110 results about "Blood urea nitrogen" patented technology

Optical sensor devices, image processing devices, methods and computer readable code computer-readable storage media for detecting biophysical parameters, chemical concentrations, chemical saturations, vital signs and physiological information such as a malignant condition are provided. In some embodiments, the optical sensor includes an array of photodetectors, where each photodetector is configured to detect a spectrum of light. In some embodiments, the image processing device receives a live still or video electronic image, or alternatively, the electronic image is provided from an electronic storage media. Exemplary physiological parameters include but are not limited to a pulse rate, a biophysical or physiological property of skin, a cardiovascular property, a property related to an organ such as the liver or the kidneys, and a temperature fluctuation. In some embodiments, the physiological parameter is indicative of a malady including but not limited to an autoimmune disease, a cancer, a nutritional deficiency, a malignant condition of bone marrow, a present of an infectious microbe such as a fungus, a present of hepatitis, and a cardiovascular disorder a pulmonary disorder. Exemplary chemical concentrations include but are not limited to a chemical saturation, a pH level, a pH level in blood vessels such as capillarys or in skin, a glucose level such as a blood glucose level, a urea nitrogen level such as a blood urea nitrogen level, a CO2 level such as a blood CO2 level or a CO2 saturation level, and an oxygen level such as a blood oxygen level or a blood oxygen saturation level. In some embodiments, the biophysical parameter, physiological parameter or chemical concentration is obtained from reflecting light from tissue from a mammalian subject. Alternatively one or more of these parameters are detected from a food item such as food tissue, a consumable beverage such as an alcoholic beverage, a dairy product, wine, a baked good, a fruit and a vegetable. Exemplary parameters related to food items include but are not limited to a parameter indicative of cooking or spoilage, a pH, a concentration of an antioxidant, and a concentration of an anti-inflammatory agent.

The invention discloses a preparation method for extracting flavone from purslane and application thereof. The medicine is characterized by a purslane alcohol extract. The preparation method comprises the following steps: 1. cleaning and drying the purslane; 2. cutting the purslane into short sticks; 3. extracting the flavone in the purslane by the reflux of alcohol; 4. performing the pumping filtration on the extracting solution; and 5. concentrating the liquid obtained after pumping filtration. The application method of the extract comprises the following steps: 1. inoculating tumor cells; 2. randomly dividing mice into four groups; 3. performing the group treatment; 4. sampling the blood, and weighing tumor; 5. obtaining blood serum; 6. measuring the content of blood urea nitrogen; and 7. measuring the content of serum creatinine. Animal tests prove that the extract can effectively resist kidney damage caused by the anticancer drug cisplatin; moreover, the extract has the advantages of convenient drug application, good effect and no toxic and side effects; and the purslane is wide in source, and low in price, so that the extract also has the advantages of low price and good quality.

Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to ameliorate renal failure (e.g., improved diuretic effect and / or lowering blood urea nitrogen, proteinuria, and / or serum creatinine levels) in a subject as a result of having been cultured in the presence of an alternating electric field having a specific frequency and a specific field strength. Also included are methods of making and using such compositions.

The invention belongs to the technical field of biology and particularly discloses selenium-rich bifidobacterium longum as well as a preparation method and application thereof. The selenium-rich bifidobacterium longum prepared by virtue of the preparation method can be applied to the preparation drugs or foods for delaying the progress of diabetes mellitus and particularly can be applied to the preparation of the drugs or the foods for improving the physical signs and metabolism conditions of diabetes mellitus, the insulin signal pathways of a diabetes mellitus model, the pathological change of livers, pancreas and kidneys of patients with diabetes mellitus and the levels of serum creatinine and blood urea nitrogen of diabetes mellitus and preventing renal complications or renal function damage of diabetes mellitus.

Kidney disease is diagnosed by measuring urinary catalytic iron in humans. Progressive kidney disease is treated by administering an iron chelator to humans. In particular, the progression of kidney disease essentially can be halted and the severity of kidney disease can be reduced by the administration of iron chelators to humans afflicted with a progressive kidney disease. The methods include measuring catalytic iron content in urine in a human afflicted with a progressive kidney disease and administering an iron chelator to the human. The method can include measuring total urinary protein content, blood urea nitrogen or creatinine in a blood sample before, during or after the administration of an iron chelator.

