The invention discloses a purification method of a
faropenem sodium hydrate, which comprises the following steps: 1) dissolving a
faropenem sodium hydrate crude product in a lower
alcohol solvent at -20-40 DEG C, adding
active carbon for decoloration, filtering, 2) adding water into filtrate, performing decompression concentration and
evaporation at 0-40 DEG C to remove the lower
alcohol solvent, and 3) adding residual into a
ketone insoluble
solvent, stirring, crystallizing and filtering to form the pure
faropenem sodium hydrate, wherein for the faropenem sodium hydrate crude product, the
water content is 1g:(0.5-2mL). According to the method, the faropenem sodium hydrate crude product is dissolved in the lower
alcohol solvent at the low temperature, a little water is added, and the lower alcohol solvent is evaporated off at the low temperature; the whole purification process is performed at the low temperature all the time, so that the
crystallization yield is increased obviously and reaches above 90%; and residual products in a mother solution are fewer, so that the product cost is lowered.