170 results about "Polyacrylamide Hydrogel" patented technology

The invention discloses a preparation method for sodium alginate-acrylamide-based hydrogel. The preparation method comprises the following steps of: dissolving sodium alginate powder in deionized water; then sequentially adding an acrylamide monomer, a methylene diacrylamide cross-linking agent, ammonium persulfate and an N,N,N',N'-tetramethylethylenediamine catalyst; uniformly stirring the materials, pouring the mixture into a glass die, and heating the mixture to obtain a hydrogel; completely soaking the hydrogel in a 0.01-1 mol / L non-monovalent cation aqueous solution for 1-10 hours, wherein cations diffuse and enter in a hydrogel network structure, and induce sodium alginate to cross-link, so as to generate the high-strength and high-toughness sodium alginate-acrylamide-based hydrogel during the process. The hydrogel disclosed by the invention has the following performances: the highest tensile strength can achieve 1 MPa, and the highest tensile elasticity modulus can achieve 250 KPa; a loading-unloading test is performed on the hydrogel, and when the great tensile multiple before unloading is 8, the highest dissipated energy can achieve 2180 KJ / m<3>.

A hydrogel for use as a prosthetic device for supplementing, augmenting or replacing cartilage in the intra-articular cavity of a joint and for treatment or prevention of arthritis. The hydrogel may be a polyacrylamide hydrogel obtained by combining acrylamide and methylene bis-acrylamide. A prosthetic device comprising the polyacrylamide hydrogel is also disclosed.

A hydrogel for use as a prosthetic device for supplementing, augmenting or replacing cartilage in the intra-articular cavity of a joint and for treatment or prevention of arthritis. The hydrogel may be a polyacrylamide hydrogel obtained by combining acrylamide and methylene bis-acrylamide. A prosthetic device comprising the polyacrylamide hydrogel is also disclosed.

The invention discloses graphene aerogel and a hybrid composite material thereof as well as a preparation method and application of the of graphene aerogel. The preparation method comprises the following steps: 1) mixing graphene oxide, a reducing agent, acrylamide, N,N-methylene-bisacrylamide and potassium persulfate and reacting to obtain partially-reduced graphene / polyacrylamide hydrogel; 2) carrying out pre-freezing and reduction on the partially-reduced graphene / polyacrylamide hydrogel in sequence to obtain graphene / polyacrylamide hydrogel; 3) dialyzing and drying the graphene / polyacrylamide hydrogel in sequence to obtain the graphene aerogel. The graphene aerogel has the characteristics of uniform cellular structure and light weight, excellent resilience, relatively high mechanical strength and good solvent resistance; a preparation process is simple, rapid and low in cost; the graphene aerogel can also be used for preparing polymer / graphene composite aerogel, nanoparticle / graphene composite aerogel and polymer / graphene composite materials and the like, so that application of the graphene aerogel is expanded.

The present invention relates to a bio-stable hydrogel for use in the treatment and prevention of incontinence and vesicouretal reflux. The hydrogel is obtainable by combining acrylamide and methylene bis-acrylamide in amounts to provide about 0.5 to 25% by weight polyacrylamide, based on the total weight of the hydrogel.

The present invention relates to a mammary prosthesis made of polyacrylamide hydrogel. Said prosthesis include a shell which is made of medical high polymer elastic material, such as silicone, and said shell have a round curved surface. The shell is filled with polyacrylamide hydrogel, or with hydrogel powder, and the weight of the filled powder is matched with the volume of the circular shell, that is to say, each 100 ml volumes of the shell could be filled with about 2.5–5 g hydrogel powder.

A process which allows for the preparation of a substantially uniform hydrogel, such as a polyacrylamide hydrogel, wherein the uniformity of the hydrogel, in terms of the rheological properties, is established by limiting the temperature differential in the reaction process to a very narrow range, such as no more than 5° C. This process allows for polymers novel in their uniformity also by means of being suitably a continuous process. A continuous process for the preparation of a substantially uniform hydrogel, such as a polyacrylamide hydrogel, led to high uniformity by preventing unreacted monomers, such as acrylamide, from surpassing the gel front in the pipe reactor. This was achieved by use of a static mixer. Polymer hydrogels are rendered biocompatible by means of a novel washing process wherein the polymer specific surface area is appropriately set.

