The invention discloses a copper-base ceramic cylinder sleeve and a powder metallurgy preparation method thereof. The ceramic cylinder sleeve comprises, by weight, 18-31 parts of copper powder, 13-28 parts of nanometer copper oxide particles, 12-15 parts of graphene powder, 9-18 parts of titanium oxide, 14-31 parts of silicon carbide, 9-15 parts of silicon nitride, 10-22 parts of silicon dioxide, 5-14 parts of dispersing agent and 22-36 parts of water. Compared with the prior art, the copper-base ceramic cylinder sleeve and the powder metallurgy preparation method have the following beneficial effects that firstly, by means of the copper-base ceramic cylinder sleeve, metal powder and ceramic materials are mixed evenly through the powder metallurgy method, a blank is manufactured in an isostatic pressing manner, and accordingly it can be guaranteed that the cylinder sleeve obtained through preparing is even in material and not prone to crack; secondly, compared with a cylinder sleeve in the prior art, the abrasive resistance, tenacity, strength, thermal resistance and corrosion resistance of the copper-base ceramic cylinder sleeve are greatly improved, and the long service life is achieved; and thirdly, the preparation method of the copper-base ceramic cylinder sleeve is simple in technology, little in consumed energy and not prone to polluting the environment.