108results about How to "Restore integrity" patented technology

Disclosed herein are methods for treating a vascular leak disorder, hypotension, or a procoagulant state using angiopoietin-2 (Ang-2) antagonist compounds. Also disclosed are methods for treating a vascular leak disorder associated with high dose IL-2 therapy using angiopoietin-2 antagonist compounds. Methods for diagnosing and monitoring vascular leak disorders, hypotension, or a procoagulant state that include the measurement of Ang-2 polypeptide or nucleic acid levels are also disclosed. Methods for inducing a vascular leak using an Ang-2 agonist are also disclosed.

The present invention provides methods and devices for enhancing the delivery of treatment devices for treating the annulus of an intervertebral disc. The methods and devices may employ delivery support elements to delivery tools used to deliver expandable treatment devices to the intervertebral disc. Fixation devices and methods are also disclosed, which may help to secure the treatment device in place.

A wound care device having an outer device frame capable of being affixed to skin and an inner device cover detachably affixed to the outer frame and covering the wound.

The invention provides methods for cloning mammals that allow the donor chromosomes or donor cells to be reprogrammed prior to insertion into an enucleated oocyte. The invention also features methods of inserting chromosomes or nuclei into recipient cells.

Provided herein are methods and compositions comprising bile acid transport inhibitors and / or enteroendocrine peptide enhancing agents and / or FXR agonists for the treatment of pancreatitis or prevention of pancreatitis.

A method of local treatment of specific bone defects such as osteoporosis or bone cysts comprises the step of local administration of a formulation comprising a fusion peptide containing a first domain comprising PTH or BMP 2 or BMP 7, and a second domain comprising a covalently crosslinkable substrate domain; and a material suitable of forming a biodegradable matrix suitable for cellular growth or in-growth, wherein the fusion peptide is covalently linked to the matrix. In one embodiment, the matrix contains one or more contrast agents, and is preferably formed in the absence of a growth factor. The matrix may be used in the treatment of fluid-filled cysts such as Tarlov cysts, ovarian cysts, arachnoid cysts, aneurysmal bone cysts or hepatic cysts.

The invention discloses preserved passion fruits and a processing method thereof. The method comprises the concrete steps of firstly, cleaning and cutting fresh passion fruits as raw materials, and separating peels from pulp by removing the pulp; secondly, boiling the peels, removing cuticula, enzymatically hydrolyzing, protecting the color and sugaring; thirdly, mixing the pulp with white granulated sugar and citric acid or citric acid to prepare mixed pulp, and burying the mixed pulp into the peels; finally performing processes of drying, cooling and the like to prepare finished products of preserved passion fruits. According to the method, the selectivity on fruit raw materials is good; the processed preserved passion fruits keep the original aroma and taste of passion fruits, are bright as ever and soft in mouth feel, and have remarkable market competition advantages; a new way is opened up for deep processing of the passion fruits, a very good method is provided for improving the value of the passion fruits, and relatively large profit space is created for enterprises.

The invention provides a multi-channel multi-mode satellite navigation radio-frequency integrated circuit which is characterized by comprising n low noise amplifier input ports, n image rejection mixer output ports, n passive mixer input ports, n variable gain amplifier output ports, a mode controlling logic unit input unit and a circuit for integrating the following circuits such as a low noise amplifier set, an image rejection mixer set, a passive mixer set, a variable gain amplifier set, a mode controlling logic unit, a frequency synthesizer and a frequency divider, wherein a satellite navigation signal is input by an active antenna set, entered into the low noise amplifier set via the low noise amplifier input port, and amplified by a low noise amplifier; and the amplified radio-frequency signals are output to the image rejection mixer set. The invention integrates a plurality of multi-channel multi-mode anti-jamming satellite navigation receiving radio-frequency circuits on one chip, which is excellent in application prospect.

A file storage apparatus capable of restoring integrity of file management information even when a power supply abnormality occurs without lowering the write speed. When updating meta data stored in an HDD, log data for reconstructing the meta data after update from the meta data before update is written into a non-volatile RAM (NVRAM), then, after this writing is completed, the update is executed. Accordingly, even when the update use meta data temporarily stored in a cache memory is partially lost due to trouble such as a power supply abnormality and when update of the meta data of a hard disk is incomplete, the log data corresponding to the meta data for the update is held in the NVRAM, so it becomes possible to restore the integrity of the meta data on the hard disk by using this log data.

