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Plant extract and synergist contained antimicrobial composition

A technology of synergist and plant extract, applied in detergent compositions, plant growth regulators, botanical equipment and methods, etc., can solve the problems that IPBC cannot be used in infant formula, dosage restrictions, and high iodine content , to achieve the effect of reducing possible risks, reducing dosage, and enhancing bacteriostatic ability

Active Publication Date: 2014-01-29
BEIJING SUNPU BIOCHEM TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, although IPBC is the most effective anti-mold agent, it usually only needs a few ppm to achieve a very good anti-mold effect; but due to its high iodine content, regulations restrict its use more and more. Strict, especially in the application of infant products, the EU's previous cosmetic regulations (Directive76 / 768 / EEC) and the latest cosmetic regulations [Regulation (EC) No1223 / 2009] stipulate that IPBC cannot be used for children under the age of three formula for infants and young children (except for bath products and shampoos), nor for body lotion and body cream products (contacting large areas of skin), and the dosage is also strictly limited

Method used

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  • Plant extract and synergist contained antimicrobial composition
  • Plant extract and synergist contained antimicrobial composition
  • Plant extract and synergist contained antimicrobial composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Table 1. The dosage of each formulation of the antimicrobial composition (% by weight)

[0035]

[0036]

Embodiment 2

[0038] The minimum inhibitory concentration (MIC value) of the 1#-8# compositions in Table 1 of Example 1 was determined by the plate coating method (for mold and yeast) and the dilution culture method (for bacteria), and the results are shown in Table 2.

[0039] Table 2. MIC values ​​(ppm)

[0040]

[0041] As can be seen from Table 2: the 1# and 5# formulations are comparative samples, and the MIC value of the 5# formulation is significantly reduced after adding synergists and plant extracts, such as the MIC for Escherichia coli from 650ppm to 500ppm. The MIC value of Candida dropped from 100ppm to 10ppm, and other strains had similar effects. 3# and 8# formulations are comparative samples. After adding synergists and plant extracts, 3# formulations have the same or slightly lower MIC values ​​against Aspergillus niger, Penicillium expanses and Candida albicans. Candida albicans Yeast as an example, the active content of IPBC in 3# and 8# formulations is 2.0%×70ppm and ...

Embodiment 3

[0043] The products of the "antimicrobial composition" of the present invention can be used in personal care products, including rinse-off products (such as facial cleanser, shampoo, shower gel, hand sanitizer, toothpaste, etc.) and leave-on products (such as creams, lotions, etc.) , toner, etc.); can also be used in household cleaning products (such as detergent, laundry detergent, leather care solution, floor polish, kitchen cleaner, etc.); can also be used in various wet wipes.

[0044] Table 3. Products containing the "antimicrobial composition" of the present invention

[0045]

[0046] "Antimicrobial composition" numbering and formula are the same as in Example 1. The data in the table represent the amount of the antimicrobial composition added in various products (personal care products, household cleaning products or wet wipes).

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PUM

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Abstract

The invention discloses a plant extract and synergist contained antimicrobial composition. The composition contains a plant extract (A), a synergist (B), a mildew preventive (C), an antiseptic (D) and a solvent (E). The composition disclosed by the invention has a good inhibiting effect on bacteria and fungi (molds nod saccharomycetes); through the synergistic effect of all the components, the consumption of the traditional chemical antiseptic IPBC (Iodopropynyl Butylcarbamate) or nipagin esters is remarkably reduced, the safety in using the composition is improved, the irritation is reduced, and the possible risks are reduced. Meanwhile, the antiseptic is compounded in the composition, so that the antibacterial spectrum of an antiseptic system of the composition is effectively expanded, and the bacteriostatic ability is enhanced.

Description

technical field [0001] The invention relates to an antimicrobial composition containing a plant extract and a synergist, which is mainly used for antisepsis and sterilization of microorganisms in personal care products, household cleaning products and wet wipes. Background technique [0002] Common microorganisms in products such as personal care products, household cleaning products and wet wipes mainly include bacteria and fungi (mold and yeast). In order to prevent the reproduction and growth of these microorganisms, a certain amount of preservatives and fungicides are generally required to be added. These antiseptics and bactericides should have good bactericidal and bacteriostatic effects on bacteria and fungi (mold and yeast), and at the same time have less irritation, higher safety and meet the requirements of laws and regulations. [0003] In the process of using antiseptics and fungicides, in order to increase their broad-spectrum antimicrobial properties, they gene...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N65/22A01N65/20A01N65/08A01P1/00A01P3/00A61K8/97A61Q19/10A61Q5/02A61Q11/00A61Q17/00C11D3/60C11D3/382C11D3/48A47K10/16
Inventor 蔡宏洋冯士清姚自奇张慧明刘春霞高学敏李平
Owner BEIJING SUNPU BIOCHEM TECH
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