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53 results about "Calcium deposition" patented technology

Health care medicinal liquor for strengthening muscle and bone

The invention provides a health care medicinal liquor for strengthening muscles and bones, and the health care medicinal liquor is prepared through repeated clinical test verification. The health care medicinal liquor accords with the principles of the traditional Chinese medicine. The health care medicinal liquor is prepared from the following raw traditional Chinese medicine materials: seeds ofChinese dodder, lotus stamen, herba epimedii, eucommia ulmoides, fructus psoraleae, cynomorium songaricum, cornu cervi degelatinatum, teasel roots, fructus ligustri lucidi, rhizoma cibotii, drynaria rhizome, centipedes, obscured homalomena rhizome, dog bones, chicken shells, pawpaw, fruit of Chinese wolfberry, poria cocos, schisandra chinensis, gentiana macrophylla, seeds of Chinese milk vetch, polygonum multiflorum, antler glue and raspberries. After being taken, the health care medicinal liquor has the functions of efficiently enhancing the bone mass, improving the bone quality, maintainingthe integrity degree of the microstructure of the bones, enhancing the activity of bone cells, and promoting the calcium deposition. The health care medicinal liquor can be used for relieving the pain of the waist, the back and the limbs, improving the microcirculation, increasing the bone density, adjusting the functions of the hypothalamus pituitary gland gonad, and improving the disorder status of the bone adjusting hormone and the cell factors in the metabolic process of the bones.
Owner:蔡焱

Preparation method of degradable magnesium alloy and degradable polymer composite

The invention provides a preparation method of a degradable magnesium alloy and degradable polymer composite. Degradable magnesium or a degradable magnesium alloy is taken as a metal substrate and processed, and three-dimensional through pores in different shapes and with different porosity are densely formed in the metal substrate adopting the degradable magnesium or the degradable magnesium alloy. The degradable magnesium or the degradable magnesium alloy is taken as a substrate material and tightly combined with a degradable polymer through the crossed through three-dimensional pores, the overall mechanical properties of the composite are far higher than those of a single degradable polymer, the composite can meet requirements of most applications such as bone filling, bone repair, bone transplantation and the like, the medical magnesium or the medical magnesium alloy is degraded in a human body fluid corrosion environment, calcium deposition and osteocyte formation can be promoted, bone healing can be accelerated, and the biological activity is improved; the composite can form porous tissue automatically in a degradation process, ingrowth of new bone tissue and propagation of osteocytes are facilitated, and rehabilitation time of bone tissue is shortened.
Owner:FOSHAN UNIVERSITY

Composite phosphorus-based calcification inhibitor for inhibiting anaerobic granular sludge calcification and application method

The invention discloses a composite phosphorus-based calcification inhibitor for inhibiting anaerobic granular sludge calcification and an application method, and relates to the field of industrial wastewater treatment. The calcification inhibitor is prepared from, by mass, 40-85 parts of phosphoric acid, 10-25 parts of sodium tripolyphosphate and 5-25 parts of sodium pyrophosphate. The calcification inhibitor is added into inlet water of an anaerobic reactor according to a calcium-phosphorus ratio (mass ratio) of (20-35):1 in a high-calcium-content wastewater anaerobic granular sludge treatment system, so that free calcium ions are inhibited from forming calcium deposition in granular sludge, and the activity of the anaerobic granular sludge is maintained. Calcium is actively prevented from being deposited and calcified and inactivated in a sludge core, the anaerobic reactor does not need to discharge sludge or scale removal, the problem that the treatment capacity of an anaerobic reaction system is reduced due to sludge calcification and inactivation in high-calcium-content wastewater treatment in the fields of waste paper pulping, food processing, landfill leachate, fermentationwastewater and the like is effectively solved, and the composite phosphorus-based calcification inhibitor and the method have remarkable application value.
Owner:GUANGXI UNIV

Biochemical treatment method and apparatus for high calcium and high magnesium waste water