A method for repairing and / or waterproofing and / or insulating and / or reinforcing and / or restoring the structural integrity of wall systems, which it consists in providing spaced injection holes within a wall system in a manner suitable to pass through cavities that exist in the wall system, inserting injection tubes in these holes, and then inserting a substance that expands after injection as a consequence of a chemical reaction so that the substance reaches the cavities connected to the injection holes or are proximate thereto, the injection tubes being, preferably gradually retracted along the injection holes in the opposite direction with respect to insertion, to allow the substance diffusing in cavities crossed by the injection holes or proximate thereto.

An improved molded leather bicycle saddle is provided with a carefully designed slot between the nose of the saddle and the rear of the seat portion. The slot has a circular area at the front of the saddle nose, converges slightly then diverges to a middle area before the saddle widens into the seat area. In alternative embodiments, each suited to a different rider type, the slot then converges to a triangular shape, a narrow line or a “T” shaped area. In preferred embodiments, the saddle is reinforced with a leather lamina layer bonded to the underside of the saddle to increase life and retain support. The slot, in some embodiments, may extend through the lamina layer.

The invention relates to a regenerative implant of a cruciate ligament and a preparation method and application thereof. A surgical suture-shaped structure made of a degradable high molecule polymerization material is used as an initial mechanical support structure; a membrane-shaped structure made of a composite electrostatic spinning timbering material is used as a core structure for tissue remodeling and regeneration to be tightly wrapped in a winding mode on the initial mechanical support structure so as to form ligament regeneration elements; the multiple ligament regeneration elements form a ligament regeneration element set which is the regenerative implant of the ligament. The results of a goat animal experiment confirms that the implant is completely degraded within 52 weeks after being implanted to an organism, is induced to form an autogenous ligament tissue in the cavity of a knee joint, and induces the bone tunnel interface of a tibia and a femur to form tendon-bone healing; the maximum pulling force of the regenerated ligament is 20-60% that of a normal ligament tissue within 12 months after the implant is implanted to the organism.

A fence that bounds the outfield of a game played with bat and ball comprises a plurality of mesh panels suspended from a plurality of support posts, with foul posts at either end. The fence can be readily assembled and disassembled. The support posts' anchors can be covered when the fence is disassembled, so that the field is usable for other sports. The function of the fence is twofold: (1) to minimize injury to a player who runs into the fence and (2) to confine such a player within the field of play should the player impact the fence.

The disclosure provides compositions treating traumatic brain injuries such as concussions. In one embodiment, the composition comprises phosphatidylserine, phosphatidylcholine, quercetin, astaxanthin, R-alpha lipoic acid, N-acetyl cysteine, taurine, L-glutamine, carnitine, D-ribose, creatine, epigallocatechin gallate, melatonin, ginkgo leaf extract, curcumin and L-glycine. The disclosure also provides methods for treating traumatic brain injuries such as concussions by administering an effective amount of the compositions described within.

A system for acquiring environmental information measurements. The 5 system (100) utilize a sensor, (205) a front-end circuit, (310) a loop filter (315), a switch controller (206), and a reduced-order loop control circuit to provide reliable data measurements while providing robust system behavior. The system further includes a sensor simulator (330) for simulating the operation of the sensor (205) and testing the operation of the front-end circuit (310) and the loop filter (315).

A door is constructed with a separate member joined to the door edge by a tongue-and-groove coupling and screws so as to be readily removable and replaceable. The separate member sustains the impacts imparted to the door by carts or wagons pushed past the door and can be readily replaced when damaged, thus avoiding replacement of the entire door. A flexible cover snaps over the outer surface of the separate member to add impact resistance and aesthetic appeal. Intumescent strips may be inserted inside or outside of the cover to enhance sealing between the door, and at the adjacent door or door frame, thereby improving the fire resistance rating of the door. Accent strips or reveals of contrasting or complementary colors may be incorporated to add to the aesthetic appeal of the door. The door construction is of particular utility in schools, health care facilities and other institutions.

