37results about How to "Has a hollow structure" patented technology

The invention discloses a method for preparing a hollow spherical ferroferric oxide nano material, which comprises the following steps: dissolving ferric chloride hexahydrate in glycol or diethylene glycol and stirring the solution uniformly, wherein the dosage of the glycol or diethylene glycol is 1 to 4 milliliters of glycol or diethylene glycol per millimol of ferric chloride hexahydrate; dissolving anhydrous sodium acetate or sodium succinate or a mixture of anhydrous sodium acetate and sodium succinate in any ratio in solution prepared by the step 1 and stirring the mixed solution with ultrasonic waves to obtain uniform yellow brown sticky solution, wherein the mass ratio of the anhydrous sodium acetate or sodium succinate to the ferric chloride hexahydrate is 1:1 to 4:1; and transferring solution obtained by the step 2 to a liner of a water hydrothermal kettle, closing the kettle for reaction at 180 to 220 DEG C for 6 to 16 hours, naturally cooling the resulting product to room temperature, taking a sample out of the kettle and washing the sample with water and ethanol sequentially to obtain the hollow spherical ferroferric oxide nano material.

The invention discloses a spinel type mesoporous high-entropy oxide (NiCoCrFeMn)3O4 nanosphere with a hollow structure, a preparation method and application thereof, and belongs to the technical fieldof advanced nano materials. The preparation method comprises: carrying out a covalent cross-linking reaction on formaldehyde and tannic acid in weakly alkaline water / alcohol mixed solvent by using pluronic F127 to control morphology, using the tannic acid as an organic ligand and using the formaldehyde as a cross-linking agent to prepare a tannic acid-formaldehyde oligomer; then carrying out a hydrothermal reaction on a metal precursor containing equimolar Ni<2+>, Co<2+>, Cr<3+>, Fe<2+> and Mn<2+> and the prepared tannic acid-formaldehyde oligomer to obtain nickel (II)-cobalt (II)-chromium (III)-iron (II)-manganese (II)-tannic acid-formaldehyde polymer nanospheres; and roasting in an air atmosphere to obtain the spinel type mesoporous high-entropy oxide (NiCoCrFeMn)3O4 nanosphere with thehollow structure. The prepared mesoporous high-entropy oxide (NiCoCrFeMn)3O4 nanosphere has a hollow structure, a high specific surface area, a large pore volume and superparamagnetism, so that the mesoporous high-entropy oxide (NiCoCrFeMn)3O4 nanosphere can be applied to the aspects of catalysis, separation, electrode materials and the like.

The invention discloses nanometer vanadyl phosphate as well as a preparation method and application thereof. The beta-phase nanometer vanadyl phosphate is of a granular hollow structure; the particle diameter of nanometer vanadyl phosphate is 10-30nm; and the wall thickness of nanometer vanadyl phosphate is 1-5nm. The preparation method disclosed by the invention comprises the steps of: placing a vanadium source and a phosphorus source in a metal atom molar ratio of 1:1 in a pressure vessel, adding a solvent and uniformly mixing, heating to 120-280 DEG C after sealing to carry out solvent thermal reaction for 2-240 hours, filtering, washing and vacuum drying the product to obtain a vanadyl phosphate precursor; and calcining the precursor for 0.5-12 hours at a temperature of 400-900 DEG C, and cooling to room temperature to obtain nanometer vanadyl phosphate. The prepared nanometer vanadyl phosphate is small in size, uniform in particle diameter distribution, good in dispersity and large in specific surface area, simple in the preparation method and available in raw material. The nanometer vanadyl phosphate has very high catalytic activity and good reaction selectivity when being used for catalyzing ammoxidation of methyl aromatics to prepare aromatic nitrile, and reaction temperature is reduced compared with the vanadyl phosphate prepared by adopting a conventional method.

