385 results about "4-Nitrophenol" patented technology

The invention belongs to a supported two-dimensional layered molybdenum sulfide composite material and discloses a noble metal (Ag, Au)-supported composite nano-catalytic material and its application in catalytic reduction of p-nitrophenol. The two-step synthetic technology is adopted in the invention. Firstly, molybdenum sulfide nanosheet with a porous ultrathin structure is synthesized by a hydrothermal method; then, by an ultraviolet reduction technology, noble metal nanoparticles are supported onto the surface of the two-dimensional layered compound molybdenum sulfide with a sandwich structure, and agglomeration phenomenon during the noble metal preparation process can be effectively avoided by the combination of nano confinement growth effects; and finally, noble metal nanoparticles with uniform size distribution are obtained. According to the supported catalyst system, the metal catalytic active center and a carrier together form a catalyst due to localized surface plasma resonance effect of noble metal active ingredients and synergistic effect between noble metal active ingredients and the carrier.

The invention relates to a preparing method of an amino carbon quantum dot fluorescence silicon substrate imprint sensor and belongs to the technical field of preparation of an environment function material. The preparing method comprises the following steps: dissolving citric acid and a polymine solution to obtain a transparent solution, then transferring to a hydrothermal reaction kettle for reaction, and then cooling to room temperature to obtain dispersion liquid of amino carbon quantum dots; centrifuging the dispersion liquid to obtain an amino carbon quantum dot solution; then taking the amino carbon quantum dots as fluorescence carriers, p-nitrophenol as template molecules, (3-aminopropyl) triethoxy silane as a function monomer, and tetraethoxysilane as a cross-linking agent so as to obtain a fluorescence molecular imprinted polymer to be used for optical detection of p-nitrophenol. The amino carbon quantum dot fluorescence molecular imprinted polymer has very good optical and pH stabilities and has te capacity of selectively recognizing p-nitrophenol.

Carbon nanotubes (CNTs) are promising nanomaterials that have the potential to revolutionize water and waste treatment practices in the future. The direct use of unbounded CNTs, however, poses health risks to humans and ecosystems because they are difficult to separate from treated water. Here, we report the design and synthesis of carbon nanotube ponytails (CNPs) by integrating CNTs into micrometer-sized particles, which greatly improves the effectiveness of post-treatment separation using gravitational sedimentation, magnetic attraction, and membrane filtration. We further demonstrate that CNPs can effectively perform major treatment tasks, including adsorption, disinfection, and catalysis. Using model contaminants, such as methylene blue, Escherichia coli, and p-nitrophenol, we show that all the surfaces of individual CNTs in CNPs are accessible during water treatment. Hierarchical structures containing CNPs can be employed in a multitude of nano-material engineering applications, such as water and waste treatment.

The invention discloses a gold-MOFs-polymer composite membrane, and a production method and an application thereof, and belongs to the technical field of polymeric functional membranes. An MOFs-polymer composite membrane obtained through self assembling of a covalent bond driven NMOFs material and mercapto group-containing functional polysiloxane is adopted to load gold nano-particles as a matrix in order to obtain the gold-MOFs-polymer composite membrane material. The gold-MOFs-polymer composite membrane has a high catalysis effect on Knoevenagel condensation of 4-nitrobenzaldehyde at room temperature and reduction of 4-nitrophenol as a continuous flow-through membrane reactor. The composite membrane has great application prospect in the field of membrane catalysis.

The invention discloses a new method for detecting p-nitrophenol by using a PDDA functionalized graphene modified glassy carbon electrode. The method comprises the following steps: taking 50mL of 1mg*mL<-1> graphene oxide solution, and performing an ultrasonic treatment for 4 hours; adding 1mL of 20% PDDA solution into 50mL of secondary water, uniformly mixing, then adding the graphene oxide solution into the PDDA solution in a magnetic stirring manner, keeping on stirring for 30 minutes, adding 1.5mL of hydrazine hydrate (80%), uniformly stirring, putting into a hydrothermal synthesis reactor and reacting for 3 hours at 100 degrees centigrade, cooling, centrifuging and washing by using the secondary water, and performing vacuum drying at 60 degrees centigrade to obtain the PDDA functionalized graphene. Not only is the dispersibility of the PDDA functionalized graphene in the water increased, but also the graphene has positive electricity, a good matrix is provided for preparation of a graphene-based composite material, and the application of the graphene in electro-analytical chemistry is widened.

