489results about How to "Improve kidney function" patented technology

Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.

Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.

Methods and apparatus are provided for treating congestive heart failure using a catheter having an inlet end configured for placement in the source of arterial blood such as the aorta, left ventricle or a femoral artery, and an outlet end having at least one conduit configured to be placed in the renal arteries. The catheter includes a lumen through which blood passes from the aorta or left ventricle directly to the renal artery, means for engaging the first conduit with renal artery. The means for engaging also may reduce backflow of blood into the abdominal aorta. The catheter preferably is configured to permit percutaneous, transluminal implantation. Methods of using and implanting the catheter are also provided.

In one aspect, the present invention is directed to an apparatus and method for treating congestive heart failure that restores kidney renal functions by artificial perfusion of at least one kidney. In one aspect, a catheter inserted into the aorta of the patient has an outlet port that supplies the patient's blood obtained from a patient's aorta into an adjoining renal artery of the patient to perfuse the kidney. The catheter comprises a rotor housed inside a portion of the catheter to supply the blood to the kidney at a desired pressure. The restoration of kidney function assists the heart by removing excess fluid, urine and toxin from the patient, and by normalizing the patient's renin-angiotensin system and other neurohormonal substances.

Apparatus, systems, and methods in which a catheter-based pump is used are disclosed. The catheter-based pump is placed within the inferior vena cava of a patient. The catheter-based pump has a variable obstructor, such as a balloon or some other artificial obstruction, which is sized and dimensioned to compartmentalize the inferior vena cava into an upstream region and a downstream region of the inferior vena cava. The catheter-based pump is configured to pump blood from the upstream region to a fluid line that discharges blood to a discharge location in the downstream region. Thus, a suitable pressure gradient across the organ is provided, which can benefit organ function.

The invention relates to multi-grain nutrition and health hot drink. The hot drink comprises a proper amount of soybean meal, black bean meal, black rice flour, red bean flour, corn flour, semen coicis flour, coarse rice powder, small yellow rice (millet) flour, buckwheat, aromatic glutinous rice flour, oat powder, black sesame seed powder, walnut powder, peanut powder, purple sweet potato powder, yam flour, jujube powder, wolfberry powder, longan powder, black fungus powder, oligosaccharides, vegetable fat powder and iodine-free salt. The multi-grain nutrition and health hot drink disclosed by the invention contains twenty natural grains, natural vegetable fat crops and functional health plants which are taken as raw materials, has three effects of comprehensive nutrition, natural fragrance and functional health and is a safe, healthy and functional health food with the advantages of natural fragrance, natural nutrition, comprehensive health and pleasant diet.

This document provides methods and materials related to PDE V inhibitors, natriuretic polypeptides, and combinations thereof. For example, compositions containing one or more PDE V inhibitors in combination with one or more natriuretic polypeptides are provided herein. In addition, methods for using PDE V inhibitors, natriuretic polypeptides, and combinations thereof to influence heart or renal activities within a mammal are provided herein.

Devices and methods are provided to treat acute and chronic heart failure by using one or more implantable or non-implantable sensors along with phrenic nerve stimulation to reduce intrathoracic pressure and thereby reduce pulmonary artery, atrial, and ventricular pressures leading to reduced complications and hospitalization.

A system for delivering a renal treatment and a peripheral treatment includes a renal catheter, a peripheral catheter, and an introducer sheath having first and second lumens. The first lumen is configured to receive the renal catheter and is sized to extend from a patient insertion site to a femoral or iliac artery location near or distal to a patient aortic branch. The second lumen is configured to receive the peripheral catheter and is sized to extend from the patient insertion site to an opposite femoral or iliac artery location near or distal to the patient aortic branch. A method of delivering a renal treatment and a peripheral treatment includes positioning an introducer sheath in an iliac artery, advancing a renal catheter and a peripheral catheter through the introducer sheath, where the renal catheter is separated from the peripheral catheter within the introducer sheath by a flap.

