention discloses a neomycin sulfate production wastewater treatment method. The method comprises the following steps: (1) regulating water quality and water quantity; (2) carrying out solid-liquid separation on the wastewater; (3) performing an electrochemical reaction; (4) removing sulfate; (5) performing desulfurization; (6) removing COD and BOD substances; (7) comprehensively adjusting water quality and water quantity; (8) performing ozone oxidation; (9) performing an AAO process; (10) carrying out secondary precipitation; (11) performing sludge treatment; and (12) flocculating and precipitating. According to the method, the biodegradability of the neomycin sulfate production wastewater is improved, high sulfate radicals, most ammonia nitrogen and TP in the water are removed, onthe basis of fully exerting the advantages of anaerobic treatment, the occupied area and the operating cost of investment are saved, the treatment difficulty of the subsequent aerobic biochemical process stage is reduced, and good social and economic benefits are achieved.
Owner:河南双辰环保工程有限公司

Medicinal Cream Made Using Neomycin Sulphate, Betamethasone Valerate, And Chitosan, And A Process To Make The Same

The present invention is directed to a composition for treating bacterial skin infections & skin inflammation, along with skin rejuvenation. More particularly, the present invention relates to a pharmaceutical cream comprising a biopolymer, a corticosteroid and an antibacterial active ingredient. It discloses a composition for treating bacterial skin infections & skin inflammation, along with skin rejuvenation containing a) a biopolymer in the form of chitosan, b) a combination of active pharmaceutical ingredients (APIs), neomycin sulphate & betamethasone valerate used in treating bacterial skin infections & skin inflammations, c) a cream base containing primary and secondary emulsifiers, waxy materials, co-solvents, acids, preservatives, buffering agents, anti oxidants, chelating agents, and humectants and d) water. The active ingredients, namely chitosan, a corticosteroid Betamethasone Valerate, and an antibacterial agent Neomycin Sulphate, are incorporated in cream base for use in treating bacterial skin infections and skin inflammation due to allergy & itching, & wounds on human skin involving contacting human skin with the above identified composition.
Owner:SULUR VANANGAMUDI SUBRAMANIAM +4

Neomycin sulfate solution and preparation method thereof

The invention discloses a neomycin sulfate solution comprising the following ingredients by weight percent: 5-30% of neomycin sulfate, 0.5-1% of vitamin C, 0.5-1% of sorbitol, 0.1-1% of vanillin and the balance of water. The invention also discloses a preparation method of the neomycin sulfate solution. The neomycin sulfate solution disclosed by the invention is simple in preparation, convenient to use, and long in storage time.
Owner:QINGDAO BOITE BIOPHARM

Thermo-sensitive type gel eye drops, as well as preparation method and application thereof

The invention discloses thermo-sensitive type gel eye drops, as well as a preparation method and application thereof. The eye drops comprise prescription active ingredients, gel matrix, a preservative, a metal ion chelating agent, an isoosmotic adjusting agent and water for injection, wherein the prescription active ingredients comprise neomycin sulfate and dexamethasone sodium phosphate; the gel matrix comprises poloxamer 407 and poloxamer 188; the preservative comprises benzalkonium bromide; the metal ion chelating agent is ethylene diamine tetraacetic acid; and the isoosmotic adjusting agent is sodium chloride. Preferably, the eye drops also comprise a moisturizing agent and a bioadhesive material. The eye drops, disclosed by the invention, have the following advantages: (1) administration is facilitated, the medicine liquid has adhesion, retention and sustained release effects on the surface of retina, the administration frequency can be reduced, the medicine loss can be reduced and the compliance of a patient can be improved; (2) the eye drops are simple in preparation process, low in cost and suitable for large-scale production; and (3) the eye drops have good antibacterial and anti-inflammatory effects, low irritability and high safety.
Owner:SOUTHWEST UNIVERSITY

