879results about How to "Increase bone density" patented technology

In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density.

A dietary supplement for benefitting human bone health includes a calcium source, a source of vitamin D activity, and an osteoblast stimulant. A preferred calcium source is microcrystalline hydroxyapatite, which also contains protein (mostly collagen), phosphorus, fat, and other minerals. A preferred source of vitamin D activity is cholecalciferol, and a preferred osteoblast stimulant is ipriflavone. In addition to these basic ingredients, the composition can further include various other minerals known to occur in bone, vitamin C, and glucosamine sulfate, all of which exert beneficial effects on growth and maintenance of healthy bone. A method for benefitting human bone health involves administering a daily regimen of the dietary supplement.

In certain aspects, the present invention provides compositions and methods for increasing red blood cell and / or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.

A spinal fixation system that utilizes a composite rod to which polyaxial pedicle screw / tulip assemblies are secured, a screwdriver that permits independent threading of a guide member to the tulip and independent threading of the pedicle screw, together with interengaging conical surfaces that true the screwdriver with the pedicle screw. In preferred embodiments, the screwdriver includes an elongated drive shaft having a handle end for imparting rotation and a pedicle screw engaging end, a cylindrical guide member rotatably mounted about said drive shaft, a knob at one end of said guide member for rotating same and a threaded tulip engaging end at the other end thereof. A grip is preferably sleeved around the cylindrical drive member and is longitudinally movable between proximal and distal positions wherein its distal end uncovers and covers, respectively, the screw engaging unit.

In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density, as well as for the treatment of multiple myeloma.

Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate and zwitterionic phospholipid.

In certain aspects, the present invention provides compositions and methods for increasing red blood cell and / or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.

In certain aspects, the present invention provides methods for dosing a patient with an activin-ActRIIa antagonist and methods for managing patients treated with an activin-ActRIIa anatagonist. In certain aspects, the methods involve measuring one or more hematologic parameters in a patient.

In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density, as well as for the treatment of multiple myeloma. Methods for dosing a patient with an ActRIIb antagonist are also provided.

In certain aspects, the present invention provides compositions and methods for increasing red blood cell and / or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.

A neutralizing epitope is identified within amino acids 40-64 of the mature form of human myostatin. Antibodies that bind this epitope fall within the scope of the invention and may be murine, chimeric, or humanized antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammals.

A method for providing electromagnetic therapy to a patient includes placing the patient in proximity to an electromagnetic therapy apparatus. The electromagnetic therapy apparatus includes an electrical circuit for generating an electrical drive signal, a first transducer coil and a second transducer coil for generating respective electromagnetic fields in response to the drive signal, a first portion with a configuration corresponding generally with a chair seat, and a second portion with a configuration corresponding generally with a chair back. The first transducer coil is disposed within the first portion and the second transducer coil is disposed within the second portion. The method further includes stimulating the patient with a pulsed electromagnetic field from at least the first and second transducer coils. The pulsed electromagnetic field having a number of pulses, each pulse having a pulse period of ten microseconds to twenty microseconds.

The invention discloses a health product for increasing bone density and a preparation method of the health product. Chinese dwarf cherries, Chinese herbal medicine extracts refined by adopting a modern extraction technology and other raw materials having the function of increasing the bone density are scientifically compounded and are scientifically combined omnibearingly to play a synergistic effect, so as to effectively promote the calcium absorption in multiple aspects, repair and reconstruct the cartilago articularis, promote the generation of synovial fluid, promote the synthesis of collagen in cartilago articularis substrates, prevent the further degradation of cartilage, indirectly reduce the osteoclast function, inhibit the re-absorption of bones, increase the content of bone calcium and perfect the biomechanical properties of the bones, so that the product has a good function of increasing the bone density. A microwave drying technology in the preparation method can be used for further improving the integration and biological stability of the health product, and by means of the antioxidant activity of a grape seed extract in the raw materials, the strong adsorption and inclusion functions of modified dietary fibers and the antifungal propertie of the Chinese herbal medicine extracts, an efficient, safe, nutritional and stable health product having the function of increasing the bone density is prepared finally.

The invention provides a spinal fusion implant, comprising: a cylindrical body with an expandable front end; a cap-shaped extrusion part, which expands the front end of the main body by bearing tension; Can be used as a guide for the engagement of fasteners; fasteners, which engage in closures and push against extrusions. In the present invention, the main body can be inserted into the fusion part during operation, and the front end of the main body can be expanded with extrusions and fasteners, so that the spinal fusion graft can be fixed to fit the anterior and posterior spaces between adjacent vertebrae.

In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density, as well as for the treatment of multiple myeloma.

