88 results about "Craniofacial" patented technology

An integrated system is described in which digital image data of a patient, obtained from a variety of image sources, including CT scanner, X-Ray, 2D or 3D scanners and color photographs, are combined into a common coordinate system to create a virtual three-dimensional patient model. Software tools are provided for manipulating the virtual patient model to simulation changes in position or orientation of craniofacial structures (e.g., jaw or teeth) and simulate their affect on the appearance of the patient. The simulation (which may be pure simulations or may be so-called “morphing” type simulations) enables a comprehensive approach to planning treatment for the patient. In one embodiment, the treatment may encompass orthodontic treatment. Similarly, surgical treatment plans can be created. Data is extracted from the virtual patient model or simulations thereof for purposes of manufacture of customized therapeutic devices for any component of the craniofacial structures, e.g., orthodontic appliances.

A composite surgical implant that is made of a planar sheet of a thermoplastic resin that includes a top surface, a bottom surface, and a surgical grade metal mesh or metal plates contained therein. The implant may be bent by hand, wherein upon the displacement of the implant, the implant will generally maintain the shape to which it has been displaced.

The invention relates to planning orthodontic treatment for a patient, including surgery, using biological constrains such as those arising from bone, soft tissue, and roots of patient's teeth. The invention disclosed herein provides capability to vary the movement ratio between the teeth and bone and soft tissue through treatment simulation to assess the risk factor associated with a particular treatment plan. The invention further provides capability to monitor results of the treatment to determine the actual movement ratio between the teeth and bone and soft tissue and update the database. Additionally, a method and apparatus are disclosed enabling an orthodontist or a user to create an unified three dimensional virtual craniofacial and dentition model of actual, as-is static and functional anatomy of a patient, from data representing facial bone structure; upper jaw and lower jaw; facial soft tissue; teeth including crowns and roots; information of the position of the roots relative to each other; and relative to the facial bone structure of the patient; obtained by scanning as-is anatomy of craniofacial and dentition structures of the patient with a volume scanning device; and data representing three dimensional virtual models of the patient's upper and lower gingiva, obtained from scanning the patient's upper and lower gingiva either (a) with a volume scanning device, or (a) with a surface scanning device. Such craniofacial and dentition models of the patient can be used in optimally planning treatment of a patient.

An external distraction apparatus for performing a craniofacial distraction is disclosed. The external distraction apparatus may comprise a stationary member. The stationary member may be configured to be affixed to a head of a patient. The external distraction apparatus may also comprise laterally disposed distractors. The laterally disposed distractors may extend inferiorly from the stationary member and be moveable relative to the stationary member. The external distraction apparatus may comprise a motor and controller. The motor may be powered with the controller to perform a craniofacial distraction in an automated fashion.

A composite surgical implant that is made of a planar sheet of a thermoplastic resin that includes a top surface (400), a bottom surface (410), and a surgical grade metal mesh (405) contained therein. The implant may be bent by hand, wherein upon the displacement of the implant, the implant will generally maintain the shape to which it has been displaced.

An external distraction apparatus for performing a craniofacial distraction is disclosed. The external distraction apparatus may comprise a stationary member. The stationary member may be configured to be affixed to a head of a patient. The external distraction apparatus may also comprise laterally disposed distractors. The laterally disposed distractors may extend inferiorly from the stationary member and be moveable relative to the stationary member. The external distraction apparatus may comprise a motor and controller. The motor may be powered with the controller to perform a craniofacial distraction in an automated fashion.

An integrated system is described in which digital image data of a patient, obtained from a variety of image sources, including CT scanner, X-Ray, 2D or 3D scanners and color photographs, are combined into a common coordinate system to create a virtual three-dimensional patient model. Software tools are provided for manipulating the virtual patient model to simulation changes in position or orientation of craniofacial structures (e.g., jaw or teeth) and simulate their affect on the appearance of the patient. The simulation (which may be pure simulations or may be so-called “morphing” type simulations) enables a comprehensive approach to planning treatment for the patient. In one embodiment, the treatment may encompass orthodontic treatment. Similarly, surgical treatment plans can be created. Data is extracted from the virtual patient model or simulations thereof for purposes of manufacture of customized therapeutic devices for any component of the craniofacial structures, e.g., orthodontic appliances.

An external distraction apparatus for performing a craniofacial distraction is disclosed. The external distraction apparatus may comprise a stationary member. The stationary member may be configured to be affixed to a head of a patient. The external distraction apparatus may also comprise laterally disposed distractors. The laterally disposed distractors may extend inferiorly from the stationary member and be moveable relative to the stationary member. The external distraction apparatus may comprise a motor and controller. The motor may be powered with the controller to perform a craniofacial distraction in an automated fashion.

