572 results about "Capillary vessels" patented technology

The invention consists of a sensor with multiple indicating (sensing) electrodes covered with a selectively permeable membrane for monitoring fluid concentrations in a biological environment. The indicating electrodes respond to changes in certain analytes, such as glucose, through an enzyme-mediated reaction. The currents generated from the enzyme-mediated reactions are transmitted through radio signals to an external receiver where the information is processed and recorded. Through the use of various biomaterials and biochemicals associated with the sensor, the monitoring accuracy is improved and the overall viability is prolonged. The process of foreign body fibrosis (formation of a scar capsule around the implanted sensor) eventually limits the functional life of the device. We teach methods of delivery of certain biochemicals that can increase the functional life of the sensor by inhibiting the formation of the foreign body capsule or by stimulating the growth of capillaries into the capsule.

A method for determining tissue type includes quantitatively determining a tissue blood flow (TBF) by deconvoluting Q(t) and Ca(t), where Q(t) represents a curve of specific mass of contrast, and Ca(t) represents an arterial curve of contrast concentration, and quantitatively determining a tissue blood volume (TBV) by deconvoluting Q(t) and Ca(t). The method also includes quantitatively determining a tissue mean transit time (TMTT) by deconvoluting Q(t) and Ca(t), and quantitatively determining a tissue capillary permeability surface area product (TPS) by deconvoluting Q(t) and Ca(t). The method also includes determining a tissue type based on the TBF, the TBV, the TMTT, and the TPS.

A device for assessing capillary vitality comprises an inflatable cuff, a blood flow sensor and a pressure sensor in communication with the cuff, a pressure instrument in fluid communication with the cuff for inflation and deflation thereof, a microprocessor coupled to the pressure instrument for controlling airflow, at least one metabolic sensor for measuring a metabolic condition, and a computer program executable by the microprocessor. The pressure instrument includes a source of pressurized air and a conduit connecting the source of pressurized air to the cuff. The microprocessor is arranged to receive inputs from the blood flow, pressure and metabolic sensors. When executed by the microprocessor, the computer program causes the microprocessor to initiate an automatic inflation sequence resulting in a no flow condition, initiate an automatic deflation sequence, automatically qualify a perfusion measurement as an SPP value upon one or more conditions being met during the deflation sequence, and initiate the measurement of at least one metabolic factor.

A device for measuring the capillary refill time of a patient and for use in determining an amount of oxygen in the blood of the patient has light sources and a light detector for use in carrying out pulse oximetry. The device also includes an actuator for applying pressure to a selected portion of the body of the patient, such as the nail bed of a finger or toe of the patient, to cause the removal of blood from the nail bed when actuated. A timer commences a time interval with a deactuation of the actuator. The deactuation relieves the pressure applied by the actuator to the body portion of the patient and allows blood to return to the portion. The timing interval is terminated by a reduction in the amount of light received by the light detector as a result of the restoration of blood to the body portion. The time interval so determined comprises an indication of the capillary refill time of the patient. Compensation in accordance with a skin temperature measurement may be provided.

A method is disclosed for disrupting capillary blood flow and trapping materials such as chemotherapeutic agents in undesirable tissue, including cells of a cancerous or non-cancerous tumor. The method involves the placement of electrodes into or near the vicinity of capillary vessels supplying blood to capillaries in the undesirable tissue, and application of electrical pulses causing capillary blood flow disruption. In some cases, the electric pulses irreversibly permeate the cell membranes, thereby invoking cell death. The irreversibly permeabilized cells are left in situ and are removed by the body's immune system. The process may further comprise monitoring blood flow and / or infusion of a material such as a chemotherapeutic agent or marker into the blood.

A process for screening an expression library to identify clones expressing enzymes having a desired activity is provided. The process involves first generating from genomic DNA samples of one or more microorganisms an expression library comprising a plurality of recombinant cell clones, and then introducing into capillaries in a capillary array a substrate and at least a subset of the clones, either individually or as a mixture. Interaction of the substrate and a clone expressing an enzyme having the desired activity produces an optically detectable signal, which can then be spatially detected to identify capillaries containing clones producing such a signal. The signal-producing clones can then be recovered from the identified capillaries.

The invention provides an external traditional Chinese medicine preparation for treating chronic wounds, which is prepared from the following raw medicines in parts by weight: 10-20 parts of draconis sanguis, 10-20 parts of chuanxiong rhizome, 10-20 parts of notoginseng, 10-20 parts of fried sanguisorba, 10-20 parts of safflower, 10-20 parts of spatholobus stem, 10-20 parts of giant knotweed, 10-20 parts of oldenlandia, 10-20 parts of red sage root, 10-20 parts of herba patriniae, 10-20 parts of moutan bark, 10-20 parts of myrrh, 10-20 parts of mastic, 10-20 parts of rhubarb, 10-20 parts of natural indigo, 10-20 parts of gromwell, 10-20 parts of catechu, 10-20 parts of borneol, 10-20 parts of phellodendron bark and 10-20 parts of boneset. The external traditional Chinese medicine preparation provided by the invention can promote healing of infectious wounds, increase pus, enhance qualitative viscosity and regenerate granulation to enable the wounds to quickly heal, has an obvious effect on treating wound infection, and can be used for treating partial ulcer, removing necrotic tissue and promoting granulation, accelerating the degeneration process of the necrotic tissue, promoting dilation of capillary vessels, accelerating microcirculation of the capillary vessels and filling the wounds.

A method and system for determination and mapping the quantity of chromophores having a distinct spectrum attached to moving objects in an spectrally rich environment that may include multiple chromophores attached to stationary objects. Au area of interest is imaged at different times and different wavelengths, and the spectral properties of the chromophores attached to the moving objects are separated from the stationary spectral properties of the background, followed by spectral analysis of the moving objects to determine their quantity. Application to the retinal vasculature is illustrated, showing the imaging, analyzing and quantifying of the oxygen saturation of retinal blood, resolved for the different vascular compartments, including capillaries, arterioles, venules, arteries, and veins.

The invention discloses an optical fingerprint identification device with living body scanning function and an optical fingerprint identification method for identifying fingerprint characteristics of a living body and stably and securely performing fingerprint authentication. Two kinds of different colored light with different penetrability are alternately used for assisting in capturing the characteristics of a finger to identify the truth of the finger and capturing fingerprint images of the same finger on different levels to further assist the identification; a red light source can be used for assisting in capturing a surface image of the fingerprints, and a blue-green light source can be used for assisting in capturing a capillary vessel image on the lower layer of the surface of the fingerprints, so that the fingerprints are from the living body or counterfeited silica gel fingerprints can be judged according to the capillary vessel image and the fingerprint surface image; and on the other hand, because more than two images of the same finger can be captured, the comparison characteristics of the same finger can be increased, and the accuracy of identification is increased.