The invention discloses a photonic crystal thin film as well as a preparation method and application thereof. The photonic crystal thin film comprises Fe3O4 nanoparticles and polyacrylamide hydrogel, and the Fe3O4 nanoparticles are uniformly dispersed in the 1mg / ml-50 mg / ml polyacrylamide hydrogel. The preparation method comprises the following steps: (1) uniformly dispersing Fe3O4 nanoparticles, acrylamide, methene acrylamide and photon initiator into an organic solution, to obtain a hydrogel photon crystal suspension; (2) paving the hydrogel photon crystal suspension into a 150-300mu m thin film, loading a magnetic field of 300-2000 gaussian so as to develop the thin film, and then curing; and (3) soaking the cured crystal thin film in water, and replacing the organic solvent, thus obtaining the photonic crystal thin film. The thin film has sensitive solvent response and mechanical response capability, the preparation is fast, and the photonic crystal thin film can be used for naked-eye detection.

A hydrogel is obtained by combining acrylamide and methylene based-acrylamide, radical initiation and washing with pyrogen-free water or saline solution to give less than 3.5% by weight polyacrylamide, based on the total weight of the hydrogel. The hydrogel may be used as a soft tissue filler endoprosthesis. Also disclosed is a method of filling a soft tissue in a mammal using the endoprosthesis, and a prosthetic device comprising the polyacrylamide hydrogel.

The invention discloses prussian blue nano-scale hollow olivary microballoons, and belongs to the technical field of prussian blue materials. A preparation method of the prussian blue nano-scale hollow olivary microballoons comprises the following steps that 1, acrylamide as a monomer, N,N'-methylenebisacrylamide as a cross-linking agent, ammonium persulfate as an initiator and ethanol as a solvent are prepared into crosslinked polyacrylamide hydrogel microballoons by a dispersion polymerization technology; 2, hydrogel microballoon / ethanol suspending liquid is added with a Fe<3+> salt aqueoussolution; 3 the mixed solution obtained by the step 2 is stirred violently for one night so that the crosslinked polyacrylamide hydrogel microballoons swelled by Fe<3+> deform; 4, a potassium ferrocyanide aqueous solution is added dropwisely into the mixed solution treated by the step 3 to form prussian blue shells; and 5, the solvent is removed so that the prussian blue nano-scale hollow olivarymicroballoons are obtained. The preparation method of the prussian blue nano-scale hollow olivary microballoons has the advantages of simple operation, low cost, good adaptability for large-scale production, and controllability of microballoon sizes. The prussian blue nano-scale hollow olivary microballoons have nano-scale short axis sizes and micron-scale long axis sizes, and can be utilized widely for drug slow release, sensors, electrode materials and the like.

A polyacrylamide hydrogel includes co-polymerized acrylamide, bisacrylamide and N-hydroxyethylacrylamide

The invention discloses a hydrogel antifouling fiber, a preparation method of hydrogel antifouling fiber and a preparation method of an implanted type high-strength hydrogel antiflouling coating layer, and relates to antiflouling materials, preparation methods of the antiflouling materials, and preparation methods of vessel antifouling coating layers, for mainly solving the technical problems that the conventional PVA (Polyvinyl Acetate) fiber implanted type vessel antiflouling coating layer is poor in antifouling effect and short in service life. The hydrogel antifouling fiber disclosed by the invention is a fiber with a core-shell structure, the shell layer of the fiber is made of polyacrylamide, and the core layer is made of carbon nano tube modified polyacrylamide. The preparation method comprises the following steps: 1, preparing polyacrylamide hydrogel, 2, preparing a core layer spinning dope, 3, preparing a shell layer spinning dope, 4, spinning by using a wet method to obtain the hydrogel antifouling fiber. The preparation of the antifouling coating layer comprises the following steps: spraying implantation gel onto a substrate, further implanting the hydrogel antifouling fiber into the substrate through a high-pressure static implantation technique, and drying to obtain the implanted type high-strength hydrogel antifouling coating layer. The coating layer is not changed when being soaked in seawater or industrial water for 6 months, so that the coating layer can be applied to vessel antifouling.

