The invention discloses a U-shaped seamless nickel-chromium iron alloy heat transfer tube for a nuclear steam generator. The U-shaped seamless nickel-chromium iron alloy heat transfer tube comprises the chemical ingredients of no less than 58% of Ni, 28-31% of Cr, 8-11% of Fe, 0.01-0.03% of C, no more than 0.5% of Si, no more than 0.5% of Mn, no more than 0.01% of S, no more than 0.015% of P, no more than 0.05% of Cu, no more than 0.016% of Co, no more than 0.5% of Ti, no more than 0.5% of Al, no more than 0.1% of Nb, no more than 0.003% of B, and no more than 0.005% of N. The surface quality and the dimensional accuracy of a straight pipe are ensured by hot-extruded nickel-chromium-iron alloy tube blank via a plurality of cold-rolling deformation, online degreasing, pure-hydrogen protecting continuous bright heat treatment and vacuum heat treatment; and meanwhile, the U-shaped seamless tube for a steam generator, which is overlong, thin in wall, and is in semicircle transition at the elbow part, is manufactured by bending and forming by the principle of forming a circle by three points.