Heart boosting pulse restoring tablet and its preparation method

A heart-beneficial and diluent technology, applied in pharmaceutical formulations, cardiovascular system diseases, medical preparations containing active ingredients, etc. Reduced effects, simple formulation composition, and simple production method

Inactive Publication Date: 2006-08-30
BEIJING SHENKELIANHUA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] This preparation obviously has the disadvantages of using a lot of excipients and taking a large amount, which is not conducive to taking.
[0004] Chinese patent application publications CN1068041A, CN1101555A, CN1686465A, etc. disclose Yixinfu pulse preparation and its preparation method, but there are also defects such as large amount of auxiliary materials and many sugar-containing auxiliary materials in the preparation.
[0005] At the same time, Yixin Fumai preparations currently have a single dosage form, which is not conducive to the needs of clinical application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] prescription

[0025] Sun-dried Ginseng 150g, Ophiopogon japonicus 150g, Schisandra 100g, Astragalus 150g, Salvia miltiorrhiza 200g, Ligusticum chuanxiong 100g

[0026] Preparation method: Weigh the six flavors of raw medicinal materials such as raw sun-dried ginseng according to the formula, add water to decoct twice, add 10 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second time, decoct for 1 hours, combined the decoction, let it stand for 12 hours, absorbed the supernatant, concentrated into a thick paste, took it out, dried at 70°C, crushed, added an appropriate amount of microcrystalline cellulose, mixed well, granulated with 95% ethanol, and granulated at 60°C Dry, granulate, add an appropriate amount of magnesium stearate, mix well, press into 200 tablets, and coat with film.

Embodiment 2

[0028] prescription

[0029] Sun-dried Ginseng 150g, Ophiopogon japonicus 150g, Schisandra 100g, Astragalus 150g, Salvia miltiorrhiza 200g, Ligusticum chuanxiong 100g

[0030] Preparation method: Weigh the six flavors of raw medicinal materials such as raw sun-dried ginseng according to the formula, add water to decoct twice, add 10 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second time, decoct for 1 hours, combined the decoction, let it stand for 12 hours, absorbed the supernatant, concentrated into a thick paste, took it out, dried at 70°C, crushed, added an appropriate amount of microcrystalline cellulose, mixed well, granulated with 95% ethanol, and granulated at 60°C Dry, granulate, add an appropriate amount of magnesium stearate, mix well, press into 160 tablets, and coat with film.

Embodiment 3

[0032] prescription

[0033] Sun-dried Ginseng 150g, Ophiopogon japonicus 150g, Schisandra 100g, Astragalus 150g, Salvia miltiorrhiza 200g, Ligusticum chuanxiong 100g

[0034] Preparation method: Weigh the six flavors of raw medicinal materials such as raw sun-dried ginseng according to the formula, add water to decoct twice, add 10 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second time, decoct for 1 hours, combined the decoction, let it stand for 12 hours, absorbed the supernatant, concentrated to a clear paste with a relative density of 1.05-1.10 (80°C), spray-dried, crushed the dried particles, added an appropriate amount of microcrystalline cellulose, mixed evenly, and used 95 Granulate with % ethanol, dry at 60°C, granulate, add appropriate amount of magnesium stearate, mix well, press into 200 tablets, coat with film, and get ready.

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PUM

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Abstract

A Chinese medicine in the form of tablet for nourishing qi and Yin, promoting blood circulation and pulse, heart blood stagnation, cardialgia, palpitation, etc is prepared from 6 Chinese-medicinal materials including ginseng, astragalus root, red sage root, Chuan-xiong rhizome, etc, lubricant and diluent (microcrystalline cellulose) through extracting in water, removing solvent to obtain powder and other conventional steps.

Description

technical field [0001] The invention relates to the technical field of manufacturing technology of Chinese patent medicine tablets, in particular to a Yixin Fumai tablet and a preparation method thereof. Background technique [0002] The standard WS3-B-3659-98 of the Ministry of Health of the People's Republic of China contains Yixin Fumai Granules: decoct six medicinal materials such as raw sun-dried ginseng, Radix Ophiopogon japonicus, Schisandra chinensis, Astragalus membranaceus, Salvia miltiorrhiza and Chuanxiong, and decoct them twice with water. Add 10 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second time, decoct for 1 hour, combine the decoction, let it stand for 12 hours, absorb the supernatant, and concentrate to a relative density of 1.20-1.30 (80°C) To clear the ointment, add 1% (by weight) stevioside, 1 times the amount of dextrin, and 2 times the amount of lactose in the ointment, mix well, and gra...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61K9/20A61P9/00
Inventor 周文艳盛四龙周小学
Owner BEIJING SHENKELIANHUA TECH
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