Soluble powder for treating digestive system infection of livestock and poultry

The invention relates to soluble powder for treating digestive system infections of poultry, comprising neomycin sulphate, berberine hydrochloride and auxiliary materials. As an antibiotic medicine, the inventive medicament is mainly used to prevent and treat diarrhea and diarrhea caused by a plurality of bacterial infections, such as colibacillosis in chickens, pullorosis, salmonellosis, avian typhus, paratyphoid, white scour of piglets, bacillary dysentery and diarrhea of grown pigs etc. The berberine hydrochloride and the neomycin sulphate have compatibility when used together. The soluble powder acts on diarrhea and diarrhea caused by a plurality of bacterial infections, has good absorption and relatively high safety when orally taken, and is suitable for being popularized in animal husbandry.
Owner:TIANJIN RINGPU BIO TECH

Medicinal composition for treating hemorrhoids

The invention relates to a medicinal composition for treating hemorrhoids. The medicinal composition is formed by mixing active ingredients consisting of hydrocortisone, neomycin sulphate, dibucaine and aesculin and pharmaceutically acceptable auxiliary materials. The optimal using amount for the components is that every unit of the composition comprises 5.0mg of hydrocortisone, 7.1mg of neomycin sulphate, 5.0mg of dibucaine and 10.0mg of aesculin. The composition can be prepared into external preparations such as suppository and ointment and can be used for treating various types of hemorrhoids.
Owner:北京利乐生制药科技有限公司

Compound florfenicol preparation for aquatic products and preparation method and application thereof

The invention discloses a compound florfenicol preparation for aquatic products and a preparation method and application thereof. The compound florfenicol preparation for the aquatic products consists of the following components in percentage by mass: 5 to 20 percent of florfenicol, 1 to 25 percent of neomycin sulfate and the balance of glucose. The florfenicol and the neomycin sulfate are combined, so that the antibacterial effect of the compound florfenicol preparation for the aquatic products can be improved, the prevention and treatment effects of the compound florfenicol preparation on the bacterial diseases of the aquatic products are effectively improved, and medicine consumption and cost are reduced; and the preparation method of the compound florfenicol preparation for the aquatic products is simple and practicable and greatly improves bioavailability, and the preparation has high solubility.
Owner:清远海贝生物技术有限公司

Composition for preventing pig diarrhea and preparation technology thereof

The invention provides a composition for preventing pig diarrhea. The composition is composed of the following components in parts by weight: 5 parts of neomycin sulfate, 25 to 45 parts of ethyl lactate, 30 to 50 parts of cherokee rose fruit, 20 to 30 parts of radix codonopsis, 20 to 30 parts of bighead atractylodes rhizome, 25 to 35 parts of radix scutellariae, 25 to 35 parts of coptis, 15 to 25 parts of Chinese yam, 20 to 30 parts of dried orange peel, 25 to 35 parts of kudzu vine root, 10 to 20 parts of oriental waterplantain rhizome, 10 to 20 parts of nutmeg, 12 to 24 parts of raspberry, 10 to 30 parts of isatis root, 5 to 15 parts of haw, and 5 to 15 parts of licorice. Compared to the prior art, the prepared composition for preventing pig diarrhea has the advantages of low cost, simple technology, no side or toxic effect, safety, and reliability, and is capable of preventing the happening of pig diarrhea.
Owner:JURONG MANYUANCHUN FAMILY FARM

Method for extracting framycetin sulphate from neomycin sulphate

The invention provides a method for extracting framycetin sulphate from neomycin sulphate. The method comprises the following steps of S1, dissolving concentrated neomycin sulphate raw powder with purified water to obtain a neomycin sulphate concentrated solution, and adding chromatographic resin for adsorption; S2, washing the saturated chromatographic resin in the step S1 with ammonia water; S3,eluting the treated chromatographic resin in the step S2 with ammonia water to obtain an eluate; S4, concentrating the eluate with a thin-film evaporator to obtain a concentrated solution; S5, carrying out salt conversion operation on sulfuric acid in the concentrated solution; S6, adding activated carbon into the concentrated solution subjected to salt conversion, and performing decolorization and pressing filtration to obtain a decolorized solution; and S7, spray-drying the decolorized solution at 135 DEG C to obtain the finished framycetin sulphate. According to the method, spray drying isadopted to replace crystallization operation, and no organic solvent is used, so that no organic solvent residues exist in the formed finished framycetin sulphate, the yield and the product quality of the finished framycetin sulphate are improved, the production cost is low, and no organic matter is generated after waste liquid is discharged.
Owner:吕志洪