Belonging to the technical field of catalysis, the invention relates to an Au / Co(OH)2 nano-array structured catalyst. A rectangular flaky nano-array directly grows on a foamed nickel substrate, and the formed nano-material has a determined and ordered structure, and can realize a high specific surface area. The micron pieces on the foamed nickel substrate are connected with the macroscopic scale substrate and of nanoscale noble metal particles, thus ensuring enough adhesion and avoiding leaching in catalytic reaction. The average size of a single square nano-sheet is 1.5-micrometer wide, and the size of gold particles is 3-5nm. The catalyst can be effectively used for hydrogenation reduction reaction of p-nitrophenol, and the reaction rate is 30.8s<-1>g<-1>. The Au / Co(OH)2 nano-array structured catalyst also has excellent cycling stability, basically has no appearance change after 6 cycles of use, and more importantly, generally maintains unchanged catalytic performance. The problems of nonuniform active component distribution, weak cohesiveness with the carrier and gradual decrease of activity during reaction in traditional monolithic catalysts are solved.

The invention relates to a novel method for preparing loading type nanometer nickel catalyst; the method takes a carrier loaded with a revulsant as a precursor to induce hydrazine hydrate to reduce a nickel salt solution; the crystal grains of the formed nanometer nickel is directionally deposited on the surface of the carrier with no aggregation; the loading type nanometer nickel catalyst prepared by the method has the advantages of high loading of activating components, small grain diameters, good dispersibility and high activity as well as being suitable for catalytic hydrogenation reaction.

The invention discloses a yolk-eggshell structure Au@ hollow carbon nanosphere composite material and preparation and application thereof. A preparation method includes the following steps that sodium citrate is adopted for reducing chlorogoldacid, and nanogold hydrosol is prepared; the nanogold hydrosol, organic monomers, water and a Triton X-100 aqueous solution are stirred and mixed; then, an initiating agent is added into a system to initiate polymerization of the monomers, and precursors are prepared; the organic monomers are composed of aniline and pyrrole; and under the inert atmosphere, the precursors are processed in a high-temperature carbonizing manner so that the yolk-eggshell structure Au@ hollow carbon nanosphere composite material can be prepared. According to the preparation method, the tedious steps that a template is prepared, complicated surface modification is needed and the template is removed are not needed, and preparation is easy and convenient. The specific surface area and the size of the prepared material can be regulated and controlled through the carbonization condition and the concentration of the organic monomers, the specific surface area is high, and the prepared material has a good catalytic effect on nitrobenzene and p-nitrophenol.

The invention provides a preparation method of a nitrogen-doped mesoporous carbon catalyst for wastewater degradation. The preparation method comprises the following steps: zinc salt and nitrogen-containing ligand at the mole ratio of (1:1) to (5:1) are dissolved in an organic solvent to form a homogeneous solution, 5-20 mL of triethylamine is added into the solution dropwise, the solution is stirred for 0.5-3 h and filtered to obtain a solid product, and the solid product is subjected to washing, solvent exchange and vacuum drying to obtain powder of metal-organic frameworks containing nitrogen and zinc; the powder of metal-organic frameworks containing nitrogen and zinc is heated in a nitrogen atmosphere to be greater than or equal to 910 DEG C at the speed of 2-20 DEG C / min, and the temperature is kept for 1-12 h, and then is reduced to the room temperature, so that the catalyst is obtained. The invention further provides the nitrogen-doped mesoporous carbon catalyst for wastewater degradation, which is prepared by the preparation method, and application of the catalyst to wastewater degradation. The catalyst does not contain metals, has a low nitrogen content and a larger specific surface area, is easy in preparation method and economic in step, and can efficiently degrade 4-nitrophenol in wastewater.