PendingCN106007272AReduce calcium ionReduce the content of magnesium ionsWater contaminantsTreatment with anaerobic digestion processesActivated sludgeNitrogen removal
The invention discloses a biochemical treatment method for high calcium and high magnesium waste water. The biochemical treatment method comprises the following steps: S1) waste water pretreatment, S2) biological calcium-removal magnesium-removal anaerobic reaction, S3) pH value adjusting and biochemical calcification, magnesiation treatment, and S4) deposition and discharge of calcification and magnesiation sludge. The invention also discloses an apparatus for high calcium and high magnesium waste water. The biochemical treatment method can reduce the calcium ions and magnesium ions content in the waste water with high efficiency as well as reduce the calcium hardness in the waste water; simultaneously can reduce partial COD, increases B/C ratio, and increases the biodegradability of the waste water; avoids generation of calcium deposition phenomenon during a waste water treatment process, prevents corrosion and obstruction of pipeline equipment, and reduces influence of the calcium ions and the magnesium ions to activated sludge performance and nitrogen removal function of a biological treatment A/O system. The method has the advantages of simple process, easy operation, low requirements of technology condition, and easy control. The apparatus has the advantages of high system stability, simple structural setting, and wide application scope.
Owner:桂琪

Efficient calcium mineralizing bacterium and application thereof

PendingCN111592991AStrong Calcium Mineralizing PropertiesBacteriaMicroorganism based processesBiotechnologyBacillus cereus
The invention discloses an efficient calcium mineralizing bacterium and an application thereof, and belongs to the field of microorganisms. The bacterium disclosed by the invention is bacillus cereusEMCa1. The strain is in a short rod shape, and is in a short or long chain, the size of the bacterium is about (1.0-1.2) x (3.0-5.0) [mu]m, the strain is a gram staining positive bacterium, white circular bacterial colonies appear after the strain is cultured for 24 h on an LB agar plate culture medium at 30 DEG C, a diameter is about 5-7 mm, the edge is irregular, and the bacterial colony surfaceis like wax. The induced calcium carbonate deposition characteristic of the strain is as follows: after 20 days of culture, the strain can convert free calcium ions in a coral sand solution into a calcium carbonate precipitate, and in a calcium carbonate deposition experiment, the concentration of calcium ions is reduced from 36.9 mg/L to 7.19 mg/L, and the proportion of calcite in coral sand isincreased from 2% to 20%. According to the efficient calcium mineralizing bacterium and the application thereof, calcium ions can be mineralized to generate calcium carbonate, so that the efficient calcium mineralizing bacterium is applied to the restoration of stone cultural relics.
Owner:INST OF SOIL SCI CHINESE ACAD OF SCI

Method for researching sand soil solidification effects by carbonic anhydrase mineralization bacteria

The invention discloses a method for researching sand soil solidification effects by carbonic anhydrase mineralization bacteria. The method includes the steps: firstly, solidification sample preparation; secondly, direct shear experiment; thirdly, calcium carbonate content measurement; fourthly, X-ray diffraction experiment sample preparation; fifthly, electron scanning microscope experiment sample preparation. According to the method, the solidification effects of different grouting modes are explored, sand soil solidification experiments of factors such as calcium source kinds, solidification environment temperature, consolidating fluid concentration and particle diameter are implemented, the solidification effects are compared, and the modes, the concentration and the like with optimalsolidification effects are preferentially selected. The solidification effects of a solidification sample are represented by comparing and analyzing shearing strength and calcium carbonate depositionof the solidification sample under different conditions, a crystal form of calcium carbonate is acquired by an X-ray diffraction instrument, and a microscopic image of the solidification sample is observed by a scanning electron microscope.
Owner:SOUTHWEAT UNIV OF SCI & TECH

Composite decalcifying agent for calcified anaerobic granular sludge and decalcifying regeneration process

The invention discloses a composite decalcifying agent for calcified anaerobic granular sludge and a decalcifying regeneration process. The composite decalcifying agent comprises the following components in parts by mass: 40-85 parts of phosphoric acid, 10-25 parts of sodium tripolyphosphate and 1-10 parts of sodium lignin sulfonate. The composite decalcifying agent is added into inlet water of ananaerobic reactor according to the calcium-phosphorus mass ratio of (10-25):1 in a high-calcium-content wastewater anaerobic granular sludge treatment system, so that free calcium ions are inhibitedfrom forming calcium deposition in granular sludge, calcium deposition is promoted to form chelate to return to a wastewater phase, and then decalcification regeneration of the calcified anaerobic granular sludge is realized. According to the composite decalcifying agent and the process, deposition of calcium in the sludge core is actively prevented, and chelation and dissolution of calcium deposition are enhanced, so that the anaerobic reactor does not need sludge discharge or descaling, the problem that the treatment capacity of an anaerobic reaction system is reduced due to sludge calcification inactivation in high-calcium-content wastewater treatment in the fields of waste paper pulping, food processing, landfill leachate, fermentation wastewater and the like is effectively solved, andthe composite decalcifying agent and the process have remarkable application value.
Owner:GUANGXI UNIV

