174results about How to "Expanded antimicrobial spectrum" patented technology

The invention discloses a fresh keeping agent containing essential oil, for fruits, and an application. The fresh keeping agent for fruits is characterized by being compounded from lysozyme, tea polyphenols, nisin, essential oil A, essential oil B, Vc and distilled water in a certain proportion. According to the fresh keeping agent for fruits, disclosed by the invention, the essential oil is optimized to be used as a main component of the fresh keeping agent, so that the fresh keeping agent has excellent effects of bacteriostasis and oxidation resistance and is applied to corrosion resistance and fresh keeping of the fruits, the fresh keeping and storage period of the fruits can be greatly prolonged, the fruits are guaranteed to maintain original quality in the fresh keeping period, and the quality of the fruits is effectively guaranteed. The fresh keeping agent for the fruits, disclosed by the invention is simple in compounding method, and convenient to apply; and the fresh keeping agent is completely compounded from natural components, and harmful chemical substances are not added, so that the fresh keeping agent is safe and environmental-friendly, and has an important industrial value.

The invention belongs to the technical field of pork preservative technologies and relates to a natural chilled fresh pork preservative and a preparation method thereof. The natural chilled fresh pork preservative is characterized by being prepared from 4.4-5.2% of a bacteriostatic agent, 11-15% of a synergist, 30-35% of Chinese herbal medicine extract liquor and the balance water. The bacteriostatic agent proportionally comprises, by weight parts, nisin, natamycin, lysozyme, chitosan and propolis supercritical CO2 extract; the synergist proportionally comprises, by weight parts, acetic acid, vitamin C, vitamin E and sodium lactate; the Chinese herbal medicine extract liquor is made by adopting an ethanol extraction method for extracting, by weight parts, grape seeds, garlic, Flos Caryophylli, Cortex Cinnamomi, rosemary, pepper and ginger and compounding with oregano essential oil and crude tea extract liquor. The natural chilled fresh pork preservative has advantages of reasonable formulation, edible safety, simplicity of the preparation method, operational convenience in use and excellent preservative effects.

The invention discloses a veterinary suspension containing amoxicillin, colistin sulfate and prednisolone and a preparation method thereof. The veterinary suspension adopts the amoxicillin, the colistin sulfate and the prednisolone as active ingredients. The preparation method of the veterinary suspension containing the amoxicillin, the colistin sulfate and the prednisolone comprises the following steps of: (1) dissolving or dispersing a suspending agent, an antioxidant and a preservative in a hot dispersion medium to obtain a solution (A); (2) adding 40-80 percent of dispersion medium in a formula ratio in a colloid mill, starting the colloid mill, then slowly adding the solution (A) and adding a wetting agent while stirring after the solution (A) is fully added; (3) sequentially adding the amoxicillin, the colistin sulfate and the prednisolone after fully adding all the accessories, and grinding by adopting two alternate modes, i.e. an endless grinding mode and a non-endless grinding mode; and (4) detecting the grain fineness, stopping grinding when the grain fineness accords with the requirement, adding the dispersion medium to the formula ratio, mixing, canning, sealing and sterilizing to obtain the veterinary suspension containing the amoxicillin, the colistin sulfate and the prednisolone.

The invention relates to an anti-infection venous catheter and a preparation method thereof. The venous catheter comprises a conduit main body tube, a tip end and a tube seat, and preferably also comprises a connecting seat and a plurality of epitaxial tubes, wherein the parts retained in a human body are the conduit main body tube and the tip end; and an anti-infection medicament rifampicin, an anti-infection medicament minocycline or combination of the two are uniformly loaded on the conduit main body tube. The preparation method of the venous catheter comprises the following steps of: dissolving the anti-infection medicament or the medicament combination to form soak solution; soaking the conduit into the soak solution to fully soak medicaments into the conduit; and drying to remove solvent to prepare the anti-infection venous catheter. During use, the medicaments are slowly released to fulfill the anti-infection aim of the conduit and avoid infection of the conduit during retention in the human body in surgery.

The invention discloses mildewcide, a preparation method and application thereof in grain storage. The mildewcide comprises the following raw materials in parts by weight: 3-8 parts of sodium diacetate and 1-3 parts of potassium sorbate. The mildewcide is prepared by mixing and pulverizing the raw materials. The mildewcide is prepared by various mildewcides with synergistic effect based on a certain ratio, so the synergistic effect of the mildewcide can overcome limitation of a single preservative in mildew resistance efficacy, enlarge bacteriostatic efficacy and range and achieve efficient broad-spectrum bacteriostatic action and powerful synergistic and mildewproof effects after recomposing the mildewcide with single component. Meanwhile, the mildewcide of the invention has obvious mildewproof effect for high-moisture grain.

The invention belongs to the technical field of pharmaceutic preparation and discloses a compound ivermectin sustained release tablet and a preparation method thereof. The compound ivermectin sustained release tablet is prepared by 1 to 15 parts by weight of ivermectin, 20 to 50 parts by weight of albendazole, 110 to 153 parts by weight of diluents, 20 to 30 parts by weight of sustained-release materials, 0.5 to 0.7 part by weight of lubricating agents and an appropriate quantity of adhesion agents. The ivermectin, the albendazole, the sustained-release materials and the diluents are fully and uniformly mixed in a mixing machine to obtain a mixture, the uniformly mixed mixture is placed in a one-step granulator, the adhesion agents are sprayed to form particles, the particles are dried, the lubricating agents are added in the particles to be fully and uniformly mixed, and the particles are prepared into tablets in a tablet machine. The compound ivermectin sustained release tablet and the preparation method thereof have the advantages that the antibacterial spectrum is wide, the action time is long, the drug resistance can not be easily generated, and the curative ratio is high; compared with common compound tablets, the tablet has better therapeutic effect; and compared with simple recipe drugs, the compound ivermectin sustained release tablet has the advantages that the curative effect is remarkable, simultaneously the dosage is reduced, and the treatment costs are lowered.