Premix for treating infection of livestock and poultry caused by sensitive bacteria

The invention relates to a premix for the treatment of sensitive bacteria infection of fowl and livestock containing neomycinsulphat, berberine hydrochloride and accessories. The inventive medicament is used as antibiotics for the treatment of partial or systemic infection caused by the sensitive bacteria. The formula of the invention combines neomycinsulphat and berberine to enhance the effect of oral administration and comparatively high safety. The invention is fit for being applied to animal husbandry production.
Owner:TIANJIN RINGPU BIO TECH

Method for detecting neomycin sulfate components and related substances

The invention provides a method for detecting neomycin sulfate components and related substances. According to the invention, an HPLC-ELSD method is adopted for detection, and chromatographic conditions are as follows: a chromatographic column is ACE C18-PFP, 4.6 * 250 mm, 3 [mu] m; a mobile phase A is 0.1-5.0 wt% of trifluoroacetic acid aqueous solution, and a mobile phase B is methanol; the temperature of a drift tube is 30-100 DEG C, and the carrier gas pressure is 20-60 Psi. According to the detection method provided by the invention, neomycin sulfate components B and C, known impurities and a plurality of unknown impurities are effectively separated; through research and verification of specificity, sensitivity and other methodologies, it is found that the method is sensitive, accurate and high in reproducibility, more impurities in neomycin sulfate can be qualitatively and quantitatively detected through a simpler and more convenient method, and reliable guarantee is provided forimproving and better controlling the quality of neomycin sulfate products.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY +1

Reagent erythrocyte preservation system and preparation method thereof

ActiveCN111713487AExtended shelf lifeHigh ratio of morphologyDead animal preservationAntigenInosine
The invention relates to a reagent erythrocyte preservation system and a preparation method thereof. The reagent erythrocyte preservation system comprises the following components: 0.400 g / L of citricacid-1 water, 6.100 g / L of trisodium citrate dihydrate, 20.500 g / L of glucose, 0.350 g / L of inosine, 0.143 g / L of chloramphenicol, 0.143 g / L of neomycin sulfate, 4.200g / L of NaCl, 0.500 g / L of adenine, 4.000 g / L of mannitol, and 3.000 g / L of potassium dihydrogen phosphate. Experiments prove that when the reagent erythrocyte preservation system is used for storing 3% of reagent erythrocytes at 2-8DEG C, the reagent erythrocytes can be effectively preserved for 90 days, and 15% of the reagent erythrocytes can be effectively preserved for 60 days. The preservation system has the advantages thatthe reagent erythrocytes obtained by using the preservation system are long in effective period, normal in appearance, high in red blood cell form proportion and good in antigen stability.
Owner:SHANGHAI BLOOD CENT

Antibacterial and antiviral degradable non-woven fabric as well as preparation method and application thereof

The invention relates to an antibacterial and antiviral degradable non-woven fabric as well as a preparation method and application thereof. The non-woven fabric is a cellulose spunlace non-woven fabric, and the non-woven fabric contains an organic antibacterial agent and / or antibiotic. The organic antibacterial agent is a modified guanidyl polymer, and the antibiotic is neomycin sulfate. A mask sequentially comprises the antibacterial and antiviral degradable non-woven fabric, a second fabric layer and a third fabric layer from outside to inside. According to the antibacterial and antiviral degradable non-woven fabric, the mask can be endowed with long-acting antibacterial and antiviral functions while the air permeability of the mask is not influenced, meanwhile, the problem of leaching effect of a metal nanoparticle modified mask is solved, the material is degradable, and the environmental pollution pressure caused by non-degradable petroleum-based fiber materials such as polypropylene and the like can be effectively relieved.
Owner:NANJING FORESTRY UNIV

