298 results about "Reticular formation" patented technology

In one embodiment, a neck bridge for bridging the neck of an aneurysm includes a junction region, a number of radially extending array elements attached to the junction region, and a cover attached to one or both of the junction region and an array element. The array elements are configured to be positioned within the aneurysm after the neck bridge is deployed from a delivery device. In a second embodiment, the neck bridge includes a junction region and a braided or mesh-like structure secured to the junction region. The braided or mesh-like structure is made from an elastic material.

Porous biocompatible structures suitable for use as medical implants and methods for fabricating such structures are disclosed. The disclosed structures may be fabricated using rapid manufacturing techniques. The disclosed porous structures has a plurality of struts and nodes where no more than two struts intersect one another to form a node. Further, the nodes can be straight, curved, portions that are curved and / or straight. The struts and nodes can form cells which can be fused or sintered to at least one other cell to form a continuous reticulated structure for improved strength while providing the porosity needed for tissue and cell in-growth.

Methods for restoring blood flow in occluded blood vessels using an apparatus having a self expandable distal segment that is pre-formed to assume a superimposed structure in an unconstrained condition but can be made to take on a volume-reduced form making it possible to introduce it with a microcatheter and a push wire arranged at the proximal end, with the distal segment in its superimposed structure assuming the form of a longitudinally open tube and having a mesh structure of interconnected strings or filaments or struts. In a preferred embodiment, the distal segment has a tapering structure at its proximal end where the strings or filaments or struts converge at a connection point.

An improved medical lead assembly and method of use is provided. The lead assembly includes a lead body, and a spring member positioned adjacent to the lead body. The spring member may be deployed a selectable amount to maintain the lead body in a fixed location within a patient's body. The spring member may be an expandable coil, a mesh structure that is similar to a stent, or any other similar device that may be positioned in a low-profile state during a lead implant procedure. After the lead is positioned at a target destination, the spring member may be deployed an amount that is selected based on the characteristics of the surrounding tissue, including vessel size. According to one aspect of the invention, the lead assembly may provide means for facilitating chronic lead extraction.

A positionable internal retraction device is provided comprising a malleable ring member and a web-like structure. The retraction device operates to temporarily reposition tissues and organs from an operative site to provide a clear access and visual path for the surgeon. The ring member may be elongated, twisted, folded, bent or deformed to provide an appropriate insertion profile and subsequent functional shape. The retraction device may be shaped for both open and minimally invasive surgeries. The retraction device is atraumatic and may be used for retraction of delicate tissues and organs. The ring member may have different bending biases. The web-like structure may be constructed of any elastic material that can stretch and recover from the shaping and reshaping of the ring member. In another aspect of the invention, the ring member further comprises an internal lumen defining a wall, which may be of any geometric shape providing a desired bending bias. The ring member may further include a reinforcement member placed within the lumen and made of a “shape memory” material that allows the reinforcement member to return to its desired shape or condition after being bent. The reinforcement member may be placed in some sections of the ring member to keep these sections substantially straight. Each of the ring member, the reinforcement member and the internal wall may have a cross-section or profile of any geometric shape to provide a desired bending bias in a preferred plane. In yet another aspect of the invention, the ring member further comprises a second lumen and a second reinforcement member placed within the second lumen to provide a desired bending bias.

A medical implant, having a proximal and a distal end, that is preformed to assume a superimposed structure at an implantation site but can be made to take on a volume-reduced form making it possible to introduce it by means of a micro-catheter and a guide wire arranged at the proximal end, with the implant in its superimposed structure assuming the form of a longitudinally open tube and having a mesh structure of interconnected strings or filaments. The implant has a tapering structure at its proximal end where the strings or filaments converge at a connection point.

The present invention is directed to systems for occluding an aneurysm having an aneurysmal neck and an aneurysmal inner wall. Generally, a device in accordance with the present invention includes a mesh-like structure that is integrally composed of a shape-memory alloy such as NiTi. The device is deployed within the aneurysm through the aneurysmal neck. The device is configured to be in a deployed state and an undeployed state, and is configured to transition from the undeployed state to the deployed state by exposure to a higher temperature and / or by being unconstrained. The device may function to retain finer vaso-occlusive devices such as vaso-occlusive coils and / or embolic liquids. Furthermore, the device itself may function as a vaso-occlusive device.