The present invention provides methods and devices for enhancing the delivery of treatment devices for treating the annulus of an intervertebral disc. The methods and devices may employ delivery support elements to delivery tools used to deliver expandable treatment devices to the intervertebral disc. Fixation devices and methods are also disclosed, which may help to secure the treatment device in place.

Embodiments of the invention relate to human stem cells and their therapeutic use in the treatment and / or prevention of lung diseases. Provided herein are compositions comprising c-kit positive human lung stem cells and methods of preparing and using c-kit positive human lung stem cells for the treatment and / or prevention of lung diseases.

A door is constructed with a separate member joined to the door edge by a tongue-and-groove coupling and screws so as to be readily removable and replaceable. The separate member sustains the impacts imparted to the door by carts or wagons pushed past the door and can be readily replaced when damaged, thus avoiding replacement of the entire door. A flexible cover snaps over the outer surface of the separate member to add impact resistance and aesthetic appeal. Intumescent strips may be inserted inside or outside of the cover to enhance sealing between the door, and as adjacent door or door frame, thereby improving the fire resistance rating of the door. Accent strips or reveals of contrasting or complementary colors may be incorporated to add to the aesthetic appeal of the door. The door construction is of particular utility in schools, health care facilities and other institutions.

The invention discloses processing technique dealing with asphalt pavement sink and crack, which includes following steps: drill pouring holes at cracking area piercing face and ground; pouring material into the holes and fix the ground, sealing the holes; make slots along surface gaps, fill the slots till the sinking area is flush with the ground, block the section till pulp material coagulates till the normal service will not damage the pouring pulp again. By pouring pulp material into pouring holes at sinking area, the rigidity of ground base and surface is enhanced effectively so to keep the ground from further damage, lengthening the road service life greatly.

A retrofit reinforcing structure addition and method for an existing gravity spread foundation for a wind turbine or the like having a central pedestal and a spread section is provided. The retrofit structure addition includes a collar formed around the pedestal of the spread foundation. The collar is formed by a shape sustaining member, such as a CMP, placed around the pedestal to define an annular ring between the CMP and the pedestal that is filled with cementitious material. Radial bolts extend horizontally through the collar and into the side of the pedestal. Soil and / or rock anchor bolts extend vertically through the collar, the spread portion of the foundation and into the underlying soil and / or rock substrate. The radial and anchor bolts are post-tensioned to ensure that the cementitious material of the collar remains in compression and the bolts are always in static tension, strengthening the original gravity spread foundation and extending the fatigue life thereof.

A device and method of making a full contact floating roof for use in covering fluid bodies, such as storage tanks containing hydrocarbon fluids, allowing ease of construction, high integrity, and low maintenance cost.

A retrofit reinforcing structure addition and method for an existing gravity spread foundation for a wind turbine or the like haying a central pedestal and a spread section is provided. The retrofit structure addition includes a collar formed around the pedestal of the spread foundation. The collar is formed by a shape sustaining member, such as a CMP, placed around the pedestal to define an annular ring between the CMP and the pedestal that is filled with cementitious material. Radial bolts extend horizontally through the collar and into the side of the pedestal. Soil and / or rock anchor bolts extend vertically through the collar, the spread portion of the foundation and into the underlying soil and / or rock substrate. The radial and anchor bolts are post-tensioned to ensure that the cementitious material of the collar remains in compression and the bolts are always in static tension, strengthening the original gravity spread foundation and extending the fatigue life thereof.

The invention provides methods for cloning mammals that allow the donor chromosomes or donor cells to be reprogrammed prior to insertion into an enucleated oocyte. The invention also features methods of inserting chromosomes or nuclei into recipient cells.

Apparatus and methods for attacking a screening algorithm. Content to be downloaded is identified. The identified content is then partitioned into at least two sections, wherein each of the at least two sections has a duration which is less than a duration of a threshold duration value assigned by the screening algorithm, and the partitioned content is subjected to a screening algorithm. Once the content has been successfully downloaded, the integrity of the downloaded content may be restored by reassembling the sections.