Applications of growth hormone release hormone agonist in preparation of anti-vascular calcification drugs

The present invention discloses a new medical use of a growth hormone release hormone (GHRH) agonist, particularly applications of a growth hormone release hormone agonist in preparation of anti-vascular calcification drugs. According to the present invention, GHRH-A can increase the cAMP level and the protein kinase A (PKA) activity in smooth muscle cells, can decrease the expression and the activity of NAPDH oxidase in smooth muscle cells, can decrease the ROS level in smooth muscle cells, can decrease the expression and the activity of Runx2 in smooth muscle cells, can decrease the expression and the activity of alkaline phosphatase (ALP) in cells, and can decrease the inorganic phosphorus content in blood so as to reduce the calcium deposition and the phosphorus deposition in aorta, reduce the activity of ALP in aorta, and achieve the purposes of treatment or prevention of vascular calcification and arteriosclerosis.
Owner:余红

Pulp pH meter intermittent flushing device based on automatic control and use method of pulp pH meter intermittent flushing device

The invention discloses a pulp pH meter intermittent flushing device based on automatic control and a use method of the pulp pH meter intermittent flushing device. The pulp pH meter intermittent flushing device comprises a pH meter (1), a pulp mixing device (2) and a flushing groove (3) and further comprises a driving mechanism capable of driving the pH meter to move back and forth between the pulp mixing device and the flushing groove. A measuring point position switch (4) is arranged in the pulp mixing device. A first limiting position switch (5) is arranged above the slurry mixing device, asecond limiting position switch (6) is arranged above the flushing groove, and a flushing point position switch (7) and a flushing groove position switch are arranged in the flushing groove. The pulppH meter intermittent flushing device based on automatic control and the use method of the pulp pH meter intermittent flushing device have the beneficial effects that a conventional pulp PH detectionmethod can be replaced, the problems that in a conventional detection method, due to PH meter dirt or surface calcium deposition, the PH value error is large, and detection is not accurate and not intime can be solved, the detection frequency can also be adjusted according to practical conditions, the pulp PH value is measured in time, and the quality and the recovery rate of concentrate products are ensured.
Owner:铜陵有色金属集团股份有限公司

Method for mild and massive preparation of mineralization silk fibroin films

The invention provides a method for mild and massive preparation of mineralization silk fibroin films. The method comprises the steps of silk fibroin film preparation, silk fibroin film enzyme solution preprocessing, phosphate deposition and calcium deposition so that the silk fibroin films with the completely-mineralized surfaces can be obtained. The obtained mineralization silk fibroin films can be used for bone repair materials for cartilage repairing, periosteum repairing, ligament repairing and the like. According to the method, no repeated soaking is needed, the preparation process is simple, the preparation conditions are mild, and the most preparation processes are performed at the temperature of 37 DEG C; the obtained mineralization area is large, the quantity is large, and the shape is controllable.
Owner:杭州千岛湖蓝色天使实业有限公司

Bone repair scaffold material capable of mediating nervalization and preparation method and application thereof

The invention discloses a bone repair scaffold material capable of mediating nervalization and a preparation method and application thereof. The preparation method comprises the steps that heterologous expression bone matrix fusion protein is adsorbed into calcium and magnesium doped mesoporous bioactive glass prepared through a sol-gel and template self-assembly method to serve as an inner core; nerve growth factors capable of promoting nerve growth are loaded into silk protein to serve as a shell, and then the bone repair scaffold material which is of a core-shell structure and can be used for mediating nervalization is prepared through a coaxial electrostatic spinning technology. The bone repair scaffold material capable of mediating the nervalization has good cell compatibility, osteogenic activity, neurogenic activity and calcium deposition promotion effects, can promote proliferation, differentiation and mineralization processes of bone marrow mesenchymal stem cells in the osteogenic direction, can also promote the survival process of neurons, as a bone repair material, the material has a wide prospect in clinical application of repairing bone defects and restoring consciousness of injured parts.
Owner:NAT UNIV OF DEFENSE TECH