A method for cryopreservation of elongated semen and its dilution

The invention discloses a preserved diluent of cranoglanis bouderius seminal fluid and a cryopreservation method of the cranoglanis bouderius seminal fluid. The preserved diluent is prepared from sugar, sodium salt, potassium salt, calcium salt, tyrosine, glycine, distilled water and an anti-freezing agent-dimethyl sulfoxide. The cryopreservation method comprises the following steps: selecting good male parent fish meeting the conditions to carry out seminal fluid collection, preserving in the preserved diluent in which neomycin sulfate and streptomycin are added, adopting a cooling rate which is -10.5 DEG C / 30 seconds, and putting the seminal fluid in liquid nitrogen for cryopreservation after reaching -150 DEG C; when unfreezing and recovering are needed, taking out the cyropreserved cranoglanis bouderius seminal fluid, adding a PBS (Phosphate Buffer Solution) of which the volume percentage is 0.65 to 0.7 percent as an unfreezing solution, and putting the cranoglanis bouderius seminal fluid in a water bath of which the temperature is 32 to 40 DEG C for rapid unfreezing and recovering. According to the technology disclosed by the invention, the durability of preservation time of the cranoglanis bouderius seminal fluid can be ensured, the protection effect of the seminal fluid is good, and sperms after preservation are high in survival rate and good in vitality.
Owner:SOUTH CHINA AGRI UNIV +2

Drug for treating dermatoses and preparation method and application thereof

The invention discloses a drug for treating dermatoses. The drug is prepared from, by weight, 55-120 parts of chloramphenicol, 120-200 parts of propylene glycol, 50-90 parts of water for injection, 0.5-1.5 parts of chlorpheniramine maleate, 200-280 parts of white vaseline, 160-220 parts of glycerol, 1.5-3 parts of miconazole nitrate, 0.2-0.5 part of triamcinolone acetonide acetate, 220-300 parts of natural fatty alcohol and 0.5-0.9 part of neomycin sulfate. The drug has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, purging fire and cooling blood, relieving swelling and pain and resisting bacteria and viruses, is used for treating the dermatoses such as acnes, pachulosis, sunburn, dermatophytosis and mosquito bites and has the advantages that the treatment effect is good and is quickly achieved, the cure rate is high, cost is low, no irritation is generated to skin, and scars are not prone to be left.
Owner:梁东荣

Enterotoxemia Weak-neomycin sulphate

The invention discloses an enteromtoxemia Weak-neomycin sulphate without side effect for many raisers, comprising the following components by weight: 5-20 g of neomycin, 2-12 g of substituted nitramisole, 0.05-0.5 g of diclazuril, 100-500 mg of K3, 50-150 mg of atropine and 70-90 g of anhydrous dextrose. The production process comprises the following steps of: putting the components according to the weight proportion in a three-dimensional mixer to primarily mix for 10-15 minutes at the temperature of 25 DEG C and the humidity of no higher than 30, and then adding a carrier to mix for 20 minutes, after mixing, filling in aluminum foil bags or plastic bottles as soon as possible, and finally sealing and packaging.
Owner:李大伟

Compound veterinary preparation for treating poultry enteritis type colibacillosis