The invention discloses a compressible rechargeable zinc-manganese battery and a battery-sensor integrated device based on the battery. The compressible rechargeable zinc-manganese battery comprises apositive pole, a negative pole and an electrolyte, wherein the negative pole is made from a zinc element based active material, and a positive pole active material is manganese dioxide; the electrolyte is a crosslinked polyacrylamide hydrogel electrolyte. The synthetic method for crosslinked polyacrylamide hydrogel electrolyte is as follows: 3-5 g of monomeric acrylamide, 25-35 mg of an ammoniumpersulfate initiator and 3-5 mg of N'N-dimethyl bis acrylamide are added into 15-25ml of deionized water, and stirring continues till clarification is achieved; then a clear solution is transferred to a glass watch glass and then is coated with tin foil paper, and reaction is executed at 50-70 DEG C for 50-70 minutes to obtain a hydrogel; finally, the hydrogel is fully soaked in 0.8-1.2 mol / L ofzinc sulfate and 0.05-0.15 mol / L of manganese sulfate electrolyte to obtain the crosslinked polyacrylamide hydrogel electrolyte. The battery can adapt to large compressive stress while maintaining energy storage performance, and flexibility and elasticity of an energy storage device can be achieved.

The present invention relates to a method for preparing a natural or synthetic polymer hydrogel loading graphene oxide or graphene, and to the selective and high-capacity adsorption and loading of the hydrogel with respect to a low-molecular weight material or a high-molecular weight material. More specifically, an alginate or polyacrylamide hydrogel loading graphene and a graphene derivative is prepared, wherein the hydrogel can be controlled to enable selective absorption according to the characteristics of an adsorbate by adjusting the reduction degree of graphene oxide, exhibits high adsorption capacity, and is easy to handle as a hydrate. These characteristics can significantly improve the adsorption efficiency with respect to a material in water or an organic phase material, compared with existing hydrogels.

The invention discloses bionic construction of a metal-foam-based oil-water separation material and belongs to the technical field of functional materials. A bionic construction method comprises the following steps of: pre-treating metal foam; preparing a polyacrylamide hydrogel; immersing the metal foam into the polyacrylamide hydrogel; and irradiating the metal foam to which the polyacrylamide hydrogel is adhered under ultraviolet light, taking out, cleaning by using deionized water, drying and the like. The preparation method is simple; and by the slight corrosion of nitric acid and the adhesion of the polyacrylamide hydrogel, the metal surface becomes a super-oleophobic / super-hydrophilic surface, so that the material achieves an oil-water separation effect.

The invention discloses a preparation method for sodium alginate-acrylamide-based hydrogel. The preparation method comprises the following steps of: dissolving sodium alginate powder in deionized water; then sequentially adding an acrylamide monomer, a methylene diacrylamide cross-linking agent, ammonium persulfate and an N,N,N',N'-tetramethylethylenediamine catalyst; uniformly stirring the materials, pouring the mixture into a glass die, and heating the mixture to obtain a hydrogel; completely soaking the hydrogel in a 0.01-1 mol / L non-monovalent cation aqueous solution for 1-10 hours, wherein cations diffuse and enter in a hydrogel network structure, and induce sodium alginate to cross-link, so as to generate the high-strength and high-toughness sodium alginate-acrylamide-based hydrogel during the process. The hydrogel disclosed by the invention has the following performances: the highest tensile strength can achieve 1 MPa, and the highest tensile elasticity modulus can achieve 250 KPa; a loading-unloading test is performed on the hydrogel, and when the great tensile multiple before unloading is 8, the highest dissipated energy can achieve 2180 KJ / m<3>.