The invention discloses auricularia auricula polysaccharides energy gel with an anti-fatigue function and belongs to the technical field of food for special use. The energy gel is composed of an auricularia auricula polysaccharides concentrated solution, soy isolate protein, whey protein, fructose, cane sugar, vegetable oil, maltodextrin, gelatin and a quality improver. Weight percentage of the above ingredients is as follows: content of the auricularia auricula polysaccharides concentrated solution is 21-35.5%, content of whey protein is 1-4%, content of soy isolate protein is 1-4%, total content of fructose and cane sugar is 16-40%, total content of vegetable oil is 12-15%, content of maltodextrin is 12-18%, and total content of gelatin and the quality improver is 6-14.3%. The auricularia auricula polysaccharides energy gel can obviously prolong load swimming time of mice and reduce contents of blood lactic acid and blood urea nitrogen, and simultaneously has an effect of increasing glycogen reserves of body and has obvious anti-fatigue and fatigue-removal effects.

The invention discloses a Chinese medicine composition for treating chronic renal failure. Traditional Chinese medicine holds that the chronic renal failure belongs to the category of 'consumptive disease' and 'uroschesis', and the pathogenesis of the chronic renal failure is deficiency of spleen and kidney and turbidity blockade. Therefore, the Chinese medicine composition comprises Chinese medicines including rust-coloured crotalaria herb with root, satyrium root, dried rehmannia root, radix astragali, cinnamon, concha ostreae, radix scutellariae, philippine flemingia root, sticktight and summer purslane, and enema is prepared by a preparation room of the institution. After clinical test, the total effective rate is 97.4%, Scr (serum creatinine) and BUN (blood urea nitrogen) reduction of a control group is obviously superior to that of an existing control group, and the Chinese medicine composition is low in treatment cost, simple and convenient in method and worthy of clinical popularization and application.

The invention discloses a detecting reagent of urea nitrogen and detecting test paper of urea nitrogen. The detecting reagent contains 50-64 KU / L urease, 1.0-1.5 g / L trehalose and 20-30 g / L developing matter. According to the detecting reagent of urea nitrogen, multiple specific enzymes are specifically matched, and the aim of fast and accurately detecting the content of urea nitrogen can be achieved. The detecting test paper of urea nitrogen comprises a reaction base layer, a reaction layer, a flood filtering layer and a sample suction layer. The layers are overlapped to form a siphon system, the anti-interference capacity is higher, interference of endogenous substances is effectively eliminated, and it is further guaranteed that the content of urea nitrogen is fast and accurately detected.

The invention discloses an evaluation method for diet protein intake (DPI) of a chronic kidney disease (CKD) patient. Through research of relationships between a fasting serum blood urea nitrogen / creatinine ratio (BUN / Cr) and a single-time urine urea nitrogen / creatinine ratio (UUN / Cr) of a CKD third-phase patient with a stable illness state, and the diet protein intake (DPI), a DPI simple calculation formula based on the fasting serum BUN / Cr and / or random urine UUN / Cr is established. According to the final calculation formula, it is expected that a traditional method for evaluating the DPI through subsistence of the urine within 24 hours can be replaced by a biochemical detection result of a single-time blood or urine in clinical follow-up. Defects such as complexity, long detection time, poor accuracy, difficult sample subsistence or low patient compliance in the traditional method are overcome. Clinically, the method can be used for clinical follow-up, simple blood drawing or single-time urination, thereby evaluating the DPI. The method can be used for managing the diet protein intake of the CKD patient well, fast and conveniently.

The invention discloses a traditional Chinese medicine composition for improving renal functions and restraining renal fibrosis. Active pharmaceutical ingredients of the traditional Chinese medicine composition comprise, by weight, 10-15 parts of the root of red-rooted salvia, 10-60 parts of astragalus membranaceus, 10-30 parts of herba epimedii, 5-30 parts of sinensis and 3-30 parts of prepared rhubarb. Clinical researches show that 168 patients with chronic renal insufficiency are treated by the traditional Chinese medicine composition, a remarkable clinical effect is obtained, clinical symptoms are reduced, the clinical symptoms of some patients are basically eliminated, the renal functions of the patients can be remarkably improved, blood urea nitrogen (BUN) and creatinine (Scr) are obviously reduced, and total effective rate achieves 88.66%. Animal researches show that the traditional Chinese medicine composition can delay development of chronic renal failure, and the mechanism of the traditional Chinese medicine composition is relative to effects of effectively restraining precipitation of renal tissue collagen and secretion of TGF (transforming growth factor)-beta, accordingly restraining renal fibrosis, and the like. The traditional Chinese medicine composition is low in clinical application cost and excellent in curative effect, and is safe and reliable.

