The invention discloses a bone tonifying pill. The bone tonifying pill comprises barn lantern grass, caulis spatholobi, roots of twisting dregea, pseudo-ginseng, eucommia ulmoides, frustus psoraleae, herba epimedii, field dodder, morinda officinalis, Philippine flemingia root, angelica sinensis, ginseng, blood circulation invigorating trees, centella asiatica, saffron crocus, corn cervi pantotrichum, agkistrodon acutus, centipedes, whole scorpions, olibum and myrrh, lumbricus, leeches, herba cistanches, rehmannia glutinosa, dipsacus roots, herba taxilli, rhizoma corydalis, collected bone, pure honey and malt sugar. The invention further discloses a preparing method of the bone tonifying pill. The pure honey and the malt sugar are added after other components are concentrated, and then the pill is refined. The bone tonifying pill is taken orally and used for treating the symptoms of shoulder portion scleromere inflammation pain, osteoproliferation, bone and joint rarefaction and degeneration, intervertebral disc calcification extrusion, rheumatoid sore pain, limb sore and numbness, woman laying-in cold, acute and chronic gout, ischiadic nerve pain, injuries from falls, fractures, contusions and strains and the like. The bone tonifying pill is obvious in effect and wide in application range. The preparing method of the bone tonifying pill is simple, and the prepared bone tonifying pill is obvious in effect.