The invention relates to the field of cultural relic detection, and discloses a high sensitivity detection method for a silk cultural relic. The method comprises the following steps of: preparing puresilk fibroin powder, and simultaneously extracting the silk fibroin in a cultural sample; sequentially modifying gold nanoparticles, hollow polyacrylic acid-dopamine complex, polymethyl methacrylate-maleic anhydride / 1-octadecene alternating copolymer spherical nanobead, mouse anti-silk fibroin monoclonal antibody on the surface of cleaned glassy carbon electrode by a layer-by-layer self-assemblymethod under the action of NHS / EDC solution; and detecting the silk fibroin solution and the cultural sample solution by using the modified electrode. The high sensitivity detection method for the silk cultural relic has high sensitivity, low detection limit and good reproducibility, and can detect the silk cultural relics with high sensitivity.

The invention provides anti-cracking heat-insulating recycled aggregate mortar. The anti-cracking heat-insulating recycled aggregate mortar comprises the following components in parts by weight: 15 to22 parts of cement, 2 to 3 parts of coal ash, 8 to 10 parts of rubber powder, 3 to 5 parts of bamboo fiber, 8 to 16 parts of heavy calcium carbonate, 30 to 50 parts of recycled fine aggregate, 2 to 3parts of re-dispersible latex powder, 0.01 to 0.04 part of an organosilicone resin solution, 0.1 to 0.2 part of a water-retaining agent, 0.1 to 0.5 part of an anti-freezing agent and 0.1 to 5 parts of pigment. The invention further discloses a preparation method of the mortar. The recycled aggregate mortar provided by the invention has high anti-cracking property, high heat-insulating property and low preparation cost.

The invention relates to a preparation method of a wood-like wood-plastic composite sheet material. The preparation method solves the problem that the existing wood-plastic material has a low strength-weight ratio, a high cost and small breadth. The preparation method comprises the following steps of paving bamboo poles and plastic powder in a mold layer upon layer, carrying out hot pressing molding, carrying out cooling, and carrying out demolding. The wood-like wood-plastic composite sheet material is prepared from waste, thin and short bamboo poles and waste and old plastic, has the advantages of simple processes, low cost, large product breadth, low density, high strength, high elastic modulus and creep resistance, and can solve the problem that wood can produce hygroexpansion easily. The preparation method can be used in the fields of house, bridge, vehicle and ship manufacture.

The invention provides a preparation method of CO2 response polymer hollow microspheres. The preparation method comprises the following steps: firstly, enabling a monomer, namely styrene, methyl methacrylate, tert-butyl methacrylate, butyl acrylate or hydroxyl styrene, to react with an initiator and an emulsifier, so as to obtain a seed microsphere emulsion; secondly, simultaneously dropping a mixture of a compound A and a crosslinking agent, and the initiator into the seed microsphere emulsion, and carrying out a reaction so as to obtain a core-shell microsphere emulsion; mixing the core-shell microsphere emulsion with organic solvents, namely tetrahydrofuran (THF), chloroform, ethyl acetate, methylbenzene and the like, and carrying out selective etching. By adopting the preparation method, intelligent hollow microspheres of hollow structures with CO2 response are prepared, irritation residue-free and environmental-friendly response modes of a hollow microsphere material can be achieved, and in addition, the microspheres are controllable in morphology and CO2 irritation response.

The invention relates to the cultural relic detection field, and discloses a high sensitivity detection method for a cowhide cultural relic. The method comprises the steps that pure bovine collagen powder is prepared, and bovine collagen in a cultural relic sample is extracted; the surface of a cleaned glassy carbon electrode is sequentially modified with gold nanoparticles, a polyacrylic acid-dopamine composite with a hollow structure, polymethyl methacrylate-maleic anhydride / 1-octadecene alternating copolymer spherical nano beads and a rabbit anti-bovine collagen polyclonal antibody under the effect of an NHS / EDC solution by utilizing a layer-by-layer assembly method; and a bovine collagen solution and a cultural relic sample solution are detected by means of the modified electrode. Themethod is high in sensitivity, low in detection lower limit, good in repeatability and capable of achieving supersensitive detection on the cowhide cultural relic.