The invention discloses a whitening and anti-fatigue body lotion. The whitening and anti-fatigue body lotion of the invention contains vine tea extract, sweet tea extract and black medicine extract in the weight ratio of (0.2-2): (0.4-2): (0.2~2) mixed plant composition, the whitening anti-fatigue body lotion of the present invention achieves the effect of anti-fatigue by reducing the content of urea nitrogen, has the effects of anti-fatigue and anti-aging, and has good inhibition on tyrosinase Effect, through the inhibition of tyrosinase production to reduce melanin production to achieve whitening effect.

The invention provides medicine for treating uremia and urine protein. The medicine is a mixture of glycoprotein or polysaccharide and protein or polypeptide or protein. The medicine achieves a good treatment effect for uremia and urine protein, and after three treatment courses are completed, the total effective rate is 84-94%; the medicine lowers toxin of uremia and urine protein and remarkably lowers the content of SCr, the content of urine protein and the content of blood urea nitrogen, after three treatment courses are completed, the SCr content of a patient is 282.4-290. micromole / L, the urine protein content is 2.42-2.54 g / 24h, and the blood urea nitrogen content is 14.2-15.0 mmol / L. The medicine improves the nutrition condition of the organism, raises the content of plasma albumin (Alb) and the content of hemoglobin (Hb), improves the immunity, has the advantages of being safe, high in efficiency and free of side effect and has an obvious treatment effect for uremia and urine protein.

The invention relates to a traditional Chinese medicinal composition for treating chronic nephritis which is prepared from 45-65 wt% of bicolor lespedeza, 5-15 wt% of baikal skullcap root, 8-20 wt% of shiwei, 8-20 wt% of astragalus root through the steps of extracting, alcohol deposition, decompression, condensing, and drying.

The invention belongs to the technical field of biology and in particular discloses nano-selenium bifidobacterium longum as well as a preparation method and application thereof. The application of thenano-selenium bifidobacterium longum prepared by the invention to the preparation of medicines or foods for delaying a diabetes mellitus progress comprises: application to medicines or foods for improving physiological index and metabolism conditions of diabetes mellitus, improving pathological changes of diabetes mellitus livers, pancreatic glands and kidneys, improving diabetes mellitus serum creatinine and blood urea nitrogen levels and preventing diabetes mellitus kidney complications or kidney function harms.

The present invention provides one kind of Chinese medicine for treating chronic kidney function failure is prepared with Chinese medicinal materials, including ginseng, astragalus root, white atractylodes rhizome, Chuanxiong rhizome, leech, etc. The medicine has high curative effect, can improve clinical symptoms, reduce urea nitrogen in blood, lower creatinine level, reduce exhausted urine protein, protect kidney function, promote the synthesis of plasma protein, raise plasma protein density, improve body's nutrient state and produce many other positive effects. It is safe clinically and low in production cost.

The invention provides medicine used for treating diabetes mellitus and complications thereof. The medicine is glycoprotein, or a mixture of polysaccharide and protein, or polypeptide or protein. The medicine has an obvious effect of reducing blood glucose of a rat diabetes model, and in the four weeks after the medicine is taken, the blood glucose of a rat is reduced from 27.06-27.19 mmol / L to 11.26-23.41 mmol / L. The medicine is used for treating diabetes mellitus continuously for four weeks, the result shows that a blood glucose value can be reduced obviously, the content of urine protein and the content of urea nitrogen in serum are reduced, the content of triglyceride in the serum is reduced, and the thymus indexes of the rat are increased. The medicine has the obvious effect of reducing the blood glucose and urine sugar of patients with the diabetes mellitus; meanwhile, the medicine has a function of adjusting hyperglycemia, hypertension, hyperlipidemia and high blood viscosity threatening the diabetes mellitus severely. The medicine has the advantages of being safe, efficient and free of side effects, and has the obvious effects of reducing the blood glucose, cholesterol and triglyceride.

The invention discloses the application of dioscin to the preparation of a renal injury protection medicament. Dioscin has a renal injury protection effect, and can be used for preparing the renal injury protection medicament. Dioscin has an obvious lowering effect on NO (Nitric Oxide), TNOS (Total Nitric Oxide Synthase), iNOS (Inducible Nitric Oxide Synthase), MDA (Malondialdehyde), BUN (Blood Urea Nitrogen) and SCr (Serum Creatinine) rise caused by renal injury, has an obvious increasing effect on the reduction of SOD (Superoxide Dismutase), GSH (Glutathione), GSH-Px (Glutathione Peroxidase) and CAT (Catalase) relative to a Model group, and is dose-dependent. After the intervention of dioscin, the phenomena of large-area renal tubular epithelial cell swelling, brush border disappearance, degenerative necrosis of a part of epithelial cells, blockage of lumens by necrotic and exfoliative cellular debris and the like, which are caused by renal injury are obviously alleviated. Dioscin can be used for preparing a medicinal preparation as an active ingredient according to clinical medication needs. Dioscin has the advantages of safety (no toxic or side effects), effectivity, economy, practicability and the like.

The invention discloses an application of peony blood stasis removing preparation in preparing medicaments for preventing and treating diabetic complication. The peony blood stasis removing preparation inhibits the activity of aldose reductase and the formation of a glycosylation end product, and has the new pharmacological functions of reducing the contents of bandicoot blood sugar of diabetic nephropathy (DN), glycosylated hemoglobin (GHb), blood urea nitrogen (BUN) and serum creatinine (Scr), raising the content of high-density lipoprotein of serum, reducing the content of triglyceride andcholesterol, enhancing the nitrogen oxide level of the serum and reducing the content of endothelin and the like. Based on the pharmacological functions, the peony blood stasis removing preparation can be completely used for preventing and treating the chronic diabetic complication, and has precise treating effect, fewer side effects, high safety, abundant resource, easy making process, controllable and stable quality and wide market prospect.

The invention relates to an extract product capable of preventing oxidation, delaying aging, and nourishing heart and cerebral vessels, and a preparation method thereof. According to the preparation method, a grape extract and a mixed fruit powder are prepared firstly, and are mixed with yeast for fermentation, after metabolism of yeast, organic conversion of resveratrol in the grape extract, andanthocyanidin and a plurality of trace elements in the mixed fruit powder is realized, so that adsorption on nutrients is improved, and the biological value is increased. It is confirmed by animal experiments that the extract product is capable of prolonging mouse life time and rat loaded swimming time obviously, reducing blood urea nitrogen content, reducing blood lactic acid accumulation, and increasing hepatic glycogen content, possesses obvious anti-fatigue activity, is capable of increasing the activity of superoxide dismutase in rat serum, and accelerating malonaldehyde removing rate, and possesses obvious anti-oxidation activity. The extract product is prepared from pure natural materials, no chemical raw material is added, no toxic or side effect is caused by long term eating. Theextract product is suitable for fatigable people, people high in cholesterol content, and people with long term smoking and drinking habits.

The invention relates to application of fisetin in preparation of a medicine for preventing and treating uric acid nephropathy, and belongs to the field of medicine. The invention provides application of fisetin or salt thereof in preparation of the medicine for treating and / or preventing the uric acid nephropathy. Animal experiments prove that the fisetin can regulate protein expression of kidney urate transporters URAT1, OAT1, OAT3 and ABCG2, improve uric acid excretion rate and obviously reduce serum creatinine, blood urea nitrogen and blood uric acid levels, also has an effect of inhibiting renal interstitial fibrosis, can obviously reduce expression quantities of fibrosis-related proteins such as alpha-SMA, cologen I and fibronectin, has an exact prevention / treatment effect on the uric acid nephropathy and provides a new choice for clinical medication.

Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to ameliorate renal failure (e.g., improved diuretic effect and / or lowering blood urea nitrogen, proteinuria, and / or serum creatinine levels) in a subject as a result of having been cultured in the presence of an alternating electric field having a specific frequency and a specific field strength. Also included are methods of making and using such compositions.

The invention belongs to the field of biomedicine, and particularly relates to a system for predicting severe acute pancreatitis and application thereof. The system comprises a calculation device for calculating the illness risk according to the heart rate, the respiratory rate, the serum calcium concentration and the blood urea nitrogen. Meanwhile, the invention also provides application of the system in preparation of a product for calculating the risk of severe acute pancreatitis.

The invention discloses a capsule for treatment of nephrotic syndromes, which is prepared with the modern process for processing and refining of raw materials required in the prescription with nine kinds of traditional Chinese herbs, including radix codonopsitis, Astragalus root, prepared rhizome of rehmannia, angelica, American ginseng, phellodendron, Tuckahoe, safflower and peach kernel. The capsule in the invention has the functions of supplementing qi, nourishing yin, clearing away pathogenic heat and removing dampness, and can be used for treatment of nephrotic syndromes, particularly for treatment of nephrotic syndromes with a large amount of albuminuria as the main clinical feature. Based on the pharmacodynamic test and study, the invention can significantly reduce the urokinase protein, blood urea nitrogen and creatinine of animals in the nephrosis model, improve the hematoglobin, ease the pathological lesion of kidney tissues, and promote or quicken the structural recovery of the kidney tissues. The results show that the capsule has significant therapeutic effect on the nephrotic syndromes.

The invention discloses an application of ginsenoside Rg5 (C42H70O12, CAS (chemical abstracts service) No. 186763-78-0) in preparation of a drug for preventing CDDP (cis-diamine dichloroplatinum) induced acute kidney injury, and belongs to the field of research and development of medical products. Animal studies show that compared with a module group, ginsenoside Rg5 can reduce the levels of Cre (creatinine) and BUN (blood urea nitrogen) in serum effectively and increase the levels of SOD (superoxide dismutase) and GSH (glutathione) in kidney tissue; besides, ginsenoside Rg5 can obviously inhibit increase of inflammatory factors such as TNF (tumor necrosis factor)-alpha and IL (interleukin)-1beta in the kidney tissue. Therefore, the drug for preventing the acute kidney injury can be prepared from ginsenoside Rg5 and effective ingredients of ginsenoside Rg5. The drug form can adopts any existing dosage forms such as tablets, capsules, powder injections, injections, pills, soft capsules, granules, patches and the like.

The invention discloses a health beverage capable of replenishing the physical power and relieving the fatigue, belonging to the technical field of foods. The health beverage comprises the following effective components in parts by weight: 100-600 parts of milk protein peptide, 100-300 parts of whey protein powder, 0.6-1.2 parts of taurine, 300-600 parts of saccharides, 0.2-0.8 part of vitamin B group, 0.1-0.4 part of vitamin E and 0.2-0.8 part of vitamin C. According to the health beverage, the consumption of endogenous substances such as saccharides and protein in the human body can be timely replenished, the lactic acid content and the blood urea nitrogen value in the blood can be remarkably decreased, the proteolysis can be effectively reduced, the increase of creatine kinase after the strenuous exercise can be avoided, and meanwhile, the heart recovery after the exercise can be promoted; and fatigue symptoms caused by high working intensity and large amount of exercise can be very obviously improved, the physical power can be rapidly replenished, the fatigue can be relieved, and the endurance and the working efficiency can be improved.

The invention belongs to the technical field of hemodialysis, and discloses a hemodialysis monitoring and nursing control system and method based on the Internet of things. A hemodialysis monitoring and nursing control system based on the Internet of things comprises a heart rate detection module, an arteriovenous pressure detection module, a blood flow detection module, a temperature detection module, a central control module, a bacteria filtration module, a dialysis module, an internet-of-things communication module, an evaluation module, an alarm module and a display module. An urea kineticmodel is analyzed by the evaluation module, the urea clearance rate, the dialysis time and the blood urea nitrogen before and after dialysis of a dialyzer are used for calculating urea distribution volume, and therefore, the protein decomposition rate is calculated, in consideration of individual conditions of different patients, a calculated result is consistent to an actual proteolysis condition; and meanwhile, the safety of hemodialysis is improved through the alarm module.

The invention relates to a lactobacillus acidophilus KBL409 strain and an application of the lactobacillus acidophilus KBL409 strain. The Lactobacillus acidophilus KBL409 strain (registration number KCTC 13518BP) according to the present invention alleviates renal inflammation and the concentration of uremic substances (such as blood urea nitrogen, creatinine, p-cresol and the like) in blood to protect the kidney, and exhibits the effects of proteinuria alleviation, renal mitochondrial function recovery and renal fibrosis inhibition. And therefore, the compound can be effectively applied to improvement of renal function and prevention and treatment of nephropathy (including chronic nephropathy).

The invention discloses application of aspidopterys obcordata extract in preparation of a medicine with the effect of reducing blood uric acid, serum creatinine and / or blood urea nitrogen. Experiments prove that the aspidopterys obcordata dilute ethanol extract has the effects of remarkably reducing blood uric acid, serum creatinine and blood urea nitrogen, has a remarkable effect in the aspect of reducing kidney inflammatory response, can be used for treating uric acid nephropathy, and has a good clinical application prospect.