The invention relates to a carbon nitride loaded iron oxide photocatalyst capable of efficiently degrading p-nitrophenol and belongs to the field of nano material preparation. A preparation method of the carbon nitride loaded iron oxide photocatalyst includes: using a thermal polymerization method to prepare a carrier g-C3N4, and grinding the obtained sample into powder for standby; using an equivalent-volume impregnation method to prepare Fe2O3 / g-C3N4, to be more specific, weighing a certain amount of iron nitrate, using isopropanol as the solvent, using the equivalent-volume impregnation method to impregnate the iron nitrate solution into the carrier, transferring the obtained mixture into a tube furnace, heating from room temperature to 350 DEG C at the speed of 1 DEG C / minute, and keeping the temperature for 3 hours to obtain the Fe2O3 / g-C3N4. The Fe2O3 / g-C3N4 catalyst prepared by the method has excellent photocatalytic performance on the p-nitrophenol. The carbon nitride loaded iron oxide photocatalyst is cheap in raw material, easy in raw material obtaining, simple in preparation process, high in yield and promising in application prospect in the photocatalysis field.

The invention discloses a preparation method a ferriferrous oxide-polyaniline-gold nano composite material. According to the preparation method, nano Fe3O4 is synthesized via solvothermal method, and is taken as the core of the composite material; Fe3O4 is uniformly dispersed into a PVP aqueous solution; aniline monomer, citric acid, and initiator ammonium peroxydisulfate are added respectively under ice bath and continuous stirring so as to form polyaniline on the surface of nano Fe3O4 from aniline via polymerization, and obtain a Fe3O4-PANI core-shell structure composite material; assembling of prepared gold nanosol with Fe3O4-PANI is realized via electrostatic attraction; and finally seed-mediated growth is adopted, and gold shell is prepared from gold seed with methanol and a reductive gold salt solution so as to obtain the ferriferrous oxide-polyaniline-gold nano composite material. The preparation method of ferriferrous oxide-polyaniline-gold nano composite material is low in cost, simple in technology, and excellent in performance; and the ferriferrous oxide-polyaniline-gold nano composite material is sensitive and rapid, and can be recycled in catalyzing pollutant p-nitrophenol.

The invention discloses a making method of 4-hydroxy-6-oxy-7-ethoxy-3-quinoline carboxylic acid carbethoxy in the coccidiostat domain, which comprises the following steps: A. preparing catechol diethyl ether; B. making .3, 4-diethyloxy nitrobenzene; C. making 2-ethoxy-4-nitrophenol; D. making 3-ethoxy-4-oxynitrobenzene; E. making 3-ethoxy-4-oxyphenylamine; F. preparing N-methylene ethyl malonate-3-ethoxy-4-oxyphenylamine; G obtaining the product.

The invention relates to a bentonite-loaded sulfurized nanoscale zero-valent iron composite material and a preparation method and application thereof. According to the composite material, sulfurized modified nanoscale zero-valent iron is loaded on bentonite; the mass ratio of bentonite to total iron is (0.85-1.2):1, and the molar ratio of a sulfur element to total iron is (0.05-0.065):1. The bentonite-loaded sulfurized nanoscale zero-valent iron composite material is more stable and efficient, and is suitable for treatment of multiple pollutants; electron transfer on the surface of the nanoscale zero-valent iron can be accelerated through sulfurized modification and corrosion is promoted, thereby greatly improving the reaction activity of the material; furthermore, the sulfuration process is simple and is free of pollution; and the material is not easy to reunite when loaded on bentonite and the activity can be kept for a long period of time. The removal rate of the material on 4-nitrophenol within 2min reaches over 97.5%, and the removal rate on orange I is close to 100%.

