36results about How to "The composition of the prescription is simple" patented technology

The invention relates to a medical composition which can tolerate strict high-temperature sterilization. After the medical composition is placed for a long term, each quality index does not obviously change, thus the medical composition has good stability, is convenient to realize production and has low cost.

The invention discloses an amoxicillin pharmaceutical preparation and a preparation method thereof. The amoxicillin pharmaceutical preparation comprises the following components in parts by mass: 90.0-99.9 parts of amoxicillin and 0.1-10.0 parts of magnesium stearate. The preparation method is a dry-press process. By controlling the particle size distribution of amoxicillin, the particle size distribution of magnesium stearate and the pressure of the dry press, excellent dissolution quantity and stability of the amoxicillin preparation can be ensured.

The present invention provides a sodium rabeprazole composition for injection. The composition comprises sodium rabeprazole and disodium edetate, wherein a weight ratio of the sodium rabeprazole to the disodium edentate is 1:0.15-1. The sodium rabeprazole composition does not contain mannitol and other fillers. According to the sodium rabeprazole composition, under a certain premise, freeze drying rate of the product is significantly improved so as to avoid additional sublimation time, such that production efficiency is improved, and production energy consumption is reduced, wherein the premise comprises that a product appearance is ensured and reconstituting property meets injection requirements. In addition, the method is suitable for industrial mass production.

The invention relates to a capsule containing mosapride citrate and a preparation method thereof. The capsule includes drug granules and a capsule casing. The drug granules contain the mosapride citrate and / or a mosapride citrate dihydrate, a diluent, a binder, a disintegrating agent and a lubricant. The mosapride citrate in the capsule can be quickly dissolved out at high dissolution rate, so that bioavailability is increased. The formula and the preparation method are simple, have high controllability and low production cost, and are easy to achieve in industrial production.

The present invention discloses a polypeptide drug-containing self-nano-emulsion oral preparation and a preparation method thereof. According to the present invention, a polypeptide drug is added to an auxiliary surfactant, stirring is performed until the polypeptide medicine is wet to obtain a solution A, the solution A is added to an oil phase solution to dissolve and uniformly mix to obtain a solution B, a surfactant is added to the solution B, uniform mixing is performed to obtain a polypeptide drug-containing self-nano-emulsion, and the polypeptide drug-containing self-nano-emulsion is encapsulated in an enteric soft capsule from the nanoemulsion to obtain the polypeptide drug-containing self-nano-emulsion oral preparation. According to the present invention, the preparation method is simple, the obtained nanometer micro-emulsion has characteristics of small particle size, easy absorption, high bioavailability and good stability, wherein the particle size of 99.3% of the emulsion droplets is less than 44 nm, the Zeta potential is -6.4 mv, and the nano Milk with better stability.

The invention belongs to the field of medicines and provides an orally disintegrating tablet containing faropenem sodium. The orally disintegrating tablet also contains mannitol and a lubricating agent. According to the orally disintegrating tablet, less auxiliary materials are used; the composition formula is simple; the orally disintegrating tablet which is prepared from powder through tabletting still has good fluidity; the obtained tablet is reliable in hardness and high in disintegrating speed; and the dissolution behavior of the main drug is excellent.

The invention belongs to the technical field of medicine, and relates to an oral instant film preparation containing rizatriptan benzoate prepared by an electrospinning process. The oral instant film prescription comprises 1 part of rizatriptan benzoate, 1-300 parts of film-forming material and 0-50 parts of other auxiliary materials. Oral instant film is obtained through electrospinning process. The conditions of electrospinning are: voltage 5-20kV, advancing speed 0.1-10ml / h, receiving distance 5-20cm, temperature 5-60℃, humidity 10-70%. The oral instant film is composed of nano-polymer fibers formed by electrospinning, and the diameter of the nano-polymer fibers is 10-1000nm. The rizatriptan benzoate is uniformly distributed in an amorphous state in the film preparation. The oral instant film containing rizatriptan benzoate protected by the present invention has higher specific surface area and porosity and faster dissolution rate, more rapid onset, higher bioavailability, and can quickly relieve migraine patient suffering.

The invention relates to a modern traditional Chinese medicine preparation for treating periodontitis and a preparation method of the modern traditional Chinese medicine preparation and belongs to the field of traditional Chinese medicines. The modern traditional Chinese medicine preparation is prepared from raw materials in parts by weight as follows: 9-15 parts of figwort roots, 9-30 parts of rehmannia roots, 6-20 parts of moutan bark and 6-18 parts of mint. The modern traditional Chinese medicine preparation is prepared from the figwort roots, the rehmannia roots, the moutan bark and the mint, attaches great importance to overall dialectic treatment, uses the organic relation between local parts and the whole body, has the efficacy of clearing stomach heat, promoting the secretion of saliva or body fluids and relieving pains, is used for treating periodontitis clinically for many years, has a definite curative effect and a simple formula, is convenient to take and carry for patients after being prepared in the form of capsules and has remarkable anti-inflammable, pain-relieving and antibacterial functions.

The invention relates to a medicinal composition. The composition has high stability, is resistant to strict high-temperature sterilization, and has high light stability. An additive is reduced greatly in comparison to the conventional product of the same type, production is convenient to realize, and cost is reduced.

The invention relates to a medical composition which can tolerate strict high-temperature sterilization. After the medical composition is placed for a long term, each quality index does not obviously change, thus the medical composition has good stability, is convenient to realize production and has low cost.