The invention discloses a chitosan polyacrylamide hydrogel base material and a preparation method thereof. The chitosan polyacrylamide hydrogel base material is composed of an acrylamide solution, a methylene diacrylamide solution, H2O, an ammonium persulfate solution, tetramethyl ethylenediamine and a chitosan solution. The preparation method of the chitosan polyacrylamide hydrogel base material comprises a step of mixing and stirring, a step of transferring to a glass clamping plate for reacting, and a step of immersion. The chitosan polyacrylamide hydrogel base material has a simple technology and allows hydrogels having different hardnesses to be obtained, and the obtained hydrogels have the advantages of non-toxicity, easy adherence growth of cells, reduction of the reaching complexity of the cytomechanics, benefiting for the researches on the mechanical properties of the cells, and reduction of the researching cost.

The invention discloses an adsorption film for synchronously fixing various oxygen-containing negative ions and a preparation method thereof, and belongs to the technical field of gradient diffusion films. The adsorption film is a polyacrylamide hydrophilic gel film with zirconium dioxide particles uniformly distributed on the surface, and the particle size of the zirconium dioxide particles is not more than 0.3 micron. The preparation method of the absorption film comprises the following steps: step 1, preparing the polyacrylamide hydrophilic gel film; step 2, placing the polyacrylamide hydrophilic gel film obtained from the step 1 in a zirconium ion-containing solution for standing; step 3, washing the film obtained from the step 2 by pure water, placing the film in a buffer solution, shaking the film in the buffer solution for 20-60 minutes, taking out, washing by the pure water, and soaking in the pure water for 6-12 hours to obtain the absorption film. The preparation method is simple, few absorption materials are used, the distribution uniformity is good, and the resolution ratio of the gradient diffusion film technology in oxygen-containing negative ion analysis can be remarkably increased.

An alginate-polyacrylamide IPN hydrogel formulation for 3D printing using a dual syringe system where the components that initiate polymerization of each network remain separated until printing. The dual syringe system may use a single motor and mixing head to combine both parts of the hydrogel formulation for controlled polymerization of the material. The elastic and time-dependent viscoelastic properties (stress relaxation) are tuned to match mammalian tissues by changing the crosslink density and monomer concentration. The fracture energy of the material may be increased by soaking in a calcium chloride solution. The resulting IPN polymer material may find application in soft tissue medical simulation devices, particularly because the mechanical properties may be tuned to mimic the elastic and viscoelastic properties of muscle tissue and may be 3D printed in the shape of anatomical parts.

The invention relates to a preparation method of a composite carboxymethyl chitosan / graphene oxide / polyacrylamide hydrogel. The preparation method includes the steps of adding CMCTs (carboxymethyl chitosan) in a GO (graphene oxide) solution, stirring, adding AM (acrylamide), and stirring to obtain a CMCTs / GO / AM dispersion solution; under the conditions of stirring and ice-water bath, adding an initiator solution and an accelerating agent into the dispersion solution, and stirring to obtain a mixed solution; placing the mixed solution in a container, vacuumizing, inflating nitrogen, sealing, and reacting at a room temperature for 8-12 hours to obtain the composite carboxymethyl chitosan / graphene oxide / polyacrylamide hydrogel. The preparation method is simple in preparing process, easy to operate and beneficial to industrial production; the prepared composite carboxymethyl chitosan / graphene oxide / polyacrylamide hydrogel is high in biocompatibility, mechanical property and toughness, can be used for artificial skin, artificial ligament and the like and has a potential application value in histological engineering.