The invention belongs to a composition for treating poultry enteritis type colibacillosis in veterinary medicines. The preparation consists of the following components in percentage by weight: 3.25 percent of neomycin sulfate, 0.81 percent of lactate TMP (trimethoprim lactate), 10 percent of glutamine, and 85.94 percent of auxiliary glucose, wherein neomycin sulfate, lactate TMP and glutamine are main drug components. The veterinary composition is used for treating poultry enteritis type colibacillosis. The processing process of the composition comprises the following steps: respectively crushing and screening each component, and accurately weighing according to the required proportion; mixing for 25 minutes; inspecting a semifinished product; subpackaging, packaging and inspecting the finished product. According to the usage method, the composition is drunk in a ratio of 1 percent, and four days are taken as a course of treatment. The composition has a remarkable curative effect on poultry enteritis type colibacillosis, is low in drug tolerance, safe and low-toxic, and has good popularization and application values.
Owner:QINGDAO AGRI UNIV

A method for solid-liquid separation of neomycin sulfate fermentation waste liquid

A method for solid-liquid separation of neomycin sulfate fermentation wastewater comprises the first step of adding chitosan to the neomycin sulfate fermentation wastewater to obtain fermentation wastewater subjected to first flocculation; the second step of adding the dissolved polyacrylamide to the wastewater subjected to the first flocculation, and stirring to obtain wastewater subjected to second flocculation; the third step of filtering the fermentation wastewater subjected to the second flocculation and obtained in the second step to obtain a solid matter; pressing the solid matter to obtain a formed filter cake to complete the the solid-liquid separation of the neomycin sulfate fermentation wastewater. According to the method for the solid-liquid separation of the neomycin sulfate fermentation wastewater, the filtration speed can be doubled by means of the combined effect of two flocculants of the chitosan and the polyacrylamide to obtain a clean filtrate. The solid matter in the wastewater is removed efficiently, the wastewater handling difficulty is greatly reduced, and the environment protection problems existing in production of enterprises for a long time are solved.
Owner:YICHANG SANXIA PHARMA

Compound neomycin sulfate soluble powder and production method thereof

The invention provides compound neomycin sulfate soluble powder and a production method thereof. The soluble powder is prepared by mixing neomycin sulfate, doxycycline hydrochloride, trimethoprim, atropine sulfate, astragalus root extract, silicon dioxide fine powder and anhydrous dextrose. The obtained neomycin sulfate soluble powder is compounded by using multiple components, and has the effects of greatly reducing diarrhea of livestock and poultry animals, quickly recovering health status and the like.
Owner:WUXI ZHENGDA POULTRY

A kind of treatment method of neomycin sulfate production wastewater

The invention provides a treatment method for neomycin sulfate production wastewater. The neomycin sulfate production wastewater after pretreatment in a production workshop is mainly divided into two types of wastewater: fermentation wastewater and extraction wastewater. After the fermentation wastewater passes through the ammonia distillation reactor to remove most of the ammonia, the advanced oxidation is used to reduce the titer of neomycin sulfate remaining in the wastewater, thereby reducing the inhibitory effect of the residual titer in the wastewater on the biochemical treatment, and the fermentation after the titer is removed The wastewater is treated with anaerobic biochemical treatment. After the anaerobic biochemical treatment, the fermentation wastewater and the extraction wastewater are mixed together and then subjected to two-stage A / O aerobic biochemical treatment and advanced treatment. Finally, the stable and efficient removal of various pollutants in the wastewater is achieved, and the effluent reaches "Water Pollutant Discharge Standards for Fermentation Pharmaceutical Industry" (GB21903-2008) Table 2 standard; this method adopts the classified collection and qualitative treatment of neomycin sulfate production wastewater; it has the advantages of reasonable process economy, high treatment efficiency, low treatment cost, Stable and reliable operation and other advantages.
Owner:河南君和环保科技有限公司

Preparation method, cultivation method and application of alcidodes juglans chao larva feed