The present invention provides methods of treatment of patients suffering from the complications of blood sugar disorders: diabetic peripheral neuropathy and diabetic nephropathy by administration of IGF-1 via protein therapy or gene therapy. It relates to methods of treating an individual having a diabetic disorder or a hyperglycemic disorder, comprising administering to the individual an effective amount of a DNA vector expressing IGF-1Eb or IGF-1Ec in vivo or an effective amount of at the IGF-1Eb or IGF-1Ec protein in the early hyperalgesia stage or in patients that have advanced to the hyposensitivity stage. Treatment at the early hyperalgesia stage prevents subsequent hyposensitivity with increases or maintenance of sensory nerve function. IGF-1Eb or IGF-1Ec treatment also increases muscle mass and improves overall mobility, which indicates a treatment-related improvement in motor function. Treatment with IGF-1Eb or IGF-1Ec at the hyposensitivity stage reverses hyposensitivity and improves muscle mass and overall health. Systemic IGF-1 provides a therapeutic modality for treating hyposensitivity associated with DPN. In addition, IGF-1Eb or IGF-1Ec provides a therapeutic modality for treating diabetic nephropathy. IGF-1Eb or IGF-1Ec improves renal function as evidenced by a modulation in serum albumin concentration and a reduction in urine volume and protein levels. IGF-1Eb or IGF-1Ec also reduces diabetic glomerulosclerosis.

This document provides methods and materials related to PDE V inhibitors, natriuretic polypeptides, and combinations thereof. For example, compositions containing one or more PDE V inhibitors in combination with one or more natriuretic polypeptides are provided herein. In addition, methods for using PDE V inhibitors, natriuretic polypeptides, and combinations thereof to influence heart or renal activities within a mammal are provided herein.

The invention relates to methods for improving renal (kidney) function. Methods for decreasing blood urea nitrogen (BUN), for increasing glomerular filtration rate (GFR), and for decreasing serum creatinine are also provided.

The invention belongs to the technical field of microbial fermentation, and in particular relates to a liquid fermentation method for producing paecilomyces cicadae mycelia and application of a culture product. The method comprises the following steps of: preparing a culture medium, preparing culture solution, filling the culture solution in a fermentation tank, sterilizing, cooling, inoculating, and performing aerated fermentation. By the culture method, a large number of paecilomyces cicadae mycelia and conidia can be generated, and the culture product has the effects of resisting tumors, regulating immunity, reducing blood sugar, blood fat and blood pressure, improving eyesight, resisting radiation, relieving heat and pain, calming and hypnotizing, nourishing and strengthening, improving the renal function and the like, and can be applied to foods, health care products, medicines, cosmetics and the like. The liquid fermentation production process is short in period, high in yield, environment-friendly, stable in product quality and suitable for mass production.

The present invention relates to one kind of plant leavening prepared by using plant with hot and fragrant smell of propylene sulfide, yeast and lactobacillus and through fermentation. The present invention also relates to the preparation process of the leavening and its application is treating presbyopia, cataract and other diseases, promoting blood circulation; improving the functions of sexual organs, kidney, cardiac and cerebral vascular system, digestive system, etc.; resisting oxidation, senility and fatigue; lowering blood fat, blood sugar and blood pressure; etc.

The invention relates to methods for improving renal (kidney) function. Methods for decreasing blood urea nitrogen (BUN), for increasing glomerular filtration rate (GFR), and for decreasing serum creatinine are also provided.

The invention provides a composition containing two or more extractives extracted from all or part of hibiscus manihot flower, seed powder, seed oil, hibiscus manihot root, hibiscus manihot leaf and hibiscus manihot stem, a preparation method thereof, a product containing the composition and a usage thereof. The product of the invention adopts biological raw materials, which has excellent efficacies of eliminating dampness and heat, diminishing inflammation, detoxification, relieving pain, enhancing human immunity, enhancing physical fitness, lowering blood lipid, lowering blood pressure, improving microcirculation, improving organic antioxidant capacity, regulating kidney function, promoting human health and having no toxicity and side effects.

The invention relates to a weight reducing and fat reducing special type clinic nutrition recipe, which comprises 20 to 38 parts of protein, 8 to 12 parts of fat, 40 to 50 parts of carbohydrate, 5 to 8 parts of dietary fiber, 0.3 to 1.5 parts of macro elements, 0.01 to 0.04 part of trace elements, 0.005 to 0.015 part of lipid-soluble vitamin, 0.01 to 0.3 part of water-soluble vitamin, 0.05 to 1 part of dietary essence, 0.1 to 2 parts of medical and edible ingredients, 0.1 to 3 parts of natural plant compounds and 0.005 to 2 parts of new resource food, wherein the medical and edible ingredients are selected from at least one of poria cocos, fructus lycii, lotus leaves, semen cassiae, radix platycodi, rhizoma dioscoreae, fructus crataegi and coix seeds; each ingredient is prepared into powder in advance; the fat and the vitamin are prepared into powder by using a micro-capsule embedding technology. Through the screening and the proportioning of the ingredients, the nutrition recipe provides reasonable and overall nutrition support for patients with adiposity; meanwhile, the medical and edible ingredients, the natural plant compounds and the new resource food with the effects of replenishing qi to invigorate the spleen, eliminating phlegm, removing dampness and reducing weight and fat are added, so that the effects of preventing and treating the adiposity are achieved.