A composite surgical implant that is made of a planar sheet of a thermoplastic resin that includes a top surface (400), a bottom surface (410), and a surgical grade metal mesh (405) contained therein. The implant may be bent by hand, wherein upon the displacement of the implant, the implant will generally maintain the shape to which it has been displaced.

The invention discloses an automatic tooth arrangement method and an automatic tooth arrangement device, relating to the medical field of digital orthodontics, and solving the problem that the automatic tooth arrangement is poor in accuracy. The main technical scheme is as follows: the automatic tooth arrangement method comprises the following steps: acquiring three-dimensional data of dentition needing orthodontics and three-dimensional data of craniofacial jaw bone; selecting feature points on the three-dimensional data of the dentition and the three-dimensional data of the craniofacial jaw bone; constructing tooth arrangement planes and dental arch curves according to the selected feature points, wherein the tooth arrangement planes comprise a median sagittal plane, a horizontal plane and a tooth arrangement occlusal plane, and the dental arch curves comprise an upper jaw tooth arrangement curve and a lower jaw tooth arrangement curve; moving teeth in the three-dimensional data of the dentition according to the preset tooth positions, so that a target dentition after orthodontics is formed, and the preset tooth positions comprise the target upper and lower dentition sagittal position, the target upper and lower dentition vertical position, and the target upper jaw and lower jaw among-dentition position. The automatic tooth arrangement method and the automatic tooth arrangement device are mainly used for the tooth arrangement in the orthodontics.

The present invention discloses β-diketones, γ-diketones or γ-hydroxyketones or analogs thereof, that activate Wnt / β-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.

The invention discloses a three-dimensional craniofacial reconstruction method based on the overall facial structure shape data of Chinese people, comprising the following steps of: (1) acquiring a thickness distribution model of a facial soft tissue based on the statistic analysis of a large amount of human head CT (Computed Tomography) data; (2) unfolding the soft tissue layer and the skull surface layer of a human head through a cylinder, and projecting the soft tissue layer and the skull surface layer to a two-dimensional flat surface, representing the soft tissue shape and the skull shape by using a two-dimensional depth map, and training a radial basis function network to realize the change between the skull to be reconstructed and the common soft tissue thickness distribution form; (3) constructing a shape subspace of local organs of the reconstructed face based on the craniofacial facial structure shape classification of human species, and learning the mapping between the craniofacial local shape and the local shape of the reconstructed face; (4) correcting the reconstructed face model by combining the integral soft tissue distribution and the local characteristic shape deformation, i.e. completing three-dimensional craniofacial reconstruction and correctness of the input skull by adding the two-dimensional depth maps of the soft tissue shape and the shape of the skull to be reconstructed; and (5) synthesizing a complete texture graph of the face through facial texture mapping by using orthogonal pictures, and rendering the skin color and the hair style of the reconstructed human picture to enhance the reality sense of the human picture. By applying the method, the problems of missing reconstruction details and lack of individual characteristics are solved, the manufacturing cost of other anthropology researches and reconstruction technologies is saved, and the working efficiency is improved. The invention has high automation degree and simple operation.

A craniofacial anatomic simulator with cephalometer is disclosed and omnidirectional osteogenesis is provided as an example thereof. The craniofacial anatomic simulator (CAS) includes an articulator in which a stereolithographic medical model is mounted. The medical model hereof is modified for this purpose so that the mandibular portion is mounted together with the craniomaxillary portion in a manner which simulates the excursive movement of the temporomandibular joint and the masseteric sling providing both rotational and translational motion. The cephalometer consists of three digital calipers that provide locational data—height, depth and lateral position for any point on the stereolithographic model.

The invention discloses a model base for craniofacial reconstruction and a craniofacial reconstruction method. The model base for craniofacial reconstruction comprises a craniofacial standard model base and a craniofacial PLSR shape relation model base, wherein physiological points are defined on the craniofacial standard model base. According to the craniofacial reconstruction method, a craniofacial three-dimensional surface model base, on which physiological point corresponding relations are defined, is established through a skin layer point correspondence method and a skull point correspondence method, wherein the skin layer point correspondence method combines partition deformation and multiple restrictions, and the skull point correspondence method is base on TPS overall deformation and multiple restrictions. A craniofacial partial shape relation model based on PLSR is established on the basis of the craniofacial three-dimensional surface model base, and thus the craniofacial PLSR shape relation model base is obtained. By means of a craniofacial standard model, which has the same forensic anthropological information with a to-be-reconstructed skull, in the craniofacial reconstruction model base and the craniofacial PLSR shape relation model, the face of the skull is reconstructed. The craniofacial reconstruction model base is established in the craniofacial partial shape relation modeling method based on PLSR, and the problems that samples are small and variables have multiple correlations in the craniofacial reconstruction method based on statistical theory are solved.