Application of procyanidin SA hydrogel in preparation of medicine for treating tendon ectopic calcification

InactiveCN110946855ANo acuteNo subacute toxicityOrganic active ingredientsAerosol deliveryDiseaseEosin
The invention discloses an application of procyanidin in regulation and control of stem cell functions in a pathological microenvironment of tendon diseases, and provides a preparation method of procyanidin SA hydrogel and an application of the procyanidin SA hydrogel in treatment of tendon ectopic calcification. Based on the application, the invention proves that: the addition of the procyanidininto tendon stem / progenitor cells does not influence cell proliferation, and can effectively inhibit the calcium deposition of the tendon stem / progenitor cells and the subsequent potential for treating tendon diseases. Through Micro CT, hematoxylin-eosin staining, crocus sativus-solid green staining, collagen II and osteocalcin (OCN) immunohistochemical staining, the situation of the procyanidin SA hydrogel for treating tendon ectopic calcification is detected. The invention finds and proves that the procyanidin SA hydrogel can effectively inhibit tendon ectopic calcification. Meanwhile, the administration route of sustained-release administration can reduce corresponding side effects generated by systemic administration while improving the local drug concentration, and has a clinical application prospect.
Owner:ZHEJIANG UNIV

Preparing method of calcium nutrient supplement

The invention discloses a preparing method of a calcium nutrient supplement, and belongs to the field of biochemical engineering and food additives. The method includes the steps of hydrolyzing caseinas the raw material through trypsin to obtain casein phosphoeptide, making the casein phosphoeptide react with octacosanol and calcium phosphate under the effect of acid phosphatase, and conducting phosphate esterification to form the calcium nutrient supplement (casein phosphoeptide-octacosanol ester-calcium phosphate CPP-OOL-ACP). The prepared calcium nutrient supplement (CPP-OOL-ACP) has the calcium content of 0.7% or above and the casein phosphoeptide and calcium chelating rate of 96%, is solid-state light yellow powder at normal temperature, is odorless, can be dissolved in water, and can effectively promote the calcium absorption and calcium deposition in bones, improve the bone density and increase the bone strength.
Owner:NANTONG UNIVERSITY

High-calcium emulsion for pet joint repair and preparation method thereof

The invention discloses a high-calcium emulsion for pet joint repair and a preparation method thereof; the high-calcium emulsion consists of the following components in parts by mass: 6-8 parts of xanthan gum, 7-9 parts of guar gum, 2-4 parts of diglycerin fatty acid ester, 2-4 parts of glucosamine hydrochloride, 5-7 parts of calcium phosphate, 4-6 parts of vitamin E, 6-10 parts of glucose, 7-9 parts of sodium carboxymethyl cellulose, 3-5 parts of chondroitin sulfate, 4-6 parts of vitamin A, and 3-5 parts of carrageenan. According to the medical theory formula, the high-calcium emulsion is prepared according to a certain weight ratio and by applying a scientific production process; while efficiently supplementing calcium for pets, the high-calcium emulsion also can promote calcium deposition in bones, protects health of cartilages and a bone matrix, and can more effectively repair the pet joints and increase the bone density.
Owner:杨箭

Biochemical composite material as well as preparation method and application thereof

PendingCN114107090AFacilitate depositionHigh urease production capacityBacteriaHydrolasesBacteroides speciesReproduction
The invention relates to the technical crossing field of microorganisms and environmental engineering, and particularly discloses a biochemical composite material as well as a preparation method and application thereof. Wherein the biochemical composite material comprises a urease-producing strain and a sustainable material carrier, the urease-producing strain is preserved in Guangdong Microbial Culture Collection Center on March 15, 2021, and the preservation number is GDMCC NO: 61559. According to the invention, urease-producing strains capable of promoting microorganism-induced calcium carbonate deposition are screened out; the biochemical composite material disclosed by the invention has the advantages of high urease production capacity, optimal bacterial reproduction capacity and high resistance to a heavy metal environment, and is beneficial to repairing heavy metal polluted soil; the corncob powder is adopted as a continuous material carrier, the cost is low, and the corncob powder serving as the carrier has an extremely high promoting effect on enrichment of urease-producing strains in soil and calcium deposition induced by the strains.
Owner:GUANGDONG TECHNION ISRAEL INST OF TECH
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