The invention belongs to the technical field of cultivation of alcidodes juglans chao larva, and discloses a preparation method, a cultivation method and application of an alcidodes juglans chao larvafeed. The alcidodes juglans chao larva feed is prepared from 45-50g of mouse feed, 45-50g of protein powder, 25-35g of cellulose powder, 15-20g of yeast powder, 15-20g of agar powder, 8-15g of sucrose, 1.8-2.5g of methyl p-hydroxybenzoate, 0.4-0.8g of chloramphenicol, 0.4-0.8g of neomycin sulfate, 0.8-1.5g of vitamin C, 0.8-1.5g of choline chloride, 8-15g of oat powder, 5-10g of glucose, 5-10g ofcorn flour and 750-1000ml of distilled water. The alcidodes juglans chao larva feed is prepared by uniformly mixing the mouse feed, the protein powder, the oat powder, the corn flour, the agar powderand the like; and the feed is simple in preparation process and low in cost, and is beneficial to industrialization, standardization and standardization of alcidodes juglans chao breeding.
Owner:CHONGQING NORMAL UNIVERSITY

HPLC detection method of neomycin sulfate component in Qumixin cream

The invention belongs to the field of chemical detection, and in particular relates to an HPLC detection method for the neomycin sulfate component in Qumixin cream, including (1) chromatographic conditions and system applicability test (2) solution preparation (3) determination and other steps . The HPLC detection method of the neomycin sulfate component in Qumixin emulsifiable cream of the present invention has the advantages of simple operation, high detection efficiency, small error, strong specificity, relatively stable detection method, less affected factors, and wide applicability ; The accuracy, precision, specificity, detection limit, etc. of the method all meet the methodological verification requirements, and have strong practicability. The method is used to analyze the neomycin sulfate group in the Trimixin cream produced by various enterprises. The detection can be carried out separately, and the content of each component of neomycin sulfate can be detected quickly and accurately, which is beneficial to the determination of the samples of Trimethin cream produced by various enterprises.
Owner:GUANGDONG SHUNFENG PHARMA

A kind of thermosensitive gel eye drop and its preparation method and application

The invention discloses thermo-sensitive type gel eye drops, as well as a preparation method and application thereof. The eye drops comprise prescription active ingredients, gel matrix, a preservative, a metal ion chelating agent, an isoosmotic adjusting agent and water for injection, wherein the prescription active ingredients comprise neomycin sulfate and dexamethasone sodium phosphate; the gel matrix comprises poloxamer 407 and poloxamer 188; the preservative comprises benzalkonium bromide; the metal ion chelating agent is ethylene diamine tetraacetic acid; and the isoosmotic adjusting agent is sodium chloride. Preferably, the eye drops also comprise a moisturizing agent and a bioadhesive material. The eye drops, disclosed by the invention, have the following advantages: (1) administration is facilitated, the medicine liquid has adhesion, retention and sustained release effects on the surface of retina, the administration frequency can be reduced, the medicine loss can be reduced and the compliance of a patient can be improved; (2) the eye drops are simple in preparation process, low in cost and suitable for large-scale production; and (3) the eye drops have good antibacterial and anti-inflammatory effects, low irritability and high safety.
Owner:SOUTHWEST UNIV

Hair dye containing polysaccharide natural polyphenols,

The invention discloses a hair dye containing polysaccharide natural polyphenols. The hair dye comprises an agent A and an agent B in a mass ratio of 1: 1, wherein the agent B comprises the followingcomponents: 18-26% of hydrogen peroxide, 8-15% of oleyl alcohol, 8-15% of oleic acid, 8-15% of propylene glycol, 8-15% of isopropanol, 1-5% of sodium dodecyl sulfate, 1-5% of phosphoric acid and the balance of deionized water; a large number of phenolic hydroxyl groups in neomycin sulfate modified eriodictyol-7-O-glucoside can effectively prevent oxidative deterioration of 5, 6-dihydroxyindole, sothat the hair dyeing efficiency is improved; the neomycin sulfate modified eriodictyol-7-O-glucoside has ultraviolet absorptivity and can protect the skin from being injured by ultraviolet rays; thehair dye has no irritating to skin; and due to the introduction of neomycin sulfate, the dyed hair can release antibacterial drugs under specific conditions, and the hair dye has a certain antibacterial effect and does not affect the hair dyeing effect at the same time.
Owner:SICHUAN UNIV
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