The invention provides a fresh flower preservative. The fresh flower preservative comprises the following components in parts by mass: 25 to 35 parts of cane sugar, 15 to 25 parts of chitosan, 8 to 12 parts of propolis supercritical CO2 extracts, 4 to 6 parts of natamycin, 1.6 to 2.0 parts of citric acid, 0.8 to 1.2 parts of salicylic acid, 0.6 to 0.8 part of boric acid, 0.6 to 1.0 part of vitamin C, 0.5 to 0.7 part of vitamin E, 60 to 100 parts of traditional Chinese herbal medicine ethanol extracting liquid and the balance of ultrapure water, wherein the total parts are 1000 parts. The fresh flower preservative provided by the invention has a reasonable formula, safe and environmentally-friendly components, a good nutrition effect and an excellent broad-spectrum antibacterial effect, can effectively inhibit damage to fresh flowers by various microorganisms, greatly prolongs the freshness-retaining period of the fresh flowers, has significant color-protecting and color-improving effects, is simple in preparation method, and is simple and convenient to operate during use.

The invention discloses a response surface method optimal combined compounded plant source preservative and the application thereof. The preservative consists of a plant extract and a solvent, whereinevery mL of the preservative comprises 48.00mg of a green tea extract, 27.38mg of a scutellaria baicalensis extract, 57.37mg of a longan kernel extract and 44.21mg of a hill gooseberry fruit extract.The preservative disclosed by the invention has a good antibacterial preservative effect, the four plant extracts of the preservative have certain synergetic effects, antibacterial spectrums of a single plant can be widened, and the preservative has wide antibacterial spectrums and is capable of effectively inhibiting microorganisms such as escherichia coli, pseudomonas aeruginosa, staphylococcusaureus, bacillus subtilis, candida albicans and aspergillus niger. In addition, the preservative is prepared by using a response surface method, and interaction functions of compounding components can be relatively visibly reflected.

The invention discloses a method for eliminating bacterial pollution of tissue culture seedlings. The method comprises the following steps: step A, weighing the following raw materials in parts by weight: herba houttuyniae, aloes, small centipeda herb, folium artemisiae argyi, herba pogostemonis and garlic; mixing the raw materials and then pulping or mixing the raw materials, adding water for immersing for a period of time and pulping to obtain Chinese herbal medicine pulp; step B, adding the Chinese herbal medicine pulp into a certain amount of conventional culture medium in parts by weight; uniformly mixing and then carrying out high-pressure sterilization to obtain a pollution removing culture medium; step C, transferring polluted tissue culture seedlings into the pollution removing culture medium and culturing for 7 to 10 days; step D, repeating the step A to the step C until pollution of the polluted tissue culture seedlings is eliminated, so as to obtain pollution-removed culture medium seedlings; step E, transferring the pollution-removed culture medium seedlings into the conventional culture medium and continually culturing. The method disclosed by the invention has the advantages of good sterilization effect, small damages to the culture medium seedlings, low cost, and simplicity and convenience for operation, and is suitable for industrial popularization and the like.

A method for preparing a modified zein composite slow-release antibacterial liquid film. First, the zein is initially modified with ascorbic acid, then the zein is secondary modified with malic acid, and finally the zein is modified with citric acid. For the final modification of zein, add powdered sodium hydroxide to adjust the pH value, and keep warm to obtain the final modified zein film liquid; melt the beeswax and mix it with oleic acid, and add it to the final modified corn Stir evenly in the prolamin film liquid, cool to room temperature, then add nisin and emulsifier lecithin, homogenize, and obtain the modified zein compound slow-release antibacterial liquid film. The advantages are: good film-forming mechanical strength, safe and edible, and better slow-release performance, long-lasting antibacterial effect, can form a protective film on the surface of objects, and can be used for food preservation of fruits, vegetables, meat, seafood and nuts.

The invention discloses azoxystrobin-folpet compounded suspension agent and a preparation method thereof. The suspension agent comprises, by weight percent, 20-60% of azoxystrobin, 10-50% of folpet, 3-4% of wetting dispersing agent, 2-3% of dispersing agent, 3-4% of antifreezing agent, 0.2-0.3% of thickening agent, and the balance of water. The method includes firstly, weighing the azoxystrobin, the folpet, wetting dispersant, dispersant and the antifreezing agent by weight, adding water to obtain 95%, and mixing the above ingredients; secondly, grinding the mixed ingredients in a bead mill for 4-5 hours to obtain initial suspension agent; and thirdly, mixing the thickening agent and the water to obtain 5%, adding the mixture into the initial suspension agent, and using a mixer to mix at high speed for 2-4 hours to obtain the finished suspension agent. The suspension agent is made by compounding technology, antibacterial spectrum of the suspension agent is broadened, effect of the suspension agent is enhanced, toxicity of the suspension agent is lowered, and the suspension agent has the advantages of high active ingredient content, high suspending rate, high dispersiblity, high stability and the like.