The invention belongs to the field of computer image processing, and particularly relates to a zonal statistic model based a facial reconstruction method. In the method, by a priori knowledge of calculating human facial model shapes, the skull to be reconstructed is subjected to face skin reconstruction, which means that: partitioning the skull and the face skin model according to different organs, and establishing a zone based statistic model; and respectively reconstructing each face skin zone of the skull zone, and splicing each face skin zone into a facial integral model. After the skull face skin is partitioned, the representation capability of the statistic model is improved, and the error of the reconstruction result is reduced. The zonal statistic model based facial reconstructionmethod has important application value in archaeology, forensic medicine, virtual surgery and other fields.

The invention relates to an artificial bone implant for preservation, repair, and regeneration of the human musculoskeletal apparatus by means of orthopedic, dental and craniofacial implantation. More in particular, the invention relates to use of osteoinductive compositions comprising stem cells from adipose tissue and osteoconductive calcium phosphates in bioresorbable cages as part of an artificial bone implant for stabilization and renewed alignment of spinal column segments.

The invention relates to a craniofacial morphological analysis and facial restoration method based on craniofacial denseness corresponding point clouds. The method comprises the steps of 1, acquisition of skull denseness corresponding point clouds; 2, acquisition of facial denseness corresponding point clouds; 3, visual analysis of a craniofacial morphological relation; 4, expression of the craniofacial morphological relation based on soft tissue partitioning; and 5, facial restoration of an unknown body source skull. According to the method, analysis of the craniofacial morphological relation is realized by use of visual analysis based on a principal component coefficient and a quantitative expression method of least square regression, and the problems that craniofacial point cloud data size is large, principal component geometrical significance cannot be easily determined, and the craniofacial morphological relation cannot be easily expressed quantitatively are solved; the problems that the craniofacial morphological relation is complicated, and the craniofacial morphological relation is inconsistent among different regions are solved by use of a craniofacial partitioning method based on soft tissue thickness, and the accuracy of the craniofacial morphological relation is improved; finally, facial restoration of the unknown body source skull is realized by use of the craniofacial morphological relation based on partitioning.

In a preferred embodiment of the present invention, an osteogenetic-orthodontic appliance, device, system, and method optimizes craniofacial homeostasis by means of a 3-D axial spring that influences the patient's genome and thereby addresses problems existing primarily within the mid-facial region, as well as the other contiguous regions. Growth and development of the craniofacial structures can be influenced by foundational (skeleto-dental) correction in concert with functional (myo-spatial) correction, according to the genome of a particular patient by means of the method and systems of the present invention.

A method and apparatus are disclosed enabling an orthodontist or a user to create an unified three dimensional virtual craniofacial and dentition model of actual, as-is static and functional anatomy of a patient, from data representing facial bone structure; upper jaw and lower jaw; facial soft tissue; teeth including crowns and roots; information of the position of the roots relative to each other; and relative to the facial bone structure of the patient; obtained by scanning as-is anatomy of craniofacial and dentition structures of the patient with a volume scanning device; and data representing three dimensional virtual models of the patient's upper and lower gingiva, obtained from scanning the patient's upper and lower gingiva either (a) with a volume scanning device, or (a) with a surface scanning device. Such craniofacial and dentition models of the patient can be used in optimally planning treatment of a patient.

The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N / OFQ). Intranasal administration of certain analgesic peptides such as N / OFQ results in global analgesic effects.

A computer aided system of orthopedic surgery is disclosed and omnidirectional osteogenesis is provided as an example thereof. To perform this surgery a craniofacial anatomic surgical simulator (CASS) is described, in which simulator a stereolithographic medical model is mounted. The medical model hereof is modified for this purpose so that pre-operative intra-oral devices, including custom-fitted fixation plates, can be crafted. An occlusal splint formed on the stereolithographic model acts as an armature for a docking bar which is, during the surgical operation, rigidly affixed to the fixation plate(s). The CASS, in one embodiment hereof, includes an indexing means for alignment of the stereolithographic model. The CASS also simulates the temporomandibular joint and fixedly mounts segments of the model in a post-operative condition.