The present invention relates to a method for increasing bone growth in teeth and / or other craniofacial regions of a subject. This method includes administering to the jaw and / or teeth of the subject a mechanical vibration having a frequency of 10 to 1000 Hz with an acceleration peak of 0.1 to 2.00 g and that can produce a low magnitude strain of 1 to 50 microstrain in the jaw and / or teeth. The present invention also relates to devices that deliver high frequency, low magnitude force to the teeth.

A method of soft tissue treatment of a patient includes placing an applicator onto a surface of the soft tissue, with the applicator including an electrode and a dielectric material vacuum cup. The soft tissue is heated via the electrode. Vacuum is applied to the vacuum cup. The electrode may be at least partially covered by a dielectric material of variable thickness.

A method of increasing bone mass throughout the body of a user. The method may include the steps of obtaining a distributor comprising a plurality of electromagnetic coils, obtaining a controller comprising a processor and a memory device, operably connected to one another, the memory device storing code executable by the processor, selecting a source of electrical current, connecting the source to the controller, and positioning a user proximate the distributor. The method may further include controlling, by the controller in accordance with the code, delivery of electrical current sequentially and exclusively to each coil of the plurality of electromagnetic coils to generate a magnetic field extending into the user.

In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density, as well as for the treatment of multiple myeloma.

A method of soft tissue treatment of a patient comprises placing an applicator onto a surface of a soft tissue, with the applicator including an RF electrode and a dielectric material having a vacuum cup and a dielectric material under the RF electrode, with the dielectric material under the electrode having an absolute value of difference between polarization factor below center of the RF electrode and below edges of the RF electrode in a range from to 0.10005 mm to 19 800 mm, and heating the soft tissue via the RF electrode, and applying vacuum into a cavity under the applicator with changing pressure value inside the cavity under the applicator compared to pressure in the room during the treatment in range from 0.01 kPa to 100 kPa.

A method including administering a beverage composition suitable for human consumption including effective amounts of the following solubilized components, a calcium compound, an organic acid in an amount up to the equivalent amount of a calcium of the calcium compound, an isoflavone, and inulin wherein the effective amounts are sufficient to reduce the risk of bone density loss and are solubilized by a stabilizing agent including one or more of maltol, carrageenan and maltodextrin, and xanthan gum.

A breeding-pig compound premix comprises 0.6-1% of vitamin additive, 3.8-6.3% of trace mineral additive, 4-6% of amino acid additive, 0.5-0.8% of functional additive, 10-12% of flavor, 0.1-0.3% of antioxidant, 2.5-4% of choline chloride, 30-40% of dicalcium phosphate, 30-40% of limestone powder, as well as 2-10% of feed carrier. The adding amount of the premix accounts for 4%; the premix is coupled with the common grain crops, such as corn and soybean meal, and uniformly mixed into full-price formula feed for barren sows, so that the barren sows can timely get rutted and mated to discharge more eggs and produce more litter; therefore, the premix improves the breeding performance of the sows and enhance the economic benefits of the hogpen.

The present invention provides a method of promoting local bone growth by administering a therapeutic amount of a Sost antagonist to a mammalian patient in need thereof. Preferably, the Sost antagonist is an antibody or FAB fragment selectively recognizing any one of SEQ ID NOS: 1-23. The Sost antagonist may be coadministered together or sequentially with a matrix conducive to anchoring new bone growth. Orthopedic and Periodontal devices comprising an implantable portion adapted to be permanently implanted within a mammalian body and bearing an external coating of a Sost antagonist are also disclosed, as it a method of increasing bone density by administering to a mammalian patient a therapeutic amount of a Sost antagonist together with an antiresorptive drug.

The present invention provides a method of promoting local bone growth by administering a therapeutic amount of a Sost antagonist to a mammalian patient in need thereof. Preferably, the Sost antagonist is an antibody or FAB fragment selectively recognizing any one of SEQ ID NOS: 1-23. The Sost antagonist may be coadministered together or sequentially with a matrix conducive to anchoring new bone growth. Orthopedic and Periodontal devices comprising an implantable portion adapted to be permanently implanted within a mammalian body and bearing an external coating of a Sost antagonist are also disclosed, as it a method of increasing bone density by administering to a mammalian patient a therapeutic amount of a Sost antagonist together with an antiresorptive drug.

A method of local treatment of specific bone defects such as osteoporosis or bone cysts comprises the step of local administration of a formulation comprising a fusion peptide containing a first domain comprising PTH or BMP 2 or BMP 7, and a second domain comprising a covalently crosslinkable substrate domain; and a material suitable of forming a biodegradable matrix suitable for cellular growth or in-growth, wherein the fusion peptide is covalently linked to the matrix. In one embodiment, the matrix contains one or more contrast agents, and is preferably formed in the absence of a growth factor. The matrix may be used in the treatment of fluid-filled cysts such as Tarlov cysts, ovarian cysts, arachnoid cysts, aneurysmal bone cysts or hepatic cysts.