The invention relates to a method for preparing a base bionic viscous polyacrylamide hydrogel system, comprising preparation methods of adenine viscous hydrogel, guanine viscous hydrogel, thymine viscous hydrogel, cytosine viscous hydrogel and uracil viscous hydrogel; bases include adenine, guanine, thymine, cytosine and uracil. The bases comprised in living organisms are introduced to the polyacrylamide hydrogel system, and base molecules are used as viscous expression groups, so that the system is imparted good viscosity; the prepared polyacrylamide hydrogel system is viscous to metals, glasses, plastics, rubbers and ceramics; the hydrogel preparation method solves the defect that traditional polyacrylamide hydrogel is low in viscosity.

The invention relates to preparation and application of high strength anti-tear magnetic hydrogel. The preparation is as below: dissolving acrylamide monomer and a sodium alginate powder in a sodium alginate@Fe3O4 magnetic fluid, adding a crosslinking agent and an initiator to obtain a polyacrylamide hydrogel penetrated by a sodium alginate@Fe3O4 polymer chain and a free sodium alginate polymer chain; immersing the obtained hydrogel in an aqueous solution containing Mn<+> multivalent cations to diffuse Mn<+> into the hydrogel, crosslinking the sodium alginate@Fe3O4 and free sodium alginate polymer chain by electrostatic interaction to obtain the Fe3O4@(M-sodium alginate / polyacrylamide)magnetic hydrogel, which has high mechanical properties (tensile strength up to 1.0MPa, the maximum elongation at break of up to 11 times, compressive strength of up to 5.0MPa, and the maximum energy to break up to 2800J / m<2>), and is insensitive to the crack (the maximum elongation at break of the sample containing cracks up to 9 times). The high strength anti-tear magnetic hydrogel can be applied to magnetic medical catheters.

The invention provides a method for improving the adhesion property of a polyacrylamide hydrogel, and resulting polyacrylamide hydrogel. The method comprises the following steps: (1) uniformly mixingdopamine grafted and modified hyaluronic acid or hyaluronate and a soluble tetraborate in deionized water to form a first crosslinked network; and (2) adding acrylamide and a crosslinking agent, thenadding an initiator and tetramethylethylenediamine under ice bath conditions, performing uniform mixing, and then polymerizing the obtained mixture at 0-4 DEG C to obtain the polyacrylamide hydrogel,wherein in step (1), the dopamine graft rate of the above modified product is 30-32%, and a mass ratio of the modified product to the tetraborate is 5:(2-1); and a mass ratio of the acrylamide added in step (2) to the modified product in the step (1) is (18-20):1, and the hyaluronate is a potassium salt or a sodium salt. The method greatly improves the adhesion property of the prepared polyacrylamide hydrogel.

The invention relates to an ultraphonic elastic imaging body model comprising polyacrylamide hydrogel and a scatterer, wherein the polyacrylamide hydrogel forms a reticular structure to wrap the scatterer. The elasticity (or the rigidity) of the ultraphonic elastic imaging body model can be freely regulated within a larger range by regulating the concentration of an acrylamide monomer and the sound attenuation coefficient can be changed to accord with the standard of ultraphonic elastic imaging by regulating the proportion of the scatterer.

The invention relates to a preparation method of double-network hydrogel based on coordination crosslinking and hydrophobic association crosslinking. The polyacrylamide hydrogel is formed by adoptingan AIBN thermal initiation mode, and a coordination bond is formed by adopting a post-coordination crosslinking mode, so that the double-network polyacrylamide hydrogel containing coordination crosslinking and hydrophobic association crosslinking mechanisms is formed. The preparation method does not need light shielding operation, and the selected initiator has moderate solubility in water and anoil phase; polymerization inside and outside the micelle is initiated at the same time, and a coordination bond is formed in a metal salt soaking manner after molding. The method has the advantages ofeasily available monomers, simple process and high polymerization rate, and the obtained hydrogel has excellent mechanical properties and structural stability.

