276 results about "Kidney stone" patented technology

The device to remove kidney stones is a medical retrieval basket device adapted to provide irrigation and suction to the region of the basket. The device includes a retrieval basket assembly having a sheath, an elongated member extending through the sheath, and a basket assembly coupled to the distal end of the elongated member, in a generally known arrangement. The retrieval basket assembly extends from a handle which provides suction and irrigation to, and through, the retrieval basket assembly. Fittings on the handle connect fluid and suction sources through fluid conduits within the handle to the sheath of the retrieval basket assembly. In one embodiment, the retrieval basket assembly's sheath has an expandable distal end portion that improves the retrieval basket assembly's ability to capture debris from lithotripsy of a stone.

Disclosed herein are embodiments of an electrosurgical device that include one or more floating electrodes and are specifically adapted to remove, cut, resect, ablate, vaporize, denaturize, drill, coagulate and form lesions in soft tissues, with or without externally supplied liquids, preferably in combination with a resectoscope, particularly in the context of urological, gynecological, laparoscopic, arthroscopic, and ENT procedures. Specific adaptations for urological and gynecological applications, for example kidney stone removal and BPH treatment, are also described.

A method of using a suction device to remove an object from a subject's body includes extending a suction device into the body through a lumen of a medical device and expanding the suction head from a contracted configuration to an expanded configuration within the body. The suction head may be provided at a distal end of an elongate conduit. The method may also include applying suction to move the object into the expanded suction head, and removing the suction device with the object from the body.

One aspect of the present invention relates to a method of using peristalsis to force a polymer plug through a mammalian lumen, thereby removing any calculi and / or calculi fragments present in the lumen. In one embodiment, the method is used as an alternative to conventional lithotripsy. In another embodiment, the method is used in conjunction with lithotripsy, thereby removing the small calculi fragments that result from such procedures.

The present invention relates to a method and apparatus for laser-based surgery and treatment, in particular of the human body. Inter alia, the present disclosure teaches an apparatus having a femtosecond laser that emits at least one pulse of laser energy having a pulse duration of less than 100 femtoseconds and a fiber optical channel for conducting said emitted pulse of laser energy to a vicinity of a human body to irradiate a localized area of said human body to effect at least one of microsurgery, neurosurgery, treatment of cardiovascular disease, treatment of the skin, tissue removal for biopsy, cutting of a mucous membrane, disintegration or vaporization of a gallstone or a kidney stone, and orthopedic surgery.

A stone removal system comprises a sweeping structure and a dilating structure. The sweeping structure is deployed on a kidney side of a urinary stone in the ureter. Should the sweeping structure be unable to remove the kidney stone, the dilating structure is placed on the bladder side of the kidney stone and used to dilate the lumen of the ureter. The dilated lumen allows the sweeping structure to more easily remove the kidney stone. Should the kidney stone still resist removal, a lithotripsy device may be introduced through the ureter and energy directed through openings in the dilation structure to fragment the stone.

The present disclosure is directed to a medical device. Systems and methods are provided for utilizing a laser to break a kidney stones into smaller fragments and / or dust, and removing particles, stone fragments and / or stone dust from a patient. The medical device may include a tube having a distal end and a proximal end, a first lumen extending from the proximal end to the distal end of the tube and in fluid communication with the distal end and a plurality of side ports located at a distal portion of the tube, and a second lumen extending from the proximal end to the distal end of the tube.

The invention relates to Febuxostat and a drug combination thereof, wherein the Febuxostat is Febuxostat crystal, belonging to monoclinic system, the space group of the crystal is P2 (1), and cell parameters comprise a=4.7179 (9), b=17.813 (4), c=10.690 (2), alpha=gamma=90 degrees, and beta=99.20 (3) degrees; and the cell volume is 886.8(3) <3>. In addition, the invention also relates to a drug composition containing the Febuxostat crystal and a preparation method of the crystal, and simultaneously the invention further discloses application of the Febuxostat crystal in treating hyperuricemia comprising primary and secondary hyperuricemia, acute and chronic gout, gouty arthritis, gouty nephropathy and renal calculus which are caused by the hyperuricemia.

Devices, systems, and methods are provided for breaking a kidney stone(s) into smaller particles, fragments, and / or stone dust; and removing the same from a patient. The medical device may include a tube having a distal end, a proximal end, a port located proximal of the distal end, and a length of the tube extending between the proximal end and the distal end. A first portion of the tube may be proximal of the port and have a first cross-sectional area, while a second portion of the tube may be distal of the port and have a second cross-sectional area smaller than the first cross-sectional area. A first lumen may extend from the proximal end to the distal end of the tube. A second lumen may in communication with the port to fluidly connect the proximal end of the tube with the port.

The invention discloses a tactile interaction-based percutaneous nephrolithotomy (PCNL) kidney stone virtual surgical training system and a method for improving the repeated training of urologists soas to make the urologists obtain puncture skills. The system specifically includes a medical image three-dimensional reconstruction module (1), a kidney soft tissue sample puncture experiment module (2), a mechanical modeling module (3), a visual rendering module (4), a tactile rendering module (5), a virtual operation training environment design module (6), a tactile interaction device module (7), an operation training data acquisition and analysis module (8), an augmented reality module (9) and a 3D printing module (10). According to the system of the present invention, a real surgical trocar is adopted to puncture a kidney tissue, so that data can be obtained to be used for establishing a mechanical model; the system enables a strong sense of immersion and high real-time performance onthe basis of a virtual PCNL operation environment constructed through the tactile interaction device, the augmented reality technology and the 3D printing technology. With the system adopted, the training of the urologists can be facilitated, the operative skills of the urologists can be improved, and the urologists can be familiar with the procedures of an operation.

The invention relates to a drug for treating purine metabolic disorder disease, provides a flavonoids compound represented by the formula (I) and a modified derivative thereof, and a use in inhibition of xanthine oxidase activity and promotion of uric acid excretion function, wherein R1, R2 and R3 independently represent -H or monosaccharide residues, and R4 represents -H or -OH. In particular, the drug is used for treating purine metabolic disorder disease, and can be used for treating hyperuricemia and related diseases and reducing a individual serum UA level; the drug is used for treating hyperuricemia; the drug is used for treating the related diseases, such as for treating gouty arthritis and arthrophlogosis caused by hyperuricemia, and for treating chronic interstitial nephritis, kidney stones and the like caused by hyperuricemia. The drug has the advantages of natural chemical structure, safety, low toxicity, rapid curative effect and fewer side effects. (I).

The present invention relates to identifying the risk of a subject developing renal stones utilizing an assessment of PTH agonist, antagonist and / or total PTH levels, optionally together with an assessment of serum and / or urine calcium levels and / or other analytes. The present description further relates to monitoring and guiding treatment for renal stones and kits useful therefore.

The invention discloses a liftable kidney stone treatment apparatus with a support device in the technical field of medical equipment, comprising a movable plank bed, a pillow is arranged on the top of the movable plank bed, and a fixed plank bed is arranged at the right end of the movable plank bed. The movable plank bed and the fixed plank bed are connected by hinges, the top of the fixed plank bed is provided with a support device, the top of the support device is provided with a sliding support frame, the front and rear side walls of the fixed plank bed are provided with chute, the sliding support The bottom inner wall of the frame is provided with a sliding block matched with the chute. In the present invention, a movable plank bed, a limit block, a lifting screw, a rotating screw and a manual crank are arranged, and the rotating screw is driven to rotate by the manual crank, and the rotating screw and the lifting The screw is matched to make the lifting screw move up and down, and the lifting screw drives the angle adjustment of the movable plank, which is convenient for the patient to get up and down.

A method of preventing or inhibiting L-cystine crystallization using the compounds of formula I is disclosed.R1a—O-(-A-L-)m-A-O—R1b  I,wherein A, L, R1a, R1b, and m are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to L-cystine crystallization, such as comprising (but not limited to) kidney stones.

The invention discloses a Chines medicine composition preparation capable of curing renal calculus. The Chines medicine composition preparation capable of curing the renal calculus is mainly composed of fringed pink, spora lygodii, poria cocos, rhizoma alismatis, grifola, longhairy antenoron herb, plantain seeds, radix cyathulae, myrrh and qizzard pepsin. The Chines medicine composition preparation capable of curing the renal calculus has effects of diuresis inducing and strangurtia treating, has good treatment effects of pain, dark urine, dysuresia caused by the renal calculus and capable of effectively and fast curing the renal calculus. The Chines medicine composition preparation capable of curing the renal calculus is ideal and safe medicine capable of curing the renal calculus.

The invention relates to a determination reagent against bilirubin interference based on a uricase method and an application method thereof. The reagent is a liquid double-reagent and has good resistance against bilirubin interference and excellent stability. The reagent can be used in a semi / full-automatic biochemical analyzer by adopting a two-point end assay method. By adopting a specific enzyme, the reagent has the characteristics of high sensitivity and strong anti-interference capability; and by adding a selected stabilizing agent, the reagent achieves good stability, namely, the reagent can be hermetically preserved at the temperature of 2-8 DGE C in dark place for 12 months without causing performance deterioration. The reagent can be widely applied to diagnosis, of kidney diseases such as acute and chronic nephritis, kidney stone, gout and the like as well as diseases resulting from excessive nucleic acid metabolism, such as leukemia, multiple myeloma and the like, physical examination and general investigation of kidney diseases and the like.

The invention relates to a traditional Chinese medicine for treating kidney stone. The traditional Chinese medicine for treating the kidney stone consists of 15 g of climbing fern, 35 g of loosestrife, 15 g of gizzard pepsin, 15 g of talcum powder and 5 g of liquoric root, wherein the accuracy of the proportion of the medicines is + / -5 percent. A use method of the traditional Chinese medicine comprises the following steps of: mixing the medicines together; placing in a medicine pot; placing in 1,000 g of clear water to soak for 1 hour; boiling with intense fire; slowly decocting with slow fire until 400 g of water is remained; and taking after the medicine is at normal temperature, a dose each day. The traditional Chinese medicine is taken in one hour after dinner each day, seven doses are continuously taken for a period of treatment, and another seven doses are taken after three days, so that the kidney stone can be cured. According to the traditional Chinese medicine for treating the kidney stone, clinical use proves that not only the symptom of a patient can be relieved during taking after one to three periods of treatment are used, but also the kidney stone can be completely cured after the traditional Chinese medicine is taken; and the traditional Chinese medicine has a particularly obvious effect and no toxic or side effect and is low in cost.

A method for producing pear residue dietary fiber biscuits includes the specific steps that firstly, butter is softened and beaten at room temperature; secondly, flour is mixed with the mixture evenly; thirdly, dough is prepared; fourthly, the dough is fermented; fifthly, the dough is pressed by means of a mould; sixthly, baking is conducted; seventhly, cooling and packaging are carried out. The pear residue dietary fiber biscuits are beneficial to gastro-intestinal digestion, and have the advantages of regulating intestinal balance, improving intestinal flora, keeping human intestinal tract circulation smooth, clearing away toxin and relaxing the bowels, reducing diabetes, improving human immunity, reducing kidney calculi and preventing cardiovascular diseases, diabetes and hypertension. Compared with traditional biscuits, the pear residue dietary fiber biscuits have the advantages of being low in grease, sugar and calorie. The practical manufacturing method of the pear residue dietary fiber biscuits is provided for utilization of residues generated in juice production, maximum resource utilization is achieved, and the function of saving resources is achieved. The biscuits have good health-care functions, market prospects and popularization value.

The present invention relates to an apparatus for using the hydrodynamic cavitation in medical treatment such as destroying kidney stones or killing infected cancer cells. This apparatus comprising a tank used as a container for a fluid,a compressor which is connected to the tank in order to maintain the input pressure of the fluid, a tubing in which the fluid flows,a probe in which the cavitation occurs,a valve, which is positioned inside the tubing, allowing the fluid to flow into the probe,a filter, which is positioned inside the tubing, preventing the predetermined size particles flow into the probe,a fitting connecting the probe to the tubing, a flowmeter measuring the volume flow rate of the fluid through the probe,an image capturing unit capturing the sequential images of bubble growing and collapsing of the bubbles after the bubbles exit from the probe,a positioning assembly which adjusts the distance between the probe and the target surface and a control and data acquisition unit.

The invention relates to an instant oral liquid for kidney stone, comprising the following medicine materials in portions by weight: 3-10 portions of cinnamon, 6-15 portions of white atractylodes rhizome, 6-15 portions of grifola, 6-30 portions of poria cocos, 6-15 portions of oriental waterplantain rhizome, 20-60 portions of longhairy antenoron herb, 6-15 portions of lygodium japonicum and 6-15 portions of cluster mallow fruit. The instant oral liquid for kidney stone is also characterized by comprising the following medicine materials in portions by weight: 3-30 portions of plaster stone, 6-15 portions of rhizoma anemarrhenae, 5-10 portions of fructus forsythiae, 6-12 portions of ginseng, 15-60 portions of astragalus mongholicus, 10-30 portions of cornus officinalis, 15-30 portions of rehmanniae praeparatum and 5-10 portions of radix glycyrrhizae. The dosage of herbal medicines in the formulation is increased by 1,000 times, about 800L of water is added to decoct about 160L of the liquid, and the plaster stones are ground into fine powder to evenly mix into a decocting liquid so as to package into 100ml for each bottle. The invention has the advantages that the traditional Chinese medicine for clearing heat, promoting diuresis and eliminating urolith is added on the basis of clearing fire away and tonifying yin and qi with the favorable treatment effect, 300 cases of urinarystone are clinically treated in the clinical experiment with 100 percent of the cure rate, and patients have no obvious pain in the process of urolith elimination.

The invention discloses a pharmaceutical composition for treating kidney stone. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 16-24 parts of gravel grass, 5-13 parts of lysimachia christinae hance, 5-13 parts of plantain herb, 5-13 parts of endothelium corneum gigeriae galli, 5-13 parts of dianthus superbus and 5-13 parts of pyrrosia lingua as active components. The defects of the existing drug for treating the kidney stone are overcome, and pharmaceutical composition with a good treatment effect on the kidney stone is provided.

The invention provides application of N6-(2-ethoxy)adenosine in preparation of preparations for treating renal failure. By virtue of the N6-(2-ethoxy) adenosine, levels of inosine and urea nitrogen in renal failure and renal ischemia reperfusion injury can be obviously reduced, and renal tubular epithelial cell apoptosis and kidney inflammations are inhibited. The N6-(2-ethoxy) adenosine can be applied to multiple treatment applications of renal failure, renal transplant, renal ischemia reperfusion injury, kidney stone lithotripsy inflammations and other nephritides.

In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting / preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.

The invention relates to lemon flavored nutritional bean curd (tofu) and a preparation method thereof. The lemon flavored nutritional tofu comprises soybean milk and lemon juice, wherein the weight ratio of the lemon juice and the soybean milk is (1-3):100, and is prepared by the steps of carefully selecting raw materials, pulping, boiling pulp, adding lemon juice, compression moulding, and othersteps. The lemon flavored nutritional tofu has the color and fragrance of lemon, rich nutrient and tender mouthfeel. The preparation method of the lemon flavored nutritional tofu uses fresh lemons directly without addition of other coagulators, only uses the action of lemon self to achieve the coagulating effect of tofu, so as to simplify preparation process, prevents environmental pollution and fully utilize raw materials. The obtained tofu has the fragrance and nutritional ingredients of lemon. The preparation method of the invention does not use calcium salts and magnesium salts, and citrate contained in the lemon juice can inhibit calcium salts crystallization, thereby preventing the formation of renal calculi, even dissolving the calculi formed previously. The lemon flavored nutritional tofu of the invention is suitable for a large range of people.

The invention belongs to the technical field of medicines, and relates to a medicine composition for treating liver and gall calculus or kidney stone. In order to make up the defects of the prior art and relieve the pain of patients with liver and gall calculus, the invention provides the medicine composition for treating liver and gall calculus or kidney stone. The curative medicine has remarkable analgesic activity and stone dissolving and discharge functions, is remarkable in curative effect, is safe and reliable, and has a wide clinical application prospect.

The invention discloses a calculus enzyme which is an enzyme capable of defusing calculus. The calculus enzyme can be applied to a human body as food, beverage, health-care products, drugs or injection to prevent and defuse body stones. The calculus enzyme is convenient to use, mild in reaction, and free of toxic and side effects, and can prevent and treat renal calculus, urinary stones, gastric concretion, gall-stones and the like inside the human body. Clinical practices prove that the stones with different sizes inside the human body can be mildly defused and removed without crushing the stones. The preparation method of the calculus enzyme comprises the following steps: adopting the following raw materials in parts by weight: 20-30 parts of carbon source, 1-10 parts of nitrogen source and 40-94 parts of water, and 1-10 parts of nutritive salt and 1-5 parts of auxin serving auxiliaries; inducing microorganisms to ferment, culture, digest, separate and concentrate, so as to obtain a liquid crude product by adopting an artificial ox-gall calculi or body stones by a solid fermentation method; carrying out spray drying to obtain a solid crude product; filtering and refining the liquid crude product, so as to obtain a liquid refined product; separating, settling, centrifuging, and freeze-drying the liquid refined product, so as to obtain a lyophilized product, namely a solid refined product.

The present invention relates to compounds which are inhibitors of sodium dependent glucose co-transporter-2 (SGLT-2). These compounds are used in the treatment of various disorders, including diabetes, impaired glucose tolerance, insulin resistance, retinopathy, nephropathy, neuropathy, cataracts, hyperglycemia, hyperinsulinemia, hyperchlolesterolemia, elevated blood level of free fatty acids or glycerol, hyperlipidemia, hypertriglyceridemia, obesity, wound healing, tissue ischemia, atherosclerosis, and hypertension. These compounds and compositions are also useful for treating and preventing kidney stones, hyperuricemia, gout, and hyponatremia. Methods of making these compounds are also described in the present invention.