The invention belongs to the technical field of advanced materials, and particularly relates to a hollow TiO2@C composite microsphere and a preparation method thereof. The preparation method comprisesthe following steps: dispersing silicon dioxide nanospheres in an organic solvent containing a surfactant and an alkali catalyst under the action of ultrasonic waves, adding a titanium source, and carrying out hydrolysis and polycondensation to obtain a SiO2@TiO2 core-shell structure compound; dispersing the compound into a strong alkali solution, and carrying out hydrothermal etching assisted crystallization to obtain titanate with a hollow structure; and finally, dispersing titanate into a carbon source aqueous solution, carrying out hydrothermal reaction, and roasting in an inert atmosphere to obtain the hollow TiO2@C composite microspheres constructed by the nanosheets. The composite microsphere has a double-shell hollow structure, and has large specific surface area, pore volume andpore diameter. The material is applied to a negative electrode of a sodium-ion battery, and shows excellent rate capability and pseudocapacitance characteristic. The raw materials are easy to obtain,the method is simple, and the product has wide application prospects in the fields of environment, energy, catalysis and the like.

The invention provides a preparation method of a wear-resistant heat-insulation polystyrene material. The method comprises the following steps: (1) preparing carbon spheres from sucrose by a hydrothermal process; (2) preparing a carbon sphere liquid from the carbon spheres, preparing an SDBS (sodium dodecyl benzene sulfonate) liquid from SDBS, and mixing to obtain a mixed liquid A; (3) mixing zirconium oxychloride, hexamethylenetetramine, urea and deionized water to obtain a mixed liquid B, and mixing TEOS (tetraethyl orthosilicate) and ethanol to obtain a mixed liquid C; (4) mixing the mixed liquids A, B and C, using the carbon spheres as the template, and calcining to remove the template, thereby obtaining composite hollow microspheres; (5) carrying out modification treatment on the composite hollow microspheres by using KH570 to obtain modified composite hollow microspheres; and (6) weighing the raw materials, mixing the raw materials, extruding, cooling, drying, and granulating to obtain the wear-resistant heat-insulation polystyrene material. The prepared polystyrene material has favorable heat-insulating property and wear resistance.

The invention discloses a preparation method of natural macromolecular hollow microspheres. The preparation method comprises the following steps: dissolving natural macromolecules in a mixed solvent of KOH, LiOH, NaOH and urea at a low temperature, and obtaining a chitin, cellulose or chitosan solution by virtue of freezing-thawing circulation; and spraying the chitin solution into liquid nitrogen by virtue of an electrostatic drop method, and obtaining chitin, cellulose and chitosan hollow microspheres with a hollow structure by virtue of freeze drying. According to the preparation method of the invention, the chitin, the cellulose and the chitosan hollow microspheres having good biological compatibility and degradation and having a hollow interior and regular pores on spherical walls can be obtained and have a wide application prospect in various fields such as environmental treatment, tissue engineering, agricultural and biological materials and the like.

The invention discloses a blended hollow fiber comfortable shell fabric. The blended hollow fiber comfortable shell fabric is formed by blending and weaving four types of fibers, namely hemp fibers, polylactic acid fibers, banana fibers and kapok fibers, wherein the weight percents of all the shell fabric fiber components in the blended hollow fiber comfortable shell fabric are as follows: 25%-29% of the hemp fibers, 17%-21% of the polylactic acid fibers, 19%-23% of the banana fibers and 27%-39% of the kapok fibers. The shell fabric is formed by blending and weaving four types of fibers, namely the hemp fibers, the polylactic acid fibers, the banana fibers and the kapok fibers and all the shell fabric fibers are plant fibers and are of a hollow structure respectively; the shell fabric woven by the shell fabric fibers has the characteristics of being light and thin, absorbing moisture and releasing sweat, being cool and ventilated, being soft and comfortable and absorbing and insulating sounds.

