The invention discloses a multipoint medical safety calling information system which comprises a plurality of bedside voice extension units, a plurality of doorway voice extension units, a plurality of medical voice extension units and a PC (personal computer) server. The bedside voice extension units are positioned on bedsides of patients, the doorway voice extension units are positioned at doorways of wards, the medical voice extension units are positioned at nursing stations or doctor offices, and the PC server is in communication connection with the bedside voice extension units, the doorway voice extension units and the medical voice extension units. Since the PC server is in communication connection with the bedside voice extension units, the doorway voice extension units and the medical voice extension units, multipoint calling requests of multiple patients is realized, the calling requests can be responded by multiple extension units, and the multiple calling requests can be subjected to priority setting by the PC server to guarantee that emergency calling requests can be handled timely, so that intelligence level of a medical calling system is promoted. Further, the PC server is connected with a hospital information system, patients can inquire relevant information such as medical expenses and friendly prompts by themselves, and information service functions of the medical calling system are expanded.