An implant, including a web structure having a space truss with two or more planar truss units having a plurality of struts joined at nodes is used to join two separated bone portions. The web structure is configured to be disposed in the space between the separated bone portions to enhance fusion. In some embodiments, the implant comprises a non-planar surface.

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Provided is a surgical graft having one or more pockets adapted to receive a shaft tip of a surgical fastening device. The graft of the invention may be made from a biodegradable material, a biological material, a non-biodegradable material, biodegradable material, or a combination of any of these. The graft may be of a mesh construction, and may have an elongated shape, or may be shaped as a patch. The graft may be used, for example, in a method for treating urinary incontinence, vaginal vault repair, posterior vaginal wall prolapse, anterior vaginal wall prolapse and inguinal hernia. The invention also provides a system including a surgical graft of the invention, one or more surgical fasteners, and a surgical fastening device having a shaft and configured to eject at least one of the surgical fasteners from the tip of the shaft.

Various embodiments of implant systems and related apparatus, and methods of operating the same are described herein. In various embodiments, an implant for interfacing with a bone structure includes a web structure, including a space truss, configured to interface with human bone tissue. The space truss includes two or more planar truss units having a plurality of struts joined at nodes. Implants are optimized for the expected stress applied at the bone structure site.

In various embodiments, an implant for interfacing with a bone structure includes a web structure including a space truss. The space truss includes two or more planar truss units having a plurality of struts joined at nodes and the web structure is configured to interface with human bone tissue. In some embodiments, a method is provided that includes accessing an intersomatic space and inserting an implant into the intersomatic space. The implant includes a web structure including a space truss. The space truss includes two or more planar truss units having a plurality of struts joined at nodes and the web structure is configured to interface with human bone tissue.

A medical device for treatment of a stenosed body lumen, includes an open-ended cylindrical body carried on a distal end of a catheter for insertion of the device into the body lumen and placement at the stenosed site. The cylindrical body is movable between a collapsed position for insertion into the body lumen, and a radially expanded position pressed against the wall of the body lumen. In one embodiment the body sidewall is formed by a plurality of interconnected struts or elements defining openings therebetween, and at least one elongate ribbon is attached to an outer surface thereof for carrying a therapeutic agent. In another embodiment, the body is formed of interwoven elements defining a mesh-like structure, and the elements may comprise dissimilar materials, such as, e.g., copper and silver. In a further embodiment the body is formed of layers of different materials such as, e.g., copper, silver, and / or steel, laminated together. In a still further embodiment the device is designed for temporary placement of the catheter and body in a body lumen for treatment of a stenosed site, after which the catheter and body are withdrawn. In all forms the body may have an outwardly flared inlet end to reduce turbulence of fluid flowing through it, and / or a gel-like coating of a cholesterol-dissolving or blood clot dissolving agent may be placed on the device.

Expandable stent for insertion into a body passage having a mesh structure of interconnecting portions (6) joined together by joining portions (5). The stent, when inserted into said body passage, is adapted to dissolve into smaller parts, wherein the joining portions dissolve faster than the interconnecting portions. In a preferred embodiment the joining portions are made from a first material and the interconnecting portions are made from a second material different from said first material, wherein the first material dissolves faster than said second material.

Systems and methods for treating thrombosis and or emboli in a peripheral vasculature of a patient are disclosed herein. The method can include providing a thrombus extraction device including a proximal self-expanding coring portion formed of a unitary fenestrated structure and a distal expandable tubular portion formed of a braided filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus in a vessel; deploying the thrombus extraction device from the catheter from a constrained configuration to an expanded configuration; retracting the thrombus extraction device proximally so that the coring portion cores and separates a portion of the vascular thrombus from the venous vessel wall while the mesh structure captures the vascular thrombus portion; and withdrawing the thrombus extraction device from the patient to remove the vascular thrombus portion from the vessel.

A hemostatic agent in the form of particles comprises a first component and a second component bound thereto, each component having hemostatic properties. Additional components may also be included. The first component may be a zeolite and the second component may be clay. A device for promoting the clotting of blood comprises a receptacle for retaining particles of a hemostatic agent therein, at least a portion of the receptacle being defined by a mesh. A pad for controlling bleeding comprises a mesh structure defined by openings sized to accommodate the flow of blood therethrough and also by a hemostatic agent retained in the mesh structure. A bandage applicable to a bleeding wound comprises a substrate, a mesh mounted on the substrate, and a hemostatic agent retained in the mesh. The mesh is defined by a plurality of members arranged to define openings through which blood may flow.