The invention discloses a blade pump comprising a stator, a rotor and blades. The stator has an inner surface of a cylindrical hole, the rotor is a cylinder with a radial slot, the rotor is eccentrically mounted in the cylindrical hole of the stator, the blades freely slide in the radial slot of the rotor, wherein the blade pump comprises a blade shaft, and the blade shaft and the cylindrical hole of the stator are coaxially mounted; the blades are connected to the blade shaft, every blade forms an impeller with fixed external diameter, the impeller is rotatably cooperated with the inner surface of the cylindrical hole of the stator. The blade pump has the advantages of simple structure, convenience in manufacturing, small energy consumption, steady performance and long service life, more important, the blade pump can be applied to the transportation of gas, liquid such as water, and the like.

The invention discloses a preparation method of hollow rod-like zinc borate, relates to a preparation method of zinc borate and aims to solve the problem that an existing zinc borate process is complicated, consumes long time for reaction and ageing and is poor in flame-retardant property. The preparation method comprises the steps that 1, boric acid, zinc oxide and deionized water are evenly mixed to obtain a mixed solution; 2, the mixed solution is put in a hydrothermal reaction kettle, hydrothermal reaction is performed under stirring, and then cleaning and drying are performed to obtain the hollow rod-like zinc borate. The prepared zinc borate by adopting the preparation method has a hollow rod-like structure and can increase the contact area between the zinc borate and a flame retardant and a flame retardant material when serving as an inorganic flame retardant material. By adding 1%-5% of zinc borate prepared in the flame retardant, the flame retardant performance of the inorganic flame retardant material can be effectively improved, namely the oxygen index is improved for 1-4 units, and the zinc borate is more suitable for development and application of the inorganic flame retardant material. The hollow rod-like zinc borate can be obtained by adopting the preparation method.

The invention relates to a method for preparing ellipsoidal ion-doped hydroxyapatite microspheres with porous surfaces. According to the method disclosed by the invention, ellipsoidal hydroxyapatite microspheres are prepared from ellipsoidal calcium carbonate microspheres as a precursor and the support of a plurality of trace ions (Mg, Sr, Zn, Ag, Fe, Si, Y, F, Cl and the like) and fluorescent ion (Eu) is achieved. No surfactant is used in the preparation process of ellipsoidal hydroxyapatite microspheres and ellipsoidal calcium carbonate microspheres, and the sizes of the obtained ellipsoidal hydroxyapatite microspheres and ellipsoidal calcium carbonate microspheres are uniform and the obtained ellipsoidal ion-doped hydroxyapatite microspheres have the characteristics of relatively high specific surface area, fluorescent tracing and bacteriostasis and other properties and are capable of adsorbing positively charged polymers. The hollow or solid ellipsoidal ion-doped hydroxyapatite microspheres prepared by the method disclosed by the invention can be applied as a drug carrier material, a bone repair material, an environmental water treatment material, food or cosmetics additives and the like.

The invention discloses a high-temperature-resistant ceramic brake pad and a production process thereof, and relates to the technical field of ceramic brake pad production to solve the problem that high temperature resistance of a brake pad cannot be estimated. The high-temperature-resistant ceramic brake pad comprises a steel backing; a noise reduction piece is arranged on the outer wall of the top of the steel backing, and a thermal insulating layer is bonded to the outer wall of the top of the noise reduction piece; and a friction material is arranged on the outer wall of the top of the thermal insulating layer and prepared from sepiolite fibers, asbestos fibers, potassium carbonate crystal whiskers, brass fibers, wollastonite, aramid fibers, aluminium silicate fibers, aluminium silicate, zirconite, cryolite, feldspar, vermiculite, graphite, antimony disulfide, talcum, mica, barite, porous iron powder, boron modified phenolic resin, open-loop polymerized phenolic resin and the like.The high-temperature-resistant ceramic brake pad has high impact-resistance strength, meanwhile the product density is low, the product hardness is low, braking noise is small, and braking duality isnot damaged.