The invention discloses a high performance and high strength hydrogel based on gold nano particles. A cationic liquid namely 3-(methacryloylamino) propyl trimethyl ammonium chloride and an anionic liquid namely sodium p-styrene sulfonate are taken as the copolymerization monomers; alpha-keto-glutaric acid is taken as a photoinitiator; in a NaCl solution, polymerization is triggered by UV rays, andthen the reaction product is crosslinked with an amphoteric particle polymer namely 1-vinyl-3-propyl imidazole sulfonate through ion bonds to synthesize the hydrogel with high mechanical strength. The hydrogel adsorbs AuCl4 through ion bonds; and finally, through reduction of sodium borohydride, gold nano particles are fixed in the gel to form P(PVIS) / P(NaSS-MPTC) / Au composite gel. The compositegel has a high catalytic activity on 4-nitrophenol reduction reactions under the action of a NaBH4 solution, and the reactions finish within 20 minutes.

The invention belongs to the technical field of nano-materials, and relates to a preparation method of recyclable supported nano-silver catalyst materials and an application of the materials, in particular to a silver nano-catalyst preparation method based on surface-functionalization cellulose paper base and application of the preparation method to circular catalysis and transformation of environmental pollutants. The preparation method of the recyclable cellulose paper base nano-silver catalyst materials includes the steps: taking cellulose paper base materials as a support; performing amino modification on support surfaces by the aid of silane coupling agents; enabling amino of the modified support surfaces and metal precursor ions to chelate; adding reducing agents to reduce to form the cellulose paper base nano-silver catalyst materials. The prepared cellulose paper base nano-silver catalyst materials serve as a catalyst to reduce 4-aminophenol by the aid of 4-nitrophenol, are high in catalytic activity and good in reusable performance and still keep higher catalytic activity when continually and circularly being used by 20 times or more, support stability and silver nano-stability are high, and catalysts are easily recycled.

The invention relates to a fluorine-containing diamine monomer with an asymmetric aromatic ether structure, a synthetic method thereof and fluorine-containing polyimide prepared from the diamine monomer. The diamine monomer has a structural formula as described in the specification; polyimide has a structural formula as described in the specification, and n in the structural formula of polyimide is in a range of 100 to 500. The synthetic method is as follows: 2-fluoro-4-nitrophenol and 4-nitrochlorobenzene undergo nucleophilic substitution so as to prepare FNNB; the diamine monomer is prepared from FNNB with Pd / C as a catalyst and hydrazine hydrate as a reducing agent; and the diamine monomer and 6FDA undergo polycondensation so as to prepare polyimide. According to the invention, ether groups and fluorine-containing strong hydrophobic groups are introduced into the diamine monomer, so the diamine monomer has weak polarity, thereby enabling the polarity of polyimide prepared from the diamine monomer to be reduced; thus, crystallinity and rigidity of polyimide are reduced, and solubility and the water absorption rate of polyimide are improved. Since polyimide has an aromatic structure, good mechanical properties and thermal stability are provided, which is favorable for development of a humidity sensing device.

The invention provides a method for preparing a cobalt-nickel double metal hydroxide nano composite through a hydrolytic process, belonging to the technical field of nano material preparation. The method is carried out under the condition of room temperature, dispenses with heating and temperature control devices and takes distilled water as a solvent, hydrolysis of sodium borohydride is utilized to provide an alkaline environment for reaction, the synthetic steps are simple, the yield is high and the obtained cobalt-nickel double metal hydroxide nano composite is a grapheme-like structure. The method is simple and energy-saving in preparation process and is suitable for industrial production. The obtained cobalt-nickel double metal hydroxide nano composite has good catalytic effects on hydrogenation of p-nitrophenol.