The invention relates to the technical field of flexible sensor materials, particularly to an anti-freezing self-repairing conductive hydrogel and a preparation method thereof, and a flexible sensor. According to the preparation method, a conductive nanofiller / nanocellulose / polyacrylamide hydrogel is soaked in a composite modifier aqueous solution containing an anti-freezing agent and a metal salt, wherein the metal salt cooperates with the anti-freezing agent component to replace water molecules in a hydrogel network system, so that the freezing point of water in a composite hydrogel network structure is reduced, and the freezing resistance is improved; metal cations and cellulose in the composite hydrogel form reversible ionic bonds, the cellulose and polyacrylamide form reversible hydrogen-bond interaction, and the prepared hydrogel is endowed with excellent self-repairing performance through a formed multiple reversible network; and the metal salt cooperates with the conductive nano-filler to endow the prepared hydrogel with excellent conductivity, sensitive sensing performance and mechanical flexibility meeting the requirements of corresponding application scenarios.

Systems and methods which provide a polyacrylamide (PAM) based flexible and rechargeable zinc-ion battery (ZIB) configuration are described. Embodiments of a ZIB configuration comprise a PAM based polymer electrolyte. For example, a ZIB configuration of embodiments may comprise a manganese-dioxide (MnO2) cathode, a zinc (Zn) anode, and a PAM based polymer electrolyte. The PAM based polymer electrolyte may comprise a PAM based polymer hosting one or more solutions to form a hydrogel electrolyte (e.g., crosslinked polyacrylamide hydrogel electrolyte). For example, the PAM based polymer electrolyte may be configured as a polyelectrolyte matrix host for the one or more solutions, such as may comprise a neutral solution of zinc sulfate and manganese sulfate, to achieve a stable electro chemical performance under the repetitive deformation conditions.

The preparation method of medical polyacrylamide aquogel is characterized by that according to the medical application of aquogel, specially to the application of internal damaged region to be filledwith said aquogel and special requirements of acrylamide monomer low residue in said aquogel said invention uses organic solvent to extract the aquogel obtained when the polymerization reaction is completed, at the same time uses ultrasonic wave to make radiation so as to quickly and competely remove the acrylamide monomer from it so as t obtain the invented medical polyacrylamide aquogel.

The invention discloses a small-caliber bionic blood vessel with a three-layer structure and a manufacturing method thereof. Knitted silk fiber is adopted as an inner layer of the bionic blood vesselto simulate the structure and properties of human body blood vessel collagen, electrostatic spun polyurethane fiber serves as an outer layer to simulate the structure and properties of blood vessel elastin. In addition, polyacrylamide hydrophilic gel is also adopted as a middle layer to further improve the elasticity of the bionic blood vessel, meanwhile improve the bursting pressure of the bionicblood vessel and prevent blood permeation in the use process. The microcosmic three-layer structure of the human blood vessel can be simulated, and the special nonlinear mechanical properties of thehuman blood vessel can be also simulated. In addition, the raw materials for the bionic blood vessel have good cytocompatibility, are degradable and are suitable for blood vessel repair and regeneration in tissue engineering. Therefore, the small-caliber bionic blood vessel with the three-layer structure has a high potential practical value.

The invention belongs to the technical field of electrochromic devices, and discloses a functional hydrogel-based electrochromic device and a preparation method thereof. The method comprises the following steps: using acrylamide as a monomer, N,N-dimethylbisacrylamide as a cross-linking agent, ammonium persulfate as a thermal initiator, 4-hydroxy-2,2,6,6-tetramethylpiperidine oxide as a catalyst to prepare polyacrylamide hydrogel; adding a solution having electrolyte, electro-alkali, and base-responsive molecules to the hydrogel at room temperature, and adsorbing the solution by the swelling action of the hydrogel to obtain a functionalized hydrogel; and sandwiching the hydrogel between two ITO glass electrodes to obtain a functional hydrogel-based electrochromic device. The functional hydrogel-based electrochromic device and the preparation method thereof are simple in preparation process, mild in working condition, use water as a solvent to reduce the harm to the human body, which isenvironmentally friendly, good in reproducibility, and very suitable for industrial production.