The invention discloses a hollow iron-nickel nitride catalyst as well as a preparation method and an all-water electrolysis application thereof. The preparation method comprises the following steps: selecting iron-nickel alloy nanoparticles with the particle size of 100-300 nm, wherein the ratio of iron atoms to nickel atoms is 1:3; and using a Kirkendall effect to conduct low-temperature oxidation etching to synthesize hollow iron-nickel-based nanoparticles, conducting low-temperature nitriding treatment to obtain the hollow iron-nickel nitride catalyst. The catalyst is used in full-hydrolysis cathode hydrogen precipitation and anode oxygen precipitation reactions, and shows better electrocatalytic activity compared with an iron-nickel nitride powder material. The synthesis method is simple and low in cost, the full-water electrolysis catalytic activity of the hollow iron-nickel nitride catalyst is higher, and the hollow iron-nickel nitride catalyst is suitable for large-batch production.

The invention provides a nanometal hollow fiber felt current collector and a preparation method thereof, a lithium ion battery pole piece and a lithium ion battery. The preparation method of the nanometal hollow fiber felt current collector comprises the following steps: spinning a polymer to obtain a nano-fiber felt template, activating and sensitizing the nano-fiber felt template, and performingplating to obtain a nano-fiber felt with a metal film; and soaking the nano-fiber felt with the metal film in a solvent to obtain the nano-metal hollow fiber felt current collector. The nanometal hollow fiber felt current collector is prepared by using the preparation method. The lithium ion battery pole piece is prepared by using the nano metal hollow fiber felt current collector. The lithium ion battery comprises the lithium ion battery pole piece. The nano-metal hollow fiber felt current collector provided by the invention is high in chemical stability and excellent in electrical property.

The invention discloses a preparation method of hollow rod-like zinc borate, relates to a preparation method of zinc borate and aims to solve the problem that an existing zinc borate process is complicated, consumes long time for reaction and ageing and is poor in flame-retardant property. The preparation method comprises the steps that 1, boric acid, zinc oxide and deionized water are evenly mixed to obtain a mixed solution; 2, the mixed solution is put in a hydrothermal reaction kettle, hydrothermal reaction is performed under stirring, and then cleaning and drying are performed to obtain the hollow rod-like zinc borate. The prepared zinc borate by adopting the preparation method has a hollow rod-like structure and can increase the contact area between the zinc borate and a flame retardant and a flame retardant material when serving as an inorganic flame retardant material. By adding 1%-5% of zinc borate prepared in the flame retardant, the flame retardant performance of the inorganic flame retardant material can be effectively improved, namely the oxygen index is improved for 1-4 units, and the zinc borate is more suitable for development and application of the inorganic flame retardant material. The hollow rod-like zinc borate can be obtained by adopting the preparation method.

The invention discloses a preparation method of calcium fluoride microspheres, which uses an acid-base titration method to keep the solution acidic, dissolves insoluble calcium and phosphorus salts to generate calcium ions, and adds soluble fluoride salt solutions to provide fluoride ions, thereby preparing fluoride Calcium (CaF 2 )Microspheres. The steps are to put insoluble calcium calcium phosphate into the weakly acidic solution maintained by acid-base titration, stir with a magnetic stirrer for 1 hour to form a suspension, add a certain amount of soluble fluorine salt solution, and stir with a magnetic stirrer 24 hours. The suspension was filtered successively with distilled water and absolute ethanol, and then dried at 40°C to obtain calcium fluoride (CaF 2 )Microspheres. The method has simple steps, mild conditions and is easy for industrial production.

The invention provides a crack-resistant and heat-retaining recycled aggregate mortar, the components and weight parts of which are: 15-22 parts of cement, 2-3 parts of fly ash, 8-10 parts of rubber powder, 3-5 parts of bamboo fiber, 8-16 parts of heavy calcium carbonate, 30-50 parts of recycled fine aggregate, 2-3 parts of redispersible latex powder, 0.01-0.04 parts of silicone resin solution, 0.1-0.2 parts of water-retaining agent, 0.1-0.5 parts of antifreeze parts, 0.1 to 5 parts of pigments. The invention also discloses a preparation method of the mortar. The recycled aggregate mortar provided by the invention has good crack resistance and heat preservation performance, and the preparation cost is low.

The invention relates to the field of cultural relic detection, and discloses a high sensitivity detection method for a silk cultural relic. The method comprises the following steps of: preparing puresilk fibroin powder, and simultaneously extracting the silk fibroin in a cultural sample; sequentially modifying gold nanoparticles, hollow polyacrylic acid-dopamine complex, polymethyl methacrylate-maleic anhydride / 1-octadecene alternating copolymer spherical nanobead, mouse anti-silk fibroin monoclonal antibody on the surface of cleaned glassy carbon electrode by a layer-by-layer self-assemblymethod under the action of NHS / EDC solution; and detecting the silk fibroin solution and the cultural sample solution by using the modified electrode. The high sensitivity detection method for the silk cultural relic has high sensitivity, low detection limit and good reproducibility, and can detect the silk cultural relics with high sensitivity.

The invention discloses a high-efficiency water decomposition catalyst hollow cobalt phosphide and a preparation method thereof, and relates to the technical field of water decomposition catalyst preparation. The microstructure of the cobalt phosphide is a single-shell nanocage, and the cobalt phosphide takes CoP as a shell, is a hollow rhombic dodecahedron and is shaped like a cage. The preparation method comprises the preparation steps: by taking a Na2MoO4 aqueous solution as a reaction medium, constructing a Co(OH)2 hollow structure through a Kirkendall effect, then annealing the prepared Co(OH)2 hollow structure in air at the temperature of 500 DEG C to prepare a Co3O4 single-shell nanocage, and then annealing a Co3O4 single-shell nanocage precursor and NaH2PO2 at the temperature of 700 DEG C in an N2 atmosphere to form CoP with the CoP hollow structure. The hollow cobalt phosphide prepared by the method disclosed by the invention has the advantages of mesoporous property, larger specific surface area and higher water decomposition efficiency.

The invention provides a preparation method of a hollow-structure Co-Fe LDH material, comprising the following steps: step 1, preparing a precursor Fe-MOFs material by a solvothermal method, and then drying the prepared Fe-MOFs material; step 2, Disperse the Fe-MOFs material in anhydrous ethanol solution, dissolve the cobalt source and urea in deionized water, mix the two solutions, and heat in a water bath for a certain period of time to obtain the Co-Fe LDH material; the hollow structure Co-Fe of the present invention The preparation method of LDH material, the obtained hollow Co-Fe LDH particles have complete morphology and uniform particle size, and have good application prospects in the field of catalysis and energy storage materials. The preparation method of the invention is mature and easy to operate, and the process is stable It has good performance, low cost, and has a good foundation for popularization and application.

The invention provides a nanometer metal hollow fiber felt current collector and a preparation method thereof, a lithium ion battery pole piece and a lithium ion battery. The preparation method of the nano metal hollow fiber felt current collector: the nanofiber felt template is obtained by polymer spinning, and then the nanofiber felt template is activated and sensitized and then plated to obtain a nanofiber felt with a metal film; The nano-fiber felt with the metal film is soaked in a solvent to obtain the nano-metal hollow fiber felt current collector. The nano metal hollow fiber felt current collector is prepared by the preparation method. The lithium ion battery pole piece is made by using the nanometer metal hollow fiber felt current collector. A lithium ion battery includes the lithium ion battery pole piece. The nano-metal hollow fiber mat current collector provided by the application has high chemical stability and excellent electrical properties.

The invention discloses an adjustable bicycle head vertical rod. Two sleeves which are used for conveniently fixing a front fork vertical rod and a bicycle head cross handle in an insertion sleeved way respectively are arranged at the two ends of the bicycle head vertical rod; a sleeve orifice of at least one end is a slot-shaped pipe orifice; at least one open slot which can conveniently clamp a pipe fitting through a clamping mechanism is formed at the slot-shaped pipe orifice along the axial direction; an adjustment block which is detachable and is provided with a crescent cross section is arranged on the lateral part of the slot-shaped pipe orifice; when the adjustment block is inserted into one side on the inner part of the slot-shaped pipe orifice, a circular orifice by which the pipe fitting is convenient to fasten is formed by the crescent cross section and the slot-shaped pipe orifice; the sleeve with the slot-shaped pipe orifice consists of a left half pipe orifice and a right half pipe orifice; the left half pipe orifice is integrated with the bicycle head vertical rod; two open slots are formed by folding the left half pipe orifice and the right half pipe orifice; and the side face of the adjustment block consists of a convex arc-shaped surface which can be tightly attached to the inner side of the slot-shaped pipe orifice and a concave arc-shaped surface which can be tightly attached to the surface of the bicycle head cross handle. By the bicycle head vertical rod, the distance between the front fork vertical rod of which the two ends are fixedly connected with each other and the bicycle head cross handle can be adjusted, so that the distance between the bicycle head cross handle and a bicycle cushion can be adjusted, and a humanized design is realized.

The invention discloses a preparation method of a high-power lithium ion battery negative electrode material. The preparation method comprises the following steps: firstly, preparing Zn / Co-ZIF; mixinga ferrite solution, a cobalt salt solution and a nickel salt solution with a Zn / Co-ZIF solution in a protective gas, adding a 2-methylimidazole solution, uniformly stirring, standing, carrying out suction filtration, washing, and drying to obtain Zn / Co-ZIF coated Fe / Co / Ni-ZIF with the core-shell structure; and finally, sequentially calcining Zn / Co-ZIF@Fe / Co / Ni-ZIF in protective gas and air to obtain the high-power lithium ion battery negative electrode material. Zn / Co-ZIF@Fe / Co / Ni-ZIF with a core-shell structure is used as a precursor to perform two-step calcination in protective gas and airto obtain the high-power lithium battery negative electrode material, and the preparation method is simple in preparation process, mild in condition and suitable for industrial production.

The invention discloses a preparation method of pH- and temperature-responsive double-shell hollow microspheres. PVSI microspheres are prepared from vinyltriethoxysilane, and PVSI@PMAA is prepared by cross-linking methacrylic acid on the surface of PVSI microspheres. Core-shell microspheres, polycondensation of vinyltriethoxysilane on the surface of PVSI@PMAA core-shell microspheres to prepare PVSI@PMAA@SiO 2 -CH=CH 2 Three-layer composite microspheres prepared by cross-linking poly-N-isopropylacrylamide PVSI@PMAA@SiO 2 @PNIPAM four-layer composite microspheres, crosslinked allyl fluorescent dye at the same time, and finally prepared air@PMAA@air@PNIPAM double-shell hollow microspheres by HF corrosion. The double-shell hollow microspheres of the invention have good monodispersity and simultaneously have pH responsiveness and temperature responsiveness.

The invention relates to a method for preparing a hollow mesoporous silica nanosphere loaded propranolol hydrochloride composite system. The method comprises the following steps of: (1) preparing solid silica spheres; (2) preparing hollow mesoporous silica nanospheres; (3) preparing a propranolol hydrochloride solution; (4) loading propranolol hydrochloride onto the hollow mesoporous silica nanospheres; and (5) performing washing. The hollow mesoporous silica nanospheres prepared by the method disclosed by the invention are adjustable in particle size, good in monodispersity, uniform in particle size and high in propranolol hydrochloride drug loading capacity, and have a slow-release structure.