The invention relates to a preparation method and application of multiple magnetic mesoporous catalysts, and belongs to the technical fields of material science, nanometer materials, chemical industries, catalysis and the like. The method disclosed by the invention comprises the following steps: performing ultrasonic treatment for Fe3O4 microspheres of which the surfaces are carboxylated, zinc nitrate, cyanuric chloride tribasic carboxylic acids H3L and ethyl orthosilicate in one step to obtain Fe3O4@-MOF@SiO2, dipping the composite materials in a silver nitrate solution, and illuminating the composite materials with ultraviolet rays to reduce Ag<+> to obtain the multiple magnetic mesoporous catalysts, wherein nanometer Ag is anchored on the surfaces of the catalysts. The catalysts have excellent properties of catalyzing and reducing 4-nitrophenol to 4-aminophenol and catalyzing styrene to be oxidized as phenyl ethylene oxide, and the catalysts have a favorable application prospect in heterogeneous catalysis oxidation and reduction reactions.

The invention discloses a preparation method for a catalyst efficiently catalyzing hydrogenation reduction of 4-nitrophenol, and belongs to the technical field of nanometer material preparation and application. Employed graphene-shaped non-integer-ratio cobaltous selenide (Co[0.85]Se) has the thickness not larger than 10 nanometer, and titanium dioxide supported by the cobaltous selenide (Co[0.85]Se) has the particle size of about 10 nanometer. The catalyst is large in specific surface area, has high catalytic efficiency on hydrogenation reduction of 4-nitrophenol, does not employ noble metals and is low in cost. The preparation method is simple, easy to operate, free of organic templates and surfactants, and suitable for industrial production. The prepared titanium dioxide / cobaltous selenide (Co[0.85]Se) is pure in phase, large in specific surface area, good in catalytic reduction effect on 4-nitrophenol and high in repeated utilization value, and has potential utilization value on the aspect of sewage processing.

The invention belongs to the technical field of water treatment and particularly relates to a Fe3O4 / CeO2 nanometer composite material, a preparation method and application. The composite material is prepared through a coprecipitation method. The surface of CeO2 is wrapped by nanometer Fe3O4 particles in the composite material. The Fe3O4 / CeO2 nanometer composite material can serve as peroxide mimic enzyme to be applied to treating p-nitrophenol waste water. The invention provides the preparation method of the new Fe3O4 / CeO2 nanometer composite material. The preparation method is high in operability and can well meet requirements of large-scale production and actual application. With the Fe3O4 / CeO2 nanometer composite material prepared through the new method as a base, the inventor performs new application research, when the Fe3O4 / CeO2 nanometer composite material is applied to treating p-nitrophenol wastewater, a good application effect is shown, the p-nitrophenol degrading rate can be well kept at 90% or above, and application prospects are good.

The invention relates to a preparation method of amino carbon quantum dots for detecting 4-nitrophenol and belongs to the technical field of preparation of novel nano-materials. The preparation method comprises the following steps: citric acid and polyethyleneimine in certain mass are dissolved in water firstly, and a transparent solution is obtained; then the solution is transferred into a hydrothermal reaction kettle, the hydrothermal reaction kettle is placed in an oven for reaction, and a dispersion liquid of the amino carbon quantum dots is obtained through cooling; the dispersion liquid is centrifuged, a supernatant is injected into a dialysis bag for dialysis, dialysis is performed for multiple times, and the amino carbon quantum dots are obtained through drying. The amino carbon quantum dots prepared with the method have very good stability and optical properties as well as 4-nitrophenol recognition capacity; the preparation method adopts simple equipment, is simple, convenient and feasible to operate, high in yield, high in conversion rate and fluorescence yield and good in repeatability, and adopted materials are environment-friendly and pollution-free.

The invention relates to a method for synthesis of dronedarone. The method comprises the following steps that 1), p-nitrophenol, paraformaldehyde and concentrated hydrochloric acid as raw materials undergo a condensation reaction in the presence of concentrated hydrochloric acid or phosphoric acid as a catalyst to produce 2-chloromethyl-4-nitrophenol; 2), 2-chloromethyl-4-nitrophenol and triphenylphosphine undergo a reflux reaction in the presence of chloroform to produce 2-hydroxy-5-nitrobenzyl-triphenyl-phosphonium chloride, and 3), 2-hydroxy-5-nitrobenzyl-triphenyl-phosphonium chloride and n-valeryl chloride undergo a condensation reaction in a toluene solution in the presence of triethylamine and n-pentanoic acid as catalysts to produce 2-(n-butyl)-5-nitrobenzofuran.

