41 results about "Cartilago articularis" patented technology

The invention discloses a method for preparing a bionic porous tissue engineering cartilage scaffold. The decellularized Wharton gum suspension is mixed with chondroitin sulfate, and the mixing ratio of the Wharton gum suspension and chondroitin sulfate is 2.0:0.25-2.0:2.0 , add ethyl dimethylamine propyl carbodimethylamine again and mix thoroughly, place at room temperature 5-10 cm away from the light source for cross-linking under the irradiation of 258nm wavelength ultraviolet light; place the cross-linked scaffolds at low temperature successively The stent was shaped in a refrigerator, vacuum freeze-dried to obtain a shaped stent, stored in a sealed bag, sterilized by irradiation at 60°C, and stored at 4°C for use. The cartilage scaffold prepared by the present invention has the characteristics of bionic and multi-porosity, can induce stem cells to differentiate into chondrocytes in vitro, promote the expression of proteoglycan and type II collagen in the cartilage matrix, and can be used for constructing tissue-engineered articular cartilage in vitro, for repairing articular cartilage Defect provides high quality scaffold material.

The invention relates to healthcare noodles with mantis shrimps and a preparation method of the healthcare noodles with mantis shrimps. The healthcare noodles with mantis shrimps are prepared from the raw materials in percentage by weight according to a formula: 65-80% of flour, 5-10% of mantis shrimp enzymatic protein powder, 1.9-2.5% of glucosamine hydrochloride, 8-12% of zanthoxylum armatum DC leaves, 5-10% of sambucus williamsii leaves and 0.1-0.5% of abelmoschus manihot gum. All the raw materials are prepared into noodles through processing means with various approaches. Not only is the problem that mantis shrimp enzymatic protein powder can not be used as a food matrix because of having obvious bitter and fishy smells solved, but also the antibacterial, anticorrosion and fresh-keeping capacities of the noodles are also improved, and meanwhile, the healthcare value of the noodles is higher. In addition, the healthcare noodles with mantis shrimps is strong in fragrance, delicious in flavor, chewy, tough and elastic in chewing, good in boiling fastness and long in storage life. If being taken for a long term, the healthcare noodles with mantis shrimps can achieve the effects of regulating the physical function, resisting to diseases, bodybuilding and prolonging life and also have the effects of increasing the viscidity of synovial fluid, improving the cartilago articularis metabolism and strengthening tendons and bones. In addition, wastes are utilized comprehensively, so that the healthcare noodles with mantis shrimps have huge societal, ecological, environmental and economic benefits.

The invention discloses a polypeptide R1-P1 for adjusting FGFR1 (Fibroblast Growth Factors Receptor 1) activity. The polypeptide can be combined with the FGFR1 specificity, has an obvious adjusting function for the FGFR1 activity and can obviously restrain the activity of p-ERK in the main downstream signal path MAPK of FGFR1; after the R1-P1 peptide is articular injected to DMM model mouse, the regression of cartilago articularis and the loss level of matrix are obviously reduced; the process of arthritis is delayed. The polypeptide has the advantages of small molecular weight, simple preparation, controllable quality, low immunogenicity, and the like, can be used for preparing the drugs for relieving or treating osteoarthritis and has an excellent potential application value.