The present invention concerns a stent with a highly flexible structure that is configured to provide an elevated degree of vessel scaffolding and to absorb torque applied on the stent. In one embodiment, the stent of the present invention includes an essentially tubular body formed by a web structure that is composed of a plurality of longitudinally adjacent web rings, each including a plurality of web elements that are disposed circumferentially around the longitudinal axis of the stent and that are adjoined one to the other by a junction bend. Each junction bend in a first web ring is coupled to another junction bend in a neighboring ring by a connector having a step-wise configuration, in which a central segment of the connector is disposed essentially parallel to the longitudinal axis of the stent and may become twisted to absorb torque imposed on the stent.

An enhanced, co-formed fibrous web structure is disclosed. The web structure may have a co-formed core layer sandwiched between two scrim layers. The core layer may be formed of a blend of cellulose pulp fibers and melt spun filaments. The scrim layers may be formed of melt spun filaments. Filaments of one or both of the scrim layers, and optionally the core layer, may also be meltblown filaments. The core layer may include consolidated masses of cellulose pulp fibers to, for example, enhance texture and cleaning efficacy of a wet wipe made from the structure. The material forming the consolidated masses may be selected and / or processed so as to cause the masses to have reduced visual discernibility relative the surrounding areas of the structure, when the fibrous web structure is wetted. A method for forming the structure, including formation and inclusion of the consolidated masses, is also disclosed.

A flexible self-expandable stent has inside and outside stent bodies each fabricated by knitting first and second super-elastic shape memory alloy wires into a net-like structure with the first wire zigzagged with a diagonal length P interlocked with the second wire zigzagged with a diagonal length 2P at a plurality of interlocked points with intersecting points therebetween to allow the stent bodies to apply force against longitudinal contraction of the stent bodies. The interlocked points and the intersecting points form a plurality of diamond-shaped meshes in the net-like structure of each stent body. A hollow rubber tube is closely fitted between the inside and outside stent bodies, with each of the overlapped ends of the rubber tube and the stent bodies being integrating into a single structure.

An apparatus for promoting the clotting of blood comprises a substrate and a zeolite in powder form deposited on the substrate. At least a portion of the substrate is selected from a group consisting of paper, polymer matrix, polyethylene sheet, hydrophilic macromolecules, and cloth. An agent for promoting the clotting of blood comprises a porous web structure and a compound capable of providing hemostasis incorporated into the porous web structure. The compound capable of providing hemostasis comprises at least one cationic species interspersed throughout and coulombically bound to the web structure such that the cationic species provides a positive charge to the web structure. A method of fabricating a blood clotting apparatus comprises the steps of providing a cellulose-based substrate; providing a zeolite; incorporating at least one cationic species into a structure of the zeolite to impart a positive charge thereto; and impregnating the cellulose-based substrate with the zeolite.

The invention discloses bio-medical engineering material and preparation method thereof, particularly relates to 3D tissue repair material suitable for adhesively growing of cell and preparation method thereof, belonging to bio-medical material technique domain. The natural tussah silk is used as raw material. After antheraea pernyi silk fibroin dissolves, 3D non-woven web structure composed of antheraea pernyi silk fibroin fibre is obtained by electrostatic spinning, wherein the fibre diameter is 50nm-20 mu m, the hole between the fibres is 1-500 mu m, the thickness of non-woven web is 50nm-20mm, and molecular weight of the antheraea pernyi silk fibroin is 10X10<4>-20X10<5>D. The bio-medical engineering material has features of non-poison, harmless, good biocampatibility, good adhesive growth ability of cell, etc. Because of the wide materials supply and low cost, the said material will replace some high-cost bio-medical material such as collagen, and will be used for repair material such as artificial skin, tendon, cartilage, duramater and so on, particularly for histiocyte induction material.

An apparatus for promoting the clotting of blood and controlling bleeding comprises a receptacle for retaining molecular sieve material in particulate form therein. A pad for controlling bleeding comprises a mesh structure and a rigid or semi-rigid support attached to the mesh structure to facilitate the application of pressure to the pad and the wound. A bandage applicable to a bleeding wound comprises a mesh structure and a flexible substrate attached to the mesh structure, the substrate being a cloth or plastic member that may be adhesively attached to cover a wound. In any embodiment, at least a portion of the receptacle or mesh structure is defined by a mesh having openings therein, and at least a portion of the particulate molecular sieve material is in direct contact with blood.