The disclosure provides methods for treating, preventing, and reducing risk of occurrence of renal insufficiency in mammals. The disclosed methods include administering to a subject susceptible to, or afflicted with, renal disorder therapeutically effective amounts of a TGF-β antagonist and a renin-angiotensin-aldosterone system (RAAS) antagonist so as to maintain desirable levels of renal function. The populations treated by the methods of the invention include but are not limited to patients suffering or at risk for the development of renal insufficiency, such as those afflicted with type I or type II diabetes, hypertension, (auto)immune disease, systemic fibrosis, etc.

The invention provides compositions for preventing or treating kidney disease and improving kidney function comprising at least two ingredients selected from the group consisting of antioxidants and mitochondrial cofactors in amounts sufficient for preventing or treating kidney disease or for improving kidney function and methods for preventing and treating kidney disease or improving kidney function comprising administering such compositions to an animal susceptible to or suffering from kidney disease or impaired kidney function. In a preferred embodiment, the composition is admixed with one or more food ingredients to produce a food composition useful for preventing or treating kidney disease and improving kidney function, particularly in senior animals.

The invention discloses a radix scutellariae total flavonoids aglycon extract, also a preparation method of radix scutellariae total flavonoids aglycon extract and functions of treating and resisting renal fibrosis. Content of total flavonoids aglycons in the radix scutellariae total flavonoids aglycon extract is 45-70%. The extract is mainly composed of scutellarein, wogonin, oroxylin A and other aglycons. The preparation method of the extract is as follows: crushing radix scutellariae roots, screening by a No. 1 screen; adding 1-5 times amount of water, uniformly stirring, keeping temperature for enzymolysis at 32-40 DEG C for 5-9 hours, baking under vacuum at 60 DEG C, adding 2-8 times amount of ethyl acetate, continuously extracting for 6-10 hours, depressurizing, recycling solvent, thus obtaining total flavonoids aglycon extract. The extract can obviously relieve renal fibrosis symptoms when irrigated into a mouse stomach with renal fibrosis caused by mercuric chloride moulding and when a group of mice having the extract is compared with group of mice without having the extract. Results suggest that the total flavonoids aglycon extract has a dose dependence in preventing renal fibrosis.

The invention discloses a blood sugar reducing and lipid regulating healthcare nutrious tea and its production method; the tea is produced by 10-80 parts of green tea, 2-60 parts of lychee seeds, 2-60 parts of polygonum cuspidatum, 1-40 parts of cortex lycii radicis, 1-40 parts of corn silk, 1-30 parts of Alisma orientale, 1-30 parts of Astragalus root, 1-30 parts of atractylodes rhizome and 1-20 parts of ginseng; the green tea is used as the substrate, evenly absorbing the liquid extract of the other eight kinds of traditional Chinese medicine plants. The tea has good blood sugar reducing, lipid regulating and healthcare functions and has no adverse reaction; the tea is suitable for patients with diabetes and metabolic syndrome, doing good to improve the symptom and prevent complication; the tea is good at removing free radical anti-oxidation damage, and has healthcare functions of blood sugar reduction and lipid regulation, atherosclerosis prevention, blood pressure regulation, weight reduction, liver and kidney protection, immunity improvement and so on.

The invention provides a clinical nutritional formula special for kidney dialysis. The clinical nutritional formula special for kidney dialysis comprises the following components in parts by weight: 15-25 parts of protein, 8-12 parts of fat, 50-54 parts of carbohydrate, 3-5 parts of dietary fiber, 0.3-0.6 part of macro-elements, 0.01-0.05 part of trace elements, 0.005-0.02 part of fat-soluble vitamin, 0.01-0.2 part of water-soluble vitamin, 0.05-1 part of dietary essence, 0.05-2 parts of medicinal and edible components, 0.1-3 parts of natural plant compounds, and 0.005-2 parts of new resourcefood; and the invention also provides a preparation method of the clinical nutritional formula. The clinical nutritional formula special for kidney dialysis provided by the invention can provide balanced nutrient substances for patients with renal dialysis, and can maintain the stability of the body quality of the patient, enhance the ability of immune response and the repair function, reduce inflammation, and improve the activity of scavenging oxygen free radicals and the endothelial cell function.

A medicine pot food made with the tuber of multiflower knotweed and black hens is prepared by boiling black hen or family fed hen with twelve kinds of chinese medicines in the pot and then adding theflavorings prepared in rice wine with 16 Chinese medicines. To keep eating the invented medicine food helps the people in good health, especially good for those who are after radia therapy and chemotherapy as well as delivery woman and their postpartum.