The invention discloses a deep-sea sediment-sourced novel esterase EST4 as well as an encoding gene and application thereof. A deep-sea sediment-sourced esterase gene est4 is obtained by screening a metagenome and has a nucleotide sequence shown as SEQ ID NO. 1, and the esterase EST4 encoded thereby has an amino acid sequence shown as SEQ ID NO. 2. After heterologous expression of the esterase gene provided by the invention, the catalytic activity is highest when a substrate is p-nitrophenol caproate (C6) and the enzymatic activity is 56.1U / mg. The optimum temperature for catalytic hydrolysis of the esterase EST4 is 35-40 DEG C; in the presence of Ca<2+>, Co<2+>, Sr<2+> and Zn<2+>, the enzymatic activity is increased. The esterase can be applied to chiral medicine synthesis, food processing and food flavor modification, wastewater treatment and washing industry and other industrial productions.

A disclosed fertilizer quick-acting long-acting synergist comprises the following raw materials: 2, 4-dinitrophenol sodium salt, 4-nitrophenol sodium salt, 2-nitrophenol sodium salt, polyaspartic acid, polyglutamic acid, hydroquinone, thiourea, 3,4-dimethyl-1H-pyrazolium dihydrogen phosphate, acrylamide, dicyandiamide, N-J N-(N-butyl)thiophosphoric triamide, 2-methoxy-5-nitrophenol, sodium alpha-naphthyl acetate, 6-benzylaminopurine, humic acid and potassium hydroxide. The fertilizer quick-acting long-acting synergist is substantially improved in selection and proportion of the raw materials; by cooperating with a fertilizer, the synergist is capable of making the fertilizer rapidly work, keeping long-term effectiveness of the fertilizer, prolonging the fertilizer effectiveness up to 140 days mostly, comprehensively improving fertilizer effective availability by 30% or more and saving fertilizer usage amount by 20%, wherein crops applied with the synergist have substantial effect on absorption and growth just after 1-2 days.

The invention relates to a preparation method of a molybdenum disulfide coated titanium dioxide hollow core-shell structure composite photocatalyst, and application of the photocatalyst. The problems that the composite photocatalyst synthesized by the existing method is expensive and has bad 4-nitrophenol treatment effect are solved. According to the method, MoS2 grows on the surface of hollow TiO2 in situ by a hydrothermal method, the specific surface of the composite photocatalyst is increased, and the interfacial charge transfer rate is increased; furthermore, the preparation method has the advantages of simple, green and efficient synthesis method. The molybdenum disulfide coated titanium dioxide hollow core-shell structure composite photocatalyst is used for performing photocatalytic reduction on 4-nitrophenol into 4-aminophenol.

The present invention provides a hydrazone bond-containing block copolymer having targeting antitumor activity. The preparation method comprises that: 4-nitrophenol methacrylate is subjected to RAFT polymerization to form a hydrophobic block, a good-biocompatibility hydrophilic polymer N-(2-hydroxypropyl)methacrylamide is introduced as a hydrophilic block, a double bond-containing folic acid targeting monomer is subjected to initiation polymerization to obtain a block polymer, and finally hydrazinolysis and a series of modification reactions are performed to introduce a pH sensitive group hydrazone bond. According to the present invention, with the doxorubicin-supporting block copolymer drug micelles, the toxicity of the small molecule drug in the body is reduced, and the residence time of the anticancer drug in the tumor cells is substantially prolonged; and the tumor cell growth inhibition experiment results prove that the copolymer provides a strong inhibition effect on HELA cells, the acidic pH-sensitive smart release bond (hydrazone bond) can identify the tumor cell micro-acidic environment, and the drug can break after reaching the tumor site so as to achieve the targeting antitumor activity of the drug, such that the copolymer is the antitumor activity substance having application prospects.

