The invention discloses healthcare wine which is mainly prepared by mixing the components in parts by weight as follows: 5 kg-7.5 kg of wine, 10 g-15 g of Chinese caterpillar fungus, 20 g-25 g of corn cervi pantotrichum, 50 g-60 g of American ginseng, 50 g-60 g of Korean ginseng, 40 g-60 g of ginseng, 6 g-8 g of hippocamp, 50 g-60 g of fructus lycii, 15 g-20 g of rhizoma gastrodiae, 15 g-20 g of radix rehmanniae preparata and 8 g-10 g of ligusticum wallichii, wherein the wine is one of kaoliang spirit, rice wine or white wine. The healthcare wine combines comprehensive efficacy of Chinese caterpillar fungus, corn cervi pantotrichum, American ginseng, Korean ginseng, ginseng, hippocamp, fructus lycii, rhizoma gastrodiae, radix rehmanniae preparata and ligusticum wallichii, and has the efficacy of invigorating vital energy and blood, adjusting physique, building fitness, invigorating kidney, strengthening yang, supplementing strength and the like; and further, the healthcare wind does not contain any chemical agent, has no side effect on a human body, can be taken for a long time, and is easily absorbed by the human body.