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A kind of modern Chinese medicinal preparation for treating periodontitis and preparation method thereof

A technology of traditional Chinese medicine preparation and periodontitis, applied in the field of traditional Chinese medicine, can solve problems such as abuse, increased incidence of patients, and little effect, and achieve the effect of simple composition of prescription, easy to take and carry, and definite curative effect

Active Publication Date: 2019-12-24
周贺芙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Local surgical treatment will be accepted by patients, especially middle-aged and elderly patients often have systemic diseases, such as hypertension, diabetes, cardiovascular and cerebrovascular diseases, etc. Therefore, there will be many safety hazards in surgical treatment, and it is time-consuming and troublesome. But the effect is little; at the same time, the use of antibiotics brings the risk of drug resistance, adverse reactions and antibiotic misuse
Therefore, the treatment of periodontitis is in a difficult situation. On the one hand, the incidence of patients is gradually increasing, and on the one hand, the limitations of treatment methods

Method used

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  • A kind of modern Chinese medicinal preparation for treating periodontitis and preparation method thereof
  • A kind of modern Chinese medicinal preparation for treating periodontitis and preparation method thereof
  • A kind of modern Chinese medicinal preparation for treating periodontitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Scrophulariaceae 9g, raw land 9g, peony bark 6g, mint 6g;

[0029] (1) Take Scrophulariaceae and Radix Scrophulariae, add 108ml of 50% ethanol to reflux and extract twice, each time for 1 hour, filter, combine the filtrate, recover ethanol, and measure the thick ointment with a relative density of 1.30 when it is concentrated under reduced pressure to 60°C for later use;

[0030] (2) Take peppermint, add 54ml of water, soak for 0.5 hours, extract the volatile oil for 3 hours, collect the volatile oil, dissolve the volatile oil in ethanol, volatile oil: ethanol = 1:5, add it to the saturated aqueous solution of β-cyclodextrin at 30°C, Volatile oil: β-cyclodextrin: water = 1:9:90, stir at 30°C for 1 hour, 400 rpm, refrigerate for 24 hours, filter, dry at 40°C, pass through a 80-mesh sieve, reserve, distilled water Another device is collected, and the dregs are used for standby;

[0031] (3) Take Moutan cortex, add 54ml of water, soak for 1 hour, collect 36ml of distillat...

Embodiment 2

[0034] Scrophulariaceae 12g, raw land 12g, peony bark 12g, mint 12g;

[0035] (1) Take Scrophulariaceae and Radix Scrophulariae, add 168ml of 60% ethanol to reflux and extract twice, each time for 2 hours, filter, combine the filtrate, recover ethanol, and measure the thick ointment with a relative density of 1.31 when concentrated under reduced pressure to 60°C for later use;

[0036] (2) Take mint, add 120ml of water, soak for 1 hour, extract the volatile oil for 4 hours, collect the volatile oil, dissolve the volatile oil in ethanol, volatile oil: ethanol = 1:5, and add it to the β-cyclodextrin saturated aqueous solution at 30°C, Volatile oil: β-cyclodextrin: water = 1:9:90, stir at 30°C for 1.5 hours, 400 rpm, refrigerate for 24 hours, filter, dry at 40°C, pass through 80-mesh sieve, reserve, distilled water Another device is collected, and the dregs are used for standby;

[0037] (3) Take Moutan cortex, add 120ml of water, soak for 1.5 hours, collect 7 times the distilla...

Embodiment 3

[0040] Scrophulariaceae 15g, raw land 30g, peony bark 20g, mint 18g;

[0041] (1) Take Scrophulariaceae and Radix Scrophulariae, add 360ml of 70% ethanol to reflux and extract three times, each time for 3 hours, filter, combine the filtrate, recover ethanol, measure the thick ointment with a relative density of 1.32 when concentrated under reduced pressure to 60°C for later use;

[0042] (2) Take peppermint, add 198ml of water, soak for 1.5 hours, extract the volatile oil for 5 hours, collect the volatile oil, dissolve the volatile oil in ethanol, volatile oil: ethanol = 1:5, add it to the saturated aqueous solution of β-cyclodextrin at 30°C, Volatile oil: β-cyclodextrin: water = 1:9:90, stir at 30°C for 2 hours, 400 rpm, refrigerate for 24 hours, filter, dry at 40°C, pass through a 80-mesh sieve, reserve, distilled water Another device is collected, and the dregs are used for standby;

[0043] (3) Take Moutan cortex, add 220ml of water, soak for 2 hours, collect 160ml of dis...

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Abstract

The invention relates to a modern traditional Chinese medicine preparation for treating periodontitis and a preparation method of the modern traditional Chinese medicine preparation and belongs to the field of traditional Chinese medicines. The modern traditional Chinese medicine preparation is prepared from raw materials in parts by weight as follows: 9-15 parts of figwort roots, 9-30 parts of rehmannia roots, 6-20 parts of moutan bark and 6-18 parts of mint. The modern traditional Chinese medicine preparation is prepared from the figwort roots, the rehmannia roots, the moutan bark and the mint, attaches great importance to overall dialectic treatment, uses the organic relation between local parts and the whole body, has the efficacy of clearing stomach heat, promoting the secretion of saliva or body fluids and relieving pains, is used for treating periodontitis clinically for many years, has a definite curative effect and a simple formula, is convenient to take and carry for patients after being prepared in the form of capsules and has remarkable anti-inflammable, pain-relieving and antibacterial functions.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and is a modern Chinese medicine preparation for treating periodontitis prepared from Chinese herbal medicines. Background technique [0002] Periodontitis is a relatively common and common oral disease in clinical practice. No country, region, race, gender, or age group is immune. The prevalence of periodontal disease increases with age, and the prevalence increases significantly after the age of 35, reaching a peak at the age of 50-60. Modern medicine believes that periodontitis is a chronic inflammatory disease occurring in periodontal tissue, which may be initiated by plaque microorganisms. The traditional Chinese medicine believes that it is due to the accumulation of heat in the stomach, steaming of the stomach fire, the burning of the meridians, fumigation of the gums, or carelessness in cavity hygiene, food clogging, tartar deposition, and putrefaction due to excessive eatin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/808A61K9/48A61P1/02
CPCA61K9/4866A61K36/534A61K36/71A61K36/804A61K36/808A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 周贺芙周继胡
Owner 周贺芙
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