The invention presents a transfer glycation alpha-D-galactosides enzyme gene, this gene is gained with the PCR amplified of Bifidobacteriumbreve gene group DNA to get the high conservative DNA fragments and crossbreeds with Southern. The full length of its nucleotide sequence is 2226 base, and codes 741 amino acids. The attribute of the recombination enzyme ,which is expressed by this gene, is that the enzyme is double-subunit albumen, the molecular weight of polymer is about 160kD, the molecular weight of sigle-subunit is about 80kD, the Km of this enzyme to nitrophenol alpha-D-galactosides is 0.17mmol / L, Vmax is 4.43 mol / (Líñmin); the best reaction temperature is 37 deg.C, and the best PH is 5.5-6.0, the enzyme has transfer glycation activity in the reaction system of hydrolysis melibinose, or raffinose, this reaction can create transfer glycation production; the different of the enzymeí»s glycosides substrate can be used to compound many glycoconjugate of a-galactosides oligosaccharide and alpha-D-galactosides. The gains of the enzyme can be used to get alpha-galactosides compound enyzme by gene alteration, and improve the compound efficiency of alpha-galactosides oligosaccharide with glycoconjugate radically.

The invention relates to a nanometer noble metal / POSS hybridized polymer micro sphere and a preparation method thereof. A POSS-end-capped amphiphilic polymer can be assembled into an aggregate type reverse micelle in a nonpolar solvent. The nanometer noble metal is prepared by using a water pool made of the reverse micelle as a reactor, and reverse micelle crosslinking is carried out finally to obtain stable hybridized polymer micro sphere containing nanometer noble metal. The invention provides a simple and easy method for preparing the nanometer noble metal / POSS hybridized polymer micro sphere by steps of carrying out assembling and encapsulating in sequence. The content and size of the noble metal can be realized by controlling the size of the water pool. A catalytic reduction test on the p-nitrophenol shows that the hybridized micro sphere has efficient catalytic performance. The nanometer noble metal / POSS hybridized polymer micro sphere and the preparation method thereof are expected to be applied to the fields of selectivity catalysis and biological medicine.

The invention discloses a preparation method of 2-amino-4-nitrophenol. The method consists of the steps of: (1) in a solvent and in the presence of alkali, subjecting 2, 4-dinitrochlorobenzene to hydrolysis reaction, and then carrying out acidification reaction with acid to obtain 2, 4-dinitrophenol; and (2) in the presence of a catalyst, subjecting the 2, 4-dinitrophenol obtained in step (1) and hydrazine hydrate to reduction reaction so as to obtain the 2-amino-4-nitrophenol, with the catalyst being a combination of ferric trichloride hexahydrate and activated carbon. The preparation method of the invention has the advantages of milder reaction conditions, no byproduct, economical efficiency and environmental protection, simple post-treatment, and high reaction yield, and is suitable for industrial production. (reaction formulas).

The invention discloses a preparation method of arbidol hydrochloride. The preparation method comprises the following steps of: (1) performing hydroxylation reaction on 3-iodo-4-nitrophenol serving as a raw material by using acetyl chloride to obtain a compound I; (2) performing substitution reaction on the compound I and ethyl acetoacetate under the action of alkali to obtain a compound II; (3) performing reduction-condensation concerted reaction on the compound II under the conditions of acetic acid and iron powder to synthesize an indole ring, and obtaining a compound III; (4) performing N-methylation reaction on the compound III by using dimethyl sulfate to obtain a compound IV; (5) performing di-bromination reaction on the compound IV in carbon tetrachloride by using bromine to obtain a compound V; (6) reacting the compound V and thiophenol under the alkali condition, and obtaining a compound VI after acidifying; (7) preparing a compound VII from the compound VI in the presence of a reaction solvent, namely aqueous solution of dimethylamine and formaldehyde; and (8) acidifying the compound VII in hot acetone to obtain the arbidol hydrochloride. The preparation method is facile in raw materials, mild in reaction conditions, high in yield, easy in separation and purification, low in cost and suitable for industrialized production.