The present invention discloses a medicine composition for treating osteoporosis, which contains soybean isoflavone, nano pearl powder and vitamin D3 as main components and can contains the Chinese medicine components of ophiopogon root, wolfberry fruit, privet fruit, tortoise plastron, turtle shell, etc. The medicine composition of the present invention has high calcium replenishing effect and complete functions. It can raise the bone density obviously and has also the health functions of postponing women's climacteric, improving kidney function, etc. It has no toxic side effect, and is suitable for middle aged and old people, especially women of 40-65.

The invention belongs to the technical field of microbial fermentation, and specifically relates to media for producing Paecilomyces cicadae conidiospores, a culture method thereof, a culture product thereof and application thereof. The media for producing Paecilomyces cicadae conidiospores comprise a solid medium and a liquid medium. The culture method provided in the invention can produce considerable Paecilomyces cicadae conidiospores; the culture product of the method comprises components like polysaccharides, cordycepic acid, adenosine, triterpenoids and a plurality of amino acids, has the functions of regulating immunity, relieving fever and pain, improving renal function, lowering blood pressure, resisting radiation and tumor, reducing blood sugar, etc., and is applicable to the field of human healthy life; considerable spores are generated in the process of fermentation and the generated spores can be used as effective means of biological control, thereby solving the problem that the amount pesticide residues in agricultural products exceed the standard amount from the head stream.

The invention discloses healthcare food capable of improving cardiovascular and cerebrovascular circulation systems, increasing the release of NO in vascular endothelial cells and enhancing the anoxia resistance of the organism, a preparation method thereof and application of the healthcare food in preventing cardiovascular and cerebrovascular diseases and improving the anoxia resistance of the organism. The healthcare food disclosed by the invention is prepared from the following raw materials in parts by weight: 1-6 parts of American ginseng, 8-16 parts of radix salviae miltiorrhizae and 1-5 parts of panax pseudoginseng. The preparation method of the healthcare food disclosed by the invention completely extracts the active ingredients of radix salviae miltiorrhizae; and meanwhile, by adopting a micronization technology for the panax pseudoginseng and radix salviae miltiorrhizae, the surface area of the healthcare food is increased, the absorbance is improved, and the damage to the active ingredients of the panax pseudoginseng and radix salviae miltiorrhizae in the extraction process is reduced so as to improve the healthcare effect.

The medicine for treating uaemia and kidney-Yang deficiency and kidney exhaustion is prepared with astragalus root, Chuanxiong rhizome, red sage and rhubarb in certain proportion. The medicine has the functions of warming and invigorating spleen and kidney, promoting blood circulation to disperse blood clots, and eliminating wetness and expelling turbid substance, so that it has high curative effect and no toxic side effect.

A health-care medicinal pillow is composed of pillow case and internal bag containing Chinese medicine prepared from 34 Chinese-medicinal materials including Chinese angelica root, Chuan-xiong, rhizome, safflower, chrysanthemum flower, etc.

The invention discloses a medicine for treating chronic renal failure and a preparation method thereof. The medicine for treating chronic renal failure comprises bulk pharmaceutical chemicals, namely rehmanniae praeparatum, fructus corni, Indian buead, astragali radix and rhizoma atractylodis macrocephalae which are proportionally processed and prepared into granules. The medicine for treating chronic renal failure provided by the invention has functions of replenishing qi, nourishing kidney, invigorating spleen, resolving stasis, detoxing and removing turbidity, and can be used for treating the diseases such as early-stage and middle-stage chronic renal failure, spleen and kidney deficiency of syndrome differentiation of chronic kidney disease, blood stasis and obstruction, toxin and turbidity accumulation and the like.

The invention relates to a Chinese herbal medicine additive used for improving breeding ram reproductive performance. The invention aims at solving problems of Cashmere goat breeding ram low ejaculation volume, insufficient sperm motility rate, insufficient sperm density, and the like caused by high semen collection frequency. The additive is prepared from the Chinese herbal medicines of, by weight, according to a total weight as a standard, 25% of epimedium, 12.5% ??of desertliving cistanche herb, 12.5% ??of dodder, 12.5% ??of medlar, 12.5% of medicinal morinda root, 12.5% ??of mongolian milkvetch root, and 12.5% ??of stir-fried malt. With the additive provided by the invention, functions such as ejaculation volume increasing, sperm density increasing, gonad protecting, sexuality strengthening, male hormone activating, reproductive function promoting, and physical health maintaining are provided for breeding rams.