The invention discloses an automatic analysis method for the cone beam CT image three-dimensional craniofacial structure. Based on a picture model and the full convolutional neural network, the picture model is trained for automatic detection and positioning of an anatomical structure, and the full convolutional neural network is utilized to construct mapping between a cone beam CT image of the anatomical structure and a corresponding marked image. At the test stage, for an input three-dimensional cone beam CT image, firstly, the picture model is utilized to detect the spatial position of theanatomical structure of interests, secondly, the full convolutional neural network is utilized to estimate automatic marking of image subblocks of the structure, and automatic three-dimensional craniofacial structure analysis is realized. The method is advantaged in that the three-dimensional craniofacial structure of interests in the cone beam CT image can be automatically segmented and marked, automatic analysis and segmentation of the stable structure are acquired, and the method can be applied to evaluation of marking and the curative effect of an oral orthodontic treatment plan.

In a preferred embodiment of the present invention, an osteogenetic-orthodontic appliance, device, system, and method optimizes craniofacial homeostasis by means of a 3-D axial spring that influences the patient's genome and thereby addresses problems existing primarily within the mid-facial region, as well as the other contiguous regions. Growth and development of the craniofacial structures can be influenced by foundational (skeleto-dental) correction in concert with functional (myo-spatial) correction, according to the genome of a particular patient by means of the method and systems of the present invention.

The present invention relates to a percutaneous implant abutment for bone anchored implant devices adapted to be anchored in the craniofacial region of a person, such as bone anchored hearing aids. The abutment comprises a skin penetration body having a skin contacting surface. The skin contacting surface has been modified.

A transcranial brain map generation method, a transcranial brain map prediction method for group application and a corresponding transcranial brain map prediction device are provided. The transcranialbrain map prediction method includes the steps of: creating a craniofacial coordinate system at an individual level; establishing a transcranial mapping system for connecting the position of a skullwith the position of a brain; and constructing a transcranial brain map using a two-step stochastic process in a Markov chai. The transcranial brain map projects invisible intracranial map label information onto the visible scalp, allowing researchers or physicians to use the brain structures and functional map information to greatly enhance the effect of the brain map in the use of transcranial mapping techniques.

The invention discloses a measuring device for measuring craniofacial shape, which comprises a seat and is characterized in that the measuring device also comprises a laser triplex scanner, a turn table, a bracket, a sliding block and a slide track. The slide track is positioned on the ground of a workroom; a U-shaped slot on the sliding block is matched with the slide track, and is clamped and positioned on the slide track and is capable of moving 360 degrees around the slide track; the bracket is fixedly connected to the centre above the sliding block; the turn table is fixedly connected to the bracket and the laser triplex scanner is arranged on the turn table; the seat is positioned on the ground where the centre of the slide track locates, facing to the position of 0 graduation of the slide track. The invention also discloses a method for utilizing the measuring device to measure craniofacial shape, craniofacial image data is obtained with the laser triplex scanner to synthesize craniofacial three-dimensional data model which is then measured, thus realizing non-contact measurement.

A surgical tool configured to facilitate delivery of a neurostimulator to a craniofacial region of a subject includes a handle portion, an elongate shaft having a contoured distal portion, and an insertion groove on the elongate shaft. The elongate shaft is configured to be advanced under a zygomatic bone along a maxillary tuberosity towards a pterygopalatine fossa. The distal portion includes a distal dissecting tip. The insertion groove is configured to receive, support, and guide a medical device or instrument.

The invention discloses a craniofacial restoration method based on a deep generative adversarial network. The craniofacial restoration method comprises the following steps: S1, obtaining a training sample; Obtaining condition information of the to-be-restored object; S2, constructing a generative adversarial network, and obtaining a cost function; Obtaining two-dimensional skull data according tothe three-dimensional skull information of the to-be-restored object; S3, taking data in the training sample as input of the generative adversarial network, training the generative adversarial networkto optimize a cost function, and completing training of the generative adversarial network; And S4, taking the two-dimensional skull data and the condition information of the to-be-restored object asthe input of the trained generative adversarial network to obtain restored craniofacial information. The method is based on the generative adversarial network, high-precision craniofacial restorationcan be carried out according to the skull data and the condition information of the to-be-restored object, and facial recognition of a victim in a criminal case, restoration of the facial appearanceof an ancient person in archaeology, effect prediction of a medical facial surgery and the like are facilitated.