The invention discloses a high-filling master batch composition for food and medicine packaging polyolefin. A carrier resin is a polyolefin resin which comprises a metallocene polyolefin resin. The composition also comprises filler and a functional aid which comprises a dispersing agent, a coupling agent, a lubricating agent and a stabilizing agent, or a mixture of two of the dispersing agent, the coupling agent, the lubricating agent and the stabilizing agent. The metallocene polyolefin resin is introduced and is used as the carrier resin, and the conventional functional aid and the filler are added, so the obtained filling master batch composition is high in whiteness, dispersibility, melt fluidity, and processability, and good in normal-temperature and low-temperature impact resistance performance, and a product meets the contact and control requirements of food and medicines, can be used as the filling master batch special for the packaging plastic of the